Satyamaheshwar Peddibhotla

发表

Inhibition of Protein Kinase C-Driven Nuclear Factor-κB Activation: Synthesis, Structure−Activity Relationship, and Pharmacological Profiling of Pathway Specific Benzimidazole Probe Molecules

John Calvin Reed, J. Cashman, G. Roth, 2010, Journal of medicinal chemistry.

β-Arrestin-Biased Allosteric Modulator of NTSR1 Selectively Attenuates Addictive Behaviors

W. Wetsel, M. Caron, A. Badea, 2020, Cell.

Sensitization of tumor cells toward chemotherapy: enhancing the efficacy of camptothecin with imidazolines.

Theresa A Lansdell, J. Tepe, Satyamaheshwar Peddibhotla, 2004, Chemistry & biology.

Simultaneous arming and structure/activity studies of natural products employing O-H insertions: an expedient and versatile strategy for natural products-based chemical genetics.

Jun O. Liu, Yongjun Dang, D. Romo, 2007, Journal of the American Chemical Society.

Synthesis and physicochemical characterization of novel phenotypic probes targeting the nuclear factor-kappa B signaling pathway

John Calvin Reed, G. Roth, R. G. Correa, 2013, Beilstein journal of organic chemistry.

Identification of Inhibitors of NOD1-Induced Nuclear Factor-κB Activation

John Calvin Reed, Brock T Brown, G. Roth, 2011, ACS medicinal chemistry letters.

Sensitization of cancer cells to DNA damaging agents by imidazolines.

J. Tepe, Satyamaheshwar Peddibhotla, Vasudha Sharma, 2006, Journal of the American Chemical Society.

Optimization of a Urea-containing Series of Nicotinamide Phosphoribosyltransferase (NAMPT) Activators.

M. Jackson, E. Sergienko, S. Gardell, 2021, Bioorganic & medicinal chemistry letters.

3-Substituted-3-hydroxy-2-oxindole, an Emerging New Scaffold for Drug Discovery with Potential Anti-Cancer and other Biological Activities

Satyamaheshwar Peddibhotla, 2009 .

Mild arming and derivatization of natural products via an In(OTf)3-catalyzed arene iodination.

Cong‐Ying Zhou, D. Romo, Satyamaheshwar Peddibhotla, 2010, Organic Letters.

Discovery of Small Molecule Activators of Chemokine Receptor CXCR4 That Improve Diabetic Wound Healing

Liping Zhang, Junyi Hu, S. Malany, 2022, International Journal of Molecular Sciences.

Discovery of a Plasmodium falciparum glucose-6-phosphate dehydrogenase 6-phosphogluconolactonase inhibitor (R,Z)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-(2-fluorobenzylidene)-3-oxo-3,4-dihydro-2H-benzo[b][1,4]thiazine-6-carboxamide (ML276) that reduces parasite growth in vitro.

Stefan Vasile, Eigo Suyama, Michael Vicchiarelli, 2012, Journal of medicinal chemistry.

Stereoselective synthesis of highly substituted Delta1-pyrrolines: exo-selective 1,3-dipolar cycloaddition reactions with azlactones.

J. Tepe, Satyamaheshwar Peddibhotla, 2004, Journal of the American Chemical Society.

Discovery of Anthranilic Acid Derivatives as Difluoromethylornithine Adjunct Agents That Inhibit Far Upstream Element Binding Protein 1 (FUBP1) Function.

J. Arnoletti, David Levens, R. Jha, 2022, Journal of medicinal chemistry.

ML314: A Biased Neurotensin Receptor Ligand for Methamphetamine Abuse.

R. Rodriguiz, W. Wetsel, M. Caron, 2016, ACS chemical biology.

Discovery of ML314, a Brain Penetrant Non-Peptidic β-Arrestin Biased Agonist of the Neurotensin NTR1 Receptor.

M. Caron, T. Chung, M. Hedrick, 2013, ACS medicinal chemistry letters.

Efficient two-step synthesis of methylphytylbenzoquinones: precursor intermediates in the biosynthesis of vitamin E

D. DellaPenna, J. Tepe, Satyamaheshwar Peddibhotla, 2003 .

Efficient Two‐Step Synthesis of Methylphytylbenzoquinones: Precursor Intermediates in the Biosynthesis of Vitamin E.

D. DellaPenna, J. Tepe, Satyamaheshwar Peddibhotla, 2003 .

Cardioprotective inhibitors of reperfusion injury

T. Chung, Derek A. Stonich, R. Kitsis, 2013 .

Repurposing antimalarial aminoquinolines and related compounds for treatment of retinal neovascularization

M. Boulton, S. Vasile, M. Grant, 2018, PloS one.

Chemical biology strategy reveals pathway-selective inhibitor of NF-kappaB activation induced by protein kinase C.

T. Kipps, John Calvin Reed, J. Cashman, 2010, ACS chemical biology.

MondoA coordinately regulates skeletal myocyte lipid homeostasis and insulin signaling.

Rick B. Vega, Xianlin Han, G. Roth, 2016, The Journal of clinical investigation.

Small Molecules Can Selectively Inhibit Ephrin Binding to the EphA4 and EphA2 Receptors*

G. Roth, N. Cosford, R. Noberini, 2008, Journal of Biological Chemistry.

An Optimized Dihydrodibenzothiazepine Lead Compound (SBI-0797750) as a Potent and Selective Inhibitor of Plasmodium falciparum and P. vivax Glucose 6-Phosphate Dehydrogenase 6-Phosphogluconolactonase

S. Rahlfs, T. Chung, M. Hedrick, 2022, Antimicrobial agents and chemotherapy.

Discovery of b-Arrestin Biased, Orally Bioavailable and CNS Penetrant Neurotensin Receptor 1 (NTR1) Allosteric Modulators.

M. Jackson, M. Caron, T. Chung, 2019, Journal of medicinal chemistry.

Discovery of small molecule guanylyl cyclase A receptor positive allosteric modulators

S. Vasile, J. Burnett, S. Malany, 2021, Proceedings of the National Academy of Sciences.

Probing the CXCR6/CXCL16 Axis: Targeting Prevention of Prostate Cancer Metastasis

R. Taichman, T. Chung, M. Hedrick, 2014 .

Discovery of small molecule antagonists of chemokine receptor CXCR6 that arrest tumor growth in SK-HEP-1 mouse xenografts as a model of hepatocellular carcinoma.

A. Pinkerton, D. Divlianska, E. Sugarman, 2019, Bioorganic & medicinal chemistry letters.

Discovery of ML358, a Selective Small Molecule Inhibitor of the SKN-1 Pathway Involved in Drug Detoxification and Resistance in Nematodes.

C. Leung, K. Choe, A. Pinkerton, 2015, ACS chemical biology.

Triazolothiadiazine derivative positively modulates CXCR4 signaling and improves diabetic wound healing

Liping Zhang, Junyi Hu, Qi-Yin Chen, 2023, Biochemical pharmacology.

MondoA coordinately regulates skeletal myocyte lipid homeostasis and insulin signaling.

Rick B. Vega, Xianlin Han, G. Roth, 2016, The Journal of clinical investigation.

Stereoselective synthesis of highly substituted Delta1-pyrrolines: exo-selective 1,3-dipolar cycloaddition reactions with azlactones.

J. Tepe, Satyamaheshwar Peddibhotla, 2004, Journal of the American Chemical Society.