M. Skelton

发表

Effects of developmental manganese, stress, and the combination of both on monoamines, growth, and corticosterone

M. Aschner, C. Vorhees, MichaelT . Williams, 2014, Toxicology reports.

Creatine transporter deficiency leads to increased whole body and cellular metabolism

G. Pyne-Geithman, Z. Khuchua, J. Clark, 2016, Amino Acids.

Effect of a neurotoxic dose regimen of (+)-methamphetamine on behavior, plasma corticosterone, and brain monoamines in adult C57BL/6 mice.

C. Vorhees, MichaelT . Williams, T. Schaefer, 2010, Neurotoxicology and teratology.

(+)‐Methamphetamine increases corticosterone in plasma and BDNF in brain more than forced swim or isolation in neonatal rats

C. Vorhees, MichaelT . Williams, T. Schaefer, 2008, Synapse.

Cognitive impairments from developmental exposure to serotonergic drugs: citalopram and MDMA.

C. Vorhees, MichaelT . Williams, T. Schaefer, 2013, The international journal of neuropsychopharmacology.

Treatment with MDMA from P11–20 disrupts spatial learning and path integration learning in adolescent rats but only spatial learning in older rats

C. Vorhees, MichaelT . Williams, M. Skelton, 2006, Psychopharmacology.

Targeted therapies for hepatocellular carcinoma.

B. O'Neil, M. Skelton, 2008, Clinical advances in hematology & oncology : H&O.

Comparison of the developmental effects of 5-methoxy-N,N-diisopropyltryptamine (Foxy) to (±)-3,4-methylenedioxymethamphetamine (ecstasy) in rats

C. Vorhees, MichaelT . Williams, T. Schaefer, 2009, Psychopharmacology.

Metyrapone attenuates the sequential learning deficits but not monoamine depletions following d,l‐fenfluramine administration to adult rats

C. Vorhees, MichaelT . Williams, G. Gudelsky, 2004, Synapse.

Dodecyl creatine ester-loaded nanoemulsion as a promising therapy for creatine transporter deficiency.

J. Benoit, A. Pruvost, S. Dézard, 2019, Nanomedicine.

Creatine transporter (Slc6a8) knockout mice show an inattentive-like phenotype in the 5-choice serial reaction time test

M. Skelton, Rosalyn Liou, Marla K. Perna, 2022, bioRxiv.

Creatine transporter (SLC6A8) knockout mice display an increased capacity for in vitro creatine biosynthesis in skeletal muscle

A. Russell, S. Lamon, R. Snow, 2014, Front. Physiol..

Comparison of time-dependent effects of (+)-methamphetamine or forced swim on monoamines, corticosterone, glucose, creatine, and creatinine in rats

C. Vorhees, MichaelT . Williams, P. Tang, 2008, BMC Neuroscience.

Creatine Transporter (CrT; Slc6a8) Knockout Mice as a Model of Human CrT Deficiency

Joseph F. Clark, C. Vorhees, MichaelT . Williams, 2011, PloS one.

Creatine Transporter, Reduced in Colon Tissues From Patients With Inflammatory Bowel Diseases, Regulates Energy Balance in Intestinal Epithelial Cells, Epithelial Integrity, and Barrier Function.

S. Colgan, E. Murphy, M. Gerich, 2020, Gastroenterology.

Secondary tumours following etoposide containing therapy for germ cell cancer.

C. Boshoff, J. Ong, G. Rustin, 1995, Annals of oncology : official journal of the European Society for Medical Oncology.

Neurological deficits and glycosphingolipid accumulation in saposin B deficient mice

Xianlin Han, Ying Sun, C. Vorhees, 2008, Human molecular genetics.

A case of oxaliplatin-related posterior reversible encephalopathy syndrome.

R. Goldberg, B. O'Neil, M. Skelton, 2007, Clinical colorectal cancer.

Dodecyl Creatine Ester Improves Cognitive Function and Identifies Drivers of Creatine Deficiency

R. Hamoudi, J. Armengaud, L. Baroncelli, 2022, bioRxiv.

Neuronopathic Gaucher disease in the mouse: viable combined selective saposin C deficiency and mutant glucocerebrosidase (V394L) mice with glucosylsphingosine and glucosylceramide accumulation and progressive neurological deficits

Ying Sun, Y. Hannun, C. Vorhees, 2010, Human molecular genetics.

Specific saposin C deficiency: CNS impairment and acid β-glucosidase effects in the mouse

Ying Sun, Y. Hannun, C. Vorhees, 2009, Human molecular genetics.

Effects of inhibiting neonatal methamphetamine-induced corticosterone release in rats by adrenal autotransplantation on later learning, memory, and plasma corticosterone levels

C. Vorhees, T. Schaefer, D. Graham, 2010, International Journal of Developmental Neuroscience.

Neonatal +-methamphetamine exposure in rats alters adult locomotor responses to dopamine D1 and D2 agonists and to a glutamate NMDA receptor antagonist, but not to serotonin agonists.

C. Vorhees, T. Schaefer, A. A. Braun, 2013, The international journal of neuropsychopharmacology.

In Utero and Lactational Exposure to PCBs in Mice: Adult Offspring Show Altered Learning and Memory Depending on Cyp1a2 and Ahr Genotypes

C. Vorhees, D. Nebert, T. Schaefer, 2011, Environmental health perspectives.

Periadolescent rats (P41-50) exhibit increased susceptibility to D-methamphetamine-induced long-term spatial and sequential learning deficits compared to juvenile (P21-30 or P31-40) or adult rats (P51-60).

Sandra L. Wood, C. Vorhees, A. Mccrea, 2005, Neurotoxicology and teratology.

Protein tyrosine phosphatase alpha (PTPα) knockout mice show deficits in Morris water maze learning, decreased locomotor activity, and decreases in anxiety

T. Doetschman, C. Vorhees, C. Pallen, 2003, Brain Research.

Effects of (+)-methamphetamine on path integration and spatial learning, but not locomotor activity or acoustic startle, align with the stress hyporesponsive period in rats

C. Vorhees, T. Schaefer, A. A. Braun, 2009, International Journal of Developmental Neuroscience.

Effects of neonatal (+)-methamphetamine on path integration and spatial learning in rats: effects of dose and rearing conditions

C. Vorhees, T. Schaefer, N. Herring, 2008, International Journal of Developmental Neuroscience.

Age-dependent effects of neonatal methamphetamine exposure on spatial learning

C. Vorhees, M. Skelton, M. T. Williams, 2007, Behavioural pharmacology.

Blueberry Supplementation in Midlife for Dementia Risk Reduction

R. Krikorian, P. Sullivan, S. Summer, 2022, Nutrients.

Comparison of (+)‐methamphetamine, ±‐Methylenedioxymethamphetamine, (+)‐amphetamine and ±‐fenfluramine in rats on egocentric learning in the Cincinnati water maze

C. Vorhees, T. Schaefer, A. A. Braun, 2011, Synapse.

Intranasal carnosine attenuates transcriptomic alterations and improves mitochondrial function in the Thy1-aSyn mouse model of Parkinson's disease.

M. Genter, M. Skelton, Mei-Ling Bermúdez, 2018, Molecular genetics and metabolism.

(+/–)3,4-Methylenedioxymethamphetamine (MDMA) Dose-Dependently Impairs Spatial Learning in the Morris Water Maze after Exposure of Rats to Different Five-Day Intervals from Birth to Postnatal Day Twenty

C. Vorhees, T. Schaefer, N. Herring, 2009, Developmental Neuroscience.

Prenatal immune challenge in rats: effects of polyinosinic-polycytidylic acid on spatial learning, prepulse inhibition, conditioned fear, and responses to MK-801 and amphetamine.

C. Vorhees, T. Schaefer, A. A. Braun, 2015, Neurotoxicology and teratology.

Developmental manganese neurotoxicity in rats: Cognitive deficits in allocentric and egocentric learning and memory.

C. Vorhees, R. Amos-Kroohs, Laurie L. Davenport, 2017, Neurotoxicology and teratology.

Developmental effects of 3,4-methylenedioxymethamphetamine: a review

C. Vorhees, M. Skelton, M. T. Williams, 2008, Behavioural pharmacology.

Exposure to 3,4-methylenedioxymethamphetamine (MDMA) on postnatal days 11–20 induces reference but not working memory deficits in the Morris water maze in rats: implications of prior learning

Charles V. Vorhees, C. Vorhees, Michael T. Williams, 2004, International Journal of Developmental Neuroscience.

Neonatal (+)-methamphetamine increases brain derived neurotrophic factor, but not nerve growth factor, during treatment and results in long-term spatial learning deficits

C. Vorhees, T. Schaefer, M. Skelton, 2007, Psychoneuroendocrinology.

Male mice placed on a ketogenic diet from postnatal day (P) 21 through adulthood have reduced growth, are hypoactive, show increased freezing in a conditioned fear paradigm, and have spatial learning deficits

M. Skelton, Keila N. Miles, 2020, Brain Research.

Short‐ and long‐term effects of (+)‐methamphetamine and (±)‐3,4‐methylenedioxymethamphetamine on monoamine and corticosterone levels in the neonatal rat following multiple days of treatment

C. Vorhees, T. Schaefer, N. Herring, 2008, Journal of neurochemistry.

Phosphodiesterase-1b (Pde1b) knockout mice are resistant to forced swim and tail suspension induced immobility and show upregulation of Pde10a

C. Vorhees, R. Duman, J. R. Hufgard, 2017, Psychopharmacology.

Developmental stress and lead (Pb): Effects of maternal separation and/or Pb on corticosterone, monoamines, and blood Pb in rats.

C. Vorhees, T. Schaefer, A. A. Braun, 2016, Neurotoxicology.

Dodecyl creatine ester improves cognitive function and identifies key protein drivers including KIF1A and PLCB1 in a mouse model of creatine transporter deficiency

R. Hamoudi, J. Armengaud, L. Baroncelli, 2023, Frontiers in Molecular Neuroscience.

Expression and distribution of creatine transporter and creatine kinase (brain isoform) in developing and mature rat cochlear tissues

P. Thorne, Sailakshmi Velamoor, Ann C. Y. Wong, 2012, Histochemistry and Cell Biology.

Effects of developmental stress and lead (Pb) on corticosterone after chronic and acute stress, brain monoamines, and blood Pb levels in rats

C. Vorhees, P. Tang, T. Schaefer, 2011, International Journal of Developmental Neuroscience.

(±)-3,4-Methylenedioxymethamphetamine treatment in adult rats impairs path integration learning: A comparison of single vs once per week treatment for 5 weeks

C. Vorhees, T. Schaefer, N. Herring, 2008, Neuropharmacology.

Alterations in Body Temperature, Corticosterone, and Behavior Following the Administration of 5-Methoxy-Diisopropyltryptamine (‘Foxy’) to Adult Rats: a New Drug of Abuse

C. Vorhees, T. Schaefer, J. Lipton, 2007, Neuropsychopharmacology.

Comparison of the elevated plus and elevated zero mazes in treated and untreated male Sprague–Dawley rats: Effects of anxiolytic and anxiogenic agents

C. Vorhees, A. A. Braun, M. Skelton, 2011, Pharmacology Biochemistry and Behavior.

Absorption and clearance of +/-3,4-methylenedioxymethamphetamine from the plasma of neonatal rats.

C. Vorhees, A. Vinks, M. Skelton, 2004, Neurotoxicology and teratology.

Neonatal citalopram treatment inhibits the 5-HT depleting effects of MDMA exposure in rats.

C. Vorhees, T. Schaefer, D. Graham, 2012, ACS chemical neuroscience.

Deletion of the Creatine Transporter (Slc6a8) in Dopaminergic Neurons Leads to Hyperactivity in Mice

K. Seroogy, K. Lundgren, M. Skelton, 2019, Journal of Molecular Neuroscience.

Cognitive deficits and increases in creatine precursors in a brain‐specific knockout of the creatine transporter gene Slc6a8

C. Vorhees, M. T. Williams, A. Mabondzo, 2018, Genes, brain, and behavior.

Cognitive deficits and increases in creatine precursors in a brain-specific knockout of the creatine transporter gene Slc6a8

C. Vorhees, A. Mabondzo, M. Skelton, 2017, bioRxiv.

Prenatal immune challenge in rats: Altered responses to dopaminergic and glutamatergic agents, prepulse inhibition of acoustic startle, and reduced route‐based learning as a function of maternal body weight gain after prenatal exposure to poly IC

C. Vorhees, T. Schaefer, A. A. Braun, 2012, Synapse.

A heterozygous mutation in tubulin, beta 2B ( Tubb2b ) causes cognitive deficits and hippocampal disorganization

C. Vorhees, A. Driver, R. Stottmann, 2017, Genes, brain, and behavior.

Creatine transporter deficiency leads to increased whole body and cellular metabolism

Joseph F. Clark, G. Pyne-Geithman, Z. Khuchua, 2016, Amino Acids.

Learning and memory after neonatal exposure to 3,4‐methylenedioxymethamphetamine (ecstasy) in rats: Interaction with exposure in adulthood

C. Vorhees, M. A. Cohen, T. Schaefer, 2005, Synapse.

Dopamine depletion in either the dorsomedial or dorsolateral striatum impairs egocentric Cincinnati water maze performance while sparing allocentric Morris water maze learning

C. Vorhees, K. Seroogy, A. A. Braun, 2015, Neurobiology of Learning and Memory.

Neuronal reorganization in adult rats neonatally exposed to (±)-3,4-methylenedioxymethamphetamine

C. Vorhees, A. Maple, Russell W. Brown, 2014, Toxicology reports.

Distinct periods of developmental sensitivity to the effects of 3,4-(±)-methylenedioxymethamphetamine (MDMA) on behaviour and monoamines in rats.

C. Vorhees, T. Schaefer, A. A. Braun, 2012, The international journal of neuropsychopharmacology.

Effects of periadolescent fluoxetine and paroxetine on elevated plus-maze, acoustic startle, and swimming immobility in rats while on and off-drug

C. Vorhees, D. Graham, M. Skelton, 2011, Behavioral and Brain Functions.

Deciphering neuronal deficit and protein profile changes in human brain organoids from patients with creatine transporter deficiency

R. Hamoudi, J. Armengaud, Á. Apáti, 2023, bioRxiv.

Deletion of the creatine transporter gene in neonatal, but not adult, mice leads to cognitive deficits

Marla K. Perna, M. Skelton, A. N. Kokenge, 2019, Journal of inherited metabolic disease.

Intranasal carnosine attenuates transcriptomic alterations and improves mitochondrial function in the Thy1-aSyn mouse model of Parkinson's disease.

M. Genter, M. Skelton, Mei-Ling Bermúdez, 2018, Molecular genetics and metabolism.

Creatine transporter knockout mice (Slc6a8) show increases in serotonin-related proteins and are resilient to learned helplessness

A. Gutierrez, M. Skelton, Zuhair I. Abdulla, 2019, Behavioural Brain Research.

Dopamine depletion in either the dorsomedial or dorsolateral striatum impairs egocentric Cincinnati water maze performance while sparing allocentric Morris water maze learning

C. Vorhees, K. Seroogy, A. A. Braun, 2015, Neurobiology of Learning and Memory.

Expression and distribution of creatine transporter and creatine kinase (brain isoform) in developing and mature rat cochlear tissues

P. Thorne, Sailakshmi Velamoor, Ann C. Y. Wong, 2012, Histochemistry and Cell Biology.

A Gad2 specific Slc6a8 deletion recapitulates the contextual and cued freezing deficits seen in Slc6a8-/y mice

C. Vorhees, M. Skelton, Rosalyn Liou, 2023, Brain Research.

Female mice heterozygous for creatine transporter deficiency show moderate cognitive deficits

C. Vorhees, M. Skelton, Michael T. Williams, 2014, Journal of Inherited Metabolic Disease.

Deletion of the creatine transporter gene in neonatal, but not adult, mice lead to cognitive deficits

Marla K. Perna, M. Skelton, Zuhair I. Abdulla, 2019, bioRxiv.