J. Bickenbach

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Adenovirus-mediated ex vivo immunogene and in vivo combination gene therapy strategies induce a systemic anti-tumor immune defense in the mouse B16 melanoma model.

B. Bonnekoh, D. Roop, T. Krieg, 1998, Advances in experimental medicine and biology.

Transient expression of OCT4 is sufficient to allow human keratinocytes to change their differentiation pathway

R. Eckert, J. Bickenbach, D. Racila, 2010, Gene Therapy.

Long-term culture of murine epidermal keratinocytes.

P. Fleckman, J. Bickenbach, B. Hager, 1999, The Journal of investigative dermatology.

Expression of a dominant-negative type II transforming growth factor β (TGF-β) receptor in the epidermis of transgenic mice blocks TGF-β-mediated growth inhibition

R. Derynck, Xiao‐Jing Wang, D. Roop, 1997 .

Identification of a Population of Epidermal Squamous Cell Carcinoma Cells with Enhanced Potential for Tumor Formation

C. Kerr, M. Vemuri, R. Eckert, 2013, PloS one.

Identification and localization of label-retaining cells in hamster epithelia.

I. Mackenzie, J. Bickenbach, 1984, The Journal of investigative dermatology.

Inhibition of retinoid signaling in transgenic mice alters lipid processing and disrupts epidermal barrier function.

P. Wertz, M. McArthur, D. Roop, 1997, Molecular endocrinology.

CD34+ Blood Cells Accelerate Vascularization and Healing of Diabetic Mouse Skin Wounds

E. Sivan-Loukianova, G. Schatteman, J. Bickenbach, 2003, Journal of Vascular Research.

Targeting expression of a dominant-negative retinoic acid receptor mutant in the epidermis of transgenic mice results in loss of barrier function.

J. Rothnagel, S. Imakado, J. Gordon, 1995, Genes & development.

Loricrin expression is coordinated with other epidermal proteins and the appearance of lipid lamellar granules in development.

D. Roop, J. Rothnagel, J. Greer, 1995, The Journal of investigative dermatology.

Inhibition of skin development by overexpression of transforming growth factor beta 1 in the epidermis of transgenic mice.

A. Roberts, N. Roche, D. Roop, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Genetic disorders of keratin: are scarring alopecias a sub-set?

D. Roop, J. Rothnagel, M. Longley, 1994, Journal of dermatological science.

A Stable Niche Supports Long‐Term Maintenance of Human Epidermal Stem Cells in Organotypic Cultures

P. Boukamp, B. Falkowska-Hansen, H. Bühring, 2008, Stem cells.

Rate of Loss of Tritiated Thymidine Label In Basal Cells In Mouse epithelial tissues

I. Mackenzie, J. Bickenbach, J. McCutecheon, 1986, Cell and tissue kinetics.

Wnt‐3a‐activated human fibroblasts promote human keratinocyte proliferation and matrix destruction

P. Boukamp, H. Stammer, Katrin Sobel, 2015, International journal of cancer.

Treatment with the cancer drugs decitabine and doxorubicin induces human skin keratinocytes to express Oct4 and the OCT4 regulator mir‐145

S. Chinnathambi, J. Bickenbach, M. Winter, 2012, The Journal of dermatology.

Are epidermal stem cells unique with respect to aging?

J. Bickenbach, D. Racila, 2009, Aging.

Somatic Epidermal Stem Cells Can Produce Multiple Cell Lineages During Development

Luchuan Liang, J. Bickenbach, 2002, Stem cells.

Oxygen tension changes the rate of migration of human skin keratinocytes in an age‐related manner

N. Aykin-Burns, J. Bickenbach, C. Ross, 2011, Experimental dermatology.

Isolation, characterization, and culture of epithelial stem cells.

J. Bickenbach, 2005, Methods in molecular biology.

Aging epidermis is maintained by changes in transit-amplifying cell kinetics, not stem cell kinetics.

J. Bickenbach, M. Winter, 2009, The Journal of investigative dermatology.

Functional analysis of activins during mammalian development

R. Jaenisch, A. Bradley, M. Matzuk, 1995, Nature.

Biochemistry of epidermal stem cells.

C. Kerr, M. Vemuri, R. Eckert, 2013, Biochimica et biophysica acta.

Skin keratinocytes pre‐treated with embryonic stem cell‐conditioned medium or BMP4 can be directed to an alternative cell lineage

J. Bickenbach, K. Grinnell, 2007, Cell proliferation.

Label-retaining cells in human embryonic and fetal epidermis.

K. Holbrook, J. Bickenbach, Karen A. Holbrook, 1987, The Journal of investigative dermatology.

Lessons from Loricrin-Deficient Mice

A. Steven, D. Hohl, D. Roop, 2000, The Journal of cell biology.

Lessons from Loricrin-Deficient Mice

A. Steven, D. Hohl, D. Roop, 2000, The Journal of cell biology.

Cells isolated from the epidermis by Hoechst dye exclusion, small size, and negative selection for hematopoietic markers can generate B lymphocyte precursors.

T. Waldschmidt, L. Tygrett, J. Bickenbach, 2008, The Journal of investigative dermatology.

Transgenic models of skin diseases.

D. Roop, J. Rothnagel, D. Greenhalgh, 1993, Archives of dermatology.

Plasticity of epidermal stem cells

M. Stern, J. Bickenbach, 2007, Stem Cell Reviews.

Epidermal stem cells: interactions in developmental environments.

J. Bickenbach, K. Grinnell, 2004, Differentiation; research in biological diversity.

Stem Cells, Differentiation and Renewal Kinetics of Keratinocytes: Implications for Cutaneous Gene Therapy

J. Bickenbach, 2001 .

Telomerase is not an epidermal stem cell marker and is downregulated by calcium.

