K. Endo

发表

Epoetin beta pegol alleviates oxidative stress and exacerbation of renal damage from iron deposition, thereby delaying CKD progression in progressive glomerulonephritis rats

Ken Aizawa, Y. Shimonaka, M. Hirata, 2015, Physiological reports.

Epoetin beta pegol prevents endothelial dysfunction as evaluated by flow-mediated dilation in chronic kidney disease rats.

K. Serizawa, Ken Aizawa, M. Hirata, 2015, European journal of pharmacology.

Combination therapy with eldecalcitol and alendronate has therapeutic advantages over monotherapy by improving bone strength.

A. Shiraishi, S. Takeda, M. Mihara, 2012, Bone.

Epoetin beta pegol ameliorates flow‐mediated dilation with improving endothelial nitric oxide synthase coupling state in nonobese diabetic rats

K. Serizawa, Y. Shimonaka, M. Hirata, 2017, Cardiovascular therapeutics.

22-Oxacalcitriol prevents progression of endothelial dysfunction through antioxidative effects in rats with type 2 diabetes and early-stage nephropathy.

M. Fukagawa, K. Serizawa, Ken Aizawa, 2013, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Oncogenic Collaboration of the Cyclin D1 (PRAD1, bcl‐1) Gene with a Mutated p53 and an Activated ras Oncogene in Neoplastic Transformation

A. Arnold, T. Motokura, K. Uchimaru, 1996, Japanese journal of cancer research : Gann.

Neoplastic Transformation of Normal Rat Embryo Fibroblasts by a Mutated p53 and an Activated ras Oncogene Induces Parathyroid Hormone-related Peptide Gene Expression and Causes Hypercalcemia in Nude Mice(*)

T. Motokura, E. Ogata, K. Ikeda, 1995, The Journal of Biological Chemistry.

Combination treatment with eldecalcitol (ED-71) and raloxifene improves bone mechanical strength by suppressing bone turnover and increasing bone mineral density in ovariectomized rats.

A. Shiraishi, S. Takeda, M. Mihara, 2013, Bone.

Intermittent Ibandronate Maintains Bone Mass, Bone Structure, and Biomechanical Strength of Trabecular and Cortical Bone After Discontinuation of Parathyroid Hormone Treatment in Ovariectomized Rats

H. Tomizawa, Y. Matsumoto, K. Serizawa, 2017, Calcified Tissue International.

Histological Effects of the Combined Administration of Eldecalcitol and a Parathyroid Hormone in the Metaphyseal Trabeculae of Ovariectomized Rats

Kimimitsu Oda, N. Amizuka, Minqi Li, 2018, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Sequential Treatment with Eldecalcitol After PTH Improves Bone Mechanical Properties of Lumbar Spine and Femur in Aged Ovariectomized Rats

N. Amizuka, S. Takeda, T. Hasegawa, 2018, Calcified Tissue International.

Treatment with the combination of ibandronate plus eldecalcitol has a synergistic effect on inhibition of bone resorption without suppressing bone formation in ovariectomized rats.

F. Bauss, S. Takeda, M. Sugimoto, 2015, Bone.

Long-Term Treatment with Eldecalcitol (1α, 25-Dihydroxy-2β- (3-hydroxypropyloxy) Vitamin D3) Suppresses Bone Turnover and Leads to Prevention of Bone Loss and Bone Fragility in Ovariectomized Rats

Susan Y. Smith, R. Samadfam, S. Takeda, 2014, Calcified Tissue International.

1,25‐Dihydroxyvitamin D3 as Well as Its Analogue OCT Lower Blood Calcium Through Inhibition of Bone Resorption in Hypercalcemic Rats with Continuous Parathyroid Hormone–Related Peptide Infusion

Toshitaka Nakamura, K. Ikeda, E. Ogata, 2000, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Monthly oral ibandronate 100 mg is as effective as monthly intravenous ibandronate 1 mg in patients with various pathologies in the MOVEST study

Toshitaka Nakamura, H. Hagino, Masako Ito, 2018, Journal of Bone and Mineral Metabolism.

Epoetin beta pegol, but not recombinant erythropoietin, retains its hematopoietic effect in vivo in the presence of the sialic acid-metabolizing enzyme sialidase

Y. Shimonaka, M. Hirata, R. Kawasaki, 2016, International Journal of Hematology.

In subtotally nephrectomized rats 22-oxacalcitriol suppresses parathyroid hormone with less risk of cardiovascular calcification or deterioration of residual renal function than 1,25(OH)2 vitamin D3.

M. Fukagawa, N. Fukushima, H. Ohkawa, 2003, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Eldecalcitol prevents endothelial dysfunction in postmenopausal osteoporosis model rats.

