G. K. Smith

发表

A rapid and sensitive assay for tyrosine-3-monooxygenase based upon the release of 3H2O and adsorption of [3H]-tyrosine by charcoal.

J. Reinhard, G. K. Smith, C. A. Nichol, 1986, Life sciences.

Observation of OH (υ = 0, 1) in the reactions of O(3P) with HCl (υ = 0, 1, 2)

J. Butler, M. Lin, J. W. Hudgens, 1978 .

Vibration-electronic coupling in the quenching of electronically excited alkali atoms by diatomics.

E. R. Fisher, G. K. Smith, 1971, Applied optics.

Imidazo[5,1-f][1,2,4]triazin-2-amines as novel inhibitors of polo-like kinase 1.

L. Shewchuk, T. J. Lansing, R. Mook, 2008, Bioorganic & medicinal chemistry letters.

Ready to use agarose encapsulated PCR reagents.

R. Setterquist, G. K. Smith, 1996, Nucleic acids research.

A high throughput sphingomyelinase assay.

D. Hassler, G. K. Smith, R. Laethem, 2000, Methods in enzymology.

Antibody-directed enzyme prodrug therapy with the T268G mutant of human carboxypeptidase A1: in vitro and in vivo studies with prodrugs of methotrexate and the thymidylate synthase inhibitors GW1031 and GW1843.

J. Miller, J. Humphreys, T. Blumenkopf, 1999, Bioconjugate chemistry.

Increases in neutral, Mg2+-dependent and acidic, Mg2+-independent sphingomyelinase activities precede commitment to apoptosis and are not a consequence of caspase 3-like activity in Molt-4 cells in response to thymidylate synthase inhibition by GW1843.

Y. Hannun, R. Sundseth, J. Strum, 1998, Blood.

Purification and Characterization of a Membrane Bound Neutral pH Optimum Magnesium-dependent and Phosphatidylserine-stimulated Sphingomyelinase from Rat Brain*

B. Liu, Y. Hannun, K. Weaver, 1998, The Journal of Biological Chemistry.

Synthesis and biological activity of an acyclic analogue of 5,6,7,8-tetrahydrofolic acid, N-[4-[[3-(2,4-diamino-1,6-dihydro-6-oxo-5- pyrimidinyl)propyl]amino]-benzoyl]-L-glutamic acid.

R. Ferone, M. Hanlon, M. Edelstein, 1990, Journal of medicinal chemistry.

Use of 5'-UTP-agarose for ribonuclease affinity chromatography.

K. Schray, G. K. Smith, S. Schaffer, 1978, Analytical biochemistry.

Genetically unstable CXG repeats are structurally dynamic and have a high propensity for folding. An NMR and UV spectroscopic study.

M. Zheng, X. Huang, Xueyong Yang, 1996, Journal of molecular biology.

The OH(X2Π, υ = 0) rotational energy distribution in the reaction of O(1D) + H2

J. Butler, M. Lin, G. K. Smith, 1979 .

Effect of purine synthesis inhibition on WiDr spheroids in vitro or on WiDr or colon 38 tumors in vivo. Complete growth inhibition but not regression.

J. Stables, R. Mullin, V. Knick, 1994, Biochemical pharmacology.

New inhibitors of sepiapterin reductase. Lack of an effect of intracellular tetrahydrobiopterin depletion upon in vitro proliferation of two human cell lines.

M. Edelstein, E. Bigham, G. K. Smith, 1992, The Journal of biological chemistry.

Characterization of the enzyme complex involving the folate-requiring enzymes of de novo purine biosynthesis.

S. Benkovic, W. T. Mueller, G. Wasserman, 1980, Biochemistry.

Folate analogues. 35. Synthesis and biological evaluation of 1-deaza, 3-deaza, and bridge-elongated analogues of N10-propargyl-5,8-dideazafolic acid.

R. Ferone, J. Humphreys, R. Kisliuk, 1991, Journal of medicinal chemistry.

Benzo[f]quinazoline inhibitors of thymidylate synthase: methyleneamino-linked aroylglutamate derivatives.

R. Ferone, S. Dickerson, W. Pendergast, 1994, Journal of medicinal chemistry.

Benzoquinazoline inhibitors of thymidylate synthase: enzyme inhibitory activity and cytotoxicity of some sulfonamidobenzoylglutamate and related derivatives.

R. Ferone, S. Dickerson, W. Pendergast, 1993, Journal of medicinal chemistry.

Biosynthesis and metabolism of tetrahydrobiopterin and molybdopterin.

G. K. Smith, C. A. Nichol, D. Duch, 1985, Annual review of biochemistry.

On the role of sepiapterin reductase in the biosynthesis of tetrahydrobiopterin.

G. K. Smith, 1987, Archives of biochemistry and biophysics.

Synthesis, utilization, and structure of the tetrahydropterin intermediates in the bovine adrenal medullary de novo biosynthesis of tetrahydrobiopterin.

G. K. Smith, C. A. Nichol, 1986, The Journal of biological chemistry.

Two new tetrahydropterin intermediates in the adrenal medullary de novo biosynthesis of tetrahydrobiopterin.

G. K. Smith, C. A. Nichol, 1984, Biochemical and biophysical research communications.

Tetrahydrobiopterin is synthesized by separate pathways from dihydroneopterin triphosphate and from sepiapterin in adrenal medulla preparations.

