Sue-Ann Mok

发表

Therapeutic Strategies for Restoring Tau Homeostasis.

J. Gestwicki, Z. Young, Sue-Ann Mok, 2018, Cold Spring Harbor perspectives in medicine.

BAG3 Is a Modular, Scaffolding Protein that physically Links Heat Shock Protein 70 (Hsp70) to the Small Heat Shock Proteins.

J. Gestwicki, L. Makley, D. Southworth, 2017, Journal of molecular biology.

Compromised function of the ESCRT pathway promotes endolysosomal escape of tau seeds and propagation of tau aggregation

Marco Y. Hein, L. Grinberg, M. Leonetti, 2019, The Journal of Biological Chemistry.

Pathogenic Tau Impairs Axon Initial Segment Plasticity and Excitability Homeostasis

Shiaoching Gong, Celeste M. Karch, K. Kosik, 2019, Neuron.

Mapping Interactions with the Chaperone Network Reveals Factors that Protect Against Tau Aggregation

J. Gestwicki, Mark R. Wilson, M. Zweckstetter, 2018, Nature Structural & Molecular Biology.

Functional genomics screen identifies proteostasis targets that modulate prion protein (PrP) stability

J. Gestwicki, M. Kampmann, Taylor Arhar, 2021, Cell Stress and Chaperones.

Critical Role of Acetylation in Tau-Mediated Neurodegeneration and Cognitive Deficits

N. Krogan, E. Masliah, L. Ellerby, 2015, Nature Medicine.

Deciphering Network Crosstalk: The Current Status and Potential of miRNA Regulatory Networks on the HSP40 Molecular Chaperone Network

R. Fahlman, Sue-Ann Mok, Lion Budrass, 2021, Frontiers in Genetics.

Prion-Like Propagation Mechanisms in Tauopathies and Traumatic Brain Injury: Challenges and Prospects

W. T. Allison, Sue-Ann Mok, Hadeel Alyenbaawi, 2020, Biomolecules.

A retrograde apoptotic signal originating in NGF-deprived distal axons of rat sympathetic neurons in compartmented cultures

K. Lund, R. Campenot, Sue-Ann Mok, 2009, Cell Research.

Microglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathy

L. Grinberg, W. Seeley, Chao Wang, 2021, Nature Communications.

Tau interactome mapping reveals dynamic processes in synapses and mitochondria associated with neurodegenerative disease

D. Geschwind, N. Krogan, G. Coppola, 2021, bioRxiv.

Promoting tau secretion and propagation by hyperactive p300/CBP via autophagy-lysosomal pathway in tauopathy

A. Boxer, A. Karydas, Chao Wang, 2020, Molecular Neurodegeneration.

Tau Secretion and Propagation Is Regulated by p300/CBP via Autophagy-Lysosomal Pathway in Tauopathy

A. Boxer, A. Karydas, Chao Wang, 2018, bioRxiv.

SIRT1 Deacetylates Tau and Reduces Pathogenic Tau Spread in a Mouse Model of Tauopathy

N. Krogan, E. Masliah, Jeffrey R. Johnson, 2018, The Journal of Neuroscience.

Tau conformers in FTLD-MAPT undergo liquid-liquid phase separation and perturb the nuclear envelope

D. Westaway, J. Safar, N. Daude, 2020, bioRxiv.

Production of compartmented cultures of rat sympathetic neurons

K. Lund, R. Campenot, Sue-Ann Mok, 2009, Nature Protocols.

Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration

D. Geschwind, N. Krogan, Shiaoching Gong, 2022, Cell.

High‐Throughput Screen of Natural Product Extracts in A Yeast Model of Polyglutamine Proteotoxicity

D. Sherman, J. Gestwicki, Pamela J. Schultz, 2014, Chemical biology & drug design.

Compromised function of the ESCRT pathway promotes endolysosomal escape of tau seeds and propagation of tau aggregation

Marco Y. Hein, L. Grinberg, M. Leonetti, 2019, The Journal of Biological Chemistry.

Pathologic tau conformer ensembles induce dynamic, liquid-liquid phase separation events at the nuclear envelope

D. Westaway, L. Molina-Porcel, J. Safar, 2021, BMC Biology.

A nerve growth factor-induced retrograde survival signal mediated by mechanisms downstream of TrkA

R. Campenot, Sue-Ann Mok, S. Mok, 2007, Neuropharmacology.

Competing protein-protein interactions regulate binding of Hsp27 to its client protein tau

D. Agard, Miguel Betegon, J. Gestwicki, 2018, Nature Communications.

Tau activation of microglial cGAS–IFN reduces MEF2C-mediated cognitive resilience

L. Tsai, Shiaoching Gong, Mingrui Zhao, 2023, Nature Neuroscience.

Competing protein-protein interactions regulate binding of Hsp27 to its client protein tau

D. Agard, Miguel Betegon, J. Gestwicki, 2018, Nature Communications.

N-Terminal Fragments of Huntingtin Longer than Residue 170 form Visible Aggregates Independently to Polyglutamine Expansion.

P. Muchowski, D. Hatters, Angelique R. Ormsby, 2017, Journal of Huntington's disease.

Disease associated mutations in tau encode for changes in aggregate structure conformation

Sang-Gyun Kang, Sue-Ann Mok, Allan Yarahmady, 2023, bioRxiv.

Human iPSC 4R tauopathy model uncovers modifiers of tau propagation

Virginia M. Y. Lee, Shiaoching Gong, Mingrui Zhao, 2023, bioRxiv.

A HaloTag® method for assessing the retrograde axonal transport of the p75 neurotrophin receptor and other proteins in compartmented cultures of rat sympathetic neurons

K. Lund, R. Campenot, P. LaPointe, 2013, Journal of Neuroscience Methods.

Promoting tau secretion and propagation by hyperactive p300/CBP via autophagy-lysosomal pathway in tauopathy

A. Boxer, A. Karydas, Chao Wang, 2020, Molecular Neurodegeneration.

Production of compartmented cultures of rat sympathetic neurons

K. Lund, R. Campenot, Sue-Ann Mok, 2009 .