Ondřej Šimák

发表

Spectroscopic, morphological, and mechanistic investigation of the solvent-promoted aggregation of porphyrins modified in meso-positions by glucosylated steroids.

G. Mancini, D. Monti, M. Venanzi, 2011, Chemistry.

Discovery of isonucleotidic CDNs as potent STING agonists with immunomodulatory potential.

E. Bouřa, M. Dračínský, M. Buděšínský, 2022, Structure.

Lipophosphonoxins II: Design, Synthesis, and Properties of Novel Broad Spectrum Antibacterial Agents.

O. Benada, R. Pohl, H. Šanderová, 2017, Journal of medicinal chemistry.

Methyl 4-toluenesulfonyloxymethylphosphonate, a new and versatile reagent for the convenient synthesis of phosphonate-containing compounds

M. Buděšínský, I. Rosenberg, D. Rejman, 2009 .

4-Toluenesulfonyloxymethyl-(H)-phosphinate: A Reagent for the Introduction of O- and S-Methyl-(H)-phosphinate Moieties.

M. Buděšínský, I. Rosenberg, O. Páv, 2016, Organic letters.

Conformationally constrained nucleoside phosphonic acids--potent inhibitors of human mitochondrial and cytosolic 5'(3')-nucleotidases.

J. Brynda, V. Veverka, P. Řezáčová, 2014, Organic & biomolecular chemistry.

Inhibition of human thymidine phosphorylase by conformationally constrained pyrimidine nucleoside phosphonic acids and their "open-structure" isosteres.

M. Buděšínský, I. Rosenberg, D. Rejman, 2014, European journal of medicinal chemistry.

A stereocontrolled synthesis of 3-acetamido-1,3,5-trideoxy- and 1,3,5,6-tetradeoxy-1,5-imino-D-glucitol.

J. Stanek, J. Moravcova, Ondřej Šimák, 2009, Carbohydrate research.

5'-Phosphonate modified oligoadenylates as potent activators of human RNase L.

M. Buděšínský, G. Birkuš, I. Rosenberg, 2022, Bioorganic & medicinal chemistry.

5′-O-Methylphosphonate nucleic acids—new modified DNAs that increase the Escherichia coli RNase H cleavage rate of hybrid duplexes

J. Homola, I. Barvík, Hana Šípová, 2014, Nucleic acids research.

Asymmetrically substituted calix[4]pyrrole with chiral substituents.

P. Štěpánek, P. Drasar, Z. Wimmer, 2011, Organic & biomolecular chemistry.

Tuning the hybridization properties of modified oligonucleotides: from flexible to conformationally constrained phosphonate internucleotide linkages.

I. Barvík, M. Buděšínský, I. Rosenberg, 2017, Organic & biomolecular chemistry.

Insights into the Mechanism of Action of Bactericidal Lipophosphonoxins

R. Pohl, H. Šanderová, I. Barvík, 2015, PloS one.

Straightforward Synthesis of Purine 4'-Alkoxy-2'-deoxynucleosides: First Report of Mixed Purine-Pyrimidine 4'-Alkoxyoligodeoxynucleotides as New RNA Mimics.

M. Buděšínský, I. Rosenberg, Eva Zborníková, 2015, Organic letters.

Oligomerization of adenosin‐5′‐O‐ylmethylphosphonate, an isopolar AMP analogue: Evaluation of the route to short oligoadenylates

V. Kopecký, J. Cvačka, M. Buděšínský, 2010, Biopolymers.

Structure-Based Optimization of Bisphosphonate Nucleoside Inhibitors of Human 5′(3′)-deoxyribonucleotidases

J. Brynda, P. Řezáčová, M. Buděšínský, 2018, European Journal of Organic Chemistry.

Structures of human cytosolic and mitochondrial nucleotidases: implications for structure-based design of selective inhibitors.

J. Brynda, P. Řezáčová, I. Rosenberg, 2014, Acta crystallographica. Section D, Biological crystallography.

Structure-based design of a bisphosphonate 5′(3′)-deoxyribonucleotidase inhibitor

J. Brynda, P. Řezáčová, M. Buděšínský, 2015 .