Wensheng Zhang

发表

An improved water‐soluble prodrug of propofol with high molecular utilization and rapid onset of action

Yi Kang, WeiYi Zhang, Jun Yang, 2019, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Facile design of gemini surfactant-like peptide for hydrophobic drug delivery and antimicrobial activity.

Yongzhu Chen, Zhi-hua Xing, Feng Qiu, 2021, Journal of colloid and interface science.

Safety Pharmacology Study of ET-26 Hydrochloride, a Potential Drug for Intravenous General Anesthesia, in Rats and Beagle Dogs

Jin Liu, Deying Gong, Yingying Jiang, 2021, Frontiers in Pharmacology.

Preclinical safety evaluation of ET‐26 hydrochloride, a novel intravenous anesthetic agent, in beagle dogs

Jin Liu, Deying Gong, C. Deng, 2019, Journal of applied toxicology : JAT.

Metabolite‐inactive etomidate analogues alleviating suppression on adrenal function in Beagle dogs

Jin Liu, Linghui Yang, Yi Kang, 2017, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

New insights for screening etomidate analogues in the human H295R cell model.

Jin Liu, Deying Gong, Bowen Ke, 2020, Toxicology in vitro : an international journal published in association with BIBRA.

Novel compound LL-a produces long and nociceptive-selective regional anesthesia via TRPV1 channels in rodents sciatic nerve block model

Cheng Zhou, Linghui Yang, Deying Gong, 2020, Regional Anesthesia & Pain Medicine.

Emulsified Isoflurane Produces Cardiac Protection After Ischemia-Reperfusion Injury in Rabbits

Yan-Lin Wang, Jin Liu, Wensheng Zhang, 2008, Anesthesia and analgesia.

Efficacy and Safety of Fospropofol Disodium for Injection in General Anesthesia Induction for Adult Patients: A Phase 3 Trial

Chaoran Wu, Jin Liu, Wensheng Zhang, 2021, Frontiers in Pharmacology.

Comparison of Minimum Alveolar Concentration between Intravenous Isoflurane Lipid Emulsion and Inhaled Isoflurane in Dogs

Xiao-lin Yang, Wensheng Zhang, Jin Liu, 2006, Anesthesiology.

Transplantation of NSCs with OECs alleviates neuropathic pain associated with NGF downregulation in rats following spinal cord injury

Jia Liu, Xin-Fu Zhou, Jin Liu, 2013, Neuroscience Letters.

Janus particles self-assembled from a small organic atypical asymmetric gemini surfactant.

Junyang Liu, Jiahong Li, Linghui Yang, 2017, Chemical communications.

Quaternary Lidocaine Derivatives: Past, Present, and Future

Jin Liu, Wensheng Zhang, Yujun Zhang, 2021, Drug design, development and therapy.

Lido-OH, a Hydroxyl Derivative of Lidocaine, Produced a Similar Local Anesthesia Profile as Lidocaine With Reduced Systemic Toxicities

Bowen Ke, WeiYi Zhang, Wensheng Zhang, 2021, Frontiers in Pharmacology.

Correction: The quaternary lidocaine derivative QX-314 in combination with bupivacaine for long-lasting nerve block: Efficacy, toxicity, and the optimal formulation in rats

Q. Zheng, Wensheng Zhang, Tao Zhu, 2017, PloS one.

Effects of Liposomes Charge on Extending Sciatic Nerve Blockade of N-ethyl Bromide of Lidocaine in Rats

Yu Nie, Ping Feng, Yi Kang, 2016, Scientific Reports.

OECs transplantation results in neuropathic pain associated with BDNF regulating ERK activity in rats following cord hemisection

Linghui Yang, Jin Liu, Ting-hua Wang, 2013, BMC Neuroscience.

Minimum infusion rate and adrenocortical function after continuous infusion of the novel etomidate analog ET-26-HCl in rats

Jun Yang, Bin Wang, Jin Liu, 2017, PeerJ.

Structural Modification in Anesthetic Drug Development for Prodrugs and Soft Drugs

Jin Liu, C. Deng, Wensheng Zhang, 2022, Frontiers in Pharmacology.

