A. Gear

发表

P-Selectin–Mediated Platelet-Neutrophil Aggregate Formation Activates Neutrophils in Mouse and Human Sickle Cell Disease*

R. Polanowska-Grabowska, J. Linden, J. Field, 2010, Arteriosclerosis, thrombosis, and vascular biology.

Platelet adhesion to collagen via the alpha 2 beta 1 integrin under arterial flow conditions causes rapid tyrosine phosphorylation of pp125FAK.

R. Polanowska-Grabowska, M. Geanacopoulos, A. Gear, 1993, The Biochemical journal.

Platelet Adhesion to Collagen and Collagen-Related Peptide Under Flow: Roles of the &agr;2&bgr;1 Integrin, GPVI, and Src Tyrosine Kinases

R. Polanowska-Grabowska, J. Gibbins, A. Gear, 2003, Arteriosclerosis, thrombosis, and vascular biology.

Platelet adhesion to collagen under flow causes dissociation of a phosphoprotein complex of heat-shock proteins and protein phosphatase 1.

J. Shabanowitz, D. Hunt, R. Polanowska-Grabowska, 1997, Blood.

Platelet Calcium and Quenched‐Flow Aggregation Kinetics in Essential Hypertension

M. Taylor, C. Ayers, A. Gear, 1989, Hypertension.

Thrombin causes subsecond changes in protein phosphorylation of platelets

F. Spielberg, A. Gear, D. J. Carty, 1986 .

shape change by nitric oxide Protein kinase A mediates inhibition of the thrombin-induced platelet

S. Døskeland, F. Selheim, H. Holmsen, 2013 .

Protein kinase A mediates inhibition of the thrombin-induced platelet shape change by nitric oxide.

S. Døskeland, F. Selheim, H. Holmsen, 2004, Blood.

Atrial natriuretic factor in essential hypertension.

C. Ayers, M. Taylor, A. Gear, 1989, Life sciences.

Shiga Toxin 2 and Lipopolysaccharide Induce Human Microvascular Endothelial Cells To Release Chemokines and Factors That Stimulate Platelet Function

R. Polanowska-Grabowska, T. Obrig, A. Gear, 2005, Infection and Immunity.

Human platelet aggregation is not altered by Shiga toxins 1 or 2.

R. Polanowska-Grabowska, T. Obrig, A. Gear, 2000, Thrombosis research.

Shiga toxin 2 and lipopolysaccharide cause monocytic THP-1 cells to release factors which activate platelet function

R. Polanowska-Grabowska, T. Obrig, A. Gear, 2005, Thrombosis and Haemostasis.

Sphingomyelinase activity in human platelets.

S. Chatterjee, A. Gear, C. G. Simon, 1998, Thrombosis research.

The influence of recombinant tissue-type plasminogen activator and plasmin on platelet aggregation: a quenched-flow study

A. Gear, S. Dittmar, 1993 .

chemokines MDC, TARC, and SDF-1 to stimulate platelet function Adenosine diphosphate strongly potentiates the ability of the

S. Raha, D. Camerini, A. Gear, 2013 .

Adenosine diphosphate strongly potentiates the ability of the chemokines MDC, TARC, and SDF-1 to stimulate platelet function.

R. Polanowska-Grabowska, S. Raha, D. Camerini, 2001, Blood.

Membrane-destabilizing properties of C2-ceramide may be responsible for its ability to inhibit platelet aggregation.

A. Gear, C. G. Simon, 1998, Biochemistry.

Radiographic contrast agents and platelet function: a quenched-flow study.

C. Ayers, M. Taylor, D. Angello, 1991, Catheterization and cardiovascular diagnosis.

Exchange of C(16)-ceramide between phospholipid vesicles.

C. Simon, P. W. Holloway, A. Gear, 1999, Biochemistry.

Geldanamycin disrupts platelet-membrane structure, leading to membrane permeabilization and inhibition of platelet aggregation.

R. Polanowska-Grabowska, A. Gear, S. Suttitanamongkol, 2000, The Biochemical journal.

Research : Focus on Platelets P-Selectin – Mediated Platelet-Neutrophil Aggregate Formation Activates Neutrophils in Mouse and Human Sickle Cell Disease *

R. Polanowska-Grabowska, J. Linden, Kori L Wallace, 2010 .

Endothelium-dependent potentiation of human platelet aggregation.

