D. Zeng

发表

Bone Marrow NK1.1− and NK1.1+ T Cells Reciprocally Regulate Acute Graft versus Host Disease

M. Garcia-Ojeda, S. Strober, R. Sibley, 1999, The Journal of experimental medicine.

graft-versus-host disease with autoimmune manifestations T and B cells in transplants induce chronic + Donor CD4

I. Todorov, F. Kandeel, S. Forman, 2011 .

Donor CD4+ T and B cells in transplants induce chronic graft-versus-host disease with autoimmune manifestations.

I. Todorov, F. Kandeel, S. Forman, 2006, Blood.

Extrafollicular CD4+ T-B interactions are sufficient for inducing autoimmune-like chronic graft-versus-host disease

Hua Yu, Xiwei Wu, M. Muschen, 2017, Nature Communications.

In vivo activated CD103 + CD4 + Regulatory T Cells Ameliorate Ongoing Chronic GVHD

T. Yi, I. Todorov, F. Kandeel, 2008 .

Administration of anti-CD20 mAb is highly effective in preventing but ineffective in treating chronic graft-versus-host disease while preserving strong graft-versus-leukemia effects.

Tao Wu, S. Forman, K. Cassady, 2014, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Administration Of Anti-CD20 Mab Is Highly Effective In Preventing But Ineffective In Treating Chronic GVHD While Preserving A Strong GVL Effect

Tao Wu, S. Forman, Jeremy J. Racine, 2013 .

Growth factors and medium hyperglycemia induce Sox9+ ductal cell differentiation into β cells in mice with reversal of diabetes

A. Riggs, Mingfeng Zhang, C. Chen, 2016, Proceedings of the National Academy of Sciences.

Antibodies from donor B cells perpetuate cutaneous chronic graft-versus-host disease in mice.

Mingfeng Zhang, S. Forman, James S. Young, 2016, Blood.

T helper 2-dominant antilymphoma immune response is associated with fatal outcome.

D. Umetsu, N. Chao, Y. Chen, 1997, Blood.

Granulocyte colony-stimulating factor reduces the capacity of blood mononuclear cells to induce graft-versus-host disease: impact on blood progenitor cell transplantation.

S. Strober, D. Zeng, S. Dejbakhsh-Jones, 1997, Blood.

Mixed Chimerism and Growth Factors Augment β Cell Regeneration and Reverse Late-Stage Type 1 Diabetes

Brian J. Wilson, M. Atkinson, I. Todorov, 2012, Science Translational Medicine.

Regulation of GVHD and GVL Activity via PD-L1 Interaction With PD-1 and CD80

Paul J. Martin, K. Cassady, D. Zeng, 2018, Front. Immunol..

MHC-mismatched mixed chimerism augments thymic regulatory T-cell production and prevents relapse of EAE in mice

A. Riggs, Mingfeng Zhang, K. Cassady, 2015, Proceedings of the National Academy of Sciences.

Host APCs Augment In Vivo Expansion of Donor Natural Regulatory T Cells via B7H1/B7.1 in Allogeneic Recipients

Lieping Chen, T. Yi, I. Todorov, 2011, The Journal of Immunology.

Allogeneic Recipients Natural Regulatory T Cells via B7H1/B7.1 in Host APCs Augment In Vivo Expansion of Donor

Lieping Chen, I. Todorov, S. Forman, 2011 .

Predominance of NK1.1+TCR alpha beta+ or DX5+TCR alpha beta+ T cells in mice conditioned with fractionated lymphoid irradiation protects against graft-versus-host disease: "natural suppressor" cells.

P. Huie, S. Strober, D. Zeng, 2001, Journal of immunology.

Predominance of NK1.1+TCRαβ+ or DX5+TCRαβ+ T Cells in Mice Conditioned with Fractionated Lymphoid Irradiation Protects Against Graft-Versus-Host Disease: “Natural Suppressor” Cells1

P. Huie, S. Strober, D. Zeng, 2001, The Journal of Immunology.

Retention of Donor T Cells in Lymphohematopoietic Tissue and Augmentation of Tissue PD-L1 Protection for Prevention of GVHD While Preserving GVL Activity

Ubaydah Nasri, P. Martin, R. Nakamura, 2022, Frontiers in Immunology.

Depletion of host CCR7(+) dendritic cells prevented donor T cell tissue tropism in anti-CD3-conditioned recipients.

Wei He, S. Forman, Can Liu, 2014, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Anti-CD3 preconditioning separates GVL from GVHD via modulating host dendritic cell and donor T-cell migration in recipients conditioned with TBI.

T. Yi, I. Todorov, F. Kandeel, 2009, Blood.

Donor CD8+ T Cells Mediate Graft-versus-Leukemia Activity without Clinical Signs of Graft-versus-Host Disease in Recipients Conditioned with Anti-CD3 Monoclonal Antibody1

C. Contag, I. Todorov, F. Kandeel, 2007, The Journal of Immunology.

Monoclonal Antibody Recipients Conditioned with Anti-CD3 Clinical Signs of Graft-versus-Host Disease in Graft-versus-Leukemia Activity without T Cells Mediate + Donor CD8

C. Contag, I. Todorov, F. Kandeel, 2006 .

Donor CD8+ T cells facilitate induction of chimerism and tolerance without GVHD in autoimmune NOD mice conditioned with anti-CD3 mAb.

M. Atkinson, I. Todorov, F. Kandeel, 2004, Blood.

Induction of Mixed Chimerism for Reversal of Autoimmunity in Type 1 Diabetes

Jeremy J. Racine, D. Zeng, 2011 .

Induction of Mixed Chimerism With MHC-Mismatched but Not Matched Bone Marrow Transplants Results in Thymic Deletion of Host-Type Autoreactive T-Cells in NOD Mice

M. Atkinson, I. Todorov, Jeremy J. Racine, 2011, Diabetes.

Induction of Chimerism Permits Low-Dose Islet Grafts in the Liver or Pancreas to Reverse Refractory Autoimmune Diabetes

M. Atkinson, I. Todorov, I. Nair, 2010, Diabetes.

Elimination of insulitis and augmentation of islet β cell regeneration via induction of chimerism in overtly diabetic NOD mice

M. Atkinson, I. Todorov, F. Kandeel, 2007, Proceedings of the National Academy of Sciences.

Induction of Mixed Chimerism Depletes Pre-existing and De Novo–Developed Autoreactive B Cells in Autoimmune NOD Mice

Mingfeng Zhang, Jeremy J. Racine, D. Zeng, 2014, Diabetes.

tolerance in bone marrow transplantation in mice PG27, an extract of Tripterygium wilfordii hook f, induces antigen-specific

N. Chao, J. Fidler, D. Zeng, 2013 .

PG27, an extract of Tripterygium wilfordii hook f, induces antigen-specific tolerance in bone marrow transplantation in mice.

N. Chao, J. Fidler, Y. Chen, 2000, Blood.

MHC-Mismatched Chimerism Is Required for Induction of Transplantation Tolerance in Autoimmune Nonobese Diabetic Recipients

Mingfeng Zhang, Tao Wu, R. Deng, 2014, The Journal of Immunology.

Autoimmune Nonobese Diabetic Recipients in for Induction of Transplantation Tolerance MHC-Mismatched Chimerism Is Required

Mingfeng Zhang, Tao Wu, R. Deng, 2014 .

Murine Models Provide New Insights Into Pathogenesis of Chronic Graft-Versus-Host Disease in Humans

Paul J. Martin, D. Zeng, Qingxiao Song, 2021, Frontiers in Immunology.

Cutting Edge: A Role for CD1 in the Pathogenesis of Lupus in NZB/NZW Mice1

S. Strober, A. Brendolan, J. Tung, 2000, The Journal of Immunology.

Bone Marrow NK1.1− and NK1.1+ T Cells Reciprocally Regulate Acute Graft versus Host Disease

S. Strober, R. Sibley, D. Zeng, 1999, The Journal of experimental medicine.

Newly found arsons ignite the fire of gut GVHD.

D. Zeng, 2018, The Journal of clinical investigation.

Characterization of novel antigens recognized by serum autoantibodies from anti‐CD1 TCR‐transgenic lupus mice

W. Robinson, P. Utz, W. Hueber, 2004, European journal of immunology.

Interferon-α–inducible proteins are novel autoantigens in murine lupus

P. Utz, W. Hueber, S. Strober, 2004 .

Tissue-resident PSGL1loCD4+ T cells promote B cell differentiation and chronic graft-versus-host-disease-associated autoimmunity.

A. Riggs, Xiwei Wu, K. Haas, 2020, The Journal of clinical investigation.

Subsets of Transgenic T Cells That Recognize CD1 Induce or Prevent Murine Lupus: Role of Cytokines

P. Huie, S. Strober, R. Sibley, 1998, The Journal of experimental medicine.

HDAC inhibitor reduces cytokine storm and facilitates induction of chimerism that reverses lupus in anti-CD3 conditioning regimen

I. Todorov, F. Kandeel, S. Forman, 2008, Proceedings of the National Academy of Sciences.

Double Negative (CD4−CD8−αβ+) T Cells Which Promote Tolerance Induction and Regulate Autoimmunity

S. Strober, R. Sibley, Lirong Cheng, 1996, Immunological reviews.

Tolerogenic anti-IL-2 mAb prevents graft-versus-host disease while preserving strong graft-versus-leukemia activity.

A. Riggs, Xiwei Wu, Paul J. Martin, 2021, Blood.

B7H1/CD80 Interaction Augments PD-1–Dependent T Cell Apoptosis and Ameliorates Graft-versus-Host Disease

Mingfeng Zhang, Lieping Chen, Sheng Yao, 2015, The Journal of Immunology.

Graft-versus-Host Disease Dependent T Cell Apoptosis and Ameliorates - B7H1/CD80 Interaction Augments PD-1

Mingfeng Zhang, Lieping Chen, Sheng Yao, 2014 .

- tumor cells express both CD8 and T-cell antigen receptor Allogeneic bone marrow cells that facilitate complete chimerism and eliminate

P. Huie, S. Strober, D. Zeng, 2013 .

Immune Tolerance to Combined Organ and Bone Marrow Transplants After Fractionated Lymphoid Irradiation Involves Regulatory NK T Cells and Clonal Deletion1

M. Taniguchi, S. Strober, J. Shizuru, 2002, The Journal of Immunology.

Allogeneic bone marrow cells that facilitate complete chimerism and eliminate tumor cells express both CD8 and T-cell antigen receptor–αβ

P. Huie, S. Strober, D. Zeng, 2001 .

Allogeneic bone marrow cells that facilitate complete chimerism and eliminate tumor cells express both CD 8 and T-cell antigen receptor – ab

P. Huie, S. Strober, D. Zeng, 2001 .

MHC-Mismatched Mixed Chimerism Mediates Thymic Deletion of Cross-Reactive Autoreactive T Cells and Prevents Insulitis in Nonobese Diabetic Mice

Mingfeng Zhang, Jeremy J. Racine, D. Zeng, 2015, The Journal of Immunology.

Autoreactive T Cells and Prevents Insulitis in Mediates Thymic Deletion of Cross-Reactive MHC-Mismatched Mixed Chimerism

Mingfeng Zhang, Jeremy J. Racine, D. Zeng, 2014 .

This information is current as T Cells + and CD 8 + CD 4 Graft-versus-Host Disease Caused by Donor Selection , and Development of Chronic Thymic Damage , Impaired Negative

I. Todorov, Tao Wu, James S. Young, 2013 .

Donor B Cells in Transplants Augment Clonal Expansion and Survival of Pathogenic CD4+ T Cells That Mediate Autoimmune-like Chronic Graft-versus-Host Disease

T. Yi, I. Todorov, Tao Wu, 2012, The Journal of Immunology.

Alloimmune Response Results in Expansion of Autoreactive Donor CD4+ T Cells in Transplants That Can Mediate Chronic Graft-versus-Host Disease

P. Chu, T. Yi, I. Todorov, 2011, The Journal of Immunology.

Mechanisms of tolerance to rat heart allografts using posttransplant TLI. Changes in cytokine expression.

P. Huie, D. Yin, S. Strober, 1996, Transplantation.

Response: Is CD103 a good surface marker for in vivo–activated effector/memory Treg cells in patients with chronic inflammation? Unknown yet

Dongchang Zhao, R. Nakamura, D. Zeng, 2009 .

Host conditioning with total lymphoid irradiation and antithymocyte globulin prevents graft-versus-host disease: the role of CD1-reactive natural killer T cells.

S. Strober, D. Zeng, F. Lan, 2003, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Donor blood monocytes but not T or B cells facilitate long-term allograft survival after total lymphoid irradiation.

D. Bloch, P. Huie, E. Engleman, 1998, Transplantation.

PD-L 1 interacts with CD 80 to regulate graft-versus-leukemia activity of donor CD 8 + T cells

Mingfeng Zhang, Haidong Dong, S. Forman, 2018 .

PD-L1 interacts with CD80 to regulate graft-versus-leukemia activity of donor CD8+ T cells

Mingfeng Zhang, Haidong Dong, S. Forman, 2017, The Journal of clinical investigation.

Heterogeneity of NK1.1+ T cells in the bone marrow: divergence from the thymus.

S. Snapper, S. Balk, M. Taniguchi, 1999, Journal of immunology.

Loss of B7-H1 Expression by Recipient Parenchymal Cells Leads to Expansion of Infiltrating Donor CD8+ T Cells and Persistence of Graft-Versus-Host Disease

Lieping Chen, Z. Meng, Wei He, 2012, The Journal of Immunology.

DiseaseAutoimmune-like Chronic Graft-versus-Host T Cells That Mediate + CD4 Pathogenic Clonal Expansion and Survival of Donor B Cells in Transplants Augment

T. Yi, I. Todorov, James S. Young, 2012 .

Persistence of Graft-Versus-Host Disease T Cells and + Infiltrating Donor CD 8 Parenchymal Cells Leads to Expansion of Loss of B 7-H 1 Expression by Recipient

Lieping Chen, Z. Meng, Wei He, 2011 .

Thymic Damage, Impaired Negative Selection, and Development of Chronic Graft-versus-Host Disease Caused by Donor CD4+ and CD8+ T Cells

I. Todorov, Tao Wu, James S. Young, 2013, The Journal of Immunology.

Dual-responsive mesoporous poly-N-isopropylacrylamide-hydroxyapatite composite microspheres for controlled anticancer drug delivery

Ting Shu, Yulin Zhang, Liang Zhou, 2021, Journal of Sol-Gel Science and Technology.

Absence of donor Th17 leads to augmented Th1 differentiation and exacerbated acute graft-versus-host disease.

T. Yi, I. Todorov, F. Kandeel, 2008, Blood.

MHC-mismatched mixed chimerism restores peripheral tolerance of noncross-reactive autoreactive T cells in NOD mice

A. Riggs, Mingfeng Zhang, Shanshan Tang, 2018, Proceedings of the National Academy of Sciences.

Bridge between type 1 diabetes in mouse and man

D. Zeng, 2017, Proceedings of the National Academy of Sciences.

IL-17 can promote tumor growth through an IL-6–Stat3 signaling pathway

Hua Yu, M. Kortylewski, D. Pardoll, 2009, The Journal of experimental medicine.

Reciprocal differentiation and tissue-specific pathogenesis of Th1, Th2, and Th17 cells in graft-versus-host disease.

Lieping Chen, D. Umetsu, Y. Iwakura, 2009, Blood.

Donor cells that facilitate tolerance to rat heart allografts after posttransplant total lymphoid irradiation and rabbit anti-thymocyte globulin.

S. Strober, K. Hayamizu, D. Zeng, 1999, Transplantation proceedings.

Mechanisms of Tolerance

S. Strober, D. Zeng, 2016 .

IL-22-dependent dysbiosis and mononuclear phagocyte depletion contribute to steroid-resistant gut graft-versus-host disease in mice

A. Riggs, R. Jenq, M. V. D. van den Brink, 2021, Nature Communications.

In vivo-activated CD103+CD4+ regulatory T cells ameliorate ongoing chronic graft-versus-host disease.

T. Yi, I. Todorov, F. Kandeel, 2007, Blood.

Radiation-Free Anti-CD3-Conditioning Regimen Maintains Tissue Protection Mechanisms and Prevents GVHD: Role of Tissue Expression of B7H1

Lieping Chen, S. Forman, D. Zeng, 2008 .

Unique patterns of surface receptors, cytokine secretion, and immune functions distinguish T cells in the bone marrow from those in the periphery: impact on allogeneic bone marrow transplantation.

P. Huie, P. Hoffmann, S. Strober, 2002, Blood.

Suppressor ' ' Cells Against Graft-Versus-Host Disease : ' ' Natural Fractionated Lymphoid Irradiation Protects T Cells in Mice Conditioned with + βα TCR + or DX 5 + βα TCR + Predominance of NK 1 . 1

P. Huie, S. Strober, D. Zeng, 2001 .

Extrafollicular CD4+ T-B interactions are sufficient for inducing autoimmune-like chronic graft-versus-host disease

Hua Yu, Xiwei Wu, M. Muschen, 2017, Nature Communications.

Reversal of autoimmunity by mixed chimerism enables reactivation of β cells and transdifferentiation of α cells in diabetic NOD mice

A. Riggs, Mingfeng Zhang, Shanshan Tang, 2020, Proceedings of the National Academy of Sciences.

Activation of natural killer T cells in NZB/W mice induces Th1-type immune responses exacerbating lupus.

M. Kronenberg, S. Strober, Yinping Liu, 2003, The Journal of clinical investigation.

Stephen chronic GVHD regulatory T cells ameliorate ongoing + CD 4 + activated CD 103 In vivo

T. Yi, I. Todorov, F. Kandeel, 2008 .

In vivo – activated CD 103 CD 4 regulatory T cells ameliorate ongoing chronic graft-versus-host disease

T. Yi, I. Todorov, F. Kandeel, 2008 .

Steroid-Refractory Gut Graft-Versus-Host Disease: What We Have Learned From Basic Immunology and Experimental Mouse Model

Ubaydah Nasri, D. Zeng, Qingxiao Song, 2022, Frontiers in Immunology.

Haploidentical mixed chimerism cures autoimmunity in established type 1 diabetic mice.

A. Riggs, Mingfeng Zhang, Ubaydah Nasri, 2020, The Journal of clinical investigation.

Suppression of graft-versus-host disease by naturally occurring regulatory T cells.

P. Hoffmann, S. Strober, D. Zeng, 2004, Transplantation.

Marrow: Divergence from the Thymus Heterogeneity of NK1.1+ T Cells in the Bone

S. Snapper, M. Taniguchi, S. Strober, 2013 .

Mouse models usher in precision medicine.

D. Zeng, 2020, Blood.

Mutual Activation and Expansion of Donor CD4 + T Cells and B Cells in Transplants Play a Critical Role in the Initiