C. Voitenleitner

发表

E1 Protein of Bovine Papillomavirus Type 1 Interferes with E2 Protein-Mediated Tethering of the Viral DNA to Mitotic Chromosomes

M. Botchan, C. Voitenleitner, 2002, Journal of Virology.

Clinical and In Vitro Resistance to GS-9669, a Thumb Site II Nonnucleoside Inhibitor of the Hepatitis C Virus NS5B Polymerase

H. Mo, W. Delaney, H. Dvory‐Sobol, 2014, Antimicrobial Agents and Chemotherapy.

Discovery of a potent boronic acid derived inhibitor of the HCV RNA-dependent RNA polymerase.

R. Hamatake, Z. Hong, Shawn P. Williams, 2014, Journal of medicinal chemistry.

Woolly Monkey–HBV Infection in Squirrel Monkeys as a Surrogate Nonhuman Primate Model of HBV Infection

R. Lanford, E. Salas, W. Delaney, 2020, Hepatology communications.

In Vitro Characterization of GSK2485852, a Novel Hepatitis C Virus Polymerase Inhibitor

R. Hamatake, Z. Hong, J. Vamathevan, 2013, Antimicrobial Agents and Chemotherapy.

Hepatitis C genotype 1a replicon improved through introduction of fitness mutations.

R. Hamatake, J. Bechtel, A. Arfsten, 2012, BioTechniques.

Design of N-Benzoxaborole Benzofuran GSK8175—Optimization of Human Pharmacokinetics Inspired by Metabolites of a Failed Clinical HCV Inhibitor

D. J. Price, John Miller, Shawn P. Williams, 2019, Journal of medicinal chemistry.

764 IN VITRO PROFILING OF GSK2336805, A POTENT AND SELECTIVE INHIBITOR OF HCV NS5A

R. Hamatake, J. Vamathevan, W. Kazmierski, 2011 .

Species-specific replication of simian virus 40 DNA in vitro requires the p180 subunit of human DNA polymerase alpha-primase

H. Nasheuer, E. Fanning, C. Voitenleitner, 1996, Molecular and cellular biology.

Nucleotide Prodrug Containing a Nonproteinogenic Amino Acid To Improve Oral Delivery of a Hepatitis C Virus Treatment

Huiling Yang, M. Fenaux, Neeraj Tirunagari, 2018, Antimicrobial Agents and Chemotherapy.

Toll‐Like Receptor 8 Agonist GS‐9688 Induces Sustained Efficacy in the Woodchuck Model of Chronic Hepatitis B

R. Mackman, S. Balsitis, W. Delaney, 2020, Hepatology.

Cell-Free Hepatitis B Virus Capsid Assembly Dependent on the Core Protein C-Terminal Domain and Regulated by Phosphorylation

W. Delaney, Jianming Hu, Kuancheng Liu, 2016, Journal of Virology.

A randomized, double blind, dose escalation, first time in human study to assess the safety, tolerability, pharmacokinetics, and antiviral activity of single doses of GSK2485852 in chronically infected hepatitis C subjects

D. Wilfret, K. Adkison, A. Spaltenstein, 2014, Clinical pharmacology in drug development.

Spatiotemporal Analysis of Hepatitis B Virus X Protein in Primary Human Hepatocytes

S. Fletcher, D. Kornyeyev, H. Kwon, 2019, Journal of Virology.

Cell Cycle-Dependent Regulation of Human DNA Polymerase α-Primase Activity by Phosphorylation

H. Nasheuer, P. Liao, E. Fanning, 1999, Molecular and Cellular Biology.

Preclinical Characterization of GSK2336805, a Novel Inhibitor of Hepatitis C Virus Replication That Selects for Resistance in NS5A

R. Hamatake, J. Vamathevan, W. Kazmierski, 2013, Antimicrobial Agents and Chemotherapy.

Running title: Preclinical characterization of GSK2336805

R. Hamatake, J. Vamathevan, W. Kazmierski, 2013 .

Structure of the papillomavirus DNA-tethering complex E2:Brd4 and a peptide that ablates HPV chromosomal association.

M. Botchan, E. Abbate, Michael R Botchan, 2006, Molecular cell.

Phosphorylation of DNA polymerase α-primase by Cyclin A-dependent kinases regulates initiation of DNA replication in vitro

H. Nasheuer, E. Fanning, C. Voitenleitner, 1997, Oncogene.

P1224 GSK2878175, A POTENT NON-NUCLEOSIDE INHIBITOR OF HCV NS5B WITH PAN-GENOTYPIC ACTIVITY

R. Hamatake, Z. Hong, R. Crosby, 2014 .