C. Wittevrongel

发表

therapeutic implications PACAP and its receptor VPAC1 regulate megakaryocyte maturation

J. Vermylen, M. Hoylaerts, R. Vos, 2013 .

The transcription factor GATA1 regulates NBEAL2 expression through a long-distance enhancer

Marloes R. Tijssen, Chantal Thys, Kathleen Freson, 2017, Haematologica.

PACAP and its receptor VPAC1 regulate megakaryocyte maturation: therapeutic implications.

J. Vermylen, M. Hoylaerts, R. De vos, 2008, Blood.

Thrombogenicity of beta 2-glycoprotein I-dependent antiphospholipid antibodies in a photochemically induced thrombosis model in the hamster.

J. Vermylen, M. Hoylaerts, J. Arnout, 2003, Blood.

NPC1 defect results in abnormal platelet formation and function: studies in Niemann-Pick disease type C1 patients and zebrafish.

J. Jaeken, R. De vos, C. Van Geet, 2013, Human molecular genetics.

Compound heterozygous mutations in the GNAS gene of a boy with morbid obesity, thyroid-stimulating hormone resistance, pseudohypoparathyroidism, and a prothrombotic state.

F. de Zegher, J. Jaeken, C. Van Geet, 2008, The Journal of clinical endocrinology and metabolism.

A compound heterozygous mutation in glycoprotein VI in a patient with a bleeding disorder

C. Hermans, P. Smethurst, C. Van Geet, 2009, Journal of thrombosis and haemostasis : JTH.

A dominant gain-of-function mutation in universal tyrosine kinase SRC causes thrombocytopenia, myelofibrosis, bleeding, and bone pathologies

Sylvia Richardson, Kathleen Stirrups, Wendy N. Erber, 2016, Science Translational Medicine.

Methylation Defect in Imprinted Genes Detected in Patients with an Albright's Hereditary Osteodystrophy Like Phenotype and Platelet Gs Hypofunction

D. Lambrechts, K. Devriendt, F. de Zegher, 2012, PloS one.

Pseudohypoparathyroidism type Ib with disturbed imprinting in the GNAS1 cluster and Gsalpha deficiency in platelets.

J. Vermylen, M. Hoylaerts, C. Van Geet, 2002, Human molecular genetics.

Functional polymorphisms in the paternally expressed XLalphas and its cofactor ALEX decrease their mutual interaction and enhance receptor-mediated cAMP formation.

J. Vermylen, F. de Zegher, M. Hoylaerts, 2003, Human molecular genetics.

Interaction of ionizing irradiation with steroid receptors in human breast cancer cells.

J. Janssens, W. D. De Loecker, C. Wittevrongel, 1984, Cancer research.

Beta-2-glycoprotein I Dependent Lupus Anticoagulants Form Stable Bivalent Antibody Beta-2-Glycoprotein I Complexes on Phospholipid Surfaces

J. Vermylen, M. Hoylaerts, J. Arnout, 1998, Thrombosis and Haemostasis.

Increased Gs signalling in platelets and impaired collagen activation, due to a defect in the dystrophin gene, result in increased blood loss during spinal surgery.

N. Goemans, M. Hoylaerts, R. De vos, 2008, Human molecular genetics.

Regulator of G‐protein signaling 18 controls megakaryopoiesis and the cilia‐mediated vertebrate mechanosensory system

R. Gijsbers, Z. Debyser, J. Metz, 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

The TUBB1 Q43P functional polymorphism reduces the risk of cardiovascular disease in men by modulating platelet function and structure.

J. Vermylen, L. Vanhees, R. De vos, 2005, Blood.

Effect of presurgical radiotherapy on the steroid receptor concentrations in primary breast carcinoma.

J. C. Mulier, J. Bonté, J. Janssens, 1981, European journal of cancer.

What’s new in using platelet research? To unravel thrombopathies and other human disorders

K. Freson, C. Thys, V. Labarque, 2007, European Journal of Pediatrics.

No evidence for GNAS copy number variants in patients with features of Albright's hereditary osteodystrophy and abnormal platelet Gs activity

J. D. Favero, K. Freson, C. Thys, 2012, Journal of Human Genetics.

GNAS defects identified by stimulatory G protein alpha-subunit signalling studies in platelets.

Chantal Thys, Kathleen Freson, F. de Zegher, 2008, The Journal of clinical endocrinology and metabolism.

