P. Rajendran

发表

Cytoprotective role of astaxanthin against glycated protein/iron chelate‐induced toxicity in human umbilical vein endothelial cells

I. Nishigaki, Y. Nishigaki, D. Sakthisekaran, 2010, Phytotherapy research : PTR.

Exposure to polycyclic aromatic hydrocarbons with special focus on cancer

I. Nishigaki, P. Rajendran, T. Rengarajan, 2015 .

The Epidemiology of Human Breast Cancer

M. Balasubramanian, I. Nishigaki, P. Rajendran, 2014 .

Celastrol inhibits tumor cell proliferation and promotes apoptosis through the activation of c-Jun N-terminal kinase and suppression of PI3 K/Akt signaling pathways

G. Sethi, Feng Li, A. Kumar, 2011, Apoptosis.

Plumbagin inhibits invasion and migration of breast and gastric cancer cells by downregulating the expression of chemokine receptor CXCR4

G. Sethi, K. Ahn, Feng Li, 2011, Molecular Cancer.

Effects of polyphenols on ncRNAs in cancer—An update

U. Mony, E. Ahmed, Kaviyarasi Renu, 2022, Clinical and experimental pharmacology & physiology.

In vivo protective effect of crocetin on benzo(a)pyrene‐induced lung cancer in Swiss albino mice

D. Sakthisekaran, P. Rajendran, V. Magesh, 2009, Phytotherapy research : PTR.

The microRNA-202 as a Diagnostic Biomarker and a Potential Tumor Suppressor

H. Scherthan, E. Ahmed, P. Rajendran, 2022, International journal of molecular sciences.

Cancer Preventive Efficacy of Marine Carotenoid Fucoxanthin: Cell Cycle Arrest and Apoptosis

I. Nishigaki, P. Rajendran, T. Rengarajan, 2013, Nutrients.

Consumption of reused vegetable oil intensifies BRCA1 mutations

V. Veeraraghavan, P. Rajendran, T. Rengarajan, 2020, Critical reviews in food science and nutrition.

Effect of Extract of Pomegranate (Punica granatum L.) on Glycated Protein-iron Chelate-induced Toxicity: An In Vitro Study on Human Umbilical-vein Endothelial Cells

I. Nishigaki, Y. Nishigaki, D. Sakthisekaran, 2008 .

Tanshinone IIA Inhibits β-Catenin Nuclear Translocation and IGF-2R Activation via Estrogen Receptors to Suppress Angiotensin II-Induced H9c2 Cardiomyoblast Cell Apoptosis

Ray-Jade Chen, V. Viswanadha, Chih-Yang Huang, 2017, International journal of medical sciences.

Potent chemopreventive effect of mangiferin on lung carcinogenesis in experimental Swiss albino mice.

I. Nishigaki, D. Sakthisekaran, P. Rajendran, 2014, Journal of cancer research and therapeutics.

Early initiation of insulin attenuates histological and functional changes in the liver of streptozotocin-induced diabetic rats using 99mTc-sulfur colloid functional imaging

S. Al-Waheeb, P. Rajendran, K. Khan, 2021, Journal of receptor and signal transduction research.

Cardiac Protective Effect of Kirenol against Doxorubicin-Induced Cardiac Hypertrophy in H9c2 Cells through Nrf2 Signaling via PI3K/AKT Pathways

V. Veeraraghavan, Hamza Hanieh, P. Rajendran, 2021, International journal of molecular sciences.

Protective role of mangiferin against Benzo(a)pyrene induced lung carcinogenesis in experimental animals.

D. Sakthisekaran, P. Rajendran, G. Ekambaram, 2008, Biological & pharmaceutical bulletin.

Stimulatory Role of Glycated Fetal Bovine Serum Along with Iron on In Vitro Production of Insulin by Differentiated Mouse Embryonic Stem Cells

I. Nishigaki, Y. Nishigaki, D. Sakthisekaran, 2011 .

Immunomodulatory Effect of Mangiferin in Experimental Animals with Benzo(a)Pyrene-induced Lung Carcinogenesis

I. Nishigaki, Y. Nishigaki, D. Sakthisekaran, 2013, International journal of biomedical science : IJBS.

Tanshinone-induced ERs suppresses IGFII activation to alleviate Ang II-mediated cardiac hypertrophy

Ray-Jade Chen, W. Kuo, P. Pai, 2017, Journal of receptor and signal transduction research.

Identification of a Novel Calotropis procera Protein That Can Suppress Tumor Growth in Breast Cancer through the Suppression of NF-κB Pathway

G. Sethi, S. Ignacimuthu, V. Chow, 2012, PloS one.

Kaempferol Inhibits Zearalenone-Induced Oxidative Stress and Apoptosis via the PI3K/Akt-Mediated Nrf2 Signaling Pathway: In Vitro and In Vivo Studies

A. Soliman, M. Mohamed, P. Rajendran, 2020, International journal of molecular sciences.

Lactobacillus paracasei GMNL-32 exerts a therapeutic effect on cardiac abnormalities in NZB/W F1 mice

Ray-Jade Chen, B. Tzang, Tsung‐Jung Ho, 2017, PloS one.

Polyphenols as Potent Epigenetics Agents for Cancer

E. Ahmed, Kaviyarasi Renu, V. Veeraraghavan, 2022, International journal of molecular sciences.

Effect of fresh apple extract on glycated protein/iron chelate-induced toxicity in human umbilical vein endothelial cells in vitro

I. Nishigaki, B. Rajkapoor, Y. Nishigaki, 2010, Natural product research.

Ruscogenin Protects Against Deoxynivalenol-Induced Hepatic Injury by Inhibiting Oxidative Stress, Inflammation, and Apoptosis Through the Nrf2 Signaling Pathway: An In vitro Study

A. Sedky, Hany Elsawy, Manal A. Alfwuaires, 2022, Saudi journal of medicine & medical sciences.

Fucoxanthin suppresses OxLDL-induced inflammation via activation of Nrf2 and inhibition of NF-κB signaling

P. Rajendran, A. Alzahrani, 2022, Asian Pacific Journal of Tropical Biomedicine.

Anti-Apoptotic Effect of Flavokawain A on Ochratoxin-A-Induced Endothelial Cell Injury by Attenuation of Oxidative Stress via PI3K/AKT-Mediated Nrf2 Signaling Cascade

E. Ahmed, P. Rajendran, A. Alzahrani, 2021, Toxins.

Zerumbone Exhibit Protective Effect against Zearalenone Induced Toxicity via Ameliorating Inflammation and Oxidative Stress Induced Apoptosis

P. Rajendran, H. M. AbuZahra, Mohammad Bani Ismail, 2021, Antioxidants.

Kirenol Inhibits B[a]P-Induced Oxidative Stress and Apoptosis in Endothelial Cells via Modulation of the Nrf2 Signaling Pathway

E. Ahmed, V. Veeraraghavan, P. Rajendran, 2021, Oxidative medicine and cellular longevity.

Mangiferin Inhibits Apoptosis in Doxorubicin-Induced Vascular Endothelial Cells via the Nrf2 Signaling Pathway

V. Veeraraghavan, P. Rajendran, H. M. AbuZahra, 2021, International journal of molecular sciences.

Zerumbone protects human skin keratinocytes against UVA‐irradiated damages through Nrf2 induction

Mallikarjuna Korivi, Jia-jiuan Wu, Y. Hseu, 2018, Biochemical pharmacology.

Abrogation of STAT3 signaling cascade by zerumbone inhibits proliferation and induces apoptosis in renal cell carcinoma xenograft mouse model

G. Sethi, K. Ahn, Chulwon Kim, 2015, Molecular carcinogenesis.

Kaempferol, a Potential Cytostatic and Cure for Inflammatory Disorders

I. Nishigaki, Y. Nishigaki, P. Rajendran, 2014 .

Cytoprotective effect of mangiferin on benzo(a)pyrene-induced lung carcinogenesis in swiss albino mice.

D. Sakthisekaran, P. Rajendran, G. Ekambaram, 2008, Basic & clinical pharmacology & toxicology.

Editorial: Development of novel small molecules as therapeutics for inflammatory diseases and delineating their molecular mechanisms

T. Ramprasath, J. Gopas, S. Vaiyapuri, 2022, Frontiers in Pharmacology.

D-pinitol promotes apoptosis in MCF-7 cells via induction of p53 and Bax and inhibition of Bcl-2 and NF-κB.

M. Balasubramanian, I. Nishigaki, P. Rajendran, 2014, Asian Pacific journal of cancer prevention : APJCP.

Brassinin Enhances Apoptosis in Hepatic Carcinoma by Inducing Reactive Oxygen Species Production and Suppressing the JAK2/STAT3 Pathway

A. Sedky, Hany Elsawy, Manal A. Alfwuaires, 2022, Applied Sciences.

Investigation of the potential anti-urolithiatic activity of Alhagi maurorum (Boiss.) grown wild in Al-Ahsa (Eastern Province), Saudi Arabia.

