A. Brown

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The mechanism for the disparate actions of calcitriol and 22-oxacalcitriol in the intestine.

E. Slatopolsky, C. Ritter, N. Kubodera, 1993, Endocrinology.

Differential catabolism of 22-oxacalcitriol and 1,25-dihydroxyvitamin D3 by normal human peripheral monocytes.

A. Dusso, E. Slatopolsky, M. Gallieni, 1993, Endocrinology.

A. Brown, 1999, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Phosphorus restriction prevents parathyroid gland growth. High phosphorus directly stimulates PTH secretion in vitro.

A. Dusso, E. Slatopolsky, P. N. MacDonald, 1996, The Journal of clinical investigation.

1Alpha,25-dihydroxy-3-epi-vitamin D3, a natural metabolite of 1alpha,25-dihydroxyvitamin D3, is a potent suppressor of parathyroid hormone secretion.

E. Slatopolsky, W. Okamura, C. Ritter, 1999, Journal of cellular biochemistry.

The noncalcemic analogue of vitamin D, 22-oxacalcitriol, suppresses parathyroid hormone synthesis and secretion.

Alex J. Brown, T. Mori, A. Dusso, 1989, Contributions to nephrology.

A new analog of calcitriol, 19-nor-1,25-(OH)2D2, suppresses parathyroid hormone secretion in uremic rats in the absence of hypercalcemia.

E. Slatopolsky, J. Morrissey, C. Ritter, 1995, American journal of kidney diseases : the official journal of the National Kidney Foundation.

25-Hydroxyvitamin D(3) suppresses PTH synthesis and secretion by bovine parathyroid cells.

H. Armbrecht, E. Slatopolsky, C. Ritter, 2006, Kidney international.

Mechanism of vitamin D action and its regulation.

A. Dusso, A. Brown, 1998, American journal of kidney diseases : the official journal of the National Kidney Foundation.

Comparison of fast and slow pressor effects of angiotensin II in the conscious rat.

A. Lever, J. Morton, J. Casals-stenzel, 1981, The American journal of physiology.

Ascorbic acid induces a favorable lipoprotein profile in women.

S. Samman, L. Gatto, A. Brown, 1996, Journal of the American College of Nutrition.

Solubilization and reconstitution of chick renal mitochondrial 25-hydroxyvitamin D3 24-hydroxylase.

H. DeLuca, A. Brown, M. Burgos-Trinidad, 1986, Biochemistry.

Loss of calcium responsiveness in cultured bovine parathyroid cells is associated with decreased calcium receptor expression.

E. Brown, E. Slatopolsky, C. Ritter, 1995, Biochemical and biophysical research communications.

Production of 10-oxo-19-nor-25-hydroxyvitamin D3 by solubilized kidney mitochondria from chick and rat.

H. DeLuca, A. Brown, 1985, Journal of Biological Chemistry.

Vitamin-D

A. Dusso, E. Slatopolsky, A. Brown, 2020, Reactions Weekly.

1,25-(OH)2D receptors are decreased in parathyroid glands from chronically uremic dogs.

A. Dusso, E. Slatopolsky, A. Brown, 1989, Kidney international.

Enhancement of macrophage survival and DNA synthesis by oxidized-low-density-lipoprotein (LDL)-derived lipids and by aggregates of lightly oxidized LDL.

J. Hamilton, W. Jessup, G. Whitty, 2001, The Biochemical journal.

Cholesterol and oxysterol metabolism and subcellular distribution in macrophage foam cells. Accumulation of oxidized esters in lysosomes.

R. Dean, I. Gelissen, Andrew J. Brown, 2000, Journal of lipid research.

Free and esterified oxysterol: formation during copper-oxidation of low density lipoprotein and uptake by macrophages.

R. Dean, Andrew J. Brown, W. Jessup, 1996, Journal of lipid research.

Interaction of caveolin with 7-ketocholesterol.

K. Stanley, A. Brown, L. S. Sleer, 2001, Atherosclerosis.

Oxysterol efflux from macrophage foam cells: the essential role of acceptor phospholipid.

R. Dean, I. Gelissen, K. Rye, 1999, Journal of lipid research.

Trans fatty acids affect lipoprotein metabolism in rats.

S. Samman, M. Lyons, L. Gatto, 2002, The Journal of nutrition.

7-Ketocholesterol delivered to mice in chylomicron remnant-like particles is rapidly metabolised, excreted and does not accumulate in aorta.

M. Lyons, A. Brown, 2001, Biochimica et biophysica acta.

Trans fatty acids and cholesterol metabolism: mechanistic studies in rats and rabbits fed semipurified diets.