The pituitary adenylate cyclase-activating polypeptide is a physiological inhibitor of platelet activation.

J. Vermylen, Y. Tomiyama, M. Hoylaerts, 2004, The Journal of clinical investigation.

Platelet studies in autism spectrum disorder patients and first-degree relatives

H. Peeters, K. Devriendt, K. Freson, 2015, Molecular Autism.

Effects of ionizing irradiation on the estradiol and progesterone receptors in rat mammary tumors.

J. Lauwerijns, J. Janssens, W. D. De Loecker, 1981, Cancer research.

The effects of ionizing irradiation on the sedimentation coefficient of cytoplasmic steroid receptors in rat mammary tumors.

J. Janssens, W. D. De Loecker, C. Wittevrongel, 1983, European journal of cancer & clinical oncology.

Monoclonal Antibodies against Beta-2-Glycoprotein I: Use as Reference Material for Lupus Anticoagulant Tests

J. Vermylen, J. Arnout, M. Vanrusselt, 1998, Thrombosis and Haemostasis.

High-Dose Intravenous Immunoglobulin Treatment of a Pregnant Patient with an Antiphospholipid Syndrome: Immunological Changes Associated with a Successful Outcome

J. Vermylen, J. Arnout, J. Vermylen, 1994, Thrombosis and Haemostasis.

Severe Gastrointestinal Bleeding and Thrombocytopenia in a Child With an Anti-GATA1 Autoantibody

Chantal Thys, Kathleen Freson, R. Vos, 2010, Pediatric Research.

Guanine nucleotide-dependent inhibition of phospholipase C in human endothelial cells.

H. Deckmyn, J. Vermylen, J. Kienast, 1990, The Journal of biological chemistry.

A myelodysplastic syndrome associated with a clonal GATA1 mutation

P. Vyas, P. Vandenberghe, K. Freson, 2008 .

Sodium fluoride induced activation of phospholipase C in intact human platelets does not depend on ADP, PAF or arachidonate products.

J. Arnout, H. Deckmyn, J. Vermylen, 1993, Thrombosis research.

Unravelling the disease mechanism for TSPYL1 deficiency.

K. Downes, H. Van Esch, B. Ceulemans, 2020, Human molecular genetics.

The TUBB 1 Q 43 P functional polymorphism reduces the risk of cardiovascular disease in men by modulating platelet function and structure

J. Vermylen, L. Vanhees, K. Peerlinck, 2005 .

Methylome analysis for spina bifida shows SOX18 hypomethylation as a risk factor with evidence for a complex (epi)genetic interplay to affect neural tube development

Y. Moreau, K. Jansen, K. Freson, 2016, Clinical Epigenetics.

DNA methylation analysis of Homeobox genes implicates HOXB7 hypomethylation as risk factor for neural tube defects

Y. Moreau, D. Lambrechts, K. Jansen, 2015, Epigenetics.

Platelet Gs hypofunction and abnormal morphology resulting from a heterozygous RGS2 mutation

M. Di Michele, E. Waelkens, R. De vos, 2010, Journal of thrombosis and haemostasis : JTH.

structure cardiovascular disease in men by modulating platelet function and The TUBB1 Q43P functional polymorphism reduces the risk of

J. Vermylen, L. Vanhees, K. Peerlinck, 2013 .

structure cardiovascular disease in men by modulating platelet function and Q43P functional polymorphism reduces the risk of TUBB1 The

J. Vermylen, L. Vanhees, K. Peerlinck, 2009 .

Platelet Gs hypofunction and abnormal morphology resulting from a heterozygous RGS2 mutation

K. Freson, C. Thys, C. Geet, 2010, Journal of thrombosis and haemostasis : JTH.

A compound heterozygous mutation in glycoprotein VI in a patient with a bleeding disorder

C. Hermans, P. Smethurst, K. Freson, 2009, Journal of thrombosis and haemostasis : JTH.

Mechanisms of action and targets for actual and future antiplatelet drugs.

K. Freson, C. Thys, C. Wittevrongel, 2006, Mini reviews in medicinal chemistry.

NPC1 defect results in abnormal platelet formation and function: studies in Niemann-Pick disease type C1 patients and zebrafish.

J. Jaeken, R. De vos, K. Freson, 2013, Human molecular genetics.