S. Veidal

发表

Biglycan fragmentation in pathologies associated with extracellular matrix remodeling by matrix metalloproteinases

M. Karsdal, M. Larsen, N. Barascuk, 2013, Fibrogenesis & tissue repair.

MMP mediated type V collagen degradation (C5M) is elevated in ankylosing spondylitis.

M. Karsdal, M. Larsen, G. Schett, 2012, Clinical biochemistry.

Ankylosing spondylitis is characterized by an increased turnover of several different metalloproteinase-derived collagen species: a cross-sectional study

M. Karsdal, G. Schett, D. Leeming, 2012, Rheumatology International.

A novel assay for extracellular matrix remodeling associated with liver fibrosis: An enzyme-linked immunosorbent assay (ELISA) for a MMP-9 proteolytically revealed neo-epitope of type III collagen.

M. Karsdal, M. Larsen, L. Rasmussen, 2010, Clinical biochemistry.

Matrix metalloproteinase‐9‐mediated type III collagen degradation as a novel serological biochemical marker for liver fibrogenesis

M. Karsdal, C. Christiansen, B. Vainer, 2010, Liver international : official journal of the International Association for the Study of the Liver.

Animal Models of Type 2 Diabetes, Obesity and Nonalcoholic Steatohepatitis – Clinical Translatability and Applicability in Preclinical Drug Development

J. Jelsing, N. Vrang, T. Sécher, 2019, Translational Research Methods in Diabetes, Obesity, and Nonalcoholic Fatty Liver Disease.

Towards a standard diet-induced and biopsy-confirmed mouse model of non-alcoholic steatohepatitis: Impact of dietary fat source

D. Tabor, J. Jelsing, N. Vrang, 2019, World journal of gastroenterology.

Elafibranor and liraglutide improve differentially liver health and metabolism in a mouse model of non‐alcoholic steatohepatitis

C. Mantzoros, K. Stefanakis, N. Perakakis, 2021, Liver international : official journal of the International Association for the Study of the Liver.

Dual targeting of hepatic fibrosis and atherogenesis by icosabutate, an engineered eicosapentaenoic acid derivative

S. Friedman, J. Kastelein, E. Pieterman, 2020, Liver international : official journal of the International Association for the Study of the Liver.

Validity of biopsy-based drug effects in a diet-induced obese mouse model of biopsy-confirmed NASH

J. Jelsing, N. Vrang, L. Adorini, 2019, BMC Gastroenterology.

Disease Progression and Pharmacological Intervention in a Nutrient-Deficient Rat Model of Nonalcoholic Steatohepatitis

M. Gillum, J. Jelsing, N. Vrang, 2018, Digestive Diseases and Sciences.

Mouse models of nonalcoholic steatohepatitis in preclinical drug development.

N. Vrang, K. Fosgerau, Kristoffer T. G. Rigbolt, 2017, Drug discovery today.

Molecular Characterization of Microvesicular and Macrovesicular Steatosis Shows Widespread Differences in Metabolic Pathways.

J. Jelsing, C. Christoffersen, Kristoffer T. G. Rigbolt, 2019, Lipids.

The Selective Peroxisome Proliferator‐Activated Receptor Gamma Modulator CHS‐131 Improves Liver Histopathology and Metabolism in a Mouse Model of Obesity and Nonalcoholic Steatohepatitis

C. Mantzoros, K. Stefanakis, N. Perakakis, 2020, Hepatology communications.

Hepatoprotective effects of semaglutide, lanifibranor and dietary intervention in the GAN diet‐induced obese and biopsy‐confirmed mouse model of NASH

J. Jelsing, N. Vrang, Andre Broermann, 2022, Clinical and translational science.

Human translatability of the GAN diet-induced obese mouse model of non-alcoholic steatohepatitis

J. Jelsing, N. Vrang, F. Knop, 2020, BMC Gastroenterology.

Empagliflozin Improves Metabolic and Hepatic Outcomes in a Non-Diabetic Obese Biopsy-Proven Mouse Model of Advanced NASH

C. Mantzoros, N. Perakakis, Pavlina Chrysafi, 2021, International journal of molecular sciences.

Non‐alcoholic fatty liver disease alters expression of genes governing hepatic nitrogen conversion

H. Vilstrup, M. Sørensen, F. K. Knop, 2019, Liver international : official journal of the International Association for the Study of the Liver.

ZGN-1061 Improves Metabolic Parameters and Hepatic Pathology in an Obese Mouse Model of Diet-Induced and Biopsy-Confirmed Nonalcoholic Steatohepatitis

T. Hughes, M. Illemann, S. Veidal, 2018, Diabetes.

Obese diet-induced mouse models of nonalcoholic steatohepatitis-tracking disease by liver biopsy.

J. Jelsing, N. Vrang, J. Roth, 2016, World journal of hepatology.

Circulating levels of citrullinated and MMP-degraded vimentin (VICM) in liver fibrosis related pathology.

M. Karsdal, C. Christiansen, B. Vainer, 2012, American journal of translational research.

The neo-epitope specific PRO-C3 ELISA measures true formation of type III collagen associated with liver and muscle parameters.

M. Karsdal, C. Christiansen, K. Henriksen, 2013, American journal of translational research.

Immunological detection of the type V collagen propeptide fragment, PVCP-1230, in connective tissue remodeling associated with liver fibrosis

M. Karsdal, B. Vainer, D. Leeming, 2011, Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals.

Pro-C5, a marker of true type V collagen formation and fibrillation, correlates with portal hypertension in patients with alcoholic cirrhosis

M. Karsdal, J. Trebicka, A. Krag, 2015, Scandinavian journal of gastroenterology.

Circulating Levels of a Collagen Type V Propeptide Fragment in a Carbon Tetrachloride Reversible Model of Liver Fibrosis

M. Karsdal, D. Leeming, E. Vassiliadis, 2012, Biomarker insights.

Procollagen type I N-terminal propeptide (PINP) is a marker for fibrogenesis in bile duct ligation-induced fibrosis in rats

M. Karsdal, B. Vainer, G. Tougas, 2010, Fibrogenesis & tissue repair.

Peptidyl arginine deiminase inhibitor effect on hepatic fibrogenesis in a CCl4 pre-clinical model of liver fibrosis.

M. Karsdal, D. Leeming, E. Vassiliadis, 2013, American journal of translational research.

Low Interleukin-22 Binding Protein Is Associated With High Mortality in Alcoholic Hepatitis and Modulates Interleukin-22 Receptor Expression

S. Hamilton-Dutoit, F. Mortensen, T. Sandahl, 2020, Clinical and translational gastroenterology.

Multi-omics characterization of a diet-induced obese model of non-alcoholic steatohepatitis

B. Blagoev, T. Pers, J. Jelsing, 2020, Scientific Reports.

MMP Mediated Degradation of Type VI Collagen Is Highly Associated with Liver Fibrosis – Identification and Validation of a Novel Biochemical Marker Assay

M. Karsdal, B. Vainer, M. Larsen, 2011, PloS one.

Hepatic transcriptome signatures in patients with varying degrees of nonalcoholic fatty liver disease compared with healthy normal-weight individuals.

J. Jelsing, N. Vrang, T. Vilsbøll, 2019, American journal of physiology. Gastrointestinal and liver physiology.

Phosphodiesterase inhibition mediates matrix metalloproteinase activity and the level of collagen degradation fragments in a liver fibrosis ex vivo rat model

M. Karsdal, D. Leeming, M. Nielsen, 2012, BMC Research Notes.

Interferon lambda 4 genotype and pathway in alcoholic hepatitis

T. Sandahl, H. Grønbaek, H. Vilstrup, 2021, Scandinavian journal of gastroenterology.

Resolution of NASH and hepatic fibrosis by the GLP-1R/GcgR dual-agonist Cotadutide via modulating mitochondrial function and lipogenesis.

M. Larsen, O. McGuinness, L. Jermutus, 2020, Nature metabolism.

Activation of thyroid hormone receptor‐β improved disease activity and metabolism independent of body weight in a mouse model of non‐alcoholic steatohepatitis and fibrosis

A. Kannt, D. Schmoll, P. Wohlfart, 2021, British journal of pharmacology.

Resolution of NASH and hepatic fibrosis by the GLP-1R and GCGR dual-agonist cotadutide via modulating mitochondrial function and lipogenesis

M. Larsen, O. McGuinness, L. Jermutus, 2020, Nature Metabolism.

Metabolic and hepatic effects of liraglutide, obeticholic acid and elafibranor in diet-induced obese mouse models of biopsy-confirmed nonalcoholic steatohepatitis

M. Gillum, J. Jelsing, N. Vrang, 2018, World journal of gastroenterology.

Assessment of proteolytic degradation of the basement membrane: a fragment of type IV collagen as a biochemical marker for liver fibrosis

M. Karsdal, B. Vainer, M. Larsen, 2011, Fibrogenesis & tissue repair.

INT-767 improves histopathological features in a diet-induced ob/ob mouse model of biopsy-confirmed non-alcoholic steatohepatitis

J. Jelsing, N. Vrang, Kristoffer T. G. Rigbolt, 2018, World journal of gastroenterology.

Plasma Pro‐C3 (N‐terminal type III collagen propeptide) predicts fibrosis progression in patients with chronic hepatitis C

M. Karsdal, D. Schuppan, B. Vainer, 2015, Liver international (Print).

Comparative effects of liraglutide, elafibranor and obeticholic acid on NAFLD activity score and fibrosis stage in a diet-induced obese mouse model of biopsy-confirmed NASH

N. Vrang, S. Veidal, M. Feigh, 2017 .

Serum Markers of Liver Fibrosis: Combining the BIPED Classification and the Neo-Epitope Approach in the Development of New Biomarkers

M. Karsdal, B. Vainer, G. Tougas, 2010, Disease markers.

Enzyme‐linked immunosorbent serum assay specific for the 7S domain of Collagen Type IV (P4NP 7S): A marker related to the extracellular matrix remodeling during liver fibrogenesis

M. Karsdal, B. Vainer, D. Leeming, 2012, Hepatology research : the official journal of the Japan Society of Hepatology.

Measurement of CO3-610, a Potential Liver Biomarker Derived from Matrix Metalloproteinase-9 Degradation of Collagen Type III, in a Rat Model of Reversible Carbon-Tetrachloride-Induced Fibrosis

M. Karsdal, N. Barascuk, L. Larsen, 2011, Biomarker insights.

Measurement of matrix metalloproteinase 9-mediated Collagen type III degradation fragment as a marker of skin fibrosis

M. Karsdal, N. Barascuk, L. Larsen, 2011, BMC dermatology.

Phosphodiesterase inhibition mediates matrix metalloproteinase activity and the level of collagen degradation fragments in a liver fibrosis ex vivo rat model

M. Karsdal, D. Leeming, M. Nielsen, 2012, BMC Research Notes.

Combined obeticholic acid and elafibranor treatment promotes additive liver histological improvements in a diet-induced ob/ob mouse model of biopsy-confirmed NASH

J. Jelsing, N. Vrang, L. Adorini, 2019, Scientific Reports.

Enzyme-linked immunosorbent serum assays (ELISAs) for rat and human N-terminal pro-peptide of collagen type I (PINP)--assessment of corresponding epitopes.

M. Karsdal, P. Qvist, B. Riis, 2010, Clinical biochemistry.

A novel marker for assessment of liver matrix remodeling: An enzyme-linked immunosorbent assay (ELISA) detecting a MMP generated type I collagen neo-epitope (C1M)

P. Hägglund, P. Qvist, M. Koizumi, 2011, Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals.