Guanghui Deng

发表

Design, synthesis and biological evaluation of hetero-aromatic moieties substituted pyrrole-2-carbonitrile derivatives as dipeptidyl peptidase IV inhibitors.

Hualiang Jiang, Zeng Li, Hong Liu, 2014, European journal of medicinal chemistry.

Pyrazolidine-3,5-dione derivatives as potent non-steroidal agonists of farnesoid X receptor: virtual screening, synthesis, and biological evaluation.

Kaixian Chen, Hualiang Jiang, Jianhua Shen, 2008, Bioorganic & medicinal chemistry letters.

Indole-propionic acid derivatives as potent, S1P3-sparing and EAE efficacious sphingosine-1-phosphate 1 (S1P1) receptor agonists.

J. D. Elliott, Wei Zhang, Yan Xu, 2012, Bioorganic & medicinal chemistry letters.

Simultaneous 2-O-deacetylation and 4-amination of peracetylated Neu5Ac: application to the synthesis of (4 -> 4)-piperazine derivatives linked sialic acid dimers

Hualiang Jiang, Hong Liu, Yu Zhou, 2008 .

Synthesis and biological evaluation of pyrrolidine-2-carbonitrile and 4-fluoropyrrolidine-2-carbonitrile derivatives as dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes.

Hong Liu, Jiang Wang, Y. Leng, 2013, Bioorganic & Medicinal Chemistry.

Novel complex crystal structure of prolyl hydroxylase domain-containing protein 2 (PHD2): 2,8-Diazaspiro[4.5]decan-1-ones as potent, orally bioavailable PHD2 inhibitors.

J. D. Elliott, Wei Zhang, Xichen Lin, 2013, Bioorganic & medicinal chemistry.

Tryptophan-containing dipeptide derivatives as potent PPARgamma antagonists: design, synthesis, biological evaluation, and molecular modeling.

Xiaomin Luo, Weiliang Zhu, Hualiang Jiang, 2008, European journal of medicinal chemistry.

Discovery of novel 1,2,4-thiadiazole derivatives as potent, orally active agonists of sphingosine 1-phosphate receptor subtype 1 (S1P(1)).

J. D. Elliott, Wei Zhang, Xichen Lin, 2012, Journal of medicinal chemistry.

HIGH-YIELD SYNTHESIS OF ANDROST-4-ENE-3,6,17-TRIONE AND ANDROST-4-ENE-3B,6B,17B- TRIOL

Z. Qiu, Guanghui Deng, Huyue Zhang, 2008 .

High-Yield Synthesis of Androst-4-ene-3,6,17-trione (IV) and Androst-4-ene-3β,6β,17β-triol.

Z. Qiu, Guanghui Deng, Huyue Zhang, 2008 .

Synthesis of (S)-, (R)-, and (rac)-2-amino-3,3-bis(4-fluorophenyl)propanoic acids and an evaluation of the DPP IV inhibitory activity of Denagliptin diastereomers

Hualiang Jiang, Hong Liu, Jia Li, 2008 .

Highly enantio- and diastereoselective mannich reactions of chiral Ni(II) glycinates with amino sulfones. Efficient asymmetric synthesis of aromatic alpha,beta-diamino acids.

Hualiang Jiang, Ting Shi, Hong Liu, 2008, The Journal of organic chemistry.