D. Hendriks

发表

A role for procarboxypepidase U (TAFI) in thrombosis.

J. Willemse, D. Hendriks, 2007, Frontiers in bioscience : a journal and virtual library.

Carboxypeptidase U, a plasma carboxypeptidase with high affinity for plasminogen.

D. Hendriks, W. Wang, S. Scharpé, 1994, The Journal of biological chemistry.

Assay of procarboxypeptidase U, a novel determinant of the fibrinolytic cascade, in human plasma.

H. Neels, F. Goossens, D. Hendriks, 1999, Clinical chemistry.

Characterization of dipeptidyl peptidase IV (CD26) from human lymphocytes.

G. Vanhoof, I. De Meester, H. Demuth, 1992, Clinica chimica acta; international journal of clinical chemistry.

Plasma carboxypeptidase U (CPU, CPB2, TAFIa) generation during in vitro clot lysis and its interplay between coagulation and fibrinolysis

J. Aernouts, A. Lambeir, P. Van der Veken, 2017, Thrombosis and Haemostasis.

Carboxypeptidase U (TAFIa) activity is induced in vivo in ischemic stroke patients receiving thrombolytic therapy

P. D. De Deyn, R. Brouns, P. De Deyn, 2007, Journal of thrombosis and haemostasis : JTH.

Carboxypeptidase U (TAFIa) Is Rapidly Activated and Deactivated Following Thrombolysis and Thrombectomy in Stroke Patients

B. Tyl, C. Molina, J. Mertens, 2021, Translational Stroke Research.

Selective inhibition of carboxypeptidase U may reduce microvascular thrombosis in rat experimental stroke

J. Michel, J. Desilles, M. Mazighi, 2020, Journal of thrombosis and haemostasis : JTH.

Carboxypeptidase U (TAFIa): a new drug target for fibrinolytic therapy?

M. Nesheim, J. Willemse, D. Hendriks, 2009, Journal of thrombosis and haemostasis : JTH.

Procarboxypeptidase U (TAFI) contributes to the risk of thrombosis in patients with hereditary thrombophilia.

D. Radojkovic, P. Miljić, I. Elezović, 2009, Thrombosis research.

Different effects of low-dose transdermal and oral oestrogen therapy on procarboxypeptidase U, an inhibitor of fibrinolysis, in healthy postmenopausal women: A randomised, placebo-controlled study

C. Stehouwer, W. M. van Baal, P. Kenemans, 2005, Thrombosis and Haemostasis.

Local proCPU (TAFI) Activation during Thrombolytic Treatment in a Dog Model of Coronary Artery Thrombosis can be Inhibited with a Direct, Small Molecule Thrombin Inhibitor (Melagatran)

V. Nerme, J. Björkman, C. Mattsson, 2002, Thrombosis and Haemostasis.

Hairy cell leukemia cell lines expressing annexin A1 and displaying B-cell receptor signals characteristic of primary tumor cells lack the signature BRAF mutation to reveal unrepresentative origins

H. Kluin-Nelemans, N. Bos, F. Forconi, 2013, Leukemia.

Purification and characterization of a new arginine carboxypeptidase in human serum.

S. Scharpe, D. Hendriks, W. Wang, 1990, Biochimica et biophysica acta.

Plasma Procarboxypeptidase U in Men with Symptomatic Coronary Artery Disease

A. Hamsten, A. Silveira, F. Goossens, 2000, Thrombosis and Haemostasis.

The role of the S1 binding site of carboxypeptidase M in substrate specificity and turn-over.

A. Lambeir, K. Gilany, G. Surpateanu, 2007, Biochimica et biophysica acta.

Assay of dipeptidyl peptidase IV in serum by fluorometry of 4-methoxy-2-naphthylamine.

G. Vanhoof, I. De Meester, S. Scharpe, 1988, Clinical chemistry.

Development of a fast kinetic method for the determination of carboxypeptidase U (TAFIa) using C-terminal arginine containing peptides as substrate.

R. Verkerk, J. Willemse, D. Hendriks, 2005, Analytical biochemistry.

Oral oestradiol/trimegestone replacement reduces procarboxypeptidase U (TAFI): a randomized, placebo‐ controlled, 12‐week study in early postmenopausal women

C. Stehouwer, W. M. van Baal, P. Kenemans, 2002, Journal of internal medicine.

Components of biological variation in serum soluble transferrin receptor: relationships to serum iron, transferrin and ferritin concentrations, and immune and haematological variables.

E. Bosmans, H. Neels, M. Maes, 1997, Scandinavian journal of clinical and laboratory investigation.

Carboxypeptidase U (CPU, TAFIa, CPB2) in Thromboembolic Disease: What Do We Know Three Decades after Its Discovery?

J. Mertens, D. Hendriks, D. Leenaerts, 2021, International journal of molecular sciences.

Inhibition of the procarboxypeptidase U (proCPU, TAFI, proCPB2) system due to hemolysis

A. Lambeir, J. Mertens, D. Hendriks, 2019, Journal of thrombosis and haemostasis : JTH.

Plasma levels of carboxypeptidase U (CPU, CPB2 or TAFIa) are elevated in patients with acute myocardial infarction

A. Lambeir, J. Bosmans, P. Veken, 2015, Journal of thrombosis and haemostasis : JTH.

The decrease in procarboxypeptidase U (TAFI) concentration in acute ischemic stroke correlates with stroke severity, evolution and outcome

P. D. De Deyn, R. Brouns, R. Sheorajpanday, 2010, Journal of thrombosis and haemostasis : JTH.

Measurement of carboxypeptidase U (active thrombin-activatable fibrinolysis inhibitor) in plasma: Challenges overcome by a novel selective assay.

K. Augustyns, S. Van Goethem, D. Hendriks, 2010, Analytical biochemistry.

Measurement of procarboxypeptidase U (TAFI) in human plasma: a laboratory challenge.

J. Willemse, D. Hendriks, 2006, Clinical chemistry.

Acute ischemic stroke severity , progression and outcome relates to changes in dipeptidyl peptidase IV and fibroblast activation protein activity Reference

Sebastiaan, Brouns, P. Deyn, 2016 .

Carboxypeptidase U (TAFIa): a metallocarboxypeptidase with a distinct role in haemostasis and a possible risk factor for thrombotic disease

D. Hendriks, J. Leurs, 2005, Thrombosis and Haemostasis.

Carboxypeptidase U (TAFIa) prevents lysis from proceeding into the propagation phase through a threshold‐dependent mechanism

V. Nerme, D. Hendriks, Y. Sim, 2004, Journal of thrombosis and haemostasis : JTH.

A labile enzyme in fresh human serum interferes with the assay of carboxypeptidase N.

S. Scharpe, D. Hendriks, M. Lommaert, 1989, Clinical chemistry.

Characterisation of a Carboxypeptidase in Human Serum Distinct from Carboxypeptidase N

S. Scharpe, D. Hendriks, M. Lommaert, 1989, Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie.

Raloxifene reduces procarboxypeptidase U, an antifibrinolytic marker. A 2-year randomized, placebo-controlled study in healthy early postmenopausal women

P. Kenemans, T. Vogelvang, J. C. Netelenbos, 2004, Menopause.

Kininase activity in human platelets: cleavage of the Arg1-Pro2 bond of bradykinin by aminopeptidase P.

G. Vanhoof, I. De Meester, S. Scharpe, 1992, Biochemical pharmacology.

Aminopeptidase P and dipeptidyl peptidase IV activity in human leukocytes and in stimulated lymphocytes.

G. Vanhoof, I. De Meester, S. Scharpe, 1991, Clinica chimica acta; international journal of clinical chemistry.

Exopeptidases in human platelets: an indication for proteolytic modulation of biologically active peptides.

G. Vanhoof, I. De Meester, S. Scharpe, 1991, Clinica chimica acta; international journal of clinical chemistry.

Dipeptidyl peptidase IV in human lymphocytes: molecular properties.

G. Vanhoof, I. De Meester, S. Scharpe, 1990, Biochemical Society transactions.

Thrombin-activatable fibrinolysis inhibitor aka procarboxypeptidase U

M. Nesheim, D. Hendriks, J. Leurs, 2006 .

Dipeptidyl peptidase IV activity in stimulated T lymphocytes

G. Vanhoof, S. Scharpe, T. Umiel, 1988 .

arboxypeptidase U at the Interface Between Coagulation and Fibrinolysis

F. Goossens, R. Verkerk, J. Michiels, 2001 .

Characterization of the erythropoiesis in myelodysplasia by means of ferrokinetic studies, in vitro erythroid colony formation and soluble transferrin receptor

E. Vellenga, E. Berg, D. Hendriks, 1998, Leukemia.

Effect of Statin Therapy on the Carboxypeptidase U (CPU, TAFIa, CPB2) System in Patients With Hyperlipidemia: A Proof-of-Concept Observational Study.

