M. Bozdağ

发表

Mycobacterium tuberculosisβ-Carbonic Anhydrases: Novel Targets for Developing Antituberculosis Drugs

C. Supuran, V. Kairys, M. Parikka, 2019, International journal of molecular sciences.

Mechanisms of action of carbonic anhydrase inhibitors

A. Angeli, M. Tanc, M. Bozdağ, 2019, Carbonic Anhydrases.

Synthesis of N'-phenyl-N-hydroxyureas and investigation of their inhibitory activities on human carbonic anhydrases.

C. Supuran, Z. Alothman, A. Angeli, 2018, Bioorganic chemistry.

Coumarins and other fused bicyclic heterocycles with selective tumor-associated carbonic anhydrase isoforms inhibitory activity.

C. Supuran, D. Vullo, A. Alafeefy, 2017, Bioorganic & medicinal chemistry.

Synthesis 4-[2-(2-mercapto-4-oxo-4H-quinazolin-3-yl)-ethyl]-benzenesulfonamides with subnanomolar carbonic anhydrase II and XII inhibitory properties.

Abdul-Malek S. Al-Tamimi, C. Supuran, A. Alafeefy, 2016, Bioorganic & medicinal chemistry.

Synthesis of a new series of dithiocarbamates with effective human carbonic anhydrase inhibitory activity and antiglaucoma action.

C. Supuran, A. Scozzafava, E. Masini, 2015, Bioorganic & medicinal chemistry.

Benzenesulfonamides incorporating bulky aromatic/heterocyclic tails with potent carbonic anhydrase inhibitory activity.

Abdul-Malek S. Al-Tamimi, C. Supuran, A. Scozzafava, 2015, Bioorganic & medicinal chemistry.

Selective inhibition of CA IX over CA XII in breast cancer cells using benzene sulfonamides: Disconnect between CA activity and growth inhibition

C. Supuran, C. Tu, F. Carta, 2018, bioRxiv.

7-Substituted-sulfocoumarins are isoform-selective, potent carbonic anhydrase II inhibitors.

C. Supuran, A. Scozzafava, F. Carta, 2013, Bioorganic & medicinal chemistry.

Synthesis and Evaluation of Carbonic Anhydrase Inhibitors with Carbon Monoxide Releasing Properties for the Management of Rheumatoid Arthritis.

C. Supuran, D. Vullo, C. Ghelardini, 2019, Journal of medicinal chemistry.

Small Molecule Alkoxy Oriented Selectiveness on Human Carbonic Anhydrase II and IX Inhibition

C. Supuran, A. Angeli, F. Carta, 2022, ChemMedChem.

In vitro inhibition of Mycobacterium tuberculosis β-carbonic anhydrase 3 with Mono- and dithiocarbamates and evaluation of their toxicity using zebrafish developing embryos

C. Supuran, D. Vullo, M. Parikka, 2019, Journal of enzyme inhibition and medicinal chemistry.

Thiosemicarbazide-Substituted Coumarins as Selective Inhibitors of the Tumor Associated Human Carbonic Anhydrases IX and XII

C. Supuran, A. Angeli, F. Carta, 2022, Molecules.

Synthesis of a novel affinity gel for the purification of carbonic anhydrases

C. Supuran, O. Arslan, S. Işık, 2015, Journal of enzyme inhibition and medicinal chemistry.

Dithiocarbamates effectively inhibit the β-carbonic anhydrase from the dandruff-producing fungus Malassezia globosa.

C. Supuran, D. Vullo, C. Capasso, 2017, Bioorganic & medicinal chemistry.

Structural insights on carbonic anhydrase inhibitory action, isoform selectivity, and potency of sulfonamides and coumarins incorporating arylsulfonylureido groups.

C. Supuran, A. Scozzafava, E. Masini, 2014, Journal of medicinal chemistry.

Combining the tail and the ring approaches for obtaining potent and isoform-selective carbonic anhydrase inhibitors: solution and X-ray crystallographic studies.