P. Rajendran, R. Ammar, A. M. Hafez, 2022, Brazilian journal of biology = Revista brasleira de biologia.

Osteogenic differentiation and mineralization potential of zinc oxide nanoparticles from Scutellaria baicalensis on human osteoblast-like MG-63 cells.

A. Chinnathambi, S. Alharbi, Yanfeng Tang, 2021, Materials Science and Engineering C: Materials for Biological Applications.

Kaempferol, a potential cytostatic and cure for inflammatory disorders.

I. Nishigaki, Y. Nishigaki, P. Rajendran, 2014, European journal of medicinal chemistry.

Diosgenin, a steroidal saponin, inhibits STAT3 signaling pathway leading to suppression of proliferation and chemosensitization of human hepatocellular carcinoma cells.

G. Sethi, Feng Li, K. Hui, 2010, Cancer letters.

Combination therapeutic effect of cisplatin along with Solanum trilobatum on benzo(a)pyrene induced experimental lung carcinogenesis

D. Sakthisekaran, P. Rajendran, P. Venkatesan, 2008, Natural product research.

Effect of mangiferin on benzo(a)pyrene induced lung carcinogenesis in experimental Swiss albino mice

D. Sakthisekaran, P. Rajendran, G. Ekambaram, 2008, Natural product research.

Thymoquinone inhibits proliferation, induces apoptosis and chemosensitizes human multiple myeloma cells through suppression of signal transducer and activator of transcription 3 activation pathway

G. Sethi, Feng Li, P. Rajendran, 2010, British journal of pharmacology.

Potential Treatment of Dermatophyte Trichophyton rubrum in Rat Model Using Topical Green Biosynthesized Silver Nanoparticles with Achillea santolina Extract

B. Abdallah, E. Ali, P. Rajendran, 2023, Molecules.

Chemopreventive efficacy of mangiferin against benzo(a)pyrene induced lung carcinogenesis in experimental animals.

D. Sakthisekaran, P. Rajendran, G. Ekambaram, 2008, Environmental toxicology and pharmacology.

Antioxidants and human diseases.

J. Gopas, I. Nishigaki, P. Rajendran, 2014, Clinica chimica acta; international journal of clinical chemistry.

Anti-Inflammatory Activity of Geraniol Isolated from Lemon Grass on Ox-LDL-Stimulated Endothelial Cells by Upregulation of Heme Oxygenase-1 via PI3K/Akt and Nrf-2 Signaling Pathways

R. Ksouri, M. Mohamed, Ashokkumar Sekar, 2022, Nutrients.

d-pinitol mitigates tumor growth by modulating interleukins and hormones and induces apoptosis in rat breast carcinogenesis through inhibition of NF-κB

M. Balasubramanian, I. Nishigaki, P. Rajendran, 2015, Journal of Physiology and Biochemistry.

Impact of naringenin on glycoprotein levels in N-methyl-N′-nitro-N-nitrosoguanidine-induced gastric carcinogenesis in rats

D. Sakthisekaran, P. Rajendran, G. Ekambaram, 2008, Anti-cancer drugs.

The Multifarious Link between Cytochrome P450s and Cancer

P. Rajendran, A. Alzahrani, 2020, Oxidative medicine and cellular longevity.

In vitro studies on mangiferin protection against cadmium-induced human renal endothelial damage and cell death via the MAP kinase and NF-κB pathways

I. Nishigaki, Y. Nishigaki, P. Rajendran, 2016, Journal of receptor and signal transduction research.

Antrodia salmonea‐induced oxidative stress abrogates HER‐2 signaling cascade and enhanced apoptosis in ovarian carcinoma cells

Y. Hseu, Hsin-Ling Yang, P. Rajendran, 2018, Journal of cellular physiology.

Natural Product Research: Formerly Natural Product Letters

D. Sakthisekaran, P. Rajendran, G. Ekambaram, 2008 .

Naringenin reduces tumor size and weight lost in N-methyl-N'-nitro-N-nitrosoguanidine-induced gastric carcinogenesis in rats.

D. Sakthisekaran, V. Magesh, P. Rajendran, 2008, Nutrition research.

Mangiferin in cancer chemoprevention and treatment: pharmacokinetics and molecular targets

I. Nishigaki, P. Rajendran, T. Rengarajan, 2015, Journal of receptor and signal transduction research.

Antrodia camphorata inhibits epithelial‐to‐mesenchymal transition by targeting multiple pathways in triple‐negative breast cancers

Y. Hseu, Hsin-Ling Yang, Geng-Ruei Chang, 2018, Journal of cellular physiology.

γ‐Tocotrienol is a novel inhibitor of constitutive and inducible STAT3 signalling pathway in human hepatocellular carcinoma: potential role as an antiproliferative, pro‐apoptotic and chemosensitizing agent

G. Sethi, Feng Li, A. Kumar, 2011, British journal of pharmacology.

Honokiol inhibits signal transducer and activator of transcription‐3 signaling, proliferation, and survival of hepatocellular carcinoma cells via the protein tyrosine phosphatase SHP‐1

G. Sethi, K. Ahn, Feng Li, 2012, Journal of cellular physiology.

Suppression of Signal Transducer and Activator of Transcription 3 Activation by Butein Inhibits Growth of Human Hepatocellular Carcinoma In Vivo

Taher Abbasi, Shireen Vali, Gautam Sethi, 2010, Clinical Cancer Research.

Autophagy and senescence: A new insight in selected human diseases

Hamza Hanieh, M. A. Alhoot, P. Rajendran, 2019, Journal of cellular physiology.

Ursolic acid inhibits multiple cell survival pathways leading to suppression of growth of prostate cancer xenograft in nude mice

G. Sethi, Feng Li, A. Kumar, 2011, Journal of Molecular Medicine.

Butein downregulates chemokine receptor CXCR4 expression and function through suppression of NF-κB activation in breast and pancreatic tumor cells.

G. Sethi, E. Koay, Feng Li, 2010, Biochemical pharmacology.

Chalcone flavokawain A attenuates TGF‐β1‐induced fibrotic pathology via inhibition of ROS/Smad3 signaling pathways and induction of Nrf2/ARE‐mediated antioxidant genes in vascular smooth muscle cells

Y. Hseu, Hsin-Ling Yang, Ting-Yu Yang, 2018, Journal of cellular and molecular medicine.

Celastrol inhibits proliferation and induces chemosensitization through down‐regulation of NF‐κB and STAT3 regulated gene products in multiple myeloma cells

G. Sethi, Feng Li, A. Kumar, 2011, British journal of pharmacology.

The Vascular Endothelium and Human Diseases

Gautam Sethi, G. Sethi, I. Nishigaki, 2013, International journal of biological sciences.

Identification of β-Escin as a Novel Inhibitor of Signal Transducer and Activator of Transcription 3/Janus-Activated Kinase 2 Signaling Pathway that Suppresses Proliferation and Induces Apoptosis in Human Hepatocellular Carcinoma Cells

G. Sethi, Feng Li, A. Kumar, 2010, Journal of Pharmacology and Experimental Therapeutics.

The multifaceted link between inflammation and human diseases

Ray-Jade Chen, W. Kuo, V. Viswanadha, 2018, Journal of cellular physiology.

Antrodia salmonea suppresses invasion and metastasis in triple-negative breast cancer cells by reversing EMT through the NF-κB and Wnt/β-catenin signaling pathway.

Tzong-Der Way, Y. Hseu, Hsin-Ling Yang, 2019, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Thidiazuron decreases epithelial‐mesenchymal transition activity through the NF‐kB and PI3K/AKT signalling pathways in breast cancer

P. Rajendran, S. Al-Ramadan, R. Ben Ammar, 2020, Journal of cellular and molecular medicine.

Free radical scavenging and antioxidant activity of D-pinitol against 7, 12 dimethylbenz(a) anthracene induced breast cancer in sprague dawley rats

M. Balasubramanian, I. Nishigaki, P. Rajendran, 2014 .

Celastrol Suppresses Growth and Induces Apoptosis of Human Hepatocellular Carcinoma through the Modulation of STAT3/JAK2 Signaling Cascade In Vitro and In Vivo

J. Luk, G. Sethi, Feng Li, 2012, Cancer Prevention Research.

Inhibition of STAT3 dimerization and acetylation by garcinol suppresses the growth of human hepatocellular carcinoma in vitro and in vivo

J. Luk, G. Sethi, T. Kundu, 2014, Molecular Cancer.

G. Sethi, Feng Li, A. Kumar, 2010, Journal of Pharmacology and Experimental Therapeutics.

Petroleum Hydrocarbon and Living Organisms

P. Rajendran, A. Alzahrani, 2019, Hydrocarbon Pollution and its Effect on the Environment.

Polyphenols Mediate Neuroprotection in Cerebral Ischemic Stroke—An Update

Larance Ronsard, Kaviyarasi Renu, B. Abdallah, 2023, Nutrients.

