S. Honma

发表

Methodological approach to the intracrine study and estimation of DHEA and DHEA-S using liquid chromatography–tandem mass spectrometry (LC–MS/MS)

Y. Shibata, S. Arai, S. Honma, 2015, The Journal of Steroid Biochemistry and Molecular Biology.

Identification of dehydroepiandrosterone metabolites formed from human prostate homogenate using liquid chromatography-mass spectrometry and gas chromatography-mass spectrometry.

A. Mizokami, M. Namiki, Takashi Nakagawa, 2002, Journal of chromatography. A.

The Adrenal Androgen Androstenediol Is Present in Prostate Cancer Tissue after Androgen Deprivation Therapy and Activates Mutated Androgen Receptor

H. Fujita, E. Keller, M. Egawa, 2004, Cancer Research.

Comparison between hippocampus-synthesized and circulation-derived sex steroids in the hippocampus.

H. Mukai, S. Kawato, D. Poirier, 2009, Endocrinology.

Sex steroid synthesis in human skin in situ: The roles of aromatase and steroidogenic acute regulatory protein in the homeostasis of human skin

A. Hachiya, Takayoshi Inoue, H. Sasano, 2012, Molecular and Cellular Endocrinology.

In Vitro Enzyme Assay of CYP21A2 Mutation (R483Q) by A Novel Method Using Liquid Chromatography-Electrospray Ionization Tandem Mass Spectrometry (LC-ESI-MS/MS)

M. Takagi, S. Mizutani, M. Ono, 2008, Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology.

Development of highly sensitive quantification method for testosterone and dihydrotestosterone in human serum and prostate tissue by liquid chromatography–electrospray ionization tandem mass spectrometry

M. Numazawa, K. Yamashita, S. Honma, 2009, Steroids.

Highly sensitive determination of estrone and estradiol in human serum by liquid chromatography–electrospray ionization tandem mass spectrometry

M. Numazawa, K. Yamashita, S. Honma, 2007, Steroids.

Neonatal Exposure to Estrogen in the Wistar Rat Decreases Estrogen Receptor-Beta and Induces Epithelial Proliferation of the Prostate in the Adult

S. Ozono, S. Hayami, S. Honma, 2007, Urologia Internationalis.

High serum dihydrotestosterone examined by ultrasensitive LC‐MS/MS as a predictor of benign prostatic hyperplasia or Gleason score 6 cancer in men with prostate‐specific antigen levels of 3–10 ng/mL

Y. Kubota, Y. Shibata, M. Harada, 2017, Andrology.

Measurement of Peripheral Plasma 18-Oxocortisol Can Discriminate Unilateral Adenoma From Bilateral Diseases in Patients With Primary Aldosteronism

S. Ito, H. Sasano, C. Gomez-Sanchez, 2015, Hypertension.

Impact of pre‐treatment prostate tissue androgen content on the prediction of castration‐resistant prostate cancer development in patients treated with primary androgen deprivation therapy

N. Nonomura, N. Masumori, Y. Kubota, 2013, Andrology.

Development of sensitive derivatization method for aldosterone in liquid chromatography-electrospray ionization tandem mass spectrometry of corticosteroids.

S. Ito, R. Morimoto, F. Satoh, 2008, Journal of chromatography. A.

Simultaneous determination of tetrahydrocortisol, allotetrahydrocortisol and tetrahydrocortisone in human urine by liquid chromatography-electrospray ionization tandem mass spectrometry

M. Numazawa, K. Yamashita, S. Honma, 2008, Steroids.

Synergistic effects of estrogen and androgen on the prostate: Effects of estrogen on androgen‐and estrogen‐receptors, BrdU uptake, immunohistochemical study of AR, and responses to antiandrogens

Kazuto Ito, H. Yamanaka, Kazuhiro Suzuki, 1995, The Prostate.

Ultrastructural study in canine prostatic hyperplasia--effect of antiandrogen.

S. Honma, M. Murakoshi, M. Tagawa, 1998, The Tokai journal of experimental and clinical medicine.

Endocrine environment of benign prostatic hyperplasia: prostate size and volume are correlated with serum estrogen concentration.

