Chenghong Zhang

发表

Cross-Species Comparison of the Metabolism and Excretion of Zoniporide: Contribution of Aldehyde Oxidase to Interspecies Differences

R. Obach, T. Smolarek, D. Dalvie, 2010, Drug Metabolism and Disposition.

Elucidating the structure and cytochrome P450-mediated mechanism for novel metabolites of GDC-0575 in rats

Yuan Chen, C. Han, J. Napolitano, 2022, Xenobiotica; the fate of foreign compounds in biological systems.

Novel mechanism for dehalogenation and glutathione conjugation of dihalogenated anilines in human liver microsomes: evidence for ipso glutathione addition.

Kevin A Ford, J. Driscoll, C. Hop, 2011, Chemical research in toxicology.

Thioredoxin-1 Is a Target to Attenuate Alzheimer-Like Pathology in Diabetic Encephalopathy by Alleviating Endoplasmic Reticulum Stress and Oxidative Stress

Xiang Ren, Jingyun Liu, Chenghong Zhang, 2021, Frontiers in Physiology.

Metabolism, Pharmacokinetics, and Excretion of a Cholesteryl Ester Transfer Protein Inhibitor, Torcetrapib, in Rats, Monkeys, and Mice: Characterization of Unusual and Novel Metabolites by High-Resolution Liquid Chromatography-Tandem Mass Spectrometry and 1H Nuclear Magnetic Resonance

C. Prakash, D. Dalvie, M. Potchoiba, 2008, Drug Metabolism and Disposition.

An Active Learning Approach for Identifying Adverse Drug Reaction-Related Text from Social Media Using Various Document Representations

Jing Liu, Lihua Huang, Chenghong Zhang, 2021, WISA.

Pharmacokinetics, Metabolism, and Excretion of Torcetrapib, a Cholesteryl Ester Transfer Protein Inhibitor, in Humans

R. Obach, T. Smolarek, A. Vaz, 2008, Drug Metabolism and Disposition.

Metabolism and Excretion of Torcetrapib , a CETP Inhibitor , in Humans

R. Obach, T. Smolarek, A. Vaz, 2008 .

A Novel Depurination Methodology to Assess DNA Alkylation of Chloro-Bis-Seco-Cyclopropylbenzoindoles Allowed for Comparison of Minor-Groove Reactivity

BinQing Wei, P. Dragovich, C. Khojasteh, 2019, Drug Metabolism and Disposition.

Metabolism, Pharmacokinetics and Excretion of a Cholesteryl Ester Transfer Protein Inhibitor, Torcetrapib, in Rats, Monkeys, and Mice: Characterization of Unusual and Novel Metabolites by High Resolution LC-MS/MS

C. Prakash, D. Dalvie, M. Potchoiba, 2008 .

Quantification of 2'-fluoro-2'-deoxyuridine and 2'-fluoro-2'-deoxycytidine in DNA and RNA isolated from rats and woodchucks using LC/MS/MS.

J. Swenberg, Chenghong Zhang, R. Bendele, 2002, Chemical research in toxicology.

Discovery of novel PI3-kinase δ specific inhibitors for the treatment of rheumatoid arthritis: taming CYP3A4 time-dependent inhibition.

P. Savy, Steve Price, A. Nadin, 2012, Journal of medicinal chemistry.

THE IMPACT OF P-GLYCOPROTEIN ON THE DISPOSITION OF DRUGS TARGETED FOR INDICATIONS OF THE CENTRAL NERVOUS SYSTEM: EVALUATION USING THE MDR1A/1B KNOCKOUT MOUSE MODEL

Xi Chen, Karthik Venkatakrishnan, Matthew Troutman, 2005, Drug Metabolism and Disposition.

Bioactivation of α,β-Unsaturated Carboxylic Acids Through Acyl Glucuronidation

J. Grandner, Kevin Johnson, E. Choo, 2020, Drug Metabolism and Disposition.

For a series of methylindole analogs, reactive metabolite formation is a poor predictor of intrinsic cytotoxicity in human hepatocytes

C. Hop, D. Misner, J. Halladay, 2014 .

Strategies to Mitigate the Bioactivation of Aryl Amines.

Matthew L Landry, Huifen Chen, Shuguang Ma, 2020, Chemical research in toxicology.

Comparative assessment for rat strain differences in metabolic profiles of 14 drugs in Wistar Han and Sprague Dawley hepatocytes

Zhengyin Yan, Susan D. Wong, Donglu Zhang, 2020, Xenobiotica; the fate of foreign compounds in biological systems.

Drug–Drug Interaction Potential of Marketed Oncology Drugs: In Vitro Assessment of Time-Dependent Cytochrome P450 Inhibition, Reactive Metabolite Formation and Drug–Drug Interaction Prediction

A. Galetin, S. Mukadam, Suzanne Tay, 2012, Pharmaceutical Research.

Drug–Drug Interaction Potential of Marketed Oncology Drugs: In Vitro Assessment of Time-Dependent Cytochrome P450 Inhibition, Reactive Metabolite Formation and Drug–Drug Interaction Prediction

A. Galetin, S. Mukadam, Suzanne Tay, 2012, Pharmaceutical Research.

An Integrated Strategy for Assessing the Metabolic Stability and Biotransformation of Macrocyclic Peptides in Drug Discovery toward Oral Delivery.

Shaofei Ji, E. Plise, Uchenna A. Anene, 2022, Analytical chemistry.

Immolation of p-Aminobenzyl Ether Linker and Payload Potency and Stability Determine the Cell-Killing Activity of Antibody-Drug Conjugates with Phenol-Containing Payloads.

B. Vollmar, BinQing Wei, P. Dragovich, 2018, Bioconjugate chemistry.

Identification of a Discrete Diglucuronide of GDC-0810 in Human Plasma after Oral Administration.

E. Choo, J. Kenny, Lichuan Liu, 2023, Drug Metabolism And Disposition.

1 Identification of a Discrete Diglucuronide of GDC-0810 in Human Plasma after Oral Administration

E. Choo, J. Kenny, Lichuan Liu, 2023 .

C. Prakash, D. Dalvie, M. Potchoiba, 2008, Drug Metabolism and Disposition.

Reactive metabolite screen for reducing candidate attrition in drug discovery.

H. Fouda, M. J. Avery, Chenghong Zhang, 2001, Advances in experimental medicine and biology.