G. Lesage

发表

Heterogeneity of the proliferative capacity of rat cholangiocytes after bile duct ligation.

N. LaRusso, S. Glaser, G. Alpini, 1998, American journal of physiology. Gastrointestinal and liver physiology.

Heterogeneity of the proliferative capacity of rat cholangiocytes after bile duct ligation.

N. LaRusso, S. Glaser, Y. Ueno, 1998, The American journal of physiology.

Regulation of cholangiocyte proliferation.

S. Glaser, G. Alpini, G. Lesage, 2001, Liver.

Recruited metastasis suppressor NM23-H2 attenuates expression and activity of peroxisome proliferator-activated receptor δ (PPARδ) in human cholangiocarcinoma.

P. Webb, L. Qin, X. Xia, 2015, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.

Degradation of the Apical Sodium-dependent Bile Acid Transporter by the Ubiquitin-Proteasome Pathway in Cholangiocytes*

X. Xia, S. Shentu, X. Lu, 2004, Journal of Biological Chemistry.

Acute carbon tetrachloride feeding induces damage of large but not small cholangiocytes from BDL rat liver.

S. Glaser, G. Alpini, A. Benedetti, 1999, American journal of physiology. Gastrointestinal and liver physiology.

Insulin inhibits secretin‐induced ductal secretion by activation of PKC alpha and inhibition of PKA activity

T. Patel, S. Glaser, G. Alpini, 2002, Hepatology.

Chronic Morphine-Induced MicroRNA-124 Promotes Microglial Immunosuppression by Modulating P65 and TRAF6

Yi Li, Ying Zhang, D. Yin, 2015, The Journal of Immunology.

Stimulation of α2‐adrenergic receptor inhibits cholangiocarcinoma growth through modulation of Raf‐1 and B‐Raf activities

S. Glaser, G. Alpini, H. Francis, 2002 .

The Role of Toll-Like Receptor 9 in Chronic Stress-Induced Apoptosis in Macrophage

D. Yin, G. Hanley, Jun Zhou, 2015, PloS one.

Gastrin inhibits cholangiocarcinoma growth through increased apoptosis by activation of Ca2+-dependent protein kinase C-alpha.

S. Glaser, G. Alpini, L. Baiocchi, 2001, Journal of hepatology.

Functional expression of the apical Na+-dependent bile acid transporter in large but not small rat cholangiocytes.

S. Glaser, G. Alpini, J. L. Phinizy, 1997, Gastroenterology.

Faculty Opinions recommendation of Opposing effects of retinoic acid on cell growth result from alternate activation of two different nuclear receptors.

G. Lesage, 2008 .

Acute carbon tetrachloride feeding selectively damages large, but not small, cholangiocytes from normal rat liver

S. Glaser, A. Benedetti, L. Baiocchi, 1999, Hepatology.

Tauroursodeoxycholate inhibits human cholangiocarcinoma growth via Ca2+-, PKC-, and MAPK-dependent pathways.

S. Glaser, G. Alpini, H. Francis, 2004, American journal of physiology. Gastrointestinal and liver physiology.

Liver X receptor β and peroxisome proliferator‐activated receptor δ regulate cholesterol transport in murine cholangiocytes

J. Gustafsson, D. Moore, P. Webb, 2012, Hepatology.

Bile acid interactions with cholangiocytes.

S. Glaser, G. Alpini, H. Francis, 2006, World journal of gastroenterology.

Cyclic AMP regulates bicarbonate secretion in cholangiocytes through release of ATP into bile.

D. A. Gomes, N. LaRusso, A. Masyuk, 2007, Gastroenterology.

HIV-1 gp120 primes lymphocytes for opioid-induced, beta-arrestin 2-dependent apoptosis.

Yangchao Chen, J. Moorman, D. Yin, 2009, Biochimica et biophysica acta.

β-arrestin 2 attenuates cardiac dysfunction in polymicrobial sepsis through gp130 and p38

Christopher R. Daniels, D. Yin, R. Hamdy, 2016, Biochemistry and biophysics reports.

