Liang-Chieh Chen

发表

O-methylated flavonol as a multi-kinase inhibitor of leukemogenic kinases exhibits a potential treatment for acute myeloid leukemia.

Chia-Ron Yang, S. Pan, Yi-Wen Wu, 2022, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Synthesis and Biological Evaluation of ortho‐Aryl N‐Hydroxycinnamides as Potent Histone Deacetylase (HDAC) 8 Isoform‐Selective Inhibitors

Yi-Ching Wang, W. Hou, Tai-Lin Lee, 2012, ChemMedChem.

Total Synthesis of Hispidulin and the Structural Basis for Its Inhibition of Proto-oncogene Kinase Pim-1.

Wei-Jan Huang, Shi-Wei Chao, Chung-I Chang, 2015, Journal of natural products.

Identification of a dual TAOK1 and MAP4K5 inhibitor using a structure-based virtual screening approach

Chia-Ron Yang, S. Pan, Wei-Jan Huang, 2020, Journal of enzyme inhibition and medicinal chemistry.

Cerebellar α6‐subunit‐containing GABAA receptors: a novel therapeutic target for disrupted prepulse inhibition in neuropsychiatric disorders

W. Sieghart, T. Nabeshima, Wei-Jan Huang, 2018, British journal of pharmacology.

Total Synthesis and Metabolic Stability of Hispidulin and Its d-Labelled Derivative

Wei-Jan Huang, K. Hsu, L. Chiou, 2017, Molecules.

Identification of a dual FLT3 and MNK2 inhibitor for acute myeloid leukemia treatment using a structure-based virtual screening approach.

J. Hsieh, S. Pan, Han-Li Huang, 2022, Bioorganic chemistry.

Investigation of Selected Flavonoid Derivatives as Potent FLT3 Inhibitors for the Potential Treatment of Acute Myeloid Leukemia.

S. Pan, Han-Li Huang, Yi-Wen Wu, 2021, Journal of natural products.

Acetylcholinesterase inhibitory activity and neuroprotection in vitro, molecular docking, and improved learning and memory functions of demethylcurcumin in scopolamine-induced amnesia ICR mice.

Chuan-Hsiao Han, W. Hou, Tai-Lin Lee, 2020, Food & function.

A novel dual HDAC and HSP90 inhibitor, MPT0G449, downregulates oncogenic pathways in human acute leukemia in vitro and in vivo

Chia-Ron Yang, S. Pan, Yi-Wen Wu, 2021, Oncogenesis.

Biological Evaluation of Selected Flavonoids as Inhibitors of MNKs Targeting Acute Myeloid Leukemia.

S. Pan, Han-Li Huang, Yi-Wen Wu, 2020, Journal of natural products.

Discovery of aliphatic-chain hydroxamates containing indole derivatives with potent class I histone deacetylase inhibitory activities.

J. Guh, Wei-Jan Huang, Shi-Wei Chao, 2018, European journal of medicinal chemistry.

Design of Diarylheptanoid Derivatives as Dual Inhibitors Against Class IIa Histone Deacetylase and β-amyloid Aggregation

W. Hou, Wei-Jan Huang, K. Hsu, 2018, Front. Pharmacol..

Synthesis and biological evaluation of acridine-based histone deacetylase inhibitors as multitarget agents against Alzheimer's disease.

S. Pan, Chih-Jou Su, Wei-Jan Huang, 2020, European journal of medicinal chemistry.

Synthesis and biological evaluation of C-4 substituted phenoxazine-bearing hydroxamic acids with potent class II histone deacetylase inhibitory activities

Sung-Bau Lee, Wei-Jan Huang, K. Hsu, 2023, Journal of enzyme inhibition and medicinal chemistry.

Inhibition of Acetylcholinesterase and Amyloid-β Aggregation by Piceatannol and Analogs: Assessing In Vitro and In Vivo Impact on a Murine Model of Scopolamine-Induced Memory Impairment

Mei-Hsien Lee, W. Hou, Yingyu Sie, 2023, Antioxidants.