G. K. Smith, C. A. Nichol, 1983, Archives of biochemistry and biophysics.

Thienyl and thiazolyl acyclic analogues of 5-deazatetrahydrofolic acid.

R. Ferone, E. Bigham, G. K. Smith, 1994, Journal of medicinal chemistry.

Direct transfer of one-carbon units in the transformylations of de novo purine biosynthesis.

S. Benkovic, L. Slieker, W. T. Mueller, 1982, Biochemistry.

Synthesis and biological activity of open-chain analogues of 5,6,7,8-tetrahydrofolic acid--potential antitumor agents.

R. Ferone, E. Bigham, W. Mallory, 1992, Journal of medicinal chemistry.

L(-)-10-Formyltetrahydrofolate is the cofactor for glycinamide ribonucleotide transformylase from chicken liver.

S. Benkovic, P. Benkovic, G. K. Smith, 1981, Biochemistry.

Expression and characterization of human pancreatic preprocarboxypeptidase A1 and preprocarboxypeptidase A2.

T. Blumenkopf, P. Ray, G. K. Smith, 1996, Archives of biochemistry and biophysics.

OH (X 2Πi) product internal energy distribution formed in the reaction of O(1D2) with H2

J. Butler, G. K. Smith, 1980 .

Metabolic effects and kill of human T-cell leukemia by 5-deazaacyclotetrahydrofolate, a specific inhibitor of glycineamide ribonucleotide transformylase.

S. Kaufmann, G. K. Smith, D. Duch, 1992, Cancer research.

Human mononuclear phagocyte inducible nitric oxide synthase (iNOS): analysis of iNOS mRNA, iNOS protein, biopterin, and nitric oxide production by blood monocytes and peritoneal macrophages.

J. Weinberg, P. Shami, M. Misukonis, 1995, Blood.

Diagnostic probes targeting the major sperm protein gene that may be useful in the molecular identification of nematodes.

G. Fox, R. Setterquist, G. K. Smith, 1996, Journal of nematology.

Activity of an NAD-dependent 5,10-methylenetetrahydrofolate dehydrogenase in normal tissue, neoplastic cells, and oncogene-transformed cells.

R. Rigual, T. Monaco, R. Mullin, 1990, Archives of biochemistry and biophysics.

A sensitive high-performance liquid chromatographic-fluorometric assay for dihydrofolate reductase in adult rat brain, using 7,8-dihydrobiopterin as substrate.

J. Reinhard, G. K. Smith, C. A. Nichol, 1984, Analytical biochemistry.

New Antiparallel Duplex Motif of DNA CCG Repeats That Is Stabilized by Extrahelical Bases Symmetrically Located in the Minor Groove

Xiaolian Gao, G. K. Smith, M. Zheng, 1995 .

DNA CTG triplet repeats involved in dynamic mutations of neurologically related gene sequences form stable duplexes.

G. Fox, G. K. Smith, X. Gao, 1995, Nucleic acids research.

Selective reduction of seminal ribonuclease by glutathione.

G. K. Smith, S. Schaffer, 1979, Archives of biochemistry and biophysics.

On the cofactor specificity of glycinamide ribonucleotide and 5-aminoimidazole-4-carboxamide ribonucleotide transformylase from chicken liver.

S. Benkovic, W. T. Mueller, P. Benkovic, 1981, Biochemistry.

Studies on the mechanism of antitumor action of 2-desamino-2-methyl-5,8-dideazaisofolic acid.

M. Hanlon, B. Shane, J. Freisheim, 1991, Biochemical pharmacology.

Inhibition of chicken liver 5-aminoimidazole-4-carboxamide ribonucleotide transformylase by 5,8-dideaza analogues of folic acid.

S. Benkovic, W. T. Mueller, J. Hynes, 1988, Biochemical pharmacology.

The C-6 proton of tetrahydrobiopterin is acquired from water, not NADPH, during de novo biosynthesis.

G. K. Smith, C. A. Nichol, P. Chandrasurin, 1985, The Journal of biological chemistry.

Rotational and vibrational energy distributions of 16OH(X 2Π) and 18OH(X 2Π) produced in the reaction of O(1D) with H2O and H2 18O

J. Butler, G. K. Smith, L. Talley, 1981 .

Enhanced antitumor activity for the thymidylate synthase inhibitor 1843U89 through decreased host toxicity with oral folic acid.

R. Ferone, C. M. Boytos, H. R. Wilson, 1995, Cancer research.

Sequence, overproduction and purification of Vibrio proteolyticus ribosomal protein L18 for in vitro and in vivo studies.

Todd H. Oakley, G. Fox, R. Setterquist, 1996, Gene.

On the substrate specificity of bovine liver dihydrofolate reductase: new unconjugated dihydropterin substrates.

E. Bigham, G. K. Smith, C. A. Nichol, 1987, Archives of biochemistry and biophysics.

Cathepsin D is partly endocytosed by the LRP1 receptor and inhibits LRP1-regulated intramembrane proteolysis

S. Pattingre, V. Laurent-Matha, M. Beaujouin, 2012, Oncogene.

Glutathione-facilitated refolding of reduced, denatured bovine seminal ribonuclease: kinetics and characterization of products.

G. D'alessio, G. K. Smith, S. Schaffer, 1978, Biochemistry.