P. Boukamp, K. Bleuel, G. Schnapp, 1998, The Journal of investigative dermatology.

Mouse epidermal stem cells proceed through the cell cycle

M. Dunnwald, S. Chinnathambi, J. Bickenbach, 2003, Journal of cellular physiology.

As epidermal stem cells age they do not substantially change their characteristics.

Luchuan Liang, M. Stern, S. Chinnathambi, 2004, The journal of investigative dermatology. Symposium proceedings.

Epidermal stem cells are resistant to cellular aging

M. Stern, J. Bickenbach, 2007, Aging cell.

Identification and behavior of label-retaining cells in oral mucosa and skin.

J. Bickenbach, 1981, Journal of dental research.

Selection and extended growth of murine epidermal stem cells in culture.

J. Bickenbach, E. Chism, Emily Chism, 1998, Experimental cell research.

Isolating a pure population of epidermal stem cells for use in tissue engineering

M. Dunnwald, J. Bickenbach, A. Tomanek-Chalkley, 2001, Experimental dermatology.

Transduction of a preselected population of human epidermal stem cells: consequences for gene therapy.

D. Roop, J. Bickenbach, 1999, Proceedings of the Association of American Physicians.

Epithelial stem cells in the skin: definition, markers, localization and functions

G. Cotsarelis, D. Dhouailly, P. Kaur, 1999, Experimental dermatology.

Recapitulation of oral mucosal tissues in long-term organotypic culture.

P. Wertz, S. Chinnathambi, G. Johnson, 2003, The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology.

Epidermal stem cells have the potential to assist in healing damaged tissues.

M. Stern, S. Chinnathambi, J. Bickenbach, 2006, The journal of investigative dermatology. Symposium proceedings.

The mouse keratin 6 isoforms are differentially expressed in the hair follicle, footpad, tongue and activated epidermis.

D. Roop, J. Rothnagel, M. Longley, 1999, Differentiation; research in biological diversity.

Expression of MK6a dominant-negative and C-terminal mutant transgenes in mice has distinct phenotypic consequences in the epidermis and hair follicle.

D. Roop, J. Rothnagel, L. Petherbridge, 1999, Differentiation; research in biological diversity.

A transgenic mouse model that recapitulates the clinical features of both neonatal and adult forms of the skin disease epidermolytic hyperkeratosis.

D. Roop, J. Rothnagel, M. Longley, 1996, Differentiation; research in biological diversity.

TGF alpha and v-fos cooperation in transgenic mouse epidermis induces aberrant keratinocyte differentiation and stable, autonomous papillomas.

D. Roop, D. Greenhalgh, X. Wang, 1995, Oncogene.

Expression of a dominant-negative type II transforming growth factor beta (TGF-beta) receptor in the epidermis of transgenic mice blocks TGF-beta-mediated growth inhibition.

R. Derynck, D. Roop, T. Krieg, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Characterization of loricrin regulation in vitro and in transgenic mice.

D. Roop, J. Rothnagel, D. Disepio, 1999, Differentiation; research in biological diversity.

Label-retaining keratinocytes and Langerhans cells in mouse epithelia

I. Mackenzie, J. Bickenbach, Dr. I. C. Mackenzie, 2004, Cell and Tissue Research.

De-differentiation of mouse interfollicular keratinocytes by the embryonic transcription factor Oct-4.

R. Eckert, J. Bickenbach, Baoli Yang, 2007, The Journal of investigative dermatology.

Immunological gene therapy approaches for malignant melanoma. 2. Preclinical studies and clinical strategies.

B. Bonnekoh, D. Roop, J. Bickenbach, 1997, Skin pharmacology : the official journal of the Skin Pharmacology Society.

Immunological gene therapy approaches for malignant melanoma. 1. Tumor-immunological background.

B. Bonnekoh, D. Roop, J. Bickenbach, 1997, Skin pharmacology : the official journal of the Skin Pharmacology Society.

Three-Dimensional In Vitro Skin and Skin Cancer Models Based on Human Fibroblast-Derived Matrix.

Manuel Berning, P. Boukamp, J. Bickenbach, 2015, Tissue engineering. Part C, Methods.

Epidermal stem cells: characteristics and use in tissue engineering and gene therapy.

M. Dunnwald, J. Bickenbach, 2000, Advances in dermatology.

Proliferation of human embryonic and fetal epidermal cells in organ culture.

K. Holbrook, J. Bickenbach, 1986, The American journal of anatomy.

Montagna Symposium 2010: small molecules: skin as the first line of defense.

M. Kulesz-Martin, R. Gallo, J. Bickenbach, 2011, Journal of Investigative Dermatology.

Human skin and gingival keratinocytes show differential regulation of matrix metalloproteinases when combined with fibroblasts in 3-dimensional cultures.

S. Chinnathambi, J. Bickenbach, 2005, Journal of periodontology.

HSP70 and EndoG Modulate Cell Death by Heat in Human Skin Keratinocytes in vitro

S. Chinnathambi, J. Bickenbach, A. Tomanek-Chalkley, 2007, Cells Tissues Organs.

Treatment with the cancer drugs decitabine and doxorubicin induces human skin keratinocytes to express Oct4 and the OCT4 regulator mir‐145

S. Chinnathambi, J. Bickenbach, M. Winter, 2012, The Journal of dermatology.

Reactivity of epidermal Langerhans cells to a histochemical method for demonstration of beta-glucuronidase.

I. Mackenzie, B. Rittman, J. Bickenbach, 1982, The Journal of investigative dermatology.