S. Horie

发表

Involvement of cyclooxygenase-dependent pathway in contraction of isolated ileum by urotensin II

Takeshi Saito, Y. Nomura, Y. Okuma, 2005, Peptides.

Contraction of isolated guinea-pig ileum by urotensin II via activation of ganglionic cholinergic neurons and acetylcholine release

Takeshi Saito, Y. Nomura, Y. Okuma, 2003, Neuropharmacology.

Dietary Agonists of TRPV1 Inhibit Gastric Acid Secretion in Mice

K. Terasawa, Kenjiro Matsumoto, T. Namiki, 2012, Planta Medica.

Opioid receptor agonistic characteristics of mitragynine pseudoindoxyl in comparison with mitragynine derived from Thai medicinal plant Mitragyna speciosa.

H. Takayama, K. Watanabe, N. Aimi, 1999, General pharmacology.

Quercetin-induced PC12 cell death accompanied by caspase-mediated DNA fragmentation.

Takeshi Saito, M. Kashiwayanagi, Hiroyuki Nakamura, 2007, Biological & pharmaceutical bulletin.

Mesaconitine-induced relaxation in rat aorta: role of Na+/Ca2+ exchangers in endothelial cells.

H. Takayama, T. Murayama, N. Aimi, 2004, European journal of pharmacology.

Possible role of interleukin-6 in PC12 cell death induced by MPP+ and tetrahydroisoquinoline.

Takeshi Saito, Y. Nomura, Y. Okuma, 2003, Journal of pharmacological sciences.

Vasorelaxing effect of mesaconitine, an alkaloid from Aconitum japonicum, on rat small gastric artery: possible involvement of endothelium-derived hyperpolarizing factor.

K. Boussery, J. van de Voorde, T. Murayama, 2002, Japanese Journal of Pharmacology.

Involvement of the system L amino acid transporter on uptake of S-nitroso-L-cysteine, an endogenous S-nitrosothiol, in PC12 cells.

Takeshi Saito, Y. Nomura, Y. Okuma, 2003, European journal of pharmacology.

5‐HT3 receptors promote colonic inflammation via activation of substance P/neurokinin‐1 receptors in dextran sulphate sodium‐induced murine colitis

Kenjiro Matsumoto, S. Kato, K. Amagase, 2016, British journal of pharmacology.

L-Cysteine/D,L-homocysteine-regulated ileum motility via system L and B°(,+) transporter: Modification by inhibitors of hydrogen sulfide synthesis and dietary treatments.

Kenjiro Matsumoto, Hiroyuki Nakamura, H. Fujino, 2015, European journal of pharmacology.

Stimulatory effects of nitric oxide donors on gastric acid secretion in isolated mouse stomach.

K. Watanabe, S. Yano, S. Horie, 2001, European journal of pharmacology.

Allyl Isothiocyanate, a Pungent Ingredient of Wasabi and Mustard Oil, Impairs Gastric Paracellular Barrier in Primary Cultures from the Rat Stomach via TRPA1-Independent Pathway

Kenjiro Matsumoto, S. Horie, S. Hagen, 2014 .

Stimulatory effects of centrally injected kappa-opioid receptor agonists on gastric acid secretion in urethane-anesthetized rats.

K. Watanabe, T. Murayama, S. Horie, 2001, European journal of pharmacology.

MGM-9 [(E)-methyl 2-(3-ethyl-7a,12a-(epoxyethanoxy)-9-fluoro-1,2,3,4,6,7,12,12b-octahydro-8-methoxyindolo[2,3-a]quinolizin-2-yl)-3-methoxyacrylate], a derivative of the indole alkaloid mitragynine: A novel dual-acting μ- and κ-opioid agonist with potent antinociceptive and weak rewarding effects in

M. Narita, Tsutomu Suzuki, H. Takayama, 2008, Neuropharmacology.

Partial agonistic effect of 9-hydroxycorynantheidine on mu-opioid receptor in the guinea-pig ileum.

H. Takayama, H. Ishikawa, Kenjiro Matsumoto, 2006, Life sciences.

Studies on the synthesis and opioid agonistic activities of mitragynine-related indole alkaloids: discovery of opioid agonists structurally different from other opioid ligands.

H. Takayama, H. Ishikawa, M. Kitajima, 2002, Journal of medicinal chemistry.

Neutrophil recruitment is critical for 5-fluorouracil-induced diarrhea and the decrease in aquaporins in the colon.

A. Jo, H. Sakai, M. Narita, 2014, Pharmacological research.

Possible involvement of amino acid transporters on S-nitroso-cysteine-induced inhibition of arachidonic acid release in PC12 cells

Y. Nomura, Y. Okuma, T. Murayama, 2001, Neuroscience Letters.

Juvenile social defeat stress exposure favors in later onset of irritable bowel syndrome-like symptoms in male mice

S. Ishihara, Daisuke Yamada, K. Wada, 2021, Scientific Reports.

Antisecretory effect of somatostatin on gastric acid via inhibition of histamine release in isolated mouse stomach.

T. Murayama, S. Horie, M. Komasaka, 2002, European journal of pharmacology.

Intracellular alkalinization by NH4Cl increases cytosolic Ca2+ level and tension in the rat aortic smooth muscle.

K. Watanabe, S. Yano, S. Horie, 1995, Life sciences.

Effects of hirsutine, an antihypertensive indole alkaloid from Uncaria rhynchophylla, on intracellular calcium in rat thoracic aorta.

K. Watanabe, N. Aimi, S. Yano, 1992, Life sciences.

Enhancement of phenylephrine-induced contraction in the isolated rat aorta with endothelium by H2O-extract from an Oriental medicinal plant Leonuri herba.

K. Watanabe, T. Murayama, S. Horie, 2001, Japanese journal of pharmacology.

Role of transient receptor potential melastatin 2 in surgical inflammation and dysmotility in a mouse model of postoperative ileus.

Y. Mori, H. Ozaki, M. Hori, 2018, American journal of physiology. Gastrointestinal and liver physiology.

Neurogastroenterology and Motility Role of transient receptor potential melastatin 2 in surgical inﬂammation and dysmotility in a mouse model of postoperative ileus

A. Yamamoto, H. Ozaki, M. Hori, 2018 .

Necessity of intracellular cyclic AMP in inducing gastric acid secretion via muscarinic M3 and cholecystokinin2 receptors on parietal cells in isolated mouse stomach.

S. Yano, T. Maruyama, S. Horie, 2005, Life sciences.

The rodent model of impaired gastric motility induced by allyl isothiocyanate, a pungent ingredient of wasabi, to evaluate therapeutic agents for functional dyspepsia.

Kenjiro Matsumoto, Kazuki Hashimoto, S. Horie, 2021, Journal of pharmacological sciences.

Decrease in cytosolic phospholipase A2alpha mRNA levels by reactive oxygen species via MAP kinase pathways in PC12 cells: effects of dopaminergic neurotoxins.

Takashi Saito, T. Murayama, N. Akiyama, 2005, Cellular signalling.

Reduction of SNAP25 in acid secretion defect of Foxl1-/- gastric parietal cells.

H. Koseki, Yasuo Suzuki, H. Ohno, 2004, Biochemical and biophysical research communications.

Phenolic compounds from Gastrodia rhizome and relaxant effects of related compounds on isolated smooth muscle preparation.

S. Yano, S. Horie, T. Sekine, 2002, Phytochemistry.

Chemical constituents of Aristolochia constricta: antispasmodic effects of its constituents in guinea-pig ileum and isolation of a diterpeno-lignan hybrid.

Waka Nakanishi, Waka Nakanishi, Takuya Kumamoto, 2008, Journal of natural products.

New procedure to mask the 2,3-pi bond of the indole nucleus and its application to the preparation of potent opioid receptor agonists with a Corynanthe skeleton.

H. Takayama, H. Ishikawa, M. Kitajima, 2006, Organic letters.

Inhibitory effect of mitragynine, an analgesic alkaloid from Thai herbal medicine, on neurogenic contraction of the vas deferens.

H. Takayama, Kenjiro Matsumoto, Kenjiro Matsumoto, 2005, Life sciences.

Arachidonic acid release and prostaglandin F(2alpha) formation induced by anandamide and capsaicin in PC12 cells.

T. Murayama, S. Horie, Akiyoshi Someya, 2002, European journal of pharmacology.

Inhibitory effect of mitragynine, an alkaloid with analgesic effect from Thai medicinal plant Mitragyna speciosa, on electrically stimulated contraction of isolated guinea-pig ileum through the opioid receptor.

S Yano, K. Watanabe, K Watanabe, 1997, Life sciences.

A novel method to produce extensive gastric antral ulcer in rats: Pharmacological factors involved in the etiology of antral ulceration

M. Uchida, S. Horie, M. Takayama, 1999, Journal of Physiology-Paris.

Capsaicin- and anandamide-induced gastric acid secretion via vanilloid receptor type 1 (TRPV1) in rat brain

T. Murayama, S. Horie, S. Tsuchiya, 2005, Brain Research.

Antiallergic Activity of Curcuma longa (II) : Features of inhibitory actions on histamine release from mast cells

Koichi Saito, K. Ueno, S. Yano, 2000 .

Ca2+ channel blocking effects of hirsutine, an indole alkaloid from Uncaria genus, in the isolated rat aorta.

K. Watanabe, N. Aimi, S. Yano, 1991, Planta medica.

Mesaconitine-induced relaxation in rat aorta: involvement of Ca2+ influx and nitric-oxide synthase in the endothelium.

J. van de Voorde, T. Murayama, S. Horie, 2002, European journal of pharmacology.

5-Fluorouracil Induces Diarrhea with Changes in the Expression of Inflammatory Cytokines and Aquaporins in Mouse Intestines

T. Nakagawa, H. Sakai, M. Narita, 2013, PloS one.

Dual role of serotonin in the pathogenesis of indomethacin-induced small intestinal ulceration: pro-ulcerogenic action via 5-HT3 receptors and anti-ulcerogenic action via 5-HT4 receptors.

K. Takeuchi, Kenjiro Matsumoto, S. Kato, 2012, Pharmacological research.

Differences in the morphine-induced inhibition of small and large intestinal transit: Involvement of central and peripheral μ-opioid receptors in mice.

M. Shibasaki, Tsutomu Suzuki, Tomohisa Mori, 2016, European journal of pharmacology.

Antinociceptive effect of 7-hydroxymitragynine in mice: Discovery of an orally active opioid analgesic from the Thai medicinal herb Mitragyna speciosa.

H. Takayama, H. Ishikawa, Kenjiro Matsumoto, 2004, Life sciences.

Antinociceptive constituents of Auricularia polytricha.

K. Kinoshita, M. Akiba, K. Koyama, 2002, Planta Medica.

Identification of Indole Alkaloid Structural Units Important for Stimulus-Selective TRPM8 Inhibition: SAR Study of Naturally Occurring Iboga Derivatives.

Tatsuo Watanabe, H. Takayama, M. Kitajima, 2014, Journal of natural products.

Increased Expression of 5-HT3 and NK1 Receptors in 5-Fluorouracil-Induced Mucositis in Mouse Jejunum

H. Sakai, M. Narita, Kenjiro Matsumoto, 2013, Digestive Diseases and Sciences.

Immunohistochemical co-localization of transient receptor potential vanilloid (TRPV)1 and sensory neuropeptides in the guinea-pig respiratory system

G. Michael, J. Priestley, S. Keir, 2006, Neuroscience.

Involvement of mu-opioid receptors in antinociception and inhibition of gastrointestinal transit induced by 7-hydroxymitragynine, isolated from Thai herbal medicine Mitragyna speciosa.

H. Takayama, M. Kitajima, Kenjiro Matsumoto, 2006, European journal of pharmacology.

A new indole alkaloid, 7-hydroxyspeciociliatine, from the fruits of Malaysian Mitragyna speciosa and its opioid agonistic activity

H. Takayama, M. Kitajima, N. Kogure, 2005, Journal of Natural Medicines.

Inhibitory effect of Iboga-type indole alkaloids on capsaicin-induced contraction in isolated mouse rectum

H. Takayama, M. Kitajima, Kenjiro Matsumoto, 2010, Journal of Natural Medicines.

Stimulatory effects of centrally injected nitric oxide donors on gastric acid secretion in anesthetized rats.

S. Horie, S. Tsuchiya, Kazuo Watanabe, 2002, Japanese journal of pharmacology.

Stimulatory effects of centrally injected kainate and N-methyl-d-aspartate on gastric acid secretion in anesthetized rats

S. Yano, S. Horie, S. Tsuchiya, 2001, Brain Research.

Contractile effect of TRPA1 receptor agonists in the isolated mouse intestine.

Kenjiro Matsumoto, S. Yano, S. Horie, 2007, European journal of pharmacology.

