Mariah L. Arral

The replacement of helper lipids with charged alternatives in lipid nanoparticles facilities targeted mRNA delivery to the spleen and lungs.

K. Whitehead, S. LoPresti, Mariah L. Arral, 2022, Journal of controlled release : official journal of the Controlled Release Society.

Ionizable lipid nanoparticles deliver mRNA to pancreatic β cells via macrophage-mediated gene transfer

D. Weissman, K. Whitehead, M. Alameh, 2023, Science advances.

The mixing method used to formulate lipid nanoparticles affects mRNA delivery efficacy and organ tropism.

Mariah L. Arral, Namit Chaudhary, Daria M. Strelkova Petersen, 2023, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Placental drug transport and fetal exposure during pregnancy is determined by drug molecular size, chemistry, and conformation.

K. Whitehead, Alexandra N. Newby, Katherine C. Fein, 2023, Journal of controlled release : official journal of the Controlled Release Society.

Lipid nanoparticle structure and delivery route during pregnancy dictates mRNA potency, immunogenicity, and health in the mother and offspring

Y. Sadovsky, K. Whitehead, S. Yerneni, 2023, bioRxiv.

Lipid nanoparticle structure and delivery route during pregnancy dictate mRNA potency, immunogenicity, and maternal and fetal outcomes

Y. Sadovsky, S. Yerneni, Alexandra N. Newby, 2024, Proceedings of the National Academy of Sciences of the United States of America.

Lipid nanoparticle chemistry determines how nucleoside base modifications alter mRNA delivery.

Khalid A. Hajj, D. Weissman, Lukas Farbiak, 2021, Journal of controlled release : official journal of the Controlled Release Society.

Elucidating the Electrochemical Mechanism of NG-Hydroxy-L-arginine.

Christian A. Tooley, J. Halpern, Mariah L. Arral, 2020, Journal of the Electrochemical Society.