C. Supuran, A. Scozzafava, M. Ferraroni, 2014, Bioorganic & medicinal chemistry.

New 1H‐indole‐2,3‐dione 3‐thiosemicarbazones with 3‐sulfamoylphenyl moiety as selective carbonic anhydrase inhibitors

C. Supuran, N. Karalı, A. Akdemir, 2022, Archiv der Pharmazie.

Benzylaminoethyureido-Tailed Benzenesulfonamides: Design, Synthesis, Kinetic and X-ray Investigations on Human Carbonic Anhydrases

U. Farooq, C. Supuran, G. Zanotti, 2020, International journal of molecular sciences.

Synthesis of new 3-(2-mercapto-4-oxo-4H-quinazolin-3-yl)-benzenesulfonamides with strong inhibition properties against the tumor associated carbonic anhydrases IX and XII.

C. Supuran, D. Vullo, A. Alafeefy, 2017, Bioorganic & medicinal chemistry.

Carbonic anhydrase I, II, IV and IX inhibition with a series of 7-amino-3,4-dihydroquinolin-2(1H)-one derivatives

C. Supuran, Z. Alothman, Silvia Bua, 2017, Journal of enzyme inhibition and medicinal chemistry.

7-Amino-3,4-dihydro-1H-quinolin-2-one, a compound similar to the substituted coumarins, inhibits α-carbonic anhydrases without hydrolysis of the lactam ring

C. Supuran, D. Vullo, F. Carta, 2015, Journal of enzyme inhibition and medicinal chemistry.

Novel small molecule protein arginine deiminase 4 (PAD4) inhibitors.

C. Supuran, A. Scozzafava, P. Tosco, 2013, Bioorganic & medicinal chemistry letters.

Azidothymidine “Clicked” into 1,2,3-Triazoles: First Report on Carbonic Anhydrase–Telomerase Dual-Hybrid Inhibitors

S. Carradori, C. Supuran, T. Peat, 2020, Journal of medicinal chemistry.

Inhibition of carbonic anhydrases by a substrate analog: benzyl carbamate directly coordinates the catalytic zinc ion mimicking bicarbonate binding.

C. Supuran, J. Winum, A. Angeli, 2018, Chemical communications.

State of the Art on Carbonic Anhydrase Modulators for Biomedical Purposes.

C. Supuran, D. Vullo, F. Carta, 2019, Current medicinal chemistry.

Selective inhibition of carbonic anhydrase IX over carbonic anhydrase XII in breast cancer cells using benzene sulfonamides: Disconnect between activity and growth inhibition

C. Supuran, K. Brown, C. Tu, 2018, PloS one.

Selective inhibition of CA IX over CA XII in breast cancer cells using benzene sulfonamides: Disconnect between CA activity and growth inhibition

C. Supuran, K. Brown, C. Tu, 2018, bioRxiv.

N-aryl-N'-ureido-O-sulfamates: Potent and selective inhibitors of the human Carbonic Anhydrase VII isoform with neuropathic pain relieving properties.

C. Supuran, J. Winum, C. Ghelardini, 2019, Bioorganic chemistry.

Benzamide-4-Sulfonamides Are Effective Human Carbonic Anhydrase I, II, VII, and IX Inhibitors

C. Supuran, A. Angeli, M. Bozdağ, 2018, Metabolites.

Synthesis and carbonic anhydrase I, II, VII, and IX inhibition studies with a series of benzo[d]thiazole-5- and 6-sulfonamides

C. Supuran, A. Angeli, F. Carta, 2017, Journal of enzyme inhibition and medicinal chemistry.

Dithiocarbamates with potent inhibitory activity against the Saccharomyces cerevisiae β-carbonic anhydrase