Taurohyodeoxycholate- and tauroursodeoxycholate-induced hypercholeresis is augmented in bile duct ligated rats.

S. Glaser, G. Alpini, D. Alvaro, 2003, Journal of hepatology.

FXR-induced secretion of FGF15/19 inhibits CYP27 expression in cholangiocytes through p38 kinase pathway

D. Moore, P. Webb, G. Alpini, 2013, Pflügers Archiv - European Journal of Physiology.

Bile acids stimulate proliferative and secretory events in large but not small cholangiocytes.

S. Glaser, G. Alpini, J. L. Phinizy, 1997, The American journal of physiology.

Synthetic resveratrol aliphatic acid inhibits TLR2-mediated apoptosis and an involvement of Akt/GSK3beta pathway.

D. Yin, Xiuli Sun, Yi Zhang, 2009, Bioorganic & medicinal chemistry.

Hemochromatosis: genetic or alcohol-induced?

H. Gordon, S. Moore, A. H. Baggenstoss, 1983, Gastroenterology.

Development and characterization of secretin-stimulated secretion of cultured rat cholangiocytes.

S. Glaser, G. Alpini, A. Benedetti, 2003, American journal of physiology. Gastrointestinal and liver physiology.

Taurocholate prevents the loss of intrahepatic bile ducts due to vagotomy in bile duct-ligated rats.

T. Patel, C. Marienfeld, S. Glaser, 2003, American journal of physiology. Gastrointestinal and liver physiology.

Hemochromatosis: genetic or alcohol-induced?

H. Gordon, S. Moore, A. H. Baggenstoss, 1983, Gastroenterology.

Taurocholate feeding prevents CCl4-induced damage of large cholangiocytes through PI3-kinase-dependent mechanism.

S. Glaser, J. Venter, G. Alpini, 2003, American journal of physiology. Gastrointestinal and liver physiology.

Regression of cholangiocyte proliferation after cessation of ANIT feeding is coupled with increased apoptosis.

S. Glaser, G. Alpini, Y. Ueno, 2001, American journal of physiology. Gastrointestinal and liver physiology.

Increased susceptibility of cholangiocytes to tumor necrosis factor-alpha cytotoxicity after bile duct ligation.

T. Patel, S. Glaser, G. Alpini, 2003, American journal of physiology. Cell physiology.

Functional heterogeneity of cholangiocytes.

S. Glaser, G. Alpini, M. Marzioni, 2002, Seminars in liver disease.

Ursodeoxycholate and tauroursodeoxycholate inhibit cholangiocyte growth and secretion of BDL rats through activation of PKC alpha

S. Glaser, G. Alpini, Y. Ueno, 2002, Hepatology.

The α2-adrenergic receptor agonist UK 14,304 inhibits secretin-stimulated ductal secretion by downregulation of the cAMP system in bile duct-ligated rats

S. Glaser, J. Venter, G. Alpini, 2007 .

The alpha2-adrenergic receptor agonist UK 14,304 inhibits secretin-stimulated ductal secretion by downregulation of the cAMP system in bile duct-ligated rats.

S. Glaser, J. Venter, G. Alpini, 2007, American journal of physiology. Cell physiology.

α‐1 adrenergic receptor agonists modulate ductal secretion of BDL rats via Ca2+‐ and PKC‐dependent stimulation of cAMP

T. Roskams, S. Glaser, G. Alpini, 2004, Hepatology.

cAMP stimulates the secretory and proliferative capacity of the rat intrahepatic biliary epithelium through changes in the PKA/Src/MEK/ERK1/2 pathway.

S. Glaser, J. Venter, G. Alpini, 2004, Journal of hepatology.

Functional heterogeneity of the intrahepatic biliary epithelium

S. Glaser, D. Alvaro, G. Alpini, 2000, Hepatology.

Gastrin inhibits secretin-induced ductal secretion by interaction with specific receptors on rat cholangiocytes.