H. Yamanaka, Kazuhiro Suzuki, Takanori Suzuki, 1995, Scandinavian journal of urology and nephrology.

The Effects of Anti-androgenic Agents on Metabolism of Testosterone: (II) Effects of Various Drugs on Hepatic Testosterone 5a- and 513-Reductase and its Regulating Factor

S. Tanaka, A. Kambegawa, S. Honma, 2012 .

Title High testosterone levels in prostate tissue obtained by needle biopsycorrelate with poor-prognosis factors in prostate cancer patients

S. Morita, N. Nonomura, N. Masumori, 2019 .

780PHIGH TESTOSTERONE LEVELS IN PROSTATE TISSUE OBTAINED BY NEEDLE BIOPSY CORRELATE WITH POOR PROGNOSIS FACTORS IN PROSTATE CANCER PATIENTS.

Y. Kubota, Y. Shibata, K. Sakamaki, 2014, Annals of oncology : official journal of the European Society for Medical Oncology.

Effect of castration monotherapy on the levels of adrenal androgens in cancerous prostatic tissues

Y. Shibata, Kazuhiro Suzuki, S. Arai, 2008, Steroids.

5αDH‐DOC (5α‐dihydro‐deoxycorticosterone) activates androgen receptor in castration‐resistant prostate cancer

Yusuke Nakamura, T. Miki, H. Nakagawa, 2010, Cancer science.

synthesis of T and DHT from DHEA.

K. Izumi, A. Mizokami, K. Narimoto, 2009 .

[Estrogen formation in the central nervous system and characteristics of aromatase of rat hypothalamus].

Y. Fukabori, S. Honma, Y. Takezawa, 1991, Nihon Naibunpi Gakkai zasshi.

Intratumoral Estrogens and Estrogen Receptors in Human Non–Small Cell Lung Carcinoma

Takashi Suzuki, H. Sasano, Y. Miki, 2008, Clinical Cancer Research.

Biphasic Time Course of the Changes in Aldosterone Biosynthesis Under High-Salt Conditions in Dahl Salt-Sensitive Rats

A. Nishiyama, K. Fukuda, Hideyuki Ito, 2012, Arteriosclerosis, thrombosis, and vascular biology.

Synergistic effects of estrogen with androgen on the prostate—effects of estrogen on the prostate of androgen‐administered rats and 5‐alpha‐reductase activity

H. Yamanaka, Kazuhiro Suzuki, Takanori Suzuki, 1994, The Prostate.

Low serum dehydroepiandrosterone examined by liquid chromatography‐tandem mass spectrometry correlates with poor prognosis in hormone‐naïve prostate cancer

M. Taguri, N. Nonomura, N. Masumori, 2016, The Prostate.

Deletion of macrophage migration inhibitory factor gene induces down regulation of sex hormones and ultrastructural abnormalities in mouse testes.

K. Toshimori, M. Koda, J. Nishihira, 2006, Reproductive toxicology.

Expression and degradation of rat androgen receptor following castration, testosterone replacement and antiandrogens administration: analysis by Western blot and immunohistochemistry.

H. Yamanaka, K. Kurokawa, Y. Fukabori, 1997, The Tohoku journal of experimental medicine.

Immunolocalization of androgen receptor in canine prostatic hyperplasia--effect of antiandrogen.

S. Honma, M. Murakoshi, M. Tagawa, 1998, The Tokai journal of experimental and clinical medicine.

An innovative LC-MS/MS-based method for determining CYP 17 and CYP 19 activity in the adipose tissue of pre- and postmenopausal and ovariectomized women using 13C-labeled steroid substrates.

Y. Shibata, K. Yamashita, S. Honma, 2014, The Journal of clinical endocrinology and metabolism.

Testosterone-lowering activity of canola and hydrogenated soybean oil in the stroke-prone spontaneously hypertensive rat.

H. Okuyama, K. Tatematsu, D. Miyazawa, 2010, The Journal of toxicological sciences.

Changes in testosterone and dihydrotestosterone levels in male rat accessory sex organs, serum, and seminal fluid after castration: establishment of a new highly sensitive simultaneous androgen measurement method.

Y. Shibata, Kazuhiro Suzuki, S. Honma, 2005, Journal of andrology.

Inhibitory Influence of a New Steroidal Anti‐androgen, TZP‐4238, on Prostatic Hyperplasia in the Beagle Dog

H. Yamanaka, S. Honma, M. Murakoshi, 1992, Acta pathologica japonica.

18-oxocortisol measurement in adrenal vein sampling as a biomarker for subclassifying primary aldosteronism.

S. Ito, H. Sasano, C. Gomez-Sanchez, 2011, The Journal of clinical endocrinology and metabolism.

Participation of adrenomedullin and its relation with vascular endothelial growth factor in androgen regulation of prostatic blood flow in vivo.

Y. Shibata, Kazuhiro Suzuki, S. Arai, 2006, Urology.

Effects of a new steroidal antiandrogen, TZP‐4238 (17 α‐acetoxy‐6‐chloro‐2‐oxa‐4, 6‐pregnadiene‐3, 20‐dione), on spontaneously developed canine benign prostatic hyperplasia

H. Yamanaka, Kazuhiro Suzuki, Y. Fukabori, 1995, The Prostate.

Positive effect of prostaglandin on regulation of prostatic blood flow.

Y. Shibata, Kazuhiro Suzuki, S. Arai, 2006, Urology.

Effect of Anti‐androgen (TZP‐4238) on Steroid‐induced Canine Prostatic Hyperplasia

H. Yamanaka, M. Suzuki, S. Honma, 1990, Acta pathologica japonica.

Inhibition of 3α‐hydroxysteroid oxidoreductase and 5α‐reductase activity by antiandrogens and indomethacin in the rat prostate

H. Yamanaka, Y. Fukabori, S. Honma, 1992 .

Simultaneous determination of androstenediol 3-sulfate and dehydroepiandrosterone sulfate in human serum using isotope diluted liquid chromatography-electrospray ionization-mass spectrometry.

A. Mizokami, M. Namiki, E. Koh, 2003, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Prostate cancer stromal cells and LNCaP cells coordinately activate the androgen receptor through synthesis of testosterone and dihydrotestosterone from dehydroepiandrosterone.

E. Keller, K. Izumi, A. Mizokami, 2009, Endocrine-related cancer.

Incomplete testicular feminization syndrome: studies on androgen receptor(AR) function, AR gene analysis, and aromatase activities at puberty and long-term observations of clinical and hormonal features from infancy to puberty.

N. Harada, H. Mori, H. Nawata, 1996, Endocrine journal.

Liquid chromatography–tandem mass spectrometry analysis of human adrenal vein corticosteroids before and after adrenocorticotropic hormone stimulation

Michael R. Kennedy, H. Sasano, Yasuhiro Nakamura, 2012, Clinical endocrinology.

Novel 5α‐steroid reductase (SRD5A3, type‐3) is overexpressed in hormone‐refractory prostate cancer

Yusuke Nakamura, Hidewaki Nakagawa, Kenji Tamura, 2007 .

Novel 5 alpha-steroid reductase (SRD5A3, type-3) is overexpressed in hormone-refractory prostate cancer.

Yusuke Nakamura, Hidewaki Nakagawa, Kenji Tamura, 2008, Cancer science.

Immunolocalization of estrogen‐producing and metabolizing enzymes in benign breast disease: Comparison with normal breast and breast carcinoma

Takashi Suzuki, H. Sasano, Y. Onodera, 2010, Cancer science.

Effect of aromatase inhibitor, TZA‐2209, on the prostate of androstenedione‐treated castrated dogs: Changes in prostate volume and histopathological findings

H. Yamanaka, Kazuhiro Suzuki, Takanori Suzuki, 1996, The Prostate.

Liquid chromatography-tandem mass spectrometry analysis of human adrenal vein 19-carbon steroids before and after ACTH stimulation.

Yasuhiro Nakamura, Hironobu Sasano, Ryo Morimoto, 2013, The Journal of clinical endocrinology and metabolism.

[The metabolism of testosterone in the central nervous system (1). Analysis of testosterone metabolites in the anterior pituitary and hypothalamus using gas chromatography-mass spectrometry (GC-MS), and subcellular localization of testosterone converting enzyme].

Y. Fukabori, S. Honma, A. Kanbegawa, 1984, Nihon Naibunpi Gakkai zasshi.

Aromatase localization in human breast cancer tissues: possible interactions between intratumoral stromal and parenchymal cells.

Takashi Suzuki, H. Sasano, N. Ohuchi, 2007, Cancer research.

Liquid chromatography-tandem mass spectrometry (LC-MS/MS) assay for simultaneous measurement of salivary testosterone and cortisol in healthy men for utilization in the diagnosis of late-onset hypogonadism in males.

M. Namiki, E. Koh, F. Matsui, 2009, Endocrine journal.

Use of novel picolinoyl derivatization for simultaneous quantification of six corticosteroids by liquid chromatography-electrospray ionization tandem mass spectrometry.

Satoshi Tsukamoto, M. Numazawa, K. Yamashita, 2007, Journal of chromatography. A.

New quantification method for estradiol in the prostatic tissues of benign prostatic hyperplasia using liquid chromatography–tandem mass spectrometry

Y. Shibata, Kazuhiro Suzuki, S. Arai, 2010, Steroids.

Direct regulation of prostate blood flow by vascular endothelial growth factor and its participation in the androgenic regulation of prostate blood flow in vivo.

H. Yamanaka, Y. Fukabori, Y. Shibata, 2004, Endocrinology.

[Endocrine environment of benign prostatic hyperplasia--relationships of sex steroid hormone levels with age and the size of the prostate].

H. Yamanaka, Y. Fukabori, T. Suzuki, 1992, Nihon Hinyokika Gakkai zasshi. The japanese journal of urology.

High testosterone levels in prostate tissue obtained by needle biopsy correlate with poor-prognosis factors in prostate cancer patients

S. Morita, N. Nonomura, N. Masumori, 2014, BMC Cancer.

Changes in salivary cortisol and testosterone levels in male chimpanzees during the process of reunion with group members

T. Hasegawa, N. Kutsukake, M. Teramoto, 2023, acta ethologica.

Hormonal and morphologic evaluation of the effects of antiandrogens on the blood supply of the rat prostate.

H. Yamanaka, Y. Fukabori, Y. Shibata, 2003, Urology.

Effects of a new steroidal aromatase inhibitor, TZA-2237, and/or chlormadinone acetate on hormone-induced and spontaneous canine benign prostatic hyperplasia.

K Ito, H. Yamanaka, Y. Shibata, 2000, European journal of endocrinology.

[Effects of antiandrogen TZP-4238 on the prostatic androgen receptor and prostatic androgen in rat].

H. Yamanaka, K. Minato, Y. Fukabori, 1994, Nihon Naibunpi Gakkai zasshi.

Determination of sulfates of androsterone and epiandrosterone in human serum using isotope diluted liquid chromatography-electrospray ionization-mass spectrometry.

A. Mizokami, M. Namiki, E. Koh, 2005, Biomedical chromatography : BMC.

Effect of androgen concentration on seminal vesicle blood flow in rats-establishment of new highly sensitive simultaneous androgen measurement method.

H. Yamanaka, Y. Shibata, Kazuhiro Suzuki, 2005, Urology.

The evaluation of rat prostate blood flow using a laser speckle flowmetry: a comparative study using the microsphere method in castrated and androgen-replenished rats

Yoshihiro Ono, H. Yamanaka, Y. Fukabori, 2004, Urological Research.

Development of prostate cancer in a patient with primary hypogonadism: intratumoural steroidogenesis in prostate cancer tissues

H. Sasano, Y. Shibata, K. Suzuki, 2013, Andrology.