Pinocembrin attenuates benzo(a)pyrene‐induced CYP1A1 expression through multiple pathways: An in vitro and in vivo study

P. Rajendran, A. Alzahrani, 2021, Journal of biochemical and molecular toxicology.

Benzo(a)Pyrene-Induced ROS-Mediated Lung Cancer

E. Ahmed, P. Rajendran, R. Ammar, 2022, Handbook of Oxidative Stress in Cancer: Mechanistic Aspects.

Benzo(a)Pyrene Induced ROS-Mediated Lung Cancer

E. Ahmed, P. Rajendran, R. Ammar, 2021, Handbook of Oxidative Stress in Cancer: Mechanistic Aspects.

Isoimperatorin therapeutic effect against aluminum induced neurotoxicity in albino mice

E. Ahmed, Duaa Althumairy, P. Rajendran, 2023, Frontiers in Pharmacology.

13-cis-Retinoic Acid Affects Brain Perfusion and Function: In Vivo Study

P. Rajendran, Fatma J Al-Saeedi, 2023, Molecular Imaging.

Diosgenin attenuates tumor growth and metastasis in transgenic prostate cancer mouse model by negatively regulating both NF-κB/STAT3 signaling cascades.

G. Sethi, K. Ahn, Jong Hyun Lee, 2021, European journal of pharmacology.

An anthraquinone derivative, emodin sensitizes hepatocellular carcinoma cells to TRAIL induced apoptosis through the induction of death receptors and downregulation of cell survival proteins

G. Sethi, K. Ahn, Joo-In Park, 2013, Apoptosis.

d-pinitol mitigates tumor growth by modulating interleukins and hormones and induces apoptosis in rat breast carcinogenesis through inhibition of NF-κB

M. Balasubramanian, I. Nishigaki, P. Rajendran, 2015, Journal of Physiology and Biochemistry.

An anthraquinone derivative, emodin sensitizes hepatocellular carcinoma cells to TRAIL induced apoptosis through the induction of death receptors and downregulation of cell survival proteins

G. Sethi, K. Ahn, Joo-In Park, 2013, Apoptosis.

Salivaomics to decode non-coding RNAs in oral cancer. A narrative review.

R. Prabhu, Selvaraj Jayaraman, V. Veeraraghavan, 2023, Non-coding RNA research.

Potential inhibitory effect of geraniol isolated from lemongrass (Cymbopogon commutatus Stapf) on tilmicosin-induced oxidative stress in cardiac tissue.

Manal A. Alfwuaires, P. Rajendran, R. Ben Ammar, 2023, Natural product research.

The effect of COVID-19 on nuclear medicine and radiopharmacy activities: A global survey

D. Tipre, P. Rajendran, Abdullah Alkhamis, 2023, Scientific reports.

Immunomodulatory Effect of Mangiferin in Experimental Animals with Benzo(a)Pyrene-induced Lung Carcinogenesis

I. Nishigaki, Y. Nishigaki, D. Sakthisekaran, 2013, International journal of biomedical science : IJBS.

Tanshinone-induced ERs suppresses IGFII activation to alleviate Ang II-mediated cardiac hypertrophy

Ray-Jade Chen, W. Kuo, P. Pai, 2017, Journal of receptor and signal transduction research.

Epigenetic modulation of long noncoding RNA H19 in oral squamous cell carcinoma-A narrative review

B. Abdallah, P. Rajendran, Vishnupriya Veeraraghavan, 2024, Non-coding RNA Research.

Unveiling the power of flavonoids: A dynamic exploration of their impact on cancer through matrix metalloproteinases regulation

P. Rajendran, 2024, BioMedicine.

Nimbolide: promising agent for prevention and treatment of chronic diseases (recent update)

Kaviyarasi Renu, B. Abdallah, V. Veeraraghavan, 2024, Food & nutrition research.

dimethylbenz(a) anthracene induced breast cancer in sprague dawley rats

Balasubramanian, I. Nishigaki, P. Rajendran, 2014 .

Cytoprotective role of astaxanthin against glycated protein/iron chelate‐induced toxicity in human umbilical vein endothelial cells

I. Nishigaki, Y. Nishigaki, D. Sakthisekaran, 2010, Phytotherapy research : PTR.

PI3K/AKT Signaling Pathway Mediated Autophagy in Oral Carcinoma - A Comprehensive Review

B. Abdallah, P. Rajendran, S. Abdelsalam, 2024, International journal of medical sciences.

Abrogation of STAT3 signaling cascade by zerumbone inhibits proliferation and induces apoptosis in renal cell carcinoma xenograft mouse model

G. Sethi, K. Ahn, Chulwon Kim, 2015, Molecular carcinogenesis.

The Inhibitory Effect of Geraniol on CCL4-induced Hepatorenal Toxicity in Pregnant Mice through the PI3K/AKT Signaling Pathway

B. Abdallah, P. Rajendran, G. Bekhet, 2024, Saudi journal of medicine & medical sciences.