Tao Zhang

发表

A novel USP 9 X substrate TTK contributes to tumorigenesis in non-small-cell lung cancer

Daming Gao, Hu Zhou, Yanting Zhou, 2018 .

Tideglusib and its analogs as inhibitors of Staphylococcus aureus SrtA.

Cai-Guang Yang, L. Lan, Song Yang, 2020, Journal of medicinal chemistry.

A Peptide Binder of E3 Ligase Adaptor SPOP Disrupts Oncogenic SPOP‐Protein Interactions in Kidney Cancer Cells

Hualiang Jiang, Yue Huang, Cai-Guang Yang, 2020, Chinese Journal of Chemistry.

Structure-Based Design of 5-Methylpyrimidopyridone Derivatives as New Wild-Type Sparing Inhibitors of Epidermal Growth Factor Receptor Triple Mutant (EGFRL858R/T790M/C797S).

Wei Xu, Ruibo Wu, Jian Ding, 2019, Journal of medicinal chemistry.

Discovery of JND3229 as a New EGFRC797S Mutant Inhibitor with In Vivo Monodrug Efficacy.

Yi Chen, Jian Ding, C. Yun, 2018, ACS medicinal chemistry letters.

Dysregulation of ClpP by Small-Molecule Activators Used Against Xanthomonas oryzae pv. oryzae Infections.

Cai-Guang Yang, J. Gan, Baoan Song, 2021, Journal of agricultural and food chemistry.

Design, Synthesis, and Biological Evaluation of IRAK4-Targeting PROTACs.

Huibin Zhang, Jinpei Zhou, Jian Ding, 2020, ACS medicinal chemistry letters.

Discovery of N-(3-bromo-1H-indol-5-yl)-quinazolin-4-amine as an effective molecular skeleton to develop reversible/irreversible pan-HER inhibitors.

Lin-jiang Tong, Ting Peng, Yi Chen, 2022, European journal of medicinal chemistry.

Synthesis of silver nanoparticles via traditional Chinese medicine and evaluation of their antibacterial activities

Tao Zhao, Tao Zhang, Yi Yang, 2021, RSC advances.

Anti-infective therapy using species-specific activators of Staphylococcus aureus ClpP

Cai-Guang Yang, J. Gan, Q. Ji, 2022, Nature Communications.

Identification of compound D2923 as a novel anti-tumor agent targeting CSF1R

Yi Chen, Jian Ding, Lin-jiang Tong, 2018, Acta Pharmacologica Sinica.

Design and synthesis of Imidazo[1,2-b]pyridazine IRAK4 inhibitors for the treatment of mutant MYD88 L265P diffuse large B-cell lymphoma.

Huibin Zhang, Jinpei Zhou, Jian Ding, 2020, European journal of medicinal chemistry.

Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia.

Hualiang Jiang, Yue Huang, Cai-Guang Yang, 2019, Cancer cell.

Design and synthesis of selective degraders of EGFRL858R/T790M mutant.

Lin-jiang Tong, Xiaoyun Lu, Hua Xie, 2020, European journal of medicinal chemistry.

Discovery of Potent and Noncovalent Reversible EGFR Kinase Inhibitors of EGFRL858R/T790M/C797S.

Xia Wang, Honglin Li, Zhenjiang Zhao, 2019, ACS medicinal chemistry letters.

Discovery and Structural Optimization of N5-Substituted 6,7-Dioxo-6,7-dihydropteridines as Potent and Selective Epidermal Growth Factor Receptor (EGFR) Inhibitors against L858R/T790M Resistance Mutation.

Xia Wang, Honglin Li, Zhenjiang Zhao, 2016, Journal of medicinal chemistry.

Ubiquitylation of p62/sequestosome1 activates its autophagy receptor function and controls selective autophagy upon ubiquitin stress

L. Hui, Juan Du, D. Finley, 2017, Cell Research.

A novel USP9X substrate TTK contributes to tumorigenesis in non-small-cell lung cancer

Daming Gao, Hu Zhou, Yanting Zhou, 2018, Theranostics.

Discovery and biological evaluation of N-(3-(7-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)-4-methyl-2-oxo-2H-pyrimido[4,5-d][1,3]oxazin-1(4H)-yl)phenyl)acrylamide as potent Bruton’s tyrosine kinase inhibitors

Jian Ding, D. Dou, Lin-jiang Tong, 2019, Acta Pharmacologica Sinica.

C11, a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor, suppresses breast cancer metastasis and angiogenesis

Yi Chen, Xianwen Cao, Jian Ding, 2018, Acta Pharmacologica Sinica.

LS‐106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo

Kai Yu, Yi Chen, Jian Ding, 2021, Cancer science.

Identification of metabolic vulnerabilities of receptor tyrosine kinases-driven cancer

Min Huang, Jian Ding, Hanlin Zeng, 2019, Nature Communications.

Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance

Yi Chen, Jian Ding, Lin-jiang Tong, 2020, Molecular Cancer.

Hypophosphorylation of residue Y1045 leads to defective downregulation of EGFRvIII

Careen K. Tang, Hong Yu, W. Han, 2006, Cancer biology & therapy.

Assessment of the structure-activity relationship and antileukemic activity of diacylpyramide compounds as human ClpP agonists.

Cai-Guang Yang, J. Gan, Tao Zhang, 2023, European journal of medicinal chemistry.

Structure-activity Relationship of SPOP Inhibitors Against Kidney Cancer.

Hualiang Jiang, Cai-Guang Yang, C. Luo, 2020, Journal of medicinal chemistry.