R. Zuiker

发表

Pharmacokinetics of intravenous and inhaled salbutamol and tobramycin: An exploratory study to investigate the potential of exhaled breath condensate as a matrix for pharmacokinetic analysis

A. Cohen, M. Dröge, M. Kruizinga, 2020, British journal of clinical pharmacology.

Efficacy and safety of RPL554, a dual PDE3 and PDE4 inhibitor, in healthy volunteers and in patients with asthma or chronic obstructive pulmonary disease: findings from four clinical trials.

M. Cazzola, Dave Singh, M. D. de Kam, 2013, The Lancet. Respiratory medicine.

Driving Performance after Bedtime Administration of Daridorexant, Assessed in a Sensitive Simulator

J. Dingemanse, Michael Meinel, Clemens Muehlan, 2022, Clinical pharmacology and therapeutics.

Kinetics of TH2 biomarkers in sputum of asthmatics following inhaled allergen

R. Mogg, Z. Diamant, I. Kamerling, 2015, European clinical respiratory journal.

Sputum induction with hypertonic saline reduces fractional exhaled nitric oxide in chronic smokers and non-smokers.

M. D. de Kam, Z. Diamant, K. Petty, 2010, Respiratory medicine.

Translational evaluation of novel selective orexin-1 receptor antagonist JNJ-61393215 in an experimental model for panic in rodents and humans

T. P. Lebold, P. Bonaventure, W. Drevets, 2020, Translational Psychiatry.

Pharmacokinetics and pharmacodynamics of a new highly concentrated intranasal midazolam formulation for conscious sedation

J. V. van Gerven, G. Groeneveld, L. Schrier, 2017, British journal of clinical pharmacology.

Central nervous system effects of TAK-653, an investigational alpha-amino-3-hydroxy-5-methyl-4-isoxazole receptor (AMPAR) positive allosteric modulator in healthy volunteers

D. Buhl, P. O’Donnell, J. V. van Gerven, 2022, Translational Psychiatry.

Pharmacological profile of ALKS 7119, an investigational compound evaluated for the treatment of neuropsychiatric disorders, in healthy volunteers

J. V. van Gerven, M. D. de Kam, L. V. von Moltke, 2022, British journal of clinical pharmacology.

The perception and pharmacokinetics of a 20-mg dose of escitalopram orodispersible tablets in a relative bioavailability study in healthy men.

J. V. van Gerven, R. Zuiker, D. Nilausen, 2011, Clinical therapeutics.

Population pharmacokinetics of clonazepam in saliva and plasma: Steps towards noninvasive pharmacokinetic studies in vulnerable populations

A. Cohen, M. Kruizinga, M. V. van Esdonk, 2021, British journal of clinical pharmacology.

Glutathione‐PEGylated liposomal methylprednisolone in comparison to free methylprednisolone: slow release characteristics and prolonged lymphocyte depression in a first‐in‐human study

P. Gaillard, W. Gladdines, G. Groeneveld, 2018, British journal of clinical pharmacology.

The selective orexin-2 antagonist seltorexant (JNJ-42847922/MIN-202) shows antidepressant and sleep-promoting effects in patients with major depressive disorder

W. Drevets, R. Luthringer, J. V. van Gerven, 2019, Translational Psychiatry.

Central nervous system effects of the histamine‐3 receptor antagonist CEP‐26401, in comparison with modafinil and donepezil, after a single dose in a cross‐over study in healthy volunteers

J. V. van Gerven, A. Gershon, E. Hellriegel, 2019, British journal of clinical pharmacology.

Effect of intranasal esketamine on cognitive functioning in healthy participants: a randomized, double-blind, placebo-controlled study

W. Drevets, J. V. van Gerven, Jaskaran Singh, 2016, Psychopharmacology.

The effects of intranasal esketamine (84 mg) and oral mirtazapine (30 mg) on on-road driving performance: a double-blind, placebo-controlled study

J. Verster, J. V. van Gerven, J. Garssen, 2017, Psychopharmacology.

Characterisation of the pharmacodynamic effects of the P2X7 receptor antagonist JNJ-54175446 using an oral dexamphetamine challenge model in healthy males in a randomised, double-blind, placebo-controlled, multiple ascending dose trial

W. Drevets, J. V. van Gerven, M. D. de Kam, 2020, Journal of psychopharmacology.

Transcranial magnetic stimulation as a translational biomarker for AMPA receptor modulation

D. Buhl, P. O’Donnell, A. Rotenberg, 2021, Translational Psychiatry.

Clinical pharmacology of the dual orexin receptor antagonist ACT-541468 in elderly subjects: Exploration of pharmacokinetics, pharmacodynamics and tolerability following single-dose morning and repeated-dose evening administration

J. V. van Gerven, J. Dingemanse, Clemens Muehlan, 2020, Journal of psychopharmacology.

Multiple-dose clinical pharmacology of ACT-541468, a novel dual orexin receptor antagonist, following repeated-dose morning and evening administration

J. V. van Gerven, J. Dingemanse, Clemens Muehlan, 2019, European Neuropsychopharmacology.

Sputum RNA signature in allergic asthmatics following allergen bronchoprovocation test

A. Cohen, J. Burggraaf, Z. Diamant, 2016, European clinical respiratory journal.

Evaluation of simulated driving in comparison to laboratory-based tests to assess the pharmacodynamics of alprazolam and alcohol

J. V. van Gerven, M. D. de Kam, A. Cohen, 2019, Journal of psychopharmacology.

NS11821, a partial subtype-selective GABAA agonist, elicits selective effects on the central nervous system in randomized controlled trial with healthy subjects

P. Muglia, J. V. van Gerven, M. D. de Kam, 2016, Journal of psychopharmacology.

The selective orexin-2 receptor antagonist seltorexant improves sleep: An exploratory double-blind, placebo controlled, crossover study in antidepressant-treated major depressive disorder patients with persistent insomnia

W. Drevets, R. Luthringer, J. V. van Gerven, 2019, Journal of psychopharmacology.

Pharmacological Interactions between the Dual Orexin Receptor Antagonist Daridorexant and Ethanol in a Double-Blind, Randomized, Placebo-Controlled, Double-Dummy, Four-Way Crossover Phase I Study in Healthy Subjects

B. Berger, J. Dingemanse, Clemens Muehlan, 2020, CNS Drugs.

A first-in-human study in healthy subjects of the safety and pharmacokinetics of CNM-Au8, a suspension of catalytically active gold nanocrystals with remyelinating and neuroprotective properties

K. McBride, M. Moerland, G. Groeneveld, 2023, medRxiv.

Effects of a single, oral 60 mg caffeine dose on attention in healthy adult subjects

J. V. van Gerven, M. Beaumont, J. Schmitt, 2017, Journal of psychopharmacology.

Reproducibility of biomarkers in induced sputum and in serum from chronic smokers.

M. D. de Kam, A. Cohen, J. Burggraaf, 2015, Pulmonary pharmacology & therapeutics.

Pharmacokinetics and Pharmacodynamics of the Dual Orexin Receptor Antagonist Daridorexant in Japanese and Caucasian Subjects.

J. Dingemanse, Clemens Muehlan, P. Peeters, 2020, Journal of clinical psychopharmacology.

Pharmacological interactions between brivaracetam and ethanol in healthy males

J. V. van Gerven, M. D. de Kam, J. Stevens, 2017, Journal of psychopharmacology.