Mechanisms That Underlie μ-Opioid Receptor Agonist–Induced Constipation: Differential Involvement of μ-Opioid Receptor Sites and Responsible Regions

M. Shibasaki, Tsutomu Suzuki, Tomohisa Mori, 2013, The Journal of Pharmacology and Experimental Therapeutics.

Immunohistochemical localization of vanilloid receptor subtype 1 (TRPV1) in the guinea pig respiratory system.

G. Michael, J. Priestley, C. Page, 2005, Pulmonary pharmacology & therapeutics.

Introduction—The Genus Magnolia

F. Ikegami, S. Horie, Kazuo Watanabe, 2002 .

Involvement of glutamate and γ‐amino‐butyric acid receptor systems on gastric acid secretion induced by activation of κ‐opioid receptors in the central nervous system in rats

T. Murayama, S. Horie, S. Tsuchiya, 2003 .

Gastric acid secretion stimulated by centrally injected nociceptin in urethane-anesthetized rats.

T. Murayama, S. Horie, S. Tsuchiya, 2002, European journal of pharmacology.

Stimulatory effect of centrally injected capsaicin, an agonist of vanilloid receptors, on gastric acid secretion in rats.

K. Watanabe, T. Murayama, S. Horie, 2001, European journal of pharmacology.

Distribution of transient receptor potential cation channel subfamily V member 1-expressing nerve fibers in mouse esophagus

Kenjiro Matsumoto, T. Murayama, S. Kato, 2014, Histochemistry and Cell Biology.

Co-localization of TRPV1-expressing nerve fibers with calcitonin-gene-related peptide and substance P in fundus of rat stomach

G. Michael, J. Priestley, S. Horie, 2006, InflammoPharmacology.

Gastric Acid Secretion by Central Injection of Dynorphin A-(1 – 17), an Endogenous Ligand of κ-Opioid Receptor, in Urethane-Anesthetized Rats

T. Murayama, S. Horie, S. Tsuchiya, 2001 .

Arachidonic acid release and prostaglandin F2alpha formation induced by phenylarsine oxide in PC12 cells: possible involvement of secretory phospholipase A2 activity.

Takeshi Saito, Y. Nomura, Y. Okuma, 2002, Biochemical pharmacology.

Mesenchymal transcription factor Fkh6 is essential for the development and differentiation of parietal cells.

M. Suzuki, M. Ichinose, Y. Saito, 2001, Biochemical and biophysical research communications.

Effects of drugs acting on Cl(-)-HCO3- and Na(+)-H+ exchangers on acid secretion in the rat gastric mucosa sheet preparation.

K. Watanabe, S. Yano, S. Horie, 1992, European journal of pharmacology.

Experimental colitis alters expression of 5-HT receptors and transient receptor potential vanilloid 1 leading to visceral hypersensitivity in mice

H. Takayama, Kenjiro Matsumoto, T. Murayama, 2012, Laboratory Investigation.

Antinociception, tolerance and withdrawal symptoms induced by 7-hydroxymitragynine, an alkaloid from the Thai medicinal herb Mitragyna speciosa.

H. Takayama, H. Ishikawa, Kenjiro Matsumoto, 2005, Life sciences.

Validation of 13C-acetic acid breath test by measuring effects of loperamide, morphine, mosapride, and itopride on gastric emptying in mice.

Kenjiro Matsumoto, H. Kimura, M. Uchida, 2008, Biological & pharmaceutical bulletin.

Activation and inhibition of thermosensitive TRP channels by voacangine, an alkaloid present in Voacanga africana, an African tree.

M. Tominaga, Tatsuo Watanabe, H. Takayama, 2014, Journal of natural products.

Indole alkaloids of a Thai medicinal herb, Mitragyna speciosa, that has opioid agonistic effect in guinea-pig ileum.

H. Takayama, H. Ishikawa, Kenjiro Matsumoto, 2005, Planta medica.

Effect of mitragynine, derived from Thai folk medicine, on gastric acid secretion through opioid receptor in anesthetized rats.

H. Takayama, N. Aimi, Makiko Yamamoto, 2002, European journal of pharmacology.

Effects of synthetic sphingosine-1-phosphate analogs on arachidonic acid metabolism and cell death.

A. Nishida, Hiroyuki Nakamura, T. Murayama, 2004, Biochemical pharmacology.

Stimulatory effects of endogenous and exogenous nitric oxide on gastric acid secretion in anesthetized rats.

S. Yano, S. Horie, K. Hasebe, 2005, Nitric oxide : biology and chemistry.

Stimulatory effects of nitric oxide donors on histamine release in isolated rat gastric mucosal cells.

