B. Baragaña

发表

Protease-catalyzed peptide synthesis on solid support.

P. Halling, R. Ulijn, S. Flitsch, 2002, Journal of the American Chemical Society.

Challenges and recent progress in drug discovery for tropical diseases

I. Gilbert, M. D. Rycker, S. Duce, 2018, Nature.

Challenges and recent progress in drug discovery for tropical diseases

I. Gilbert, S. Duce, M. De Rycker, 2018, Nature.

A novel multiple-stage antimalarial agent that inhibits protein synthesis

David W. Gray, E. Winzeler, S. Meister, 2015, Nature.

Differentially-protected steroidal triamines; scaffolds with potential for medicinal, supramolecular, and combinatorial chemistry.

Vicente del Amo, A. P. Davis, L. Siracusa, 2004, Organic & biomolecular chemistry.

Lysyl-tRNA synthetase, a target for urgently needed M. tuberculosis drugs

Robert H Bates, L. Stojanovski, K. Read, 2022, Nature Communications.

Toolkit of Approaches To Support Target-Focused Drug Discovery for Plasmodium falciparum Lysyl tRNA Synthetase

I. Gilbert, D. Robinson, L. S. Torrie, 2022, ACS infectious diseases.

CRISPR-based oligo recombineering prioritizes apicomplexan cysteines for drug discovery

J. Baum, S. Wyllie, E. Weerapana, 2022, Nature Microbiology.

Selective delivery of 2-hydroxy APA to Trypanosoma brucei using the melamine motif

Farah El Mazouni, I. Gilbert, M. Barrett, 2010, Bioorganic & medicinal chemistry letters.

High-Throughput Screening Platform To Identify Inhibitors of Protein Synthesis with Potential for the Treatment of Malaria

Fernando Sánchez-Román Terán, I. Gilbert, J. Baum, 2022, Antimicrobial agents and chemotherapy.

Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis

Juan A. Bueren-Calabuig, Andrei V. Pisliakov, David W. Gray, 2019, Proceedings of the National Academy of Sciences.

Biochemical and Structural Characterization of Selective Allosteric Inhibitors of the Plasmodium falciparum Drug Target, Prolyl-tRNA-synthetase

David W. Gray, K. Read, I. Gilbert, 2016, ACS infectious diseases.

High Diastereoselective Synthesis of Threo or Erythro Aminoalkyl Epoxides from .alpha.-Amino Acids

J. Barluenga, J. Concellón, B. Baragaña, 1995 .

Discovery of a Quinoline-4-carboxamide Derivative with a Novel Mechanism of Action, Multistage Antimalarial Activity, and Potent in Vivo Efficacy

David W. Gray, E. Winzeler, S. Meister, 2016, Journal of medicinal chemistry.

Trisubstituted Pyrimidines as Efficacious and Fast-Acting Antimalarials

E. Winzeler, S. Meister, S. Norval, 2016, Journal of medicinal chemistry.

The first direct preparation of chiral functionalised ketones and their synthetic uses

J. Barluenga, J. Concellón, B. Baragaña, 1994 .

Enantioselective transport by a steroidal guanidinium receptor.

P. Prados, A. P. Davis, J. D. de Vries, 2002, Chemistry.

Chemogenomics identifies acetyl-coenzyme A synthetase as a target for malaria treatment and prevention

E. Winzeler, I. Gilbert, M. Llinás, 2021, Cell chemical biology.

β-Branched acyclic nucleoside analogues as inhibitors of Plasmodium falciparum dUTPase.

Ian H. Gilbert, Keith S. Wilson, Marcel Kaiser, 2011, Bioorganic & medicinal chemistry.

MalDA, Accelerating Malaria Drug Discovery

E. Winzeler, I. Gilbert, K. Chibale, 2021, Trends in parasitology.

Design, Synthesis, and Evaluation of 5′‐Diphenyl Nucleoside Analogues as Inhibitors of the Plasmodium falciparum dUTPase

I. Gilbert, K. Wilson, J. Brannigan, 2011, ChemMedChem.

Prioritization of Molecular Targets for Antimalarial Drug Discovery

E. Winzeler, I. Gilbert, M. Siegel, 2021, ACS infectious diseases.

Validation of Plasmodium falciparum dUTPase as the target of 5′-tritylated deoxyuridine analogues with anti-malarial activity

I. Gilbert, S. Müller, D. González-Pacanowska, 2019, Malaria Journal.

SYNTHETIC APPLICATIONS OF 1-AMINOALKYL CHLOROMETHYL KETONES. SYNTHESIS OF ENANTIOPURE 3-AZETIDINOLS AND AMINOALKYL EPOXIDES

J. Barluenga, J. Concellón, B. Baragaña, 1997 .

Mycobacterium tuberculosis Phe-tRNA synthetase: structural insights into tRNA recognition and aminoacylation

I. Gilbert, A. Joachimiak, J. Wower, 2021, Nucleic acids research.

Corrigendum: A novel multiple-stage antimalarial agent that inhibits protein synthesis

E. Winzeler, S. Meister, J. Rayner, 2016, Nature.

Diastereoselective reduction of (S)-1-chloro-3-silyloxybutan-2-one. Synthesis of enantiopure (2S,3R) and (2S,3S) O-tert-butyldimethylsilyl-3,4-epoxybutan-2-ol

R. Álvarez, J. Concellón, B. Baragaña, 1999 .

Perspective on Schistosomiasis Drug Discovery: Highlights from a Schistosomiasis Drug Discovery Workshop at Wellcome Collection, London, September 2022

K. Read, I. Gilbert, N. Lo, 2023, ACS infectious diseases.

Validation of Plasmodium falciparum dUTPase as the target of 5′-tritylated deoxyuridine analogues with anti-malarial activity

I. Gilbert, S. Müller, D. González-Pacanowska, 2019, Malaria Journal.

Screening a protein kinase inhibitor library against Plasmodium falciparum

I. Gilbert, A. Fairlamb, P. Wyatt, 2017, Malaria Journal.

Mode of action studies confirm on-target engagement of lysyl-tRNA synthetase inhibitor and lead to new selection marker for Cryptosporidium

S. Wyllie, Simona Seizova, B. Baragaña, 2023, Frontiers in Cellular and Infection Microbiology.