K. Serizawa, S. Takeda, R. Kawasaki, 2016, The Journal of endocrinology.

Active vitamin D3 administration improves locomotive ability of mice with rotarod training

M. Mihara, K. Endo, Sadaoki Sakai, 2012 .

A new active vitamin D analog, ED‐71, causes increase in bone mass with preferential effects on bone in osteoporotic patients

N. Kubodera, Y. Uchiyama, K. Endo, 2003, Journal of cellular biochemistry.

Eldecalcitol, an Active Vitamin D3 Derivative, Prevents Trabecular Bone Loss and Bone Fragility in Type I Diabetic Model Rats

M. Saito, K. Marumo, S. Takeda, 2017, Calcified Tissue International.

Nicorandil suppresses urinary protein excretion and activates eNOS in Dahl salt-sensitive hypertensive rats

K. Serizawa, K. Endo, K. Yogo, 2015, Clinical and Experimental Nephrology.

Renoprotection by Continuous Erythropoietin Receptor Activator in Puromycin Aminonucleoside-Induced Nephrotic Syndrome

S. Takeda, H. Kanada, Y. Moriguchi, 2012, American Journal of Nephrology.

Sequential Treatment with Eldecalcitol After PTH Improves Bone Mechanical Properties of Lumbar Spine and Femur in Aged Ovariectomized Rats

N. Amizuka, S. Takeda, T. Hasegawa, 2018, Calcified Tissue International.

Evidence for the uptake of a vitamin D analogue (OCT) by a human carcinoma and its effect of suppressing the transcription of parathyroid hormone-related peptide gene in vivo.

E. Ogata, K. Ikeda, K. Kumaki, 1994, The Journal of biological chemistry.

Vitamin D Receptor Signaling Enhances Locomotive Ability in Mice

Miho Suzuki, S. Takeda, M. Hirata, 2015, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Long-Term Treatment with Eldecalcitol (1α, 25-Dihydroxy-2β- (3-hydroxypropyloxy) Vitamin D3) Suppresses Bone Turnover and Leads to Prevention of Bone Loss and Bone Fragility in Ovariectomized Rats

Susan Y. Smith, R. Samadfam, S. Takeda, 2014, Calcified Tissue International.

Effect of Combination Treatment with a Vitamin D Analog (OCT) and a Bisphosphonate (AHPrBP) in a Nude Mouse Model of Cancer‐Associated Hypercalcemia

T. Fujita, T. Teramoto, E. Ogata, 1998, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Attenuated up‐regulation of vitamin D‐dependent calcium‐binding proteins by 22‐oxa‐1,25‐dihydroxyvitamin D3 in uremic rats: A possible mechanism for less‐calcemic action

K. Kurokawa, M. Fukagawa, N. Kubodera, 1998 .

A comparison between daily and thrice-weekly i.v. administration of 1,25-dihydroxy-22-oxavitamin D(3) regarding suppression of parathyroid hormone secretion and calcaemic action in uraemic rats.

E. Slatopolsky, K. Kurokawa, M. Fukagawa, 2002, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Renoprotective effect of epoetin beta pegol by the prevention of M2 macrophage recruitment in Thy-1 rats

S. Takeda, M. Hirata, R. Kawasaki, 2014, Journal of Nephrology.

Nicorandil prevents sirolimus-induced production of reactive oxygen species, endothelial dysfunction, and thrombus formation.

K. Hirano, K. Serizawa, H. Ishida, 2015, Journal of pharmacological sciences.

[A comparison between 1,25-dihydroxy-22-oxavitamin D3 and 1,25-dihydroxyvitamin D3 regarding suppression of parathyroid hormone secretion and calcemic action].

M. Fukagawa, K. Endo, 2002, Clinical calcium.

Synthesis of 1a,25-dihydroxy-22-thiavitamin D 3 and related analogs

N. Kubodera, A. Kawase, M. Hirata, 1995 .

Synthetic Studies of Vitamin D Analogues. Part 21. Synthesis of 1. alpha.,25-Dihydroxy-22-thiavitamin D3 and Related Analogues.

N. Kubodera, A. Kawase, M. Hirata, 1995 .

A comparison between 1,25-dihydroxy-22-oxavitamin D(3) and 1,25-dihydroxyvitamin D(3) regarding suppression of parathyroid hormone secretion and calcaemic action.

M. Fukagawa, N. Kubodera, F. Ichikawa, 2002, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Binding of vitamin D to low-density-lipoprotein (LDL) and LDL receptor-mediated pathway into cells.

E. Ogata, T. Teramoto, N. Kubodera, 1995, Biochemical and biophysical research communications.