A. Yasuhara

发表

IN VITRO AND IN VIVO EVALUATION OF THE METABOLISM AND BIOAVAILABILITY OF ESTER PRODRUGS OF MGS0039 (3-(3,4-DICHLOROBENZYLOXY)-2-AMINO-6-FLUOROBICYCLO[3.1.0]HEXANE-2,6-DICARBOXYLIC ACID), A POTENT METABOTROPIC GLUTAMATE RECEPTOR ANTAGONIST

A. Nakazato, Masato Nakamura, Y. Kawakita, 2006, Drug Metabolism and Disposition.

Convenient synthesis of 2-substituted indoles from 2-ethynylanilines with tetrabutylammonium fluoride

A. Numata, M. Kaneko, Y. Kondo, 1999 .

ELECTROCHEMICAL GENERATION OF HIGHLY REACTIVE NICKEL AND ITS UTILIZATION FOR THE DEHALOGENATIVE COUPLING OF ARYL HALIDES

T. Sakamoto, A. Yasuhara, and Atsushi Kasano, 1998 .

Identification of 1-Methyl-N-(propan-2-yl)-N-({2-[4-(trifluoromethoxy)phenyl]pyridin-4-yl}methyl)-1H-imidazole-4-carboxamide as a Potent and Orally Available Glycine Transporter 1 Inhibitor.

M. Moriya, H. Ohta, Y. Kawakita, 2016, Chemical & pharmaceutical bulletin.

JPET #218651 1 Neurophysiological and Antipsychotic Profiles of TASP0433864, a Novel Positive Allosteric Modulator of Metabotropic Glutamate 2 Receptor

S. Chaki, H. Hikichi, J. Karasawa, 2014 .

Novel synthetic strategy of carbolines via palladium-catalyzed amination and arylation reaction

T. Sakamoto, A. Yasuhara, Takehiko Iwaki, 1999 .

Condensed Heteroaromatic Ring Systems. XX. Palladium-Catalyzed Carbonylative Coupling of Iodobenzenes with (Z)-1-Ethoxy-2-(tributylstannyl)ethene

Y. Kondo, T. Sakamoto, H. Yamanaka, 1992 .

Condensed heteroaromatic ring systems. XVIII. Palladium-catalyzed cross-coupling reaction of aryl bromides with (Z)-1-ethoxy-2-tributylstannylethene and its utilization for construction of condensed heteroaromatics

Y. Kondo, T. Sakamoto, H. Yamanaka, 1991 .

Cyclization reactions of 2-alkynylbenzyl alcohol and 2-alkynylbenzylamine derivatives promoted by tetrabutylammonium fluoride

Mitsuyoshi Kameda, K. Hiroya, T. Sakamoto, 2001 .

Selective Monodesulfonylation of N,N-Disulfonylarylamines with Tetrabutylammonium Fluoride

Mitsuyoshi Kameda, T. Sakamoto, A. Yasuhara, 1999 .

An Efficient Method for the Deallylation of Allyl Aryl Ethers Using Electrochemically Generated Nickel

T. Sakamoto, A. Yasuhara, and Atsushi Kasano, 1999 .

Convenient Reduction of Nitrobenzenes to Anilines Using Electrochemically Generated Nickel

T. Sakamoto, A. Yasuhara, and Atsushi Kasano, 1999 .

Total syntheses of three natural products, vignafuran, 2-(4-hydroxy-2-methoxyphenyl)-6-methoxybenzofuran-3-carboxylic acid methyl ester, and coumestrol from a common starting material

Yuya Egawa, K. Hiroya, T. Sakamoto, 2000 .

Convenient indole synthesis from ethynylanilines with a polymer-supported fluoride

T. Yoshino, T. Sakamoto, A. Yasuhara, 2002 .

Convenient indole synthesis from 2-iodoanilines and terminal alkynes by the sequential Sonogashira reaction and the cyclization reaction promoted by tetrabutylammonium fluoride (TBAF).

T. Sakamoto, A. Yasuhara, Naoyuki Suzuki, 2003, Chemical & pharmaceutical bulletin.

Synthesis of 2,3-disubstituted indole using palladium(II)-catalyzed cyclization with alkenylation reaction.

