Pui Kei Mou

发表

Aurora kinase A inhibition induces synthetic lethality in SMAD4-deficient colorectal cancer cells via spindle assembly checkpoint activation

J. Shim, Xiaoling Xu, Yongjun Dang, 2022, Oncogene.

Synthetic lethality of RB1 and aurora A is driven by stathmin-mediated disruption of microtubule dynamics

J. Shim, Lakhansing Pardeshi, Kaeling Tan, 2020, Nature Communications.

Bromodomain and extra-terminal motif (BET) inhibition is synthetic lethal with loss of SMAD4 in colorectal cancer cells via restoring the loss of MYC repression

J. Shim, Changxiang Shi, Guowen Ren, 2020, Oncogene.

Aurora kinase A, a synthetic lethal target for precision cancer medicine

J. Shim, Changxiang Shi, Shishi Tao, 2021, Experimental & Molecular Medicine.

Natural products targeting cancer cell dependency

J. Shim, Changxiang Shi, Shishi Tao, 2021, The Journal of Antibiotics.

Histone Acetyltransferase (HAT) P300/CBP Inhibitors Induce Synthetic Lethality in PTEN-Deficient Colorectal Cancer Cells through Destabilizing AKT

J. Shim, Changxiang Shi, E. Yang, 2020, International journal of biological sciences.

MDM2 inhibition is synthetic lethal with PTEN loss in colorectal cancer cells via the p53-dependent mechanism

J. Shim, Shishi Tao, Guowen Ren, 2023, International Journal on Biological Sciences.

ER translocon inhibitor ipomoeassin F inhibits triple-negative breast cancer growth via blocking ER molecular chaperones

H. Kwon, J. Shim, Jianhong Zhou, 2023, International journal of biological sciences.

BET inhibition induces synthetic lethality in PTEN deficient colorectal cancers via dual action on p21CIP1/WAF1

J. Shim, Shishi Tao, Guowen Ren, 2024, International journal of biological sciences.