I. De Meester, J. Maes, J. Mertens, 2021, Clinical therapeutics.

LETTERS TO THE EDITOR: Fast kinetic assay for the determination of procarboxypeptidase U (TAFI) in human plasma

J. Willemse, D. Hendriks, J. Leurs, 2005, Journal of thrombosis and haemostasis : JTH.

Procarboxypeptidase U (TAFI) and the Thr325Ile proCPU polymorphism in patients with hereditary mucocutaneous hemorrhages.

O. Panes, V. Matus, T. Quiroga, 2009, Clinica chimica acta; international journal of clinical chemistry.

Identification of the carboxypeptidase responsible for the post-synthetic modification of creatine kinase in human serum.

R. Wevers, S. Scharpe, J. Soons, 1988, Clinica chimica acta; international journal of clinical chemistry.

Carboxypeptidase U (CPU, carboxypeptidase B2, activated thrombin‐activatable fibrinolysis inhibitor) inhibition stimulates the fibrinolytic rate in different in vitro models

J. Michel, A. Lambeir, J. Mertens, 2018, Journal of thrombosis and haemostasis : JTH.

Prolyl Carboxypeptidase Activity Decline Correlates with Severity and Short-Term Outcome in Acute Ischemic Stroke

P. Deyn, S. Engelborghs, R. Brouns, 2014, Neurochemical Research.

Immunological Assay for the Determination of Procarboxypeptidase U Antigen Levels in Human Plasma

R. Verkerk, M. Strömqvist, D. Hendriks, 2001, Thrombosis and Haemostasis.

Proteolytic activation of purified human procarboxypeptidase U.

F. Goossens, D. Hendriks, S. Scharpé, 2000, Clinica chimica acta; international journal of clinical chemistry.

Properties of recombinant human plasma procarboxypeptidase U produced in mammalian and insect cells.

Thord Johansson, M. Enoksson, S. Scharpe, 2004, Clinica chimica acta; international journal of clinical chemistry.

Dipeptide-derived diphenyl phosphonate esters: mechanism-based inhibitors of dipeptidyl peptidase IV.

A. Lambeir, I. De Meester, A. Haemers, 1996, Biochimica et Biophysica Acta.

Proline motifs in peptides and their biological processing

Greet Vanhoof, G. Vanhoof, I. De Meester, 1995, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Acute Ischemic Stroke Severity, Progression, and Outcome Relate to Changes in Dipeptidyl Peptidase IV and Fibroblast Activation Protein Activity

S. Engelborghs, I. De Meester, R. Brouns, 2016, Translational Stroke Research.

Carboxypeptidase M: Multiple alliances and unknown partners.

A. Lambeir, S. Scharpe, D. Hendriks, 2009, Clinica chimica acta; international journal of clinical chemistry.

The purification, characterization and analysis of primary and secondary-structure of prolyl oligopeptidase from human lymphocytes. Evidence that the enzyme belongs to the alpha/beta hydrolase fold family.

G. Vriend, G. Vanhoof, I. De Meester, 1995, European journal of biochemistry.

Mapping of Carboxypeptidase M in Normal Human Kidney and Renal Cell Carcinoma

A. Lambeir, E. Fransen, M. Kockx, 2013, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Carboxypeptidase M in apoptosis, adipogenesis and cancer.

P. Proost, A. Lambeir, D. Hendriks, 2013, Clinica chimica acta; international journal of clinical chemistry.

Proteases and their inhibitors: today and tomorrow.

G. Vriend, G. Vanhoof, I. De Meester, 1991, Biochimie.

An update on the role of carboxypeptidase U (TAFIa) in fibrinolysis.

J. Willemse, D. Hendriks, E. Heylen, 2011, Frontiers in bioscience.

Carboxypeptidase N: colorimetric assay using a new substrate.

S. Scharpe, D. Hendriks, Y. Kasahara, 1987, Analytical biochemistry.

Assay of carboxypeptidase N activity in serum by liquid-chromatographic determination of hippuric acid.

S. Scharpe, D. Hendriks, M. V. van Sande, 1985, Clinical chemistry.

Colorimetric assay for carboxypeptidase N in serum.

S. Scharpe, D. Hendriks, M. V. van Sande, 1986, Clinica chimica acta; international journal of clinical chemistry.

Development of a Genotype 325–Specific proCPU/TAFI ELISA

Els Brouwers, Ann Gils, A. Gils, 2003, Arteriosclerosis, thrombosis, and vascular biology.

