Daniel G. Fraser

发表

LPS-induced premature osteocyte senescence: Implications in inflammatory alveolar bone loss and periodontal disease pathogenesis.

S. Khosla, J. Farr, D. Monroe, 2020, Bone.

Accelerated osteocyte senescence and skeletal fragility in mice with type 2 diabetes.

Katherine L. O'Grady, A. Thoreson, S. Khosla, 2020, JCI insight.

Circulating osteoblast-lineage cells in humans.

B. Riggs, S. Khosla, J. Lamsam, 2005, The New England journal of medicine.

TIEG1 Null Mouse-Derived Osteoblasts Are Defective in Mineralization and in Support of Osteoclast Differentiation In Vitro

J. V. van Deursen, M. Oursler, R. Turner, 2005, Molecular and Cellular Biology.

Skeletal Consequences of Deletion of Steroid Receptor Coactivator-2/Transcription Intermediary Factor-2*

P. Chambon, S. Khosla, B. O’Malley, 2009, The Journal of Biological Chemistry.

Senolytics Improve Physical Function and Increase Lifespan in Old Age

D. Allison, N. LeBrasseur, S. Khosla, 2018, Nature Medicine.

Senescent cells exacerbate chronic inflammation and contribute to periodontal disease progression in old mice.

S. Khosla, J. Farr, D. Monroe, 2020, Journal of periodontology.

Dose-response of estrogen on bone versus the uterus in ovariectomized mice.

B. Riggs, S. Khosla, E. Atkinson, 2004, European journal of endocrinology.

Effects of chronic estrogen treatment on modulating age‐related bone loss in female mice

S. Khosla, M. Oursler, M. Roforth, 2010, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Independent Roles of Estrogen Deficiency and Cellular Senescence in the Pathogenesis of Osteoporosis: Evidence in Young Adult Mice and Older Humans

S. Khosla, J. Farr, J. Kirkland, 2019, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Deletion of Estrogen Receptor Beta in Osteoprogenitor Cells Increases Trabecular but Not Cortical Bone Mass in Female Mice

S. Khosla, M. McGee-Lawrence, J. Westendorf, 2016, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Targeting cellular senescence prevents age-related bone loss in mice

N. LeBrasseur, S. Khosla, J. Farr, 2017, Nature Medicine.

Identification of Senescent Cells in the Bone Microenvironment

N. LeBrasseur, L. Bonewald, S. Khosla, 2016, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Skeletal Effects of Estrogen Are Mediated by Opposing Actions of Classical and Nonclassical Estrogen Receptor Pathways

P. Chambon, S. Khosla, A. Krust, 2005, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

TGFbeta inducible early gene-1 knockout mice display defects in bone strength and microarchitecture.

K. An, P. Amadio, S. Bensamoun, 2006, Bone.

miR‐219a‐5p Regulates Rorβ During Osteoblast Differentiation and in Age‐related Bone Loss

S. Khosla, J. Farr, A. V. van Wijnen, 2018, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Ability of Circulating Human Hematopoietic Lineage Negative Cells to Support Hematopoiesis

S. Khosla, R. Jilka, P. Peris, 2015, Journal of cellular biochemistry.

Osteoprotection Through the Deletion of the Transcription Factor Rorβ in Mice

D. Forrest, S. Khosla, J. Farr, 2018, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Distinct effects of loss of classical estrogen receptor signaling versus complete deletion of estrogen receptor alpha on bone.

S. Khosla, D. Monroe, Daniel G. Fraser, 2011, Bone.

Effects of loss of classical estrogen response element signaling on bone in male mice.

P. Chambon, S. Khosla, A. Krust, 2007, Endocrinology.

Examination of ERα signaling pathways in bone of mutant mouse models reveals the importance of ERE-dependent signaling.

S. Khosla, M. Roforth, D. Monroe, 2012, Endocrinology.

Corrigendum: Targeting cellular senescence prevents age-related bone loss in mice

N. LeBrasseur, S. Khosla, J. Farr, 2017, Nature Medicine.

Induction of fracture repair by mesenchymal cells derived from human embryonic stem cells or bone marrow

D. Kaufman, Anita H. Undale, T. Hefferan, 2011, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Identification of Senescent Cells in the Bone Microenvironment

N. LeBrasseur, L. Bonewald, S. Khosla, 2016, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.