Minhao Huang

发表

Discovery of the First Examples of Threonine Tyrosine Kinase PROTAC Degraders.

Yong Xu, Xiaoyun Lu, Ke Ding, 2022, Journal of medicinal chemistry.

Comprehensive analysis of m6A/m5C/m1A-related gene expression, immune infiltration, and sensitivity of antineoplastic drugs in glioma

Yongtao Yang, Minhao Huang, Kui Zhang, 2022, Frontiers in Immunology.

Proteome-wide Identification of Off-Targets of a Potent EGFRL858R/T790M Mutant Inhibitor.

P. Hao, Zhengqiu Li, Peng Lyu, 2022, ACS medicinal chemistry letters.

2H-Azirine-based Reagents for Chemoselective Bioconjugation at Carboxyl Residues inside Live Cells.

Xingfeng Yin, W. Ye, Zhengqiu Li, 2020, Journal of the American Chemical Society.

Small molecules targeting RORγt inhibit autoimmune disease by suppressing Th17 cell differentiation

A. Kijlstra, S. Hou, Peizeng Yang, 2020, Cell Death & Disease.

Investigation of Covalent Warheads in the Design of 2-Aminopyrimidine-based FGFR4 Inhibitors.

J. Smaill, Yongheng Chen, Xiaoyun Lu, 2021, ACS medicinal chemistry letters.

Copper-catalyzed trifluoromethylation of trisubstituted allylic and homoallylic alcohols.

Xiaowu Liu, Shuang Jiang, Qiang Zhu, 2015, Chemistry.

Design and Optimization of 3'-(Imidazo[1,2-a]pyrazin-3-yl)-[1,1'-biphenyl]-3-carboxamides as Selective DDR1 Inhibitors.

Yong Xu, Xiaoyun Lu, Zheng-chao Tu, 2020, ACS medicinal chemistry letters.

Pyrido[2, 3-d]pyrimidin-7(8H)-ones as new selective orally bioavailable Threonine Tyrosine Kinase (TTK) inhibitors.

Yong Xu, Xiaoyun Lu, Zheng-chao Tu, 2020, European journal of medicinal chemistry.

A structure-guided optimization of pyrido[2,3-d]pyrimidin-7-ones as selective inhibitors of EGFRL858R/T790M mutant with improved pharmacokinetic properties.

Yong Xu, Lin-jiang Tong, C. Yun, 2017, European journal of medicinal chemistry.

C3 ester side chain plays a pivotal role in the antitumor activity of Maytansinoids.

Yuxi Wang, Jinliang Yang, Minhao Huang, 2021, Biochemical and biophysical research communications.