S. Glaser, G. Alpini, J. L. Phinizy, 1997, American journal of physiology. Gastrointestinal and liver physiology.

Large but not small intrahepatic bile ducts are involved in secretin-regulated ductal bile secretion.

S. Glaser, J. L. Phinizy, G. Lesage, 1997, The American journal of physiology.

β-Arrestin 2 Promotes Hepatocyte Apoptosis by Inhibiting Akt Protein*

D. Yin, H. Fan, Zhongmin Liu, 2015, The Journal of Biological Chemistry.

promoter-reporter transgene

Wenzheng Zhang, B. Kone, Xuefeng Xia, 2004 .

Bile acid depletion and repletion regulate cholangiocyte growth and secretion by a phosphatidylinositol 3-kinase-dependent pathway in rats.

S. Glaser, G. Alpini, Y. Ueno, 2002, Gastroenterology.

Cholinergic system modulates growth, apoptosis, and secretion of cholangiocytes from bile duct-ligated rats.

S. Glaser, G. Alpini, A. Benedetti, 1999, Gastroenterology.

Regrowth of the rat biliary tree after 70% partial hepatectomy is coupled to increased secretin-induced ductal secretion.

S. Glaser, G. Alpini, J. L. Phinizy, 1996, Gastroenterology.

Faculty Opinions recommendation of Dok1 mediates high-fat diet-induced adipocyte hypertrophy and obesity through modulation of PPAR-gamma phosphorylation.

G. Lesage, 2008 .

2. FUNCTIONAL HETEROGENEITY OF INTRAHEPATIC CHOLANGIOCYTES

S. Glaser, G. Alpini, H. Francis, 2004 .

The Pathobiology of Cholangiocytes

S. Glaser, G. Alpini, M. Marzioni, 2004 .

Regulation of cholangiocyte bicarbonate secretion.

S. Glaser, G. Alpini, N. Kanno, 2001, American journal of physiology. Gastrointestinal and liver physiology.

Regulatory mechanisms of ductal bile secretion.

S. Glaser, G. Lesage, G. Alpini, 2000, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.

Regulation of cholangiocyte bile secretion.

S. Glaser, L. Baiocchi, G. Lesage, 1999, Journal of hepatology.

gamma-Interferon inhibits secretin-induced choleresis and cholangiocyte proliferation in a murine model of cirrhosis.

S. Glaser, J. L. Phinizy, G. Lesage, 1997, Journal of hepatology.

Gastrin inhibits secretin-induced ductal secretion by interaction with specific receptors on rat cholangiocytes.

S. Glaser, J. L. Phinizy, A. Caligiuri, 1997, The American journal of physiology.

Secretin activation of the apical Na+‐dependent bile acid transporter is associated with cholehepatic shunting in rats

S. Glaser, G. Alpini, L. Baiocchi, 2005, Hepatology.

Gastrin reverses established cholangiocyte proliferation and enhanced secretin‐stimulated ductal secretion of BDL rats by activation of apoptosis through increased expression of Ca2+‐dependent PKC isoforms

S. Glaser, J. Venter, G. Alpini, 2003, Liver international : official journal of the International Association for the Study of the Liver.

Gastrin inhibits cholangiocyte growth in bile duct–ligated rats by interaction with cholecystokinin‐B/gastrin receptors via D ‐myo‐inositol 1,4,5‐triphosphate–, Ca2+‐, and protein kinase C α–dependent mechanisms

S. Glaser, G. Alpini, A. Benedetti, 2000 .

Bile acid feeding induces cholangiocyte proliferation and secretion: evidence for bile acid-regulated ductal secretion.

S. Glaser, G. Alpini, Y. Ueno, 1999, Gastroenterology.

Critical Role of Toll-Like Receptor 9 in Morphine and Mycobacterium tuberculosis–Induced Apoptosis in Mice

W. Shi, Ying Zhang, D. Yin, 2010, PloS one.

Toll-like receptor 2 is required for opioids-induced neuronal apoptosis.

