Hongrui Tao

发表

iASPP–PP1 complex is required for cytokinetic abscission by controlling CEP55 dephosphorylation

H. Saiyin, Shimin Zhao, Yao Li, 2018, Cell Death & Disease.

Identification of 5-benzylidene-2-phenylthiazolones as potent PRMT5 inhibitors by virtual screening, structural optimization and biological evaluations.

Cheng Luo, Zhifeng Chen, Kongkai Zhu, 2018, Bioorganic chemistry.

Discovery of 2-substituted-N-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamide as potent and selective protein arginine methyltransferases 5 inhibitors: Design, synthesis and biological evaluation.

Kaixian Chen, Hualiang Jiang, Jingwei Shao, 2019, European journal of medicinal chemistry.

Discovery of alkoxy benzamide derivatives as novel BPTF bromodomain inhibitors via structure-based virtual screening.

Kaixian Chen, Hualiang Jiang, C. Luo, 2019, Bioorganic chemistry.

A potent PGK1 antagonist reveals PGK1 regulates the production of IL-1β and IL-6

Kaixian Chen, Hualiang Jiang, C. Luo, 2022, Acta pharmaceutica Sinica. B.

Discovery of New Selective Butyrylcholinesterase (BChE) Inhibitors with Anti-Aβ Aggregation Activity: Structure-Based Virtual Screening, Hit Optimization and Biological Evaluation

Hua Zhang, K. Zhu, Cheng-Shi Jiang, 2019, Molecules.

L-5-hydroxytryptophan promotes antitumor immunity by inhibiting PD-L1 inducible expression

Kaixian Chen, Hualiang Jiang, C. Luo, 2022, Journal for ImmunoTherapy of Cancer.

Discovery of new potent protein arginine methyltransferase 5 (PRMT5) inhibitors by assembly of key pharmacophores from known inhibitors.

Hua Zhang, K. Zhu, Cheng-Shi Jiang, 2018, Bioorganic & medicinal chemistry letters.

Synthesis and biological evaluation of 2-(3-aminophenyl)-benzothiazoles as antiproliferative and apoptosis-inducing agents

Hua Zhang, K. Zhu, L. A. Muehlmann, 2018, Monatshefte für Chemie - Chemical Monthly.

Discovery of New α-Glucosidase Inhibitors: Structure-Based Virtual Screening and Biological Evaluation

K. Zhu, C. Yuan, Cheng-Shi Jiang, 2021, Frontiers in Chemistry.

11-Methoxytabersonine Induces Necroptosis with Autophagy through AMPK/mTOR and JNK Pathways in Human Lung Cancer Cells.

Yan Xu, Hua Zhang, Mei Yu, 2020, Chemical & pharmaceutical bulletin.

Asperbutenolide A, an unusual aromatic butenolide dimer with diverse bioactivities from a marine-derived fungus Aspergillus terreus SCAU011

Jie Bao, Hua Zhang, K. Zhu, 2020 .

Inhibition of autophagy by a small molecule through covalent modification of LC3.

Kaixian Chen, Hualiang Jiang, Junyan Lu, 2021, Angewandte Chemie.

Identification and assessments of novel and potent small-molecule inhibitors of EED-EZH2 interaction of polycomb repressive complex 2 by computational methods and biological evaluations.

Hua Zhang, K. Zhu, Hongrui Tao, 2019, Chemical & pharmaceutical bulletin.

Discovery and biological evaluation of vinylsulfonamide derivatives as highly potent, covalent TEAD autopalmitoylation inhibitors.

Kaixian Chen, Hualiang Jiang, C. Luo, 2019, European journal of medicinal chemistry.

Discovery of novel BET inhibitors by drug repurposing of nitroxoline and its analogues.

Hao Jiang, Cheng Luo, Zhifeng Chen, 2017, Organic & biomolecular chemistry.

Discovery of trisubstituted nicotinonitrile derivatives as novel human GCN5 inhibitors through AlphaScreen-based high throughput screening

Kaixian Chen, Hualiang Jiang, C. Luo, 2019, RSC advances.

Covalent Inhibitors Allosterically Block the Activation of Rho Family Proteins and Suppress Cancer Cell Invasion

Kaixian Chen, Hualiang Jiang, C. Luo, 2020, Advanced science.

Rational Design, synthesis and biological evaluation of novel triazole derivatives as potent and selective PRMT5 inhibitors with antitumor activity

Cheng Luo, Hua Zhang, Kongkai Zhu, 2019, Journal of Computer-Aided Molecular Design.

Identification of a novel selective small-molecule inhibitor of protein arginine methyltransferase 5 (PRMT5) by virtual screening, resynthesis and biological evaluations.

Cheng Luo, Kongkai Zhu, Hongrui Tao, 2018, Bioorganic & medicinal chemistry letters.

Interaction assessments of the first S-adenosylmethionine competitive inhibitor and the essential interacting partner methylosome protein 50 with protein arginine methyltransferase 5 by combined computational methods.

C. Luo, Hua Zhang, K. Zhu, 2018, Biochemical and biophysical research communications.

Discovery of Novel PRMT5 Inhibitors by Virtual Screening and Biological Evaluations.

Hua Zhang, K. Zhu, Hongrui Tao, 2019, Chemical & pharmaceutical bulletin.

Spermine is a natural suppressor of AR signaling in castration-resistant prostate cancer.

Hualiang Jiang, Fei Li, Yuanyuan Zhang, 2023, Cell reports.