S. Samman, M. Lyons, L. Gatto, 2001, International journal of food sciences and nutrition.

Cloning and localization of Rab3 isoforms in bovine, rat, and human parathyroid glands.

E. Slatopolsky, Y. Abu-Amer, C. Ritter, 1999, Biochemical and biophysical research communications.

A new analog of 1,25-(OH)2D3, 19-NOR-1,25-(OH)2D2, suppresses serum PTH and parathyroid gland growth in uremic rats without elevation of intestinal vitamin D receptor content.

A. Dusso, E. Slatopolsky, A. Brown, 1997, American journal of kidney diseases : the official journal of the National Kidney Foundation.

Extrarenal production of calcitriol in normal and uremic humans.

J. Delmez, A. Dusso, E. Slatopolsky, 1991, The Journal of clinical endocrinology and metabolism.

A rapid assay for 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D 24-hydroxylase.

H. DeLuca, A. Brown, M. Burgos-Trinidad, 1990, Analytical biochemistry.

Rapid hepatic metabolism of 7-ketocholesterol in vivo: implications for dietary oxysterols.

S. Samman, M. Lyons, L. Gatto, 1999, Journal of lipid research.

Therapeutic uses of vitamin D analogues.

A. Brown, A. Brown, 2001, American journal of kidney diseases : the official journal of the National Kidney Foundation.

Differential effects of 1,25-dihydroxy-vitamin D3 and 19-nor-1,25-dihydroxy-vitamin D2 on calcium and phosphorus resorption in bone.

E. Slatopolsky, A. Brown, J. Finch, 1999, Journal of the American Society of Nephrology : JASN.

On the mechanisms for the selective action of vitamin D analogs.

T. Mori, A. Dusso, E. Slatopolsky, 1991, Endocrinology.

Selective vitamin D analogs and their therapeutic applications.

A. Dusso, E. Slatopolsky, A. Brown, 1994, Seminars in nephrology.

Combined effects of dexamethasone and 1,25-dihydroxyvitamin D3 on parathyroid hormone secretion in cultured bovine parathyroid cells.

E. Slatopolsky, J. Morrissey, T. Sugimoto, 1989, Endocrinology.

Decreased calcium-sensing receptor expression in hyperplastic parathyroid glands of uremic rats: role of dietary phosphate.

E. Slatopolsky, C. Ritter, A. Brown, 1999, Kidney international.

Cholesterol and desmosterol dancing to the beat of a different drug

I. Gelissen, A. Brown, A. J. Brown, 2018, Journal of internal medicine.

Hydrocortisone abolishes the angiotensin II-mediated potentiation of endothelin-1 in bovine bronchi.

A. Brown, J. Nally, 2001, Clinical science.

Inhibitors of fibrinolysis are elevated in atherosclerotic plaque.

B. Bennett, N. Booth, A. Brown, 1996, Arteriosclerosis, thrombosis, and vascular biology.

Role of phosphorus in the pathogenesis of secondary hyperparathyroidism.

A. Dusso, E. Slatopolsky, A. Brown, 2001, American journal of kidney diseases : the official journal of the National Kidney Foundation.

Regulation of renal vitamin D-24-hydroxylase by phosphate: effects of hypophysectomy, growth hormone and insulin-like growth factor I.

A. Brown, M. Grieff, S. Wu, 1997, Biochemical and biophysical research communications.

Retinoic acid suppresses parathyroid hormone (PTH) secretion and PreproPTH mRNA levels in bovine parathyroid cell culture.

E. Slatopolsky, P. N. MacDonald, C. Ritter, 1994, The Journal of clinical investigation.

The parathyroid-calcitriol axis in health and chronic renal failure.

J. Delmez, A. Dusso, K. Martin, 1990, Kidney international. Supplement.

Effects of sodium intake and aldosterone on the renal pressure-natriuresis.

S. Harrap, R. Fraser, A. Lever, 1988, The American journal of physiology.

New analogs of vitamin D3.

A. Dusso, E. Slatopolsky, A. Brown, 1999, Kidney international. Supplement.

Conformational studies of human plasminogen and plasminogen fragments: evidence for a novel third conformation of plasminogen.

C. Ponting, A. Brown, J. Marshall, 1994, Biochemistry.

The compact domain conformation of human Glu-plasminogen in solution.

C. Ponting, C. Blake, G. Spraggon, 1992, Biochimica et biophysica acta.

Calcemic activity of 19-Nor-1,25(OH)(2)D(2) decreases with duration of treatment.

E. Slatopolsky, A. Brown, J. Finch, 2000, Journal of the American Society of Nephrology : JASN.

Induction of the vitamin D 24-hydroxylase (CYP24) by 1,25-dihydroxyvitamin D3 is regulated by parathyroid hormone in UMR106 osteoblastic cells.