Ying Zhang, D. Yin, Yi Li, 2010, Biochemical and biophysical research communications.

Essential role of toll-like receptor 2 in morphine-induced microglia activation in mice

D. Yin, Yi Li, Xiuli Sun, 2011, Neuroscience Letters.

Acute carbon tetrachloride feeding induces damage of large but not small cholangiocytes from BDL rat liver.

S. Glaser, G. Alpini, L. Holcomb, 1999, The American journal of physiology.

Hepatic Artery Mycotic Aneurysm Associated with Staphylococcal Endocarditis with Successful Treatment: Case Report with Review of the Literature

A. Saleem, D. Chaudhari, M. Young, 2013, Case reports in hepatology.

Autocrine/paracrine regulation of the growth of the biliary tree by the neuroendocrine hormone serotonin.

T. Roskams, S. Glaser, J. Venter, 2005, Gastroenterology.

Biliary excretion of iron from hepatocyte lysosomes in the rat. A major excretory pathway in experimental iron overload.

N. LaRusso, L. Kost, S. Barham, 1986, The Journal of clinical investigation.

Glycogen synthase kinase-3 and p38 MAPK are required for opioid-induced microglia apoptosis

Z. Chi, D. Yin, N. Xie, 2010, Neuropharmacology.

Evaluation of differential gene expression by microarray analysis in small and large cholangiocytes isolated from normal mice

T. Shimosegawa, S. Glaser, G. Alpini, 2003, Liver international : official journal of the International Association for the Study of the Liver.

Chronic stress promotes lymphocyte reduction through TLR2 mediated PI3K signaling in a β-arrestin 2 dependent manner

D. Yin, Yi Zhang, G. Hanley, 2011, Journal of Neuroimmunology.

Heterogeneity of the intrahepatic biliary epithelium.

S. Glaser, J. Venter, G. Alpini, 2006, World journal of gastroenterology.

Bile acid feeding increased proliferative activity and apical bile acid transporter expression in both small and large rat cholangiocytes

S. Glaser, G. Alpini, Y. Ueno, 2001, Hepatology.

Cholangiocyte injury and ductopenic syndromes.

S. Glaser, G. Alpini, M. Marzioni, 2007, Seminars in liver disease.

Molecular and functional heterogeneity of cholangiocytes from rat liver after bile duct ligation.

N. LaRusso, L. Miller, Y. Ueno, 1997, The American journal of physiology.

Bile acid-dependent vesicular transport of lysosomal enzymes into bile in the rat.

M. A. Baumgart, G. Lesage, W. Robertson, 1993, Gastroenterology.

Role of apoptosis in development of primary biliary cirrhosis.

S. Glaser, G. Alpini, M. Marzioni, 2001, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.

Expression of GCIP in transgenic mice decreases susceptibility to chemical hepatocarcinogenesis

F. Wang, W. Ma, C. Yu, 2006, Oncogene.

In vivo expression profile of a H+-K+-ATPase alpha2-subunit promoter-reporter transgene.

Wenzheng Zhang, B. Kone, G. Lesage, 2004, American journal of physiology. Renal physiology.

Microscopic Colitis with Macroscopic Endoscopic Findings

A. Saleem, Sarah Khan, M. Young, 2013, Case reports in medicine.

Case Report Microscopic Colitis with Macroscopic Endoscopic Findings 1. Case Report

A. Saleem, Sarah Khan, M. Young, 2022 .

Aldosterone-sensitive repression of ENaCalpha transcription by a histone H3 lysine-79 methyltransferase.

Wenzheng Zhang, William Xu, B. Kone, 2006, American journal of physiology. Cell physiology.

Immunologic and virologic status of multitransfused patients: role of type and origin of blood products. By the AIDS-Hemophilia French Study Group.

A. Goudeau, C. Guérois, Y. Laurian, 1985, Blood.