T. Sakamoto, A. Yasuhara, Naoyuki Suzuki, 2002, Chemical & pharmaceutical bulletin.

Synthesis of 2-Substituted 3-Alkenyl-indoles by the Palladium-catalyzed Cyclization Followed by Alkenylation (Heck Reaction)

M. Kaneko, T. Sakamoto, A. Yasuhara, 1998 .

A concise synthesis of furostifoline by tetrabutylammonium fluoride-promoted indole ring formation.

T. Sakamoto, A. Yasuhara, Naoyuki Suzuki, 2002, Chemical & pharmaceutical bulletin.

MGS0039: a potent and selective group II metabotropic glutamate receptor antagonist with antidepressant-like activity

S. Nakanishi, S. Chaki, R. Yoshikawa, 2004, Neuropharmacology.

An Efficient Method for the Deallylation of Allyl Aryl Ethers Using Electrochemically Generated Nickel.

T. Sakamoto, A. Yasuhara, and Atsushi Kasano, 1999 .

Convenient Reduction of Nitrobenzenes to Anilines Using Electrochemically Generated Nickel.

T. Sakamoto, A. Yasuhara, and Atsushi Kasano, 1999 .

Deprotection of N-sulfonyl nitrogen-heteroaromatics with tetrabutylammonium fluoride

T. Sakamoto, A. Yasuhara, T. Sakamoto*, 1998 .

Synthesis, in vitro pharmacology, and structure-activity relationships of 2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid derivatives as mGluR2 antagonists.

S. Chaki, R. Yoshikawa, A. Nakazato, 2006, Bioorganic & medicinal chemistry.

Preparation of ethyl arylpropiolates from aryl iodides by palladium-catalyzed cross-coupling reaction

Y. Kondo, F. Shiga, T. Sakamoto, 1992 .

Condensed Heteroaromatic Ring Systems. XXIII. A Concise Synthesis of Hippadine

Y. Kondo, T. Sakamoto, H. Yamanaka, 1993 .

Metabotropic Glutamate Receptors: Potential Drug Targets for Psychiatric Disorders

S. Chaki, A. Yasuhara, 2010, The open medicinal chemistry journal.

Neuropharmacological profiles of antagonists of group II metabotropic glutamate receptors

S. Chaki, S. Okuyama, A. Nakazato, 2005, Neuroscience Letters.

Antipsychotic profiles of TASP0443294, a novel and orally active positive allosteric modulator of metabotropic glutamate 2 receptor.

S. Chaki, H. Hikichi, J. Karasawa, 2015, Journal of pharmacological sciences.

Neurophysiologic and Antipsychotic Profiles of TASP0433864, a Novel Positive Allosteric Modulator of Metabotropic Glutamate 2 Receptor

S. Chaki, H. Hikichi, J. Karasawa, 2014, The Journal of Pharmacology and Experimental Therapeutics.

Convenient Synthesis of 2-Substituted Indoles from 2-Ethynylanilines with Tetrabutylammonium Fluoride.

A. Numata, M. Kaneko, Y. Kondo, 1999 .

Prodrugs of 3-(3,4-dichlorobenzyloxy)-2-amino-6-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic acid (MGS0039): a potent and orally active group II mGluR antagonist with antidepressant-like potential.

S. Chaki, R. Yoshikawa, A. Nakazato, 2006, Bioorganic & medicinal chemistry.

Synthesis, in vitro pharmacology, structure-activity relationships, and pharmacokinetics of 3-alkoxy-2-amino-6-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic acid derivatives as potent and selective group II metabotropic glutamate receptor antagonists.

S. Chaki, R. Yoshikawa, A. Nakazato, 2004, Journal of medicinal chemistry.

Synthesis, in vitro pharmacology, and pharmacokinetic profiles of 2-[1-amino-1-carboxy-2-(9H-xanthen-9-yl)-ethyl]-1-fluorocyclopropanecarboxylic acid and its 6-heptyl ester, a potent mGluR2 antagonist.

S. Chaki, R. Yoshikawa, A. Nakazato, 2008, Bioorganic & medicinal chemistry.

Deprotection of N‐Sulfonyl Nitrogen‐Heteroaromatics with Tetrabutylammonium Fluoride.

A. Yasuhara, T. Sakamoto*, 1998 .