Silvia Cerezo-Gálvez

Discovery of beta-homophenylalanine based pyrrolidin-2-ylmethyl amides and sulfonamides as highly potent and selective inhibitors of dipeptidyl peptidase IV.

V. Matassa, M. López-Canet, P. Edwards, 2009, Bioorganic & medicinal chemistry letters.

The design of potent and selective inhibitors of DPP-4: optimization of ADME properties by amide replacements.

V. Matassa, M. López-Canet, P. Edwards, 2009, Bioorganic & medicinal chemistry letters.

From lead to preclinical candidate: optimization of beta-homophenylalanine based inhibitors of dipeptidyl peptidase IV.

V. Matassa, M. López-Canet, P. Edwards, 2009, Bioorganic & medicinal chemistry letters.

Design and Discovery of Novel, Potent Pyrazinone-Based Thrombin Inhibitors with a Solubilizing P1-P2-Linker

V. Matassa, J. Schamberger, C. Rosenbaum, 2006 .

The reversed binding of beta-phenethylamine inhibitors of DPP-IV: X-ray structures and properties of novel fragment and elaborated inhibitors.

Paul J Edwards, V. Matassa, P. Edwards, 2006, Bioorganic & medicinal chemistry letters.