T. Laitala-Leinonen

发表

Receptor tyrosine kinase inhibition causes simultaneous bone loss and excess bone formation within growing bone in rats.

J. Toppari, K. Jahnukainen, J. Määttä, 2011, Toxicology and applied pharmacology.

Downregulation of Small GTPase Rab7 Impairs Osteoclast Polarization and Bone Resorption* 210

V. Parikka, H. Väänänen, Haibo Zhao, 2001, The Journal of Biological Chemistry.

Unsatisfactory gene transfer into bone-resorbing osteoclasts with liposomal transfection systems

T. Laitala-Leinonen, 2005, Journal of Negative Results in BioMedicine.

The regulation of pHi in osteoclasts is dependent on the culture substrate and on the stage of the resorption cycle.

P. Lehenkari, H. Väänänen, T. Linna, 1997, Biochemical and biophysical research communications.

Impaired osteoclast homeostasis in the cystatin B-deficient mouse model of progressive myoclonus epilepsy

R. Kiviranta, A. Kallonen, A. Lehesjoki, 2015, Bone reports.

Inhibition of intravacuolar acidification by antisense RNA decreases osteoclast differentiation and bone resorption in vitro.

C. Löwik, H. Väänänen, S. Papapoulos, 1999, Journal of cell science.

Overexpression of cathepsin K accelerates the resorption cycle and osteoblast differentiation in vitro.

E. Vuorio, R. Kiviranta, H. Väänänen, 2009, Bone.

Inhibition of the osteoclast V‐ATPase by small interfering RNAs

Yingwei Hu, Pirkko Muhonen, H. Väänänen, 2005, FEBS letters.

Recombinant VSV G proteins reveal a novel raft-dependent endocytic pathway in resorbing osteoclasts.

Yi Sun, K. Metsikkö, H. Väänänen, 2008, Experimental cell research.

Sequence and TLR9 independent increase of TRACP expression by antisense DNA and siRNA molecules.

S. Avnet, Pirkko Muhonen, H. Väänänen, 2007, Biochemical and biophysical research communications.

Cystatin B as an intracellular modulator of bone resorption.

A. Rinne, P. Saukko, R. Rinne, 2006, Matrix biology : journal of the International Society for Matrix Biology.

Carbonic anhydrase II plays a major role in osteoclast differentiation and bone resorption by effecting the steady state intracellular pH and Ca2+.

P. Lehenkari, J. Tuukkanen, T. Hentunen, 1998, Experimental cell research.

Synthesis of multi-galactose-conjugated 2'-O-methyl oligoribonucleotides and their in vivo imaging with positron emission tomography.

H. Liljenbäck, H. Lönnberg, A. Roivainen, 2014, Bioorganic & medicinal chemistry.

Solid-supported NOTA and DOTA chelators useful for the synthesis of 3'-radiometalated oligonucleotides.

H. Liljenbäck, H. Lönnberg, A. Roivainen, 2012, Bioconjugate chemistry.

Resorption-cycle-dependent polarization of mRNAs for different subunits of V-ATPase in bone-resorbing osteoclasts.

G. E. Dean, M. Howell, H. Väänänen, 1996, Molecular biology of the cell.

Impaired bone resorption in cathepsin K-deficient mice is partially compensated for by enhanced osteoclastogenesis and increased expression of other proteases via an increased RANKL/OPG ratio.

E. Vuorio, J. Risteli, R. Kiviranta, 2005, Bone.

Synthesis and In Vivo PET Imaging of Hyaluronan Conjugates of Oligonucleotides.

S. Jalkanen, V. Kytö, A. Saraste, 2016, Bioconjugate chemistry.

Decreased bone resorption, osteoclast differentiation, and expression of vacuolar H+-ATPase in antisense DNA-treated mouse metacarpal and calvaria cultures ex vivo.