Activation of the Carboxypeptidase U (CPU, TAFIa, CPB2) System in Patients with SARS-CoV-2 Infection Could Contribute to COVID-19 Hypofibrinolytic State and Disease Severity Prognosis

I. De Meester, S. Kumar-Singh, E. Vlieghe, 2022, Journal of clinical medicine.

35th Annual meeting of the European Association for the Study of Diabetes. Brussels, Belgium, 28 September-2 October, 1999. Abstracts.

Thomas J. Smith, B. M. Rasmussen, V. C. Phan, 1999, Diabetologia.

Cloning and sequence analysis of the gene encoding human lymphocyte prolyl endopeptidase.

G Vriend, G. Vriend, C. Broeckhoven, 1994, Gene.

Influence of academic examination stress on hematological measurements in subjectively healthy volunteers

Aleksandar Janca, Michael Maes, H. Neels, 1998, Psychiatry Research.

Effects of psychological stress on serum immunoglobulin, complement and acute phase protein concentrations in normal volunteers

H. Neels, M. Maes, A. Gastel, 1997, Psychoneuroendocrinology.

Pyrrolidides: synthesis and structure-activity relationship as inhibitors of dipeptidyl peptidase IV

A. Haemers, Koen Augustyns, G. Vanhoof, 1997 .

Limited mutagenesis increases the stability of human carboxypeptidase U (TAFIa) and demonstrates the importance of CPU stability over proCPU concentration in down‐regulating fibrinolysis

P. Cronet, H. Stenhamre, Anna Harrysson, 2006, The FEBS journal.

Human lymphocyte X-prolyl aminopeptidase (aminopeptidase P)-like protein. A new member of the proline peptidase family?

G. Vanhoof, L. Juliano, M. Juliano, 1997, Advances in experimental medicine and biology.

Isolation and sequence analysis of a human cDNA clone (XPNPEPL) homologous to X-prolyl aminopeptidase (aminopeptidase P).

G. Vanhoof, L. Juliano, M. Juliano, 1997, Cytogenetics and Cell Genetics.

The gene for human carboxypeptidase U (CPU)--a proposed novel regulator of plasminogen activation--maps to 13q14.11.

G. Vanhoof, S. Scharpe, F. Goossens, 1996, Genomics.

A new pedigree with thrombomodulin‐associated coagulopathy in which delayed fibrinolysis is partially attenuated by co‐inherited TAFI deficiency

K. Downes, J. Stephens, E. Turro, 2020, Journal of thrombosis and haemostasis : JTH.

Procarboxypeptidase U (proCPU, TAFI, proCPB2) in cerebrospinal fluid during ischemic stroke is associated with stroke progression, outcome and blood–brain barrier dysfunction

A. Lambeir, R. Brouns, M. Ieven, 2018, Journal of thrombosis and haemostasis : JTH.

Carboxypeptidase U at the interface between coagulation and fibrinolysis.

F. Goossens, R. Verkerk, J. Michiels, 2001, Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis.

Different mechanisms contribute to the biphasic pattern of carboxypeptidase U (TAFIa) generation during in vitro clot lysis in human plasma

P. Björquist, V. Nerme, D. Hendriks, 2003, Thrombosis and Haemostasis.

Ethanol dependence of α1‐antitrypsin C‐terminal Lys truncation mediated by basic carboxypeptidases

H. Ehrlich, H. Schwarz, H. P. Matthiessen, 2008, Transfusion.

Carboxypeptidase U (TAFIa) decreases the efficacy of thrombolytic therapy in ischemic stroke patients

P. Deyn, R. Brouns, R. Sheorajpanday, 2009, Clinical Neurology and Neurosurgery.

The intrinsic enzymatic activity of procarboxypeptidase U (TAFI) does not significantly influence the fibrinolysis rate: a rebuttal

J. Willemse, D. Hendriks, E. Heylen, 2007, Journal of thrombosis and haemostasis : JTH.

The intrinsic enzymatic activity of plasma procarboxypeptidase U (TAFI) can interfere with plasma carboxypeptidase N assays.