H. Armbrecht, T. Hodam, N. Partridge, 1998, Endocrinology.

Metabolism of 22-oxacalcitriol by a vitamin D-inducible pathway in cultured parathyroid cells.

E. Slatopolsky, M. Berkoben, C. Ritter, 1992, Biochemical and biophysical research communications.

Differential catabolism of 22-oxacalcitriol and 1,25-dihydroxyvitamin D3 by normal human peripheral monocytes.

A. Dusso, E. Slatopolsky, M. Gallieni, 1993, Endocrinology.

Batch-to-batch variation of Chelex-100 confounds metal-catalysed oxidation. Leaching of inhibitory compounds from a batch of Chelex-100 and their removal by a pre-washing procedure.

R. Dean, W. Jessup, D. van Reyk, 1995, Free radical research.

Differential effects of 1,25-(OH)2D3 and 22-oxacalcitriol on phosphate and calcium metabolism.

E. Slatopolsky, N. Kubodera, Y. Nishii, 1993, Kidney international.

The activity of 22-oxacalcitriol in osteoblast-like (ROS 17/2.8) cells.

T. Mori, E. Slatopolsky, Y. Nishii, 1991, Endocrinology.

Renal calcitriol synthesis and serum phosphorus in response to dietary phosphorus restriction and anabolic agents.

E. Slatopolsky, C. Ritter, M. Zhong, 1996, American journal of kidney diseases : the official journal of the National Kidney Foundation.

1,25-dihydroxyvitamin D3 and 22-oxacalcitriol prevent the decrease in vitamin D receptor content in the parathyroid glands of uremic rats.

E. Slatopolsky, N. Kubodera, Y. Nishii, 1996, Kidney international.

Metabolic clearance rate and production rate of calcitriol in uremia.

A. Dusso, E. Slatopolsky, K. Martin, 1989, Kidney international.

7-Hydroperoxycholesterol and its products in oxidized low density lipoprotein and human atherosclerotic plaque.

R. Dean, W. Jessup, A. Brown, 1997, Journal of lipid research.

The role of phosphorus in the development of secondary hyperparathyroidism and parathyroid cell proliferation in chronic renal failure.

A. Dusso, E. Slatopolsky, A. Brown, 1999, The American journal of the medical sciences.

Oxysterols and atherosclerosis.

Andrew J. Brown, W. Jessup, A J Brown, 1999, Atherosclerosis.

Pathogenesis of secondary hyperparathyroidism.

A. Dusso, E. Slatopolsky, A. Brown, 1994, Kidney international. Supplement.

Rat calcium-sensing receptor is regulated by vitamin D but not by calcium.

E. Slatopolsky, J. Morrissey, C. Ritter, 1996, The American journal of physiology.

Parathyroid hyperplasia in uremic rats precedes down-regulation of the calcium receptor.

E. Slatopolsky, C. Ritter, A. Brown, 2001, Kidney international.

The roles of calcium and 1,25-dihydroxyvitamin D3 in the regulation of vitamin D receptor expression by rat parathyroid glands.

E. Slatopolsky, C. Ritter, M. Zhong, 1995, Endocrinology.

p21(WAF1) and transforming growth factor-alpha mediate dietary phosphate regulation of parathyroid cell growth.

A. Dusso, E. Slatopolsky, J. Morrissey, 2001, Kidney international.

Effects of calcitriol and non-calcemic vitamin D analogs on secondary hyperparathyroidism.

J. Delmez, E. Slatopolsky, M. Berkoben, 1992, Kidney international. Supplement.

New active analogues of vitamin D with low calcemic activity.

A. Dusso, E. Slatopolsky, C. Ritter, 1990, Kidney international. Supplement.

Apolipoprotein J (clusterin) induces cholesterol export from macrophage-foam cells: a potential anti-atherogenic function?

R. Dean, I. Gelissen, M. Wilson, 1997, The Biochemical journal.

Alkyldihydroxyacetonephosphate synthase mechanism: 18O studies of fatty acid release from acyldihydroxyacetone phosphate.

F. Snyder, G. Glish, A. Brown, 1985, Biochemistry.

The mechanism of alkyldihydroxyacetone-P synthase. Formation of [3H]H2O from acyl[1-R-3H]dihydroxyacetone-P by purified alkyldihydroxyacetone-P synthase in the absence of acylhydrolase activity.

F. Snyder, A. Brown, 1983, The Journal of biological chemistry.

Alkyldihydroxyacetone-P synthase. Solubilization, partial purification, new assay method, and evidence for a ping-pong mechanism.