S. Yano, S. Horie, K. Hasebe, 2003, Biological & pharmaceutical bulletin.

Stimulatory effect of dibutyryl cyclic GMP on acid secretion in mouse isolated stomach and on histamine release in gastric mucosal cells

S. Yano, S. Horie, S. Tsuchiya, 2000, Journal of Physiology-Paris.

Inhibitory effect of N(omega)-nitro-L-arginine on gastric secretion induced by secretagogues and vagal stimulation in the isolated stomach.

S. Yano, S. Horie, K. Hasebe, 1998, European journal of pharmacology.

Neurogenic stimulation of gastric acid secretion by the Na+, K(+)-ATPase inhibitor ouabain in mouse isolated stomach.

S. Yano, T. Maruyama, S. Horie, 1996, General pharmacology.

Differential effects of Na+,K+‐ATPase inhibition by ouabain on acid secretory responses to histamine and bethanechol in the mouse isolated stomach

S. Yano, S. Horie, Kazuo Watanabe, 1994, British journal of pharmacology.

Visceral Hypersensitivity Through Transient Receptor Potential Vanilloid 1 Channels (TRPV1) in Functional Dyspepsia

Kenjiro Matsumoto, S. Horie, K. Tashima, 2018 .

Role of neuropeptide receptor systems in vanilloid VR1 receptor-mediated gastric acid secretion in rat brain.

T. Murayama, S. Horie, Akiyoshi Someya, 2004, European journal of pharmacology.

Stimulation of gastric acid secretion by progesterone metabolites as neuroactive steroids in anesthetized rats

Y. Nagakura, S. Horie, S. Tsuchiya, 2000, Journal of Physiology-Paris.

Centrally mediated inhibitory effect of 5-[2-(diethylamino)ethyl]amino-5,11-dihydro[1]benzoxepino[3,4- b]pyridine trihydrochloride (KW-5805) on gastric acid secretion in rats.

N. Yamada, M. Mizuno, S. Yano, 1990, Japanese journal of pharmacology.

Orally Active Opioid μ/δ Dual Agonist MGM-16, a Derivative of the Indole Alkaloid Mitragynine, Exhibits Potent Antiallodynic Effect on Neuropathic Pain in Mice

L. Devi, M. Narita, Tsutomu Suzuki, 2014, The Journal of Pharmacology and Experimental Therapeutics.

Neuronal Nitric Oxide Synthase-Derived Nitric Oxide Is Involved in Gastric Mucosal Hyperemic Response to Capsaicin in Rats

K. Terasawa, Kenjiro Matsumoto, T. Namiki, 2013, Pharmacology.

Role of transient receptor potential melastatin 2 (TRPM2) channels in visceral nociception and hypersensitivity

Akihiko Kato, Kenjiro Matsumoto, S. Horie, 2016, Experimental Neurology.

Immunohistochemical characterization of transient receptor potential vanilloid types 2 and 1 in a trinitrobenzene sulfonic acid-induced rat colitis model with visceral hypersensitivity

H. Yasuda, M. Kido, Kenjiro Matsumoto, 2022, Cell and Tissue Research.

Localization of TRPV1 and contractile effect of capsaicin in mouse large intestine: high abundance and sensitivity in rectum and distal colon.

J. Priestley, Kenjiro Matsumoto, T. Murayama, 2009, American journal of physiology. Gastrointestinal and liver physiology.

Protective role of vanilloid receptor type 1 in HCl‐induced gastric mucosal lesions in rats

G. Michael, J. Priestley, H. Yamamoto, 2004, Scandinavian journal of gastroenterology.

Effects of vanilloid receptor agonists and antagonists on gastric antral ulcers in rats.

H. Yamamoto, T. Murayama, S. Horie, 2001, European journal of pharmacology.

Analgesic Effects of Mitragynine and Analogs

Kenjiro Matsumoto, S. Horie, 2014 .

Subdiaphragmatic vagotomy induces a functional change in visceral Aδ primary afferent fibers in rats

M. Narita, Tsutomu Suzuki, Kenjiro Matsumoto, 2012, Synapse.

Immunohistochemical Localization of Transient Receptor Potential Vanilloid Subtype 1 in the Trachea of Ovalbumin-Sensitized Guinea Pigs

G. Michael, J. Priestley, C. Page, 2008, International Archives of Allergy and Immunology.