H. Väänänen, T. Laitala-Leinonen, 1999, Antisense & nucleic acid drug development.

FATEMEH BOOTORABI ( AHMAD ) Production and Characterization of Carbonic Anhydrase VII

V. Marjomäki, J. Visakorpi, T. Laitala-Leinonen, 2011 .

RNA Interference Tolerates 2′‐Fluoro Modifications at the Argonaute2 Cleavage Site

Pirkko Muhonen, A. Azhayev, H. Väänänen, 2007, Chemistry & biodiversity.

Do microRNAs regulate bone marrow stem cell niche physiology?

T. Hentunen, T. Laitala-Leinonen, S. Laine, 2012, Gene.

Osteoclast lineage and function.

Tiina Laitala-Leinonen, H. Väänänen, H Kalervo Väänänen, 2008, Archives of biochemistry and biophysics.

MicroRNAs Regulate Osteogenesis and Chondrogenesis of Mouse Bone Marrow Stromal Cells

A. Säämänen, K. Väänänen, H. Taipaleenmäki, 2008, Gene regulation and systems biology.

Membrane-bound carbonic anhydrases in osteoclasts.

C. Supuran, S. Pastoreková, S. Parkkila, 2007, Bone.

Snorc is a novel cartilage specific small membrane proteoglycan expressed in differentiating and articular chondrocytes.

I. Kiviranta, A. Säämänen, M. Kassem, 2011, Osteoarthritis and cartilage.

Calcific spurs at the insertion of the Achilles tendon: a clinical and histological study.

S. Orava, J. Sarimo, T. Laitala-Leinonen, 2012, Muscles, ligaments and tendons journal.

Macroscopic Anomalies and Pathological Findings in and Around the Achilles Tendon

S. Orava, J. Sarimo, T. Laitala-Leinonen, 2014, Orthopaedic journal of sports medicine.

Degradation of hydroxyapatite in vivo and in vitro requires osteoclastic sodium-bicarbonate co-transporter NBCn1.

T. Kwon, H. Väänänen, T. Laitala-Leinonen, 2010, Matrix biology : journal of the International Society for Matrix Biology.

In Vivo Bone-Targeting of Bis(phosphonate)-Conjugated Double Helical RNA Monitored by Positron Emission Tomography.

H. Liljenbäck, H. Lönnberg, A. Roivainen, 2016, Molecular pharmaceutics.

Update on the development of microRNA and siRNA molecules as regulators of cell physiology.

Tiina Laitala-Leinonen, T. Laitala-Leinonen, 2010, Recent patents on DNA & gene sequences.

Adolescent athletes with learning disability display atypical maturational trajectories on concussion baseline testing: Implications based on a Finnish sample

S. Koskinen, L. Hokkanen, Jon L. Pertab, 2019, Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence.

Impact of stromal cell composition on BMP-induced chondrogenic differentiation of mouse bone marrow derived mesenchymal cells.

A. Säämänen, H. Taipaleenmäki, T. Hentunen, 2008, Experimental cell research.

MicroRNAs miR‐96, miR‐124, and miR‐199a regulate gene expression in human bone marrow‐derived mesenchymal stem cells

J. Alm, T. Laitala-Leinonen, H. Aro, 2012, Journal of cellular biochemistry.

Noninvasive and Quantitative Monitoring of the Distributions and Kinetics of MicroRNA-Targeting Molecules in Vivo by Positron Emission Tomography

H. Liljenbäck, H. Lönnberg, A. Roivainen, 2019, Molecular pharmaceutics.

MicroRNAs miR‐96, miR‐124, and miR‐199a regulate gene expression in human bone marrow‐derived mesenchymal stem cells

J. Alm, T. Laitala-Leinonen, H. Aro, 2012, Journal of cellular biochemistry.

Macroscopic Anomalies and Pathological Findings in and Around the Achilles Tendon

S. Orava, J. Sarimo, T. Laitala-Leinonen, 2014, Orthopaedic journal of sports medicine.