B. Slingsby

发表

Discovery of 2-[(2,4-dichlorophenyl)amino]-N-[(tetrahydro- 2H-pyran-4-yl)methyl]-4-(trifluoromethyl)- 5-pyrimidinecarboxamide, a selective CB2 receptor agonist for the treatment of inflammatory pain.

I. Chessell, A. Naylor, C. O'shaughnessy, 2007 .

Discovery and structure-activity relationships of a series of pyroglutamic acid amide antagonists of the P2X7 receptor.

S. Senger, P. Beswick, Robert J Gleave, 2010, Bioorganic & medicinal chemistry letters.

6-heteroaryl-pyrazolo[3,4-b]pyridines: potent and selective inhibitors of glycogen synthase kinase-3 (GSK-3).

A. Naylor, A. Takle, J. Witherington, 2003, Bioorganic & medicinal chemistry letters.

Synthesis and evaluation of 3-amino-6-aryl-pyridazines as selective CB(2) agonists for the treatment of inflammatory pain.

Andrew J. Brown, P. Beswick, Robert J Gleave, 2010, Bioorganic & medicinal chemistry letters.

2-Amino-5-aryl-pyridines as selective CB2 agonists: synthesis and investigation of structure-activity relationships.

Andrew J. Brown, P. Beswick, Robert J Gleave, 2009, Bioorganic & medicinal chemistry letters.

Pyridine-3-carboxamides as novel CB(2) agonists for analgesia.

I. Wall, I. Chessell, A. Naylor, 2009, Bioorganic & medicinal chemistry letters.

Discovery of 1-[4-(3-chlorophenylamino)-1-methyl-1H-pyrrolo[3,2-c]pyridin-7-yl]-1-morpholin-4-ylmethanone (GSK554418A), a brain penetrant 5-azaindole CB2 agonist for the treatment of chronic pain.

Michael A. Briggs, I. Chessell, A. Naylor, 2009, Journal of medicinal chemistry.

Discovery of 2-[(2,4-dichlorophenyl)amino]-N-[(tetrahydro- 2H-pyran-4-yl)methyl]-4-(trifluoromethyl)- 5-pyrimidinecarboxamide, a selective CB2 receptor agonist for the treatment of inflammatory pain.

I. Chessell, A. Naylor, C. O'shaughnessy, 2007, Journal of medicinal chemistry.

Reissert compound chemistry. Part 5. Formation of pyrrolo[1,2-a]-quinolines and pyrrolo[2,1-a]isoquinolines

B. Slingsby, R. Budhram, B. Uff, 1977 .

The inhibition of human cytomegalovirus (hCMV) protease by hydroxylamine derivatives.

R. Ife, D. Haigh, D. G. Smith, 1999, Bioorganic & medicinal chemistry letters.

2-(Alkylthio)pyrimidin-4-ones as novel, reversible inhibitors of lipoprotein-associated phospholipase A2.

D. Tew, H. Boyd, I. Stansfield, 2000, Bioorganic & medicinal chemistry letters.

3-Anilino-4-arylmaleimides: potent and selective inhibitors of glycogen synthase kinase-3 (GSK-3).

M. Saunders, R. Ife, D. Haigh, 2001, Bioorganic & medicinal chemistry letters.

5-aryl-pyrazolo[3,4-b]pyridazines: potent inhibitors of glycogen synthase kinase-3 (GSK-3).

R. Ife, D. M. Hickey, D. Haigh, 2003, Bioorganic & medicinal chemistry letters.

ATP-citrate lyase as a target for hypolipidemic intervention. Design and synthesis of 2-substituted butanedioic acids as novel, potent inhibitors of the enzyme.

D. Tew, A. Shaw, P. Groot, 1996, Journal of medicinal chemistry.

6-aryl-pyrazolo[3,4-b]pyridines: potent inhibitors of glycogen synthase kinase-3 (GSK-3).

A. Naylor, A. Takle, J. Witherington, 2003, Bioorganic & Medicinal Chemistry Letters.

Non-basic histamine H1-antagonists. I: Synthesis and biological evaluation of some substituted 2-(2-pyridylaminoalkylamino) pyrimidones and related compounds

G. J. Durant, C. Ganellin, M. Parsons, 1989 .

2-Amino-5-aryl-pyridines as selective CB2 agonists: synthesis and investigation of structure-activity relationships.

Andrew J. Brown, P. Beswick, Robert J Gleave, 2009, Bioorganic & medicinal chemistry letters.