N. Pugh

发表

Differential integrin activity mediated by platelet collagen receptor engagement under flow conditions

D. Bihan, R. Farndale, K. A. Taylor, 2017, Thrombosis and Haemostasis.

Synergism between platelet collagen receptors defined using receptor-specific collagen-mimetic peptide substrata in flowing blood.

P. D. de Groot, P. Smethurst, R. Farndale, 2010, Blood.

Zinc is a transmembrane agonist that induces platelet activation in a tyrosine phosphorylation-dependent manner.

D. Bihan, R. Farndale, Jean-Daniel M. Malcor, 2016, Metallomics : integrated biometal science.

Dynamic analysis of platelet deposition to resolve platelet adhesion receptor activity in whole blood at arterial shear rate

D. Perry, D. Bihan, R. Farndale, 2014, Platelets.

Thrombospondin-1 promotes matrix homeostasis by interacting with collagen and lysyl oxidase precursors and collagen cross-linking sites

Josephine C. Adams, D. Hulmes, A. Bonna, 2018, Science Signaling.

Zinc regulates reactive oxygen species generation in platelets

D. Vara, J. Gibbins, M. Lopes-Pires, 2020, Platelets.

The contribution of zinc to platelet behaviour during haemostasis and thrombosis.

K. A. Taylor, N. Pugh, Kirk A. Taylor, 2016, Metallomics : integrated biometal science.

The impact of factor Xa inhibition on axial dependent arterial thrombus formation triggered by a tissue factor rich surface

R. Farndale, K. Sakariassen, G. Jarvis, 2011, Journal of Thrombosis and Thrombolysis.

Cell-collagen interactions: the use of peptide Toolkits to investigate collagen-receptor interactions.

P. D. de Groot, D. Bihan, R. Farndale, 2008, Biochemical Society transactions.

Agonist-Evoked Increases in Intra-Platelet Zinc Couple to Functional Responses

K. A. Taylor, N. Pugh, N. S. Ahmed, 2018, Thrombosis and haemostasis.

OSCAR is a collagen receptor that costimulates osteoclastogenesis in DAP12-deficient humans and mice.

J. Trowsdale, H. Takayanagi, M. Colonna, 2011, The Journal of clinical investigation.

Putative GTPase GIMAP1 is critical for the development of mature B and T lymphocytes.

G. Morgan, C. Carter, G. Butcher, 2010, Blood.

Anti‐thrombotic efficacy of S007‐867: Pre‐clinical evaluation in experimental models of thrombosis in vivo and in vitro

M. Dikshit, M. Barthwal, D. Bihan, 2018, Biochemical pharmacology.

Mapping of Potent and Specific Binding Motifs, GLOGEN and GVOGEA, for Integrin α1β1 Using Collagen Toolkits II and III*

D. Bihan, R. Farndale, D. Gullberg, 2012, The Journal of Biological Chemistry.

Constitutive Dimerization of Glycoprotein VI (GPVI) in Resting Platelets Is Essential for Binding to Collagen and Activation in Flowing Blood*

S. Watson, T. Nakagaki, D. Bihan, 2012, The Journal of Biological Chemistry.

The properties conferred upon triple-helical collagen-mimetic peptides by the presence of cysteine residues

D. Slatter, D. Bihan, R. Farndale, 2012, Peptides.

Extracellular chloride is required for efficient platelet aggregation

K. A. Taylor, M. Harper, N. Pugh, 2017, Platelets.

A role for adhesion and degranulation‐promoting adapter protein in collagen‐induced platelet activation mediated via integrin α2β1

S. Watson, C. Rudd, C. Hughes, 2012, Journal of thrombosis and haemostasis : JTH.

Platelet Isolation and Activation Assays.

M. Clarke, N. Pugh, L. Burzynski, 2019, Bio-protocol.

MMP‐13 binds to platelet receptors αIIbβ3 and GPVI and impairs aggregation and thrombus formation

R. Farndale, V. Knäuper, S. Hamaia, 2018, Research and practice in thrombosis and haemostasis.

Zinc: an endogenous and exogenous regulator of platelet function during hemostasis and thrombosis

M. Lopes-Pires, N. Pugh, N. S. Ahmed, 2020, Platelets.

Pericellular Ca2+ recycling potentiates thrombin-evoked Ca2+ signals in human platelets

R. Farndale, S. Sage, A. Harper, 2013, Physiological reports.

Monitoring the intracellular store Ca2+ concentration in agonist‐stimulated, intact human platelets by using Fluo‐5N

S. Sage, M. J. Mason, A. Harper, 2011, Journal of thrombosis and haemostasis : JTH.

Crosslinking and composition influence the surface properties, mechanical stiffness and cell reactivity of collagen-based films

Serena M. Best, Richard W. Farndale, Ruth E. Cameron, 2012, Acta Biomaterialia.

Identification of platelet function defects by multi-parameter assessment of thrombus formation

Rachel Cavill, Richard W. Farndale, A. Schulz, 2014, Nature Communications.

First Analysis of a Bacterial Collagen-Binding Protein with Collagen Toolkits: Promiscuous Binding of YadA to Collagens May Explain How YadA Interferes with Host Processes

A. Goldman, H. Elovaara, M. Skurnik, 2010, Infection and Immunity.

Expression of the Ian family of putative GTPases during T cell development and description of an Ian with three sets of GTP/GDP-binding motifs.

G. Anderson, J. Miller, G. Morgan, 2005, International immunology.

Modified platelet deposition on matrix metalloproteinase 13 digested collagen I

R. Farndale, V. Knäuper, N. Pugh, 2015, Journal of thrombosis and haemostasis : JTH.

Agonist-Evoked Increases in Intra-Platelet Zinc Couple to Functional Responses

K. A. Taylor, N. Pugh, N. S. Ahmed, 2018, Thrombosis and Haemostasis.

Delineating Zinc Influx Mechanisms during Platelet Activation

J. Gibbins, S. Kuravi, A. Unsworth, 2023, International Journal of Molecular Sciences.

Single domain antibodies against the collagen signalling receptor glycoprotein VI are inhibitors of collagen induced thrombus formation

W. Ouwehand, J. Stephens, S. Garner, 2009, Platelets.

Stapled peptides as a new technology to investigate protein–protein interactions in human platelets

D. Spring, Y. S. Tan, C. Verma, 2018, Chemical science.

A role for adhesion and degranulation‐promoting adapter protein in collagen‐induced platelet activation mediated via integrin α2β1

C. Hughes, D. Bihan, R. Farndale, 2012, Journal of thrombosis and haemostasis : JTH.