F. Snyder, A. Brown, 1982, The Journal of biological chemistry.

Solubilization of alkyldihydroxyacetone-P synthase from Ehrlich ascites cell microsomal membranes.

F. Snyder, A. Brown, 1979, Biochemical and biophysical research communications.

Hydroxypropyl-β-cyclodextrin-mediated Efflux of 7-Ketocholesterol from Macrophage Foam Cells*

R. Dean, Andrew J. Brown, L. Kritharides, 1996, The Journal of Biological Chemistry.

Extrarenal production of calcitriol.

J. Delmez, A. Dusso, E. Slatopolsky, 1990, Kidney international. Supplement.

Mechanisms for the selective actions of vitamin D analogues.

Alex J. Brown, A. Brown, A. Brown, 2000, Current pharmaceutical design.

Chronic angiotensin II infusion decreases renal norepinephrine overflow in conscious dogs.

T. Lohmeier, R. Carroll, A. Brown, 1984, Hypertension.

Intra-Operative Parathyroid Hormone Assay for Simplified Localization of Parathyroid Adenomas

A. Brown, M. Fahie-Wilson, M. Saharay, 1996, Journal of the Royal Society of Medicine.

Tocopherols and carotenes are differently distributed in subfractions of high-density lipoprotein.

Y. Fragoso, A. Brown, 1994, Biochimica et biophysica acta.

Malignant hypertensive crisis induced by chronic intrarenal norepinephrine infusion.

T. Lohmeier, R. Carroll, A. C. Guyton, 1984, Hypertension.

The noncalcemic analogue of vitamin D, 22-oxacalcitriol, suppresses parathyroid hormone synthesis and secretion.

E. Slatopolsky, J. Morrissey, K. Martin, 1989, The Journal of clinical investigation.

Renal osteodystrophy: past and future.

J. Delmez, A. Dusso, K. Martin, 1990, Contributions to Nephrology.

Pressor effects of brief and prolonged infusions of epinephrine in the conscious rat.

S. Ball, G. Murray, A. Lever, 1984, The American journal of physiology.

In vivo metabolism of alpha-tocopherol in lipoproteins and liver: studies on rabbits in response to acute cholesterol loading.

Y. Fragoso, A. Brown, 1998, Sao Paulo medical journal = Revista paulista de medicina.

Binding and metabolism of 1,25-dihydroxyvitamin D3 in cultured bovine parathyroid cells.

E. Slatopolsky, M. Berkoben, C. Ritter, 1992, Endocrinology.

Disparity between renal venous norepinephrine and renin responses to sodium depletion.

T. Lohmeier, R. Carroll, A. Brown, 1988, The American journal of physiology.

H-77: a potent new renin inhibitor. In vitro and in vivo studies

Dm Jones, M. Szelke, B. Leckie, 1982 .

Rapid haemodynamic response to adrenocorticotrophin and the role of peripheral resistance in adrenocorticotrophin-induced hypertension in conscious sheep.

J. Whitworth, D. Parkes, J. Coghlan, 1989, Journal of hypertension.

Effect of vitamin E on aortic lipid oxidation and intimal proliferation after arterial injury in cholesterol-fed rabbits.

J. Keaney, R. Stocker, P. Witting, 2001, Free radical biology & medicine.

Parathyroid hormone stimulation of the renal 25-hydroxyvitamin D-1α-hydroxylase—Effect of age and free radicals

H. Armbrecht, C. Ritter, A. Brown, 2007, The Journal of Steroid Biochemistry and Molecular Biology.

H-77: a potent new renin inhibitor. In vitro and in vivo studies.

M. Szelke, D. M. Jones, B. Leckie, 1982, Hypertension.

1,25-Dihydroxy-19-nor-vitamin D(2), a vitamin D analog with reduced bone resorbing activity in vitro.

E. Slatopolsky, L. Holliday, S. Gluck, 2000, Journal of the American Society of Nephrology : JASN.

Sterol 27-hydroxylase acts on 7-ketocholesterol in human atherosclerotic lesions and macrophages in culture.

G. Watts, R. Dean, J. Burnett, 2000, The Journal of biological chemistry.

Synthesis, stereochemistry, and biological activity of 1alpha,23,25-trihydroxy-24-oxovitamin D3, a major natural metabolite of 1alpha,25-dihydroxyvitamin D3.

P. Williard, G. Reddy, A. Brown, 1997, Biochemistry.

Expression of the renal 25-hydroxyvitamin D-24-hydroxylase gene: regulation by dietary phosphate.

E. Slatopolsky, M. Zhong, A. Brown, 1996, The American journal of physiology.

Slow rise and diurnal change of blood pressure with saralasin and angiotensin II in rats.

A. Lever, A. Brown, S. Clark, 1983, The American journal of physiology.