W. Voegtli

发表

A high density CHO-S transient transfection system: Comparison of ExpiCHO and Expi293.

Robert L. Ballinger, T. Panavas, C. Liu, 2017, Protein expression and purification.

Highly potent and selective 3-N-methylquinazoline-4(3H)-one based inhibitors of B-Raf(V600E) kinase.

E. Laird, S. Gloor, G. Vigers, 2014, Bioorganic & medicinal chemistry letters.

The discovery of potent and selective pyridopyrimidin-7-one based inhibitors of B-RafV600E kinase.

Tyler T. Risom, E. Laird, S. Gloor, 2012, Bioorganic & medicinal chemistry letters.

Structures of the yeast ribonucleotide reductase Rnr2 and Rnr4 homodimers.

A. Rosenzweig, J. Stubbe, D. Perlstein, 2004, Biochemistry.

Potent and selective aminopyrimidine-based B-Raf inhibitors with favorable physicochemical and pharmacokinetic properties.

E. Laird, Y. Ran, G. Hatzivassiliou, 2012, Journal of medicinal chemistry.

Discovery and preclinical development of AR453588 as an anti-diabetic glucokinase activator.

Ashutosh Kumar Singh, F. Sullivan, E. Wallace, 2019, Bioorganic & medicinal chemistry.

Novel Series of Potent Glucokinase Activators Leading to the Discovery of AM-2394.

A. Cheng, P. Coward, J. Medina, 2016, ACS medicinal chemistry letters.

ARRY-520, a novel KSP inhibitor with potent activity in hematological and taxane-resistant tumor models.

B. Tunquist, D. Walker, C. Lemieux, 2009, Anticancer Research.

Non-oxime inhibitors of B-Raf(V600E) kinase.

E. Laird, B. Brandhuber, G. Vigers, 2011, Bioorganic & medicinal chemistry letters.

Discovery of 2-pyridylureas as glucokinase activators.

M. McVean, K. Condroski, W. deWolf, 2014, Journal of medicinal chemistry.

Crystal Structure of Human AKT1 with an Allosteric Inhibitor Reveals a New Mode of Kinase Inhibition

B. Brandhuber, G. Vigers, W. Voegtli, 2010, PloS one.

Pyrazolopyridine Inhibitors of B-Raf(V600E). Part 1: The Development of Selective, Orally Bioavailable, and Efficacious Inhibitors.

Tyler Risom, Zhaoyang Wen, Ignacio Aliagas, 2011, ACS medicinal chemistry letters.

Crystal Structure of the Ribonucleotide Reductase R2 Mutant that Accumulates a μ-1,2-Peroxodiiron(III) Intermediate during Oxygen Activation

Jeffrey W. Baldwin, J. Martin Bollinger, J. Baldwin, 2000 .

The Structure of Aip1p, a WD Repeat Protein That Regulates Cofilin-mediated Actin Depolymerization*

David K Wilson, W. Voegtli, Y. Madrona, 2003, Journal of Biological Chemistry.

Alloxan Diabetes and Glycogen Phosphorolysis in Rats

W. Voegtli, D. Staehelin, 1947, Nature.

Rational reprogramming of the R2 subunit of Escherichia coli ribonucleotide reductase into a self-hydroxylating monooxygenase.

J. Baldwin, C. Krebs, J. Bollinger, 2001, Journal of the American Chemical Society.

Structure of the yeast ribonucleotide reductase Y2Y4 heterodimer

A. Rosenzweig, J. Stubbe, D. Perlstein, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Imidazo[4,5-b]pyridine inhibitors of B-Raf kinase.

Zhaoyang Wen, Joachim Rudolph, E. Laird, 2013, Bioorganic & medicinal chemistry letters.

Pyrazolopyridine inhibitors of B-RafV600E. Part 2: structure-activity relationships.

Ellen R. Laird, Tyler Risom, Zhaoyang Wen, 2011, Bioorganic & medicinal chemistry letters.

Pyrazolopyridine inhibitors of B-Raf(V600E). Part 4: rational design and kinase selectivity profile of cell potent type II inhibitors.

Tyler T. Risom, E. Laird, S. Gloor, 2012, Bioorganic & medicinal chemistry letters.

Structure of the bacteriophage lambda Ser/Thr protein phosphatase with sulfate ion bound in two coordination modes.

A. Rosenzweig, N. J. Reiter, F. Rusnak, 2000, Biochemistry.

Variable coordination geometries at the diiron(II) active site of ribonucleotide reductase R2.

J. Baldwin, J. Bollinger, L. Saleh, 2003, Journal of the American Chemical Society.

Identification of a new class of glucokinase activators through structure-based design.

K. Condroski, W. deWolf, W. Voegtli, 2013, Journal of medicinal chemistry.

Producing amyloid fibrils in vitro: A tool for studying AL amyloidosis

D. Sizova, M. Batonick, W. Voegtli, 2023, Biochemistry and biophysics reports.

Structure of the Bacteriophage λ Ser/Thr Protein Phosphatase with Sulfate Ion Bound in Two Coordination Modes

A. Rosenzweig, N. J. Reiter, F. Rusnak, 2000 .