Determination of HX0969w in Rabbit Whole Blood by Liquid Chromatography—Tandem Mass Spectrometry and its Application in a Pharmacokinetic Study

W. Yin, Yi Kang, Jun Yang, 2011, European journal of mass spectrometry.

QX‐OH/Levobupivacaine: Fixed‐dose combination to provide a long‐acting postoperative pain of knee surgery in rodents

Jin Liu, Jun Yang, Wensheng Zhang, 2018, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Efficacy and Safety of FospropofolFD Compared to Propofol When Given During the Induction of General Anaesthesia: A Phase II, Multi‐centre, Randomized, Parallel‐Group, Active‐Controlled, Double‐Blind, Double‐Dummy Study

J. Xu, Jin Liu, Wensheng Zhang, 2016, Basic & clinical pharmacology & toxicology.

An HPLC tandem mass spectrometry for quantification of ET‐26‐HCl and its major metabolite in plasma and application to a pharmacokinetic study in rats

Zhijun Wang, Xuehua Jiang, Ling Wang, 2018, Journal of pharmaceutical and biomedical analysis.

LC–MS/MS method for preclinical pharmacokinetic study of QX‐OH, a novel long‐acting local anesthetic, in sciatic nerve blockade in rats

Jin Liu, Q. Zheng, Deying Gong, 2017, Journal of pharmaceutical and biomedical analysis.

Cardioprotection afforded by St Thomas solution is enhanced by emulsified isoflurane in an isolated heart ischemia reperfusion injury model in rats.

Jin Liu, Shanling Liu, Wensheng Zhang, 2010, Journal of cardiothoracic and vascular anesthesia.

Protective effects of emulsified isoflurane after myocardial ischemia-reperfusion injury and its mechanism in rabbits.

Yan-Lin Wang, Jin Liu, Wensheng Zhang, 2009, Chinese journal of traumatology = Zhonghua chuang shang za zhi.

The Interaction Between Emulsified Isoflurane and Lidocaine Is Synergism in Intravenous Regional Anesthesia in Rats

Cheng Zhou, Jin Liu, Wensheng Zhang, 2011, Anesthesia and Analgesia.

Emulsified Isoflurane Increases Convulsive Thresholds of Lidocaine and Produces Neural Protection After Convulsion in Rats

Cheng Zhou, Jin Liu, Wensheng Zhang, 2014, Anesthesia and analgesia.

Minimum infusion rates and recovery times from different durations of continuous infusion of fospropofol, a prodrug of propofol, in rabbits: a comparison with propofol emulsion.

Min Tang, Jin Liu, Ying Yang, 2012, Veterinary anaesthesia and analgesia.

An Improved Design of Water-Soluble Propofol Prodrugs Characterized by Rapid Onset of Action

Yi Kang, Jun Yang, Jin Liu, 2014, Anesthesia and analgesia.

TEST OF THE PRODRUGS BIOCONVERSION IN RAT PLASMA , RHESUS MONKEY PLASMA , AND RAT HEPATIC MICROSOMES Hydrolysis in Rat Plasma and in Rhesus Monkey Plasma

Yi Kang, Jun Yang, Jin Liu, 2014 .

Self-assembling Peptides in Current Nanomedicine: Versatile Nanomaterials for Drug Delivery.

Fei Peng, Wensheng Zhang, Feng Qiu, 2019, Current medicinal chemistry.

QX-OH/Levobupivacaine: A Structurally Novel, Potent Local Anesthetic Produces Fast-Onset and Long-Lasting Regional Anesthesia in Rats

Cheng Zhou, Wensheng Zhang, D. Liao, 2022, Journal of pain research.

ET-26 hydrochloride (ET-26 HCl) has similar hemodynamic stability to that of etomidate in normal and uncontrolled hemorrhagic shock (UHS) rats

Jin Liu, Linghui Yang, Jun Yang, 2017, PloS one.

Safety, tolerability, and pharmacokinetics of adamgammadex sodium, a novel agent to reverse the action of rocuronium and vecuronium, in healthy volunteers.

Jin Liu, Shunju Xiang, Yingying Jiang, 2019, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

The Preclinical Pharmacological Study of a Novel Long-Acting Local Anesthetic, a Fixed-Dose Combination of QX-OH/Levobupivacaine, in Rats

Deying Gong, Yi Kang, Jin Liu, 2019, Front. Pharmacol..

High-Loading Self-Assembling Peptide Nanoparticles as a Lipid-Free Carrier for Hydrophobic General Anesthetics

Feng Qiu, Deying Gong, Yi Kang, 2021, International journal of nanomedicine.

Non‐clinical single‐ and repeated‐dose toxicity studies of ET‐26 hydrochloride in rats

Jin Liu, Deying Gong, C. Deng, 2020, Journal of applied toxicology : JAT.

Preclinical pharmacokinetics study of a novel intravenous anesthetic ET-26 hydrochloride.

Jin Liu, Deying Gong, C. Deng, 2019, Current drug metabolism.

The etomidate analog ET-26 HCl retains superior myocardial performance: Comparisons with etomidate in vivo and in vitro

Cheng Zhou, Jin Liu, Linghui Yang, 2018, PloS one.

An Etomidate Analogue With Less Adrenocortical Suppression, Stable Hemodynamics, and Improved Behavioral Recovery in Rats

Linghui Yang, Yi Kang, Jun Yang, 2017, Anesthesia and analgesia.

Evaluation of the cardiotoxicity and resuscitation of rats of a newly developed mixture of a QX-314 analog and levobupivacaine

Linghui Yang, Bowen Ke, Jin Liu, 2017, Journal of pain research.

The 14‐day repeated‐dose toxicity study of a fixed‐dose combination, QXOH/levobupivacaine, via subcutaneous injection in beagle dogs

Jin Liu, Deying Gong, Yi Kang, 2020, Journal of applied toxicology : JAT.

Efficacy and safety of ciprofol for the sedation/anesthesia in patients undergoing colonoscopy: Phase IIa and IIb multi-center clinical trials.

Jun Li, S. Yao, W. Ouyang, 2021, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Effects of intravenous bolus injection of emulsified isoflurane on QTc interval of healthy volunteers in Pharmacokinetics study.

J. Xu, Jin Liu, Wensheng Zhang, 2014, Pakistan journal of pharmaceutical sciences.

Pharmacologic studies on ET‐26 hydrochloride in a rat model of lipopolysaccharide‐induced sepsis

Jin Liu, Jun Yang, Bin Wang, 2017, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Etomidate-Induced Myoclonus in Sprague-Dawley Rats Involves Neocortical Glutamate Accumulation and N-Methyl-d-Aspartate Receptor Activity.

Yi Kang, Wensheng Zhang, Ping Liao, 2022, Anesthesia and analgesia.

E161111 is an ultra-short-acting etomidate analogue with stable haemodynamics that elicits only slight adrenocortical suppression in rats

Deying Gong, Yi Kang, Jun Yang, 2022, PeerJ.

The 14‐day repeated‐dose toxicity studies of a fixed‐dose combination, QXOH/levobupivacaine, via subcutaneous injection in mice

Jin Liu, Deying Gong, C. Deng, 2021, Journal of applied toxicology : JAT.

Addition of dexmedetomidine to QX-314 enhances the onset and duration of sciatic nerve block in rats.

Jin Liu, Linghui Yang, Wensheng Zhang, 2018, Canadian journal of physiology and pharmacology.

A Fixed-Dose Combination, QXOH/Levobupivacaine, Produces Long-Acting Local Anesthesia in Rats Without Additional Toxicity

Deying Gong, Bowen Ke, Jun Yang, 2019, Frontiers in Pharmacology.

QX‐OH, a QX‐314 derivative agent, produces long‐acting local anesthesia in rats

Jin Liu, Linghui Yang, Jun Yang, 2017, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

The quaternary lidocaine derivative QX-314 in combination with bupivacaine for long-lasting nerve block: Efficacy, toxicity, and the optimal formulation in rats

Q. Zheng, Wensheng Zhang, Tao Zhu, 2017, PloS one.

Polymerized placenta hemoglobin attenuates ischemia/reperfusion injury and restores the nitroso-redox balance in isolated rat heart.

Jin Liu, Wei Wu, Jing Li, 2009, Free radical biology & medicine.

An adaptive video shot segmentation scheme based on dual-detection model

Jin Liu, Xinghao Jiang, Tanfeng Sun, 2013, Neurocomputing.

An Video Shot Segmentation Scheme Based on Adaptive Binary Searching and SIFT

Jin Liu, Xinghao Jiang, Tanfeng Sun, 2011, ICIC.

Effect of volatile anesthetics on mortality and clinical outcomes in patients undergoing coronary artery bypass grafting: a meta-analysis of randomized clinical trials.

Jin Liu, Wensheng Zhang, Lei Yang, 2020, Minerva anestesiologica.

Amyloid-like staining property of RADA16-I nanofibers and its potential application in detecting and imaging the nanomaterial

Yujun Zhang, Yongzhu Chen, Feng Qiu, 2018, International journal of nanomedicine.