M. Peach, A. Loeb, A. Gear, 1989, Thrombosis research.

Sphingolipid metabolism during human platelet activation.

A. Gear, C. G. Simon, 1999, Thrombosis research.

Platelet adhesion to collagen activates a phosphoprotein complex of heat-shock proteins and protein phosphatase 1

R. Polanowska-Grabowska, A. Gear, C. G. Simon, 2005, Journal of Neural Transmission.

Platelet adhesion assays under flow using matrix protein-coupled adhesion columns.

R. Polanowska-Grabowska, A. Gear, 2004, Methods in molecular biology.

Platelet Adhesion to Collagen Type I, Collagen Type IV, von Willebrand Factor, Fibronectin, Laminin and Fibrinogen: Rapid Kinetics under Shear

R. Polanowska-Grabowska, A. Gear, C. G. Simon, 1999, Thrombosis and Haemostasis.

Activation of protein kinase C is required for the stable attachment of adherent platelets to collagen but is not needed for the initial rapid adhesion under flow conditions.

R. Polanowska-Grabowska, A. Gear, 1999, Arteriosclerosis, thrombosis, and vascular biology.

DIRECT COUNTING AND SIZING OF MITOCHONDRIA IN SOLUTION

J. Bednarek, A. Gear, 1972, The Journal of cell biology.

Rhodamine 6G. A potent inhibitor of mitochondrial oxidative phosphorylation.

A. Gear, 1974, The Journal of biological chemistry.

Local anesthetic effects on TXA2 receptor mediated platelet aggregation using quenched flow aggregometry.

M. Durieux, B. Lo, A. Gear, 1999, Advances in experimental medicine and biology.

The effect of temperature on mitochondrial membrane-linked reactions.

A. Gear, M. P. Lee, 1974, The Journal of biological chemistry.

Control of platelet glycogenolysis; Activation of phosphorylase kinase by calcium.

A. Gear, W. Schneider, 1975, Biochimica et biophysica acta.

Significance of glucose and glycogen metabolism for platelet function.

A. Gear, W. Schneider, A. R. L. Gear, 1975, Ciba Foundation symposium.

Platelet adhesion to collagen under flow conditions in diabetes mellitus.

R. Polanowska-Grabowska, A. Gear, S. Dittmar, 1994, Thrombosis research.

Subsecond calcium dynamics in ADP- and thrombin-stimulated platelets: a continuous-flow approach using indo-1.

A. Gear, G. Jones, 1988, Blood.

Platelets in Thrombotic and Non-thrombotic Disorders: The platelet shape change

R. Polanowska-Grabowska, A. Gear, 2002 .

Platelet adhesion, shape change, and aggregation: rapid initiation and signal transduction events.

A. Gear, 1994, Canadian journal of physiology and pharmacology.

Geldanamycin disrupts platelet-membrane structure, leading to membrane permeabilization and inhibition of platelet aggregation.

R. Polanowska-Grabowska, A. Gear, S. Suttitanamongkol, 2000, The Biochemical journal.

Sub-second oscillations of inositol 1,4,5-trisphosphate and inositol 1,3,4,5-tetrakisphosphate during platelet activation by ADP and thrombin: lack of correlation with calcium kinetics.

S. Raha, A. Gear, G. Jones, 1993, The Biochemical journal.

Platelet Chemokines and Chemokine Receptors: Linking Hemostasis, Inflammation, and Host Defense

D. Camerini, A. Gear, 2003, Microcirculation.

Effects of separate proteolytic and high-affinity binding activities of human thrombin on rapid platelet activation. A quenched-flow study.

A. Gear, D. J. Carty, D. Freas, 1989, The Biochemical journal.

The effect of the hypocholesterolemic drug clofibrate on liver mitochondrial biogenesis. A role for neutral mitochondrial proteases.

A. Albert, J. Bednarek, A. Gear, 1974, The Journal of biological chemistry.

Rapid, respiration-independent binding of alkali metal cations by rat liver mitochondria.

A. Lehninger, A. Gear, 1968, The Journal of biological chemistry.

SOME FEATURES OF MITOCHONDRIA AND FLUFFY LAYER IN REGENERATING RAT LIVER.

A. Gear, 1965, The Biochemical journal.

Heat-shock proteins and platelet function.