J. Willemse, D. Hendriks, M. Polla, 2006, Analytical biochemistry.

Activation of Plasma Procarboxypeptidase U in Different Mammalian Species Points to a Conserved Pathway of Inhibition of Fibrinolysis

F. Goossens, D. Hendriks, S. Scharpé, 1999, Thrombosis and Haemostasis.

Influence of the Thr325Ile polymorphism on procarboxypeptidase U (thrombin‐activable fibrinolysis inhibitor) activity‐based assays

V. Matus, D. Mezzano, J. Willemse, 2007, Journal of thrombosis and haemostasis : JTH.

Measurement of Procarboxypeptidase U in Human Plasma : A Laboratory Challenge

J. Willemse, D. Hendriks, 2005 .

Proline-specific peptidase activities (DPP4, PRCP, FAP and PREP) in plasma of hospitalized COVID-19 patients

I. De Meester, S. Kumar-Singh, E. Vlieghe, 2022, Clinica Chimica Acta.

Fast Homogeneous Assay for Plasma Procarboxypeptidase U

F. Goossens, Y. Kasahara, D. Hendriks, 2001, Clinical chemistry and laboratory medicine.

Molecular characterization of an extracellular acid-resistant lipase produced by Rhizopus javanicus.

G. Vriend, L. Moens, I. de Baere, 1993, Biological chemistry Hoppe-Seyler.

Chapter 295 – Carboxypeptidase U

D. Hendriks, 2013 .

242 – Carboxypeptidase U

D. Hendriks, 2004 .

SYNTHESIS OF PEPTIDYL ACETALS AS INHIBITORS OF PROLYL ENDOPEPTIDASE

A. Haemers, K. Augustyns, S. Scharpe, 1995 .

Human serum carboxypeptidase U: a new kininase?

D. Hendriks, W. Wang, S. Scharpé, 1992, Agents and actions. Supplements.

ProCPU Is Expressed by (Primary) Human Monocytes and Macrophages and Expression Differs between States of Differentiation and Activation

I. De Meester, S. Thys, D. Hendriks, 2023, International Journal of Molecular Sciences.

Release of the carboxyterminal arginine from atriopeptin II by human plasma carboxypeptidase N

G. Vanhoof, S. Scharpe, I. Meester, 1988 .

Development of a sensitive and selective assay for the determination of procarboxypeptidase U (thrombin-activatable fibrinolysis inhibitor) in plasma.

K. Augustyns, T. Olsson, S. Van Goethem, 2010, Analytical biochemistry.

Immobilized carboxypeptidase N

S. Scharpe, D. Hendriks, Wei Wang, 1994, Applied Biochemistry and Biotechnology.

Thrombin activatable fibrinolysis inhibitor (TAFI): a molecular link between coagulation and fibrinolysis.

D. Radojkovic, P. Miljić, I. Elezović, 2010, Srpski arhiv za celokupno lekarstvo.

Thrombin a ctivatable Fibrinolysis inhibitor (T a F i ): a Molecular l ink Between Coagulation and Fibrinolysis

J. Willemse, D. Hendriks, M. Čolović, 2010 .

Pleiotropic Effects of Atorvastatin Result in a Downregulation of the Carboxypeptidase U System (CPU, TAFIa, CPB2) in a Mouse Model of Advanced Atherosclerosis

L. Roth, J. Mertens, D. Hendriks, 2021, Pharmaceutics.

Carboxypeptidase U : A novel plasma carboxypeptidase with affinity for plasminogen

S. Scharpe, D. Hendriks, W. Wang, 1994 .

Comparative substrate specificity study of carboxypeptidase U (TAFIa) and carboxypeptidase N: development of highly selective CPU substrates as useful tools for assay development.

T. Olsson, J. Willemse, D. Hendriks, 2008, Clinica chimica acta; international journal of clinical chemistry.

A rapid and sensitive assay for the quantitation of carboxypeptidase N, an important regulator of inflammation.

J. Willemse, D. Hendriks, 2006, Clinica chimica acta; international journal of clinical chemistry.

Comparative study of commercially available procarboxypeptidase U (thrombin‐activatable fibrinolysis inhibitor) assays

J. Willemse, D. Hendriks, E. Heylen, 2011, Journal of thrombosis and haemostasis : JTH.

Major carboxypeptidase N deficiency.

J. Willemse, D. Hendriks, David Chen, 2008, Clinica chimica acta; international journal of clinical chemistry.

Comparative molecular modeling of the active subunit of human kininase I.

G. Vriend, M. Vingron, D. Hendriks, 1992, Agents and actions. Supplements.

Carboxypeptidase U (TAFIa): a new drug target for fibrinolytic therapy?

M. Nesheim, J. Willemse, D. Hendriks, 2009, Journal of thrombosis and haemostasis : JTH.

Lower Baseline Plasma Cortisol and Prolactin together with Increased Body Temperature and Higher mCPP-Induced Cortisol Responses in Men with Pedophilia

H. Westenberg, M. Maes, P. Cosyns, 2001, Neuropsychopharmacology.