D. Sychantha

发表

Chemical biology of peptidoglycan acetylation and deacetylation.

P. Moynihan, A. Clarke, D. Sychantha, 2014, Bioorganic chemistry.

Accumulation of Peptidoglycan O-Acetylation Leads to Altered Cell Wall Biochemistry and Negatively Impacts Pathogenesis Factors of Campylobacter jejuni*

Michael E. Taveirne, V. DiRita, W. Vollmer, 2016, The Journal of Biological Chemistry.

In vitro characterization of the antivirulence target of Gram-positive pathogens, peptidoglycan O-acetyltransferase A (OatA)

P. Howell, H. Robinson, C. Dowson, 2017, PLoS pathogens.

Evolution-guided discovery of antibiotics that inhibit peptidoglycan remodelling

Y. Brun, Gerard D. Wright, Nicholas Waglechner, 2020, Nature.

A widespread family of bacterial gene clusters produces ClpP inhibitors

Andrew C. Pawlowski, G. Prehna, Elizabeth J. Culp, 2021 .

Assays for the Enzymes Catalyzing the O-Acetylation of Bacterial Cell Wall Polysaccharides.

A. Clarke, D. Sychantha, Ashley S Brott, 2019, Methods in molecular biology.

Molecular Basis for the Attachment of S-Layer Proteins to the Cell Wall of Bacillus anthracis.

P. Howell, G. Boons, R. Chapman, 2018, Biochemistry.

Three-Dimensional Structure and Optimization of the Metallo-β-Lactamase Inhibitor Aspergillomarasmine A

J. Britten, Gerard D. Wright, K. Koteva, 2022, ACS omega.

ClpP inhibitors are produced by a widespread family of bacterial gene clusters

Andrew C. Pawlowski, G. Wright, G. Prehna, 2022, Nature Microbiology.

Mechanistic Pathways for Peptidoglycan O-Acetylation and De-O-Acetylation

A. Clarke, D. Sychantha, Carys S. Jones, 2018, Front. Microbiol..

Suppression of β-Lactam Resistance by Aspergillomarasmine A Is Influenced by both the Metallo-β-Lactamase Target and the Antibiotic Partner

Gerard D. Wright, K. Koteva, Caitlyn M. Rotondo, 2020, Antimicrobial Agents and Chemotherapy.

An ADP-ribosyltransferase toxin kills bacterial cells by modifying structured non-coding RNAs.

J. Whitney, A. Filloux, G. Prehna, 2022, Molecular cell.

Aspergillomarasmine A inhibits metallo-β-lactamases by selectively sequestering Zn2+

Gerard D. Wright, N. Martin, K. Tehrani, 2021, The Journal of biological chemistry.

ClpP inhibitors are produced by a widespread family of bacterial gene clusters

Andrew C. Pawlowski, G. Prehna, Gerard D. Wright, 2022, Nature Microbiology.

PatB1 is an O-acetyltransferase that decorates secondary cell wall polysaccharides.

P. Howell, H. Robinson, G. Boons, 2018, Nature chemical biology.

Peptidoglycomics reveals compositional changes in peptidoglycan between biofilm- and planktonic-derived Pseudomonas aeruginosa

C. Khursigara, J. Geddes-McAlister, D. Brewer, 2019, The Journal of Biological Chemistry.

Structural basis for the O-acetyltransferase function of the extracytoplasmic domain of OatA from Staphylococcus aureus

P. Howell, A. Clarke, D. Sychantha, 2020, The Journal of Biological Chemistry.

Peptidoglycan Modification by the Catalytic Domain of Streptococcus pneumoniae OatA Follows a Ping-Pong Bi-Bi Mechanism of Action.

A. Clarke, D. Sychantha, 2018, Biochemistry.

O-acetylation of the serine-rich repeat glycoprotein GspB is coordinated with accessory Sec transport

B. Bensing, P. Sullam, R. Seepersaud, 2017, PLoS pathogens.

A feedback control mechanism governs the synthesis of lipid-linked precursors of the bacterial cell wall

P. Stansfeld, T. Bernhardt, Neil G. Greene, 2023, bioRxiv.

Allosteric inhibition of tRNA synthetase Gln4 by N-pyrimidinyl-β-thiophenylacrylamides exerts highly selective antifungal activity.

AkshatKumar Nigam, L. Cowen, Meea Fogal, 2024, Cell chemical biology.

Targeting bacterial nickel transport with aspergillomarasmine A suppresses virulence-associated Ni-dependent enzymes

K. Koteva, D. Sychantha, Gerard D Wright, 2024, Nature communications.