R. Polanowska-Grabowska, A. Gear, 2000, Platelets.

Rapid platelet morphological changes visualized by scanning‐electron microscopy: kinetics derived from a quenched‐flow approach

A. Gear, 1984, British journal of haematology.

Targeted Disruption of cd73/Ecto-5′-Nucleotidase Alters Thromboregulation and Augments Vascular Inflammatory Response

K. Ley, Michael L. Smith, A. Zernecke, 2004, Circulation research.

Local Anesthetic Actions on Thromboxane-Induced Platelet Aggregation

M. Hollmann, M. Durieux, B. Lo, 2001, Anesthesia and analgesia.

Reduction in Single Platelets During Primary and Secondary Aggregation

A. Gear, Jon Lambrecht, 1981, Thrombosis and Haemostasis.

Continuous-flow, resistive-particle counting.

A. Gear, 1976, Analytical biochemistry.

Involvement of guanylate cyclase and phosphodiesterases in the functional heterogeneity of human blood platelet subpopulations.

W. Wesemann, E. Schrumpf, A. Gear, 1995, Thrombosis research.

Adhesion efficiency, platelet density and size

R. Polanowska-Grabowska, S. Raha, A. Gear, 1992, British journal of haematology.

Role of cyclic nucleotides in rapid platelet adhesion to collagen.

R. Polanowska-Grabowska, A. Gear, 1994, Blood.

High-speed platelet adhesion under conditions of rapid flow.

R. Polanowska-Grabowska, A. Gear, 1992, Proceedings of the National Academy of Sciences of the United States of America.

LDL oxidized by hypochlorous acid causes irreversible platelet aggregation when combined with low levels of ADP, thrombin, epinephrine, or macrophage-derived chemokine (CCL22).

R. Polanowska-Grabowska, Leon G. Coleman, A. Gear, 2004, Blood.

Potentiation of platelet aggregation by atrial natriuretic peptide.

A. Loeb, A. Gear, 1988, Life sciences.

Targeted Disruption of cd73 /Ecto-5 (cid:1) -Nucleotidase Alters Thromboregulation and Augments Vascular Inflammatory Response Integrative Physiology

K. Ley, Michael L. Smith, A. Zernecke, 2004 .

Respiration-independent displacement of protons from external anionic groups of mitochondria by alkali metal cations.

A. Lehninger, A. Gear, 1967, Biochemical and biophysical research communications.

Calcium signalling and phosphoinositide metabolism in platelets: subsecond events revealed by quenched-flow techniques.

S. Raha, A. Gear, 1993, Advances in experimental medicine and biology.

Rapid blood platelet activation: continuous- and quenched-flow versus stopped-flow approaches.

A. Gear, G. Jones, 1990, The Biochemical journal.

The role of protein kinase C in the initial events of platelet activation by thrombin assessed with a selective inhibitor.

S. Vandenberg, M. Geanacopoulos, A. Gear, 1993, Thrombosis research.

Effect of epinephrine on rapid ADP-induced aggregation, protein phosphorylation, and cytoplasmic calcium dynamics of platelets: a quenched-flow study.

A. Gear, D. J. Carty, D. Freas, 1988, The Journal of laboratory and clinical medicine.

macrophage-derived chemokine ( CCL 22 ) when combined with low levels of ADP , thrombin , epinephrine or LDL oxidized by hypochlorous acid causes irreversible platelet aggregation

R. Polanowska-Grabowska, Leon G. Coleman, A. Gear, 2004 .

Analysis of GTP-binding proteins, phosphoproteins, and cytosolic calcium in functional heterogeneous human blood platelet subpopulations.

K. Hinsch, E. Hinsch, W. Wesemann, 1997, Biochemical pharmacology.

Effect of physiologic shear stresses and calcium on agonist-induced platelet aggregation, secretion, and thromboxane A2 formation.

A. Gear, D. Viisoreanu, 2007, Thrombosis research.

Acid-Base Exchanges in Mitochondria and Suspending Medium during Respiration-linked Accumulation of Bivalent Cations

A. Lehninger, C. Rossi, B. Reynafarje, 1967 .

Heat-shock protein 90 complexes in resting and thrombin-activated platelets.

R. Polanowska-Grabowska, A. Gear, S. Suttitanamongkol, 2002, Biochemical and biophysical research communications.

Application of spray-freezing to the study of rapid platelet reactions by a quenched-flow approach.

M. Geanacopoulos, A. Gear, 1988, Thrombosis research.