H. Tibbles

发表

Bruton's tyrosine kinase as a new therapeutic target.

F. Uckun, A. Vassilev, H. Tibbles, 2007, Anti-cancer agents in medicinal chemistry.

Brutons Tyrosine Kinase as a New Therapeutic Target

F. Uckun, A. Vassilev, H. Tibbles, 2007 .

The Anti-leukemic Bruto n's Tyrosine Kinase Inhibitor α-cyano-β-hydroxy-β-methyl-N-(2,5-dibromophenyl) Propenamide (LFM-A13) Prevents Fatal Thromboembolism

F. Uckun, S. Mahajan, S. Bartell, 2003 .

Blood brain barrier endothelial cells express candidate amyloid precursor protein-cleaving secretases.

D. Cribbs, C. Abraham, A. Billingslea, 1998, Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis.

Brain endothelial cell enzymes cleave platelet-retained amyloid precursor protein.

D. Cribbs, A. Billingslea, E. Simons, 1998, The Journal of laboratory and clinical medicine.

Platelets and DAMI megakaryocytes possess β-secretase-like activity

C. Abraham, A. Billingslea, E. Simons, 1999 .

Stimulus responses and amyloid precursor protein processing in DAMI megakaryocytes.

A. Billingslea, E. Simons, J. Schonhorn, 1997, The Journal of laboratory and clinical medicine.

Activated Alzheimer Disease Platelets Retain More Beta Amyloid Precursor Protein

A. Billingslea, E. Simons, J. Fishman, 1997, Neurobiology of Aging.

Anti-inflammatory activity profile of JANEX-1 in preclinical animal models.

F. Uckun, A. Vassilev, S. Qazi, 2008, Bioorganic & medicinal chemistry.

Thrombopoietin induces p-selectin expression on platelets and subsequent platelet/leukocyte interactions.

F. Uckun, A. Vassilev, M. Hupke, 2002, Biochemical and biophysical research communications.

SYK and LYN Mediate B-cell Receptor-independent Calcium-induced Apoptosis in DT-40 Lymphoma B-cells

F. Uckun, A. Vassilev, H. Tibbles, 2002, Leukemia & lymphoma.

CNS activity of Pokeweed Anti-viral Protein (PAP) in mice infected with Lymphocytic Choriomeningitis Virus (LCMV)

F. Uckun, A. Vassilev, H. Tibbles, 2005, BMC infectious diseases.

In vivo Pharmacokinetics and Toxicity Profile of the Anti-HIV Agent Stampidine in Dogs and Feline Immunodeficiency Virus-infected Cats

F. Uckun, B. Waurzyniak, T. Venkatachalam, 2006, Arzneimittelforschung.

Role of a JAK3-dependent Biochemical Signaling Pathway in Platelet Activation and Aggregation*

Dan Zhu, F. Uckun, A. Vassilev, 2001, The Journal of Biological Chemistry.

Stampidine prevents mortality in an experimental mouse model of viral hemorrhagic fever caused by lassa virus

F. Uckun, A. Vassilev, L. Titov, 2004, BMC infectious diseases.

In vivo pharmacokinetics, metabolism, toxicity, and anti-HIV activity of N'-[2-(2-Thiophene)ethyl]-N'-[2-(5-bromopyridyl)]thiourea (HI-443), a potent non-nucleoside inhibitor of HIV reverse transcriptase.

F. Uckun, T. Venkatachalam, H. Tibbles, 2011, Arzneimittel-Forschung.

In vivo Toxicity and Antithrombotic Profile of the Oral Formulation of the Antileukemic Agent, LFM-A13-F

F. Uckun, S. Mahajan, P. Samuel, 2004, Arzneimittelforschung.

Therapeutic potential of Janus kinase 3 (JAK3) inhibitors.

M. Cetkovic-Cvrlje, H. Tibbles, 2004, Current pharmaceutical design.

Erratum to: Stampidine prevents mortality in an experimental mouse model of viral hemorrhagic fever caused by lassa virus

F. Uckun, A. Vassilev, L. Titov, 2004, BMC infectious diseases.

Targeting JAK3 and BTK tyrosine kinases with rationally-designed inhibitors.

F. Uckun, A. Vassilev, T. Venkatachalam, 2006, Current drug targets.

The anti-leukemic Bruton's tyrosine kinase inhibitor alpha-cyano-beta-hydroxy-beta-methyl-N-(2,5-dibromophenyl) propenamide (LFM-A13) prevents fatal thromboembolism.

F. Uckun, S. Mahajan, S. Bartell, 2003, Leukemia & lymphoma.

A Dual Function Anti-leukemic Agent with Anti-thrombotic Activity

F. Uckun, A. Vassilev, H. Tibbles, 2002, Leukemia & lymphoma.

Hypermethylation of the spleen tyrosine kinase promoter in T-lineage acute lymphoblastic leukemia

F. Uckun, P. Goodman, B. Juran, 2003, Oncogene.

Role of the Leukemia-associated Transcription Factor STAT3 in Platelet Physiology

F. Uckun, A. Vassilev, H. Tibbles, 2002, Leukemia & lymphoma.

Platelets and DAMI megakaryocytes possess beta-secretase-like activity.

C. Abraham, A. Billingslea, E. Simons, 1999, The Journal of laboratory and clinical medicine.

Moderate and Advanced Alzheimer’s Patients Exhibit Platelet Activation Differences

R. Feldman, E. Simons, R. Fine, 1997, Neurobiology of Aging.

Stereochemistry as a Determinant of the Anti-Leukemic Potency of Halopyridyl and Thiazolyl Thiourea Compounds

F. Uckun, T. Venkatachalam, A. Vassilev, 2007 .

Anti-proliferative and anti-leukemic activity of DDE46 (compound WHI-07), a novel bromomethoxylated arylphosphate derivative of zidovudine, and related compounds. Studies using human acute lymphoblastic leukemia cells and the zebrafish model.

F. Uckun, A. Vassilev, S. Downs, 2005, Arzneimittel-Forschung.

Anti-Proliferative and Anti-Leukemic Activity of DDE46 (Compound WHI-07), a Novel Bromomethoxylated Arylphos-phate Derivative of Zidovudine, and Related Compounds

F. Uckun, A. Vassilev, S. Downs, 2005, Arzneimittelforschung.

Platelets from patients with Alzheimer's disease or other dementias exhibit disease-specific and apolipoprotein E correlatable defects

E. Simons, R. Fine, J. Wells, 1996 .

Targeting JAK3 tyrosine kinase-linked signal transduction pathways with rationally-designed inhibitors.

F. Uckun, A. Vassilev, I. Dibirdik, 2007, Anti-cancer agents in medicinal chemistry.