Jeanette Reinshagen

发表

Identification of inhibitors of SARS-CoV-2 in-vitro cellular toxicity in human (Caco-2) cells using a large scale drug repurposing collection

S. Ciesek, J. Cinatl, D. Bojkova, 2020 .

A Label-Free Continuous Fluorescence-Based Assay for Monitoring Ornithine Decarboxylase Activity with a Synthetic Putrescine Receptor

E. Schwedhelm, W. Nau, Mohamed Nilam, 2017, SLAS discovery : advancing life sciences R & D.

Accelerating Drug Discovery Efforts for Trypanosomatidic Infections Using an Integrated Transnational Academic Drug Discovery Platform

Maria Paola Costi, R. Wade, M. Bolognesi, 2019, SLAS discovery : advancing life sciences R & D.

Identification of inhibitors of SARS-CoV-2 3CL-Pro enzymatic activity using a small molecule in-vitro repurposing screen

F. Musiani, Daniela Iaconis, V. Summa, 2020, bioRxiv.

Development of a Colorimetric and a Fluorescence Phosphatase-Inhibitor Assay Suitable for Drug Discovery Approaches

T. Eschenhagen, B. Ellinger, A. El-Armouche, 2013, Journal of biomolecular screening.

A method for the rational selection of drug repurposing candidates from multimodal knowledge harmonization

M. Peitsch, R. Eils, H. Fröhlich, 2021, Scientific Reports.

Cytopathic SARS-CoV-2 screening on VERO-E6 cells in a large-scale repurposing effort

C. Collard, Daniela Iaconis, V. Summa, 2022, Scientific data.

SAR Studies and Biological Characterization of a Chromen-4-one Derivative as an Anti-Trypanosoma brucei Agent.

Maria Paola Costi, S. Gul, G. Ponterini, 2019, ACS medicinal chemistry letters.

Discovery of a benzothiophene-flavonol halting miltefosine and antimonial drug resistance in Leishmania parasites through the application of medicinal chemistry, screening and genomics.

Maria Paola Costi, S. Gul, G. Ponterini, 2019, European journal of medicinal chemistry.

Development and implementation of a cell-based assay to discover agonists of the nuclear receptor REV-ERBα

S. Gul, B. Staels, H. Duez, 2018, Journal of biological methods.

Development and implementation of a cell-based assay to discover agonists of the nuclear receptor REVERB α

S. Gul, B. Staels, H. Duez, 2018 .

A SARS-CoV-2 cytopathicity dataset generated by high-content screening of a large drug repurposing collection

S. Ciesek, J. Cinatl, D. Bojkova, 2021, Scientific Data.

A SARS-CoV-2 cytopathicity dataset generated by high-content screening of a large drug repurposing collection

S. Ciesek, J. Cinatl, D. Bojkova, 2021, Scientific data.

Establishing the Secondary Metabolite Profile of the Marine Fungus: Tolypocladium geodes sp. MF458 and Subsequent Optimisation of Bioactive Secondary Metabolite Production

J. Imhoff, J. Rahlff, S. Wrigley, 2017, Marine Drugs.

A High-Throughput HIV-1 Drug Screening Platform, Based on Lentiviral Vectors and Compatible with Biosafety Level-1

V. Prassolov, B. Fehse, C. Stocking, 2020, Viruses.

A Drug Repositioning Approach Identifies a Combination of Compounds as a Potential Regimen for Chronic Lymphocytic Leukemia Treatment

S. Gul, A. Mashhour, M. Boudjelal, 2021, Frontiers in Oncology.

The COVID-19 PHARMACOME: Rational Selection of Drug Repurposing Candidates from Multimodal Knowledge Harmonization

Martin Hofmann-Apitius, Andrea Zaliani, Reagon Karki, 2020, bioRxiv.

Profiling of Flavonol Derivatives for the Development of Antitrypanosomatidic Drugs.

Maria Paola Costi, R. Wade, S. Gul, 2016, Journal of medicinal chemistry.

A hybrid approach unveils drug repurposing candidates targeting an Alzheimer pathophysiology mechanism

M. Hofmann-Apitius, C. Ebeling, S. Gebel, 2022, Patterns.

Activation of Caspase-6 Is Promoted by a Mutant Huntingtin Fragment and Blocked by an Allosteric Inhibitor Compound.

D. Ehrnhoefer, M. Hayden, A. Renslo, 2019, Cell chemical biology.

Methoxylated 2'-hydroxychalcones as antiparasitic hit compounds.

Maria Paola Costi, S. Gul, L. Costantino, 2017, European journal of medicinal chemistry.

A screening strategy for the discovery of drugs that reduce C/EBPβ-LIP translation with potential calorie restriction mimetic properties

C. Calkhoven, C. Müller, O. Pless, 2017, Scientific Reports.

Exploiting the 2-Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery

Maria Paola Costi, R. Wade, W. Hunter, 2017, ACS omega.

Identification of Inhibitors of SARS-CoV-2 3CL-Pro Enzymatic Activity Using a Small Molecule in Vitro Repurposing Screen

F. Musiani, Daniela Iaconis, V. Summa, 2021, ACS pharmacology & translational science.

Identification of Small-Molecule Frequent Hitters from AlphaScreen High-Throughput Screens

Igor V. Tetko, Jeanette Reinshagen, Kenji Schorpp, 2014, Journal of biomolecular screening.

The novel coronary artery disease risk factor ADAMTS-7 modulates atherosclerotic plaque formation by degradation of TIMP-1

J. Erdmann, H. Schunkert, J. Bernhagen, 2023, bioRxiv.

Identification of inhibitors of SARS-CoV-2 3CL-Pro enzymatic activity using a small molecule in-vitro repurposing screen

F. Musiani, Daniela Iaconis, J. Neyts, 2020 .

Identification of Inhibitors of SARS-CoV-2 3CL-Pro Enzymatic Activity Using a Small Molecule in Vitro Repurposing Screen

F. Musiani, Daniela Iaconis, J. Neyts, 2021, ACS Pharmacology & Translational Science.

Exploiting the 2-Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery

Ulrike Wittig, S. Mangani, V. Hannaert, 2017, ACS omega.

High-Throughput Phenotypic Screening and Machine Learning Methods Enabled the Selection of Broad-Spectrum Low-Toxicity Antitrypanosomatidic Agents

Kimberley M. Zorn, Daniel H. Foil, S. Ekins, 2023, Journal of medicinal chemistry.

Drug repurposing screen to identify inhibitors of the RNA polymerase (nsp12) and helicase (nsp13) from SARS-CoV-2 replication and transcription complex

Daniela Iaconis, E. Tramontano, A. Beccari, 2024, Virus research.

Resolving the pharmacological redox-sensitivity of SARS-CoV-2 PLpro in drug repurposing screening enabled identification of the competitive GRL-0617 binding site inhibitor CPI-169

S. Grdadolnik, J. Plavec, Daniela Iaconis, 2023, bioRxiv.

A Bioluminogenic HDAC Activity Assay

Nathan J. Evans, S. Gul, A. Niles, 2011, Journal of biomolecular screening.