C. Supuran, A. Scozzafava, D. Vullo, 2016, Journal of Enzyme Inhibition and Medicinal Chemistry.

Inhibition of α-, β-, γ-, and δ-carbonic anhydrases from bacteria and diatoms with N′-aryl-N-hydroxy-ureas

C. Supuran, C. Capasso, Z. Alothman, 2018, Journal of enzyme inhibition and medicinal chemistry.

Mono- and di-thiocarbamate inhibition studies of the δ-carbonic anhydrase TweCAδ from the marine diatom Thalassiosira weissflogii

C. Supuran, C. Capasso, Silvia Bua, 2018, Journal of enzyme inhibition and medicinal chemistry.

Benzylaminoethylureido‐Tailed Benzenesulfonamides Show Potent Inhibitory Activity against Bacterial Carbonic Anhydrases

U. Farooq, C. Supuran, C. Capasso, 2020, ChemMedChem.

Carbonic anhydrase inhibitors based on sorafenib scaffold: Design, synthesis, crystallographic investigation and effects on primary breast cancer cells.

Abdul-Malek S. Al-Tamimi, C. Supuran, M. Ferraroni, 2019, European journal of medicinal chemistry.

A Class of 4-Sulfamoylphenyl-ω-aminoalkyl Ethers with Effective Carbonic Anhydrase Inhibitory Action and Antiglaucoma Effects

C. Supuran, A. Scozzafava, E. Masini, 2014, Journal of medicinal chemistry.

"A Sweet Combination": Developing saccharin and acesulfame K structures for selectively targeting the tumor-associated carbonic anhydrases IX and XII.

C. Supuran, Z. Alothman, H. Abdel‐Aziz, 2019, Journal of medicinal chemistry.

Novel 6- and 7-Substituted Coumarins with Inhibitory Action against Lipoxygenase and Tumor-Associated Carbonic Anhydrase IX

C. Supuran, D. Hadjipavlou-Litina, A. Peperidou, 2018, Molecules.

Discovery of 4-Hydroxy-3-(3-(phenylureido)benzenesulfonamides as SLC-0111 Analogues for the Treatment of Hypoxic Tumors Overexpressing Carbonic Anhydrase IX.

C. Supuran, S. Dedhar, M. Ferraroni, 2018, Journal of medicinal chemistry.

Cyclodextrin complexation highly enhances efficacy of arylsulfonylureido benzenesulfonamide carbonic anhydrase inhibitors as a topical antiglaucoma agents.

C. Supuran, A. Scozzafava, E. Masini, 2015, Bioorganic & medicinal chemistry.

N-aryl-N'-ureido-O-sulfamates as potent and selective inhibitors of hCA VB over hCA VA: Deciphering the binding mode of new potential agents in mitochondrial dysfunctions.

C. Supuran, T. Tuccinardi, A. Angeli, 2020, Bioorganic chemistry.

A non-catalytic function of carbonic anhydrase IX contributes to the glycolytic phenotype and pH regulation in human breast cancer cells.

C. Supuran, K. Brown, C. Heldermon, 2019, The Biochemical journal.

A non-catalytic function of carbonic anhydrase IX contributes to the glycolytic phenotype and pH regulation in human breast cancer cells

C. Supuran, K. Brown, C. Heldermon, 2018, bioRxiv.

New Insights into Conformationally Restricted Carbonic Anhydrase Inhibitors

C. Supuran, A. Angeli, F. Carta, 2023, Molecules.

Pain Relieving Effect of-NSAIDs-CAIs Hybrid Molecules: Systemic and Intra-Articular Treatments against Rheumatoid Arthritis

C. Supuran, C. Ghelardini, Bergonzi, 2019, International journal of molecular sciences.

Coumarins and other fused bicyclic heterocycles with selective tumor-associated carbonic anhydrase isoforms inhibitory activity.

C. Supuran, D. Vullo, A. Alafeefy, 2017, Bioorganic & medicinal chemistry.