D. Lachno

发表

A phase 1 study of prasugrel in patients with sickle cell disease: effects on biomarkers of platelet activation and coagulation.

K. Winters, A. Frelinger, S. Jurcevic, 2014, Thrombosis research.

Altered sympathoadrenal response to dynamic exercise in cardiac transplant recipients.

M. Yacoub, N. Banner, A. Cox, 1989, Cardiovascular research.

Prolonged cardiac preservation. Evaluation of the University of Wisconsin preservation solution by comparison with the St. Thomas' Hospital cardioplegic solutions in the rat.

M. Yacoub, S. Ledingham, D. Lachno, 1990, Circulation.

The pharmacokinetics and pharmacodynamics of prasugrel in healthy Chinese, Japanese, and Korean subjects compared with healthy Caucasian subjects

K. Winters, P. Kothare, J. Jakubowski, 2010, European Journal of Clinical Pharmacology.

Effect of,f blockade on the neurohumoral and cardiopulmonary response to dynamic exercise in cardiac transplant recipients

N. Markandu, G. Sagnella, G. MacGregor, 2005 .

Determination of sixteen nucleotides, nucleosides and bases using high-performance liquid chromatography and its application to the study of purine metabolism in hearts for transplantation.

R. Smolenski, S. Ledingham, D. Lachno, 1990, Journal of chromatography.

Adenine nucleotide catabolism in human myocardium during heart and heart-lung transplantation.

M. Yacoub, R. Smolenski, D. Lachno, 1992, European Journal of Cardio-Thoracic Surgery.

Superior qualities of University of Wisconsin solution for ex vivo preservation of the pig heart.

M. Yacoub, N. Severs, S. Rothery, 1992, The Journal of thoracic and cardiovascular surgery.

The anal gland secretion of the European badger (Meles meles) and its role in social communication

T. Roper, J. Davies, D. Lachno, 1988 .

Dose-Dependent Inhibition of Human Platelet Aggregation by Prasugrel and its Interaction With Aspirin in Healthy Subjects

K. Winters, G. Weerakkody, J. Jakubowski, 2007, Journal of cardiovascular pharmacology.

Cardiac Transplant Recipients

N. Markandu, G. Sagnella, M. Miller, 2005 .

Blood pressure and endocrine responses to changes in dietary sodium intake in cardiac transplant recipients. Implications for the control of sodium balance.

M. Yacoub, F. Cappuccio, N. Markandu, 1994, Circulation.

Dihydroxyphenylglycol as a Biomarker of Norepinephrine Transporter Inhibition by Atomoxetine: Human Model to Assess Central and Peripheral Effects of Dosing

E. Ledent, P. Bieck, M. Leibowitz, 2016, Journal of clinical psychopharmacology.

A phase 1 study of prasugrel in patients with sickle cell disease: pharmacokinetics and effects on ex vivo platelet reactivity.

K. Winters, A. Frelinger, S. Jurcevic, 2013, British journal of clinical pharmacology.

Functional and metabolic effects of adenosine in cardioplegia: role of temperature and concentration.

M. Amrani, M. Yacoub, R. Smolenski, 1997, The Annals of thoracic surgery.

Beneficial effect of adenosine during reperfusion following prolonged cardioplegic arrest.

M. Yacoub, N. Patel, S. Ledingham, 1990, Cardiovascular research.

Formation and breakdown of uridine in ischemic hearts of rats and humans.

M. Yacoub, R. Smolenski, J. D. de Jong, 1993, Journal of molecular and cellular cardiology.

INCLUSION OF PATIENTS WITH ALZHEIMER'S DISEASE PATHOLOGY IN SOLANEZUMAB EXPEDITION 3 USING FLORBETAPIR PET IMAGING OR INNO-BIA ALZBIO3 CSF Aβ1-42

J. Trojanowski, E. Siemers, L. Shaw, 2014, Alzheimer's & Dementia.

Improved high-performance liquid chromatographic method for analysis of cyclosporin A using an automated sample processor.

M. Rose, D. Lachno, N. Patel, 1990, Journal of chromatography.

Salt Tolerance in the Halophyte Suaeda maritima L.Dum.: Abscisic Acid Concentrations in Response to Constant and Altered Salinity

T. Flowers, N. Clipson, D. Lachno, 1988 .

Stress induction of abscisic acid in maize roots

D. Baker, D. Lachno, D. Baker, 1986 .

Central pharmacodynamic activity of solanezumab in mild Alzheimer's disease dementia

E. Siemers, R. Dean, M. Case, 2018, Alzheimer's & dementia.

The effect of prasugrel on ADP-stimulated markers of platelet activation in patients with sickle cell disease

K. Winters, A. Frelinger, S. Jurcevic, 2015, Platelets.

Some effects of sodium chloride on cells of rice cultured in vitro

T. Flowers, S. A. Flowers, A. Yeo, 1985 .

Automated high-performance liquid chromatographic method for the analysis of two novel ergoline compounds in human plasma.

D. Lachno, B. Obermeyer, S. A. Brooks, 1997, Journal of chromatography. B, Biomedical sciences and applications.

Recommendations for adaptation and validation of commercial kits for biomarker quantification in drug development.

Lindsay King, Viswanath Devanarayan, Steve Keller, 2015, Bioanalysis.

The Effects of Mechanical Impedance to Growth on the Levels of ABA and IAA in Root Tips of Zea mays L.

L. Audus, R. Harrison-Murray, D. Lachno, 1982 .

The Use of 14C-Ethane Diol as a Quantitative Tracer for the Transpirational Volume Flow of Water and an Investigation of the Effects of Salinity upon Transpiration, Net Sodium Accumulation and Endogenous ABA in Individual Leaves of Oryza sativa L.

S. Caporn, T. Flowers, A. Yeo, 1985 .

Derivation of cutoffs for the Elecsys® amyloid β (1–42) assay in Alzheimer's disease

J. Trojanowski, E. Siemers, L. Shaw, 2018, Alzheimer's & dementia.

Validation of assays for measurement of amyloid-β peptides in cerebrospinal fluid and plasma specimens from patients with Alzheimer's disease treated with solanezumab.

H. Vanderstichele, R. Dean, R. Demattos, 2013, Journal of Alzheimer's disease : JAD.

Common polymorphisms of CYP2C19 and CYP2C9 affect the pharmacokinetic and pharmacodynamic response to clopidogrel but not prasugrel

S. Iturria, K. Winters, C. Ernest, 2007, Journal of thrombosis and haemostasis : JTH.

Validation of a multiplex assay for simultaneous quantification of amyloid-β peptide species in human plasma with utility for measurements in studies of Alzheimer's disease therapeutics.

H. Vanderstichele, R. Dean, F. Martényi, 2012, Journal of Alzheimer's disease : JAD.

New fluorescent derivatives of cyclosporin for use in immunoassays.

J. Miller, N. J. Seare, D. Lachno, 1992, Journal of pharmaceutical and biomedical analysis.

Preservation of nucleotide pool during heart transplantation and evaluation of adenylate catabolic pathways in the human heart.

M. Yacoub, A. Suitters, R. Smolenski, 1991, Advances in experimental medicine and biology.

A digital enzyme-linked immunosorbent assay for ultrasensitive measurement of amyloid-β 1–42 peptide in human plasma with utility for studies of Alzheimer’s disease therapeutics

R. Dean, A. Jeromin, J. Dage, 2016, Alzheimer's Research & Therapy.

A digital enzyme-linked immunosorbent assay for ultrasensitive measurement of amyloid-β 1–42 peptide in human plasma with utility for studies of Alzheimer’s disease therapeutics

R. Dean, A. Jeromin, J. Dage, 2016, Alzheimer's Research & Therapy.

Validation of ELISA methods for quantification of total tau and phosporylated-tau181 in human cerebrospinal fluid with measurement in specimens from two Alzheimer's disease studies.

E. Siemers, H. Vanderstichele, R. Dean, 2011, Journal of Alzheimer's disease : JAD.

Effects of Duloxetine on Norepinephrine and Serotonin Transporter Activity in Healthy Subjects

M. Detke, C. Nemeroff, R. Dean, 2014, Journal of clinical psychopharmacology.

DERIVING A CUT-OFF FOR THE ELECSYS® β-AMYLOID (1–42) IMMUNOASSAY FOR USE IN CLINICAL TRIALS SUPPORTED BY ELI LILLY FOR PATIENTS WITH CLINICALLY DEFINED ALZHEIMER’S DISEASE (AD)

J. Trojanowski, E. Siemers, L. Shaw, 2017, Alzheimer's & Dementia.

Prospective quality-control monitoring in the context of a clinical trial

J. Trojanowski, E. Siemers, L. Shaw, 2015, Alzheimer's & Dementia.

Validation and Clinical Utility of ELISA Methods for Quantification of Amyloid-β of Peptides in Cerebrospinal Fluid Specimens from Alzheimer’s Disease Studies.

R. Dean, B. Willis, M. Vandijck, 2015, Journal of Alzheimer's disease : JAD.

The influence of matrix type, diurnal rhythm and sample collection and processing on the measurement of plasma β-amyloid isoforms using the INNO-BIA plasma Aβ forms multiplex assay

E. Siemers, H. Vanderstichele, R. Dean, 2009, The journal of nutrition, health & aging.

Changes of Urine Dihydroxyphenylglycol to Norepinephrine Ratio in Children With Attention-Deficit Hyperactivity Disorder (ADHD) Treated With Atomoxetine

J. Alda, A. Montoya, I. Gilaberte, 2011, Journal of child neurology.

Measurement of cerebrospinal fluid total tau and phospho-tau in phase 2 trials of therapies targeting Aβ

E. Siemers, R. Dean, G. Sethuraman, 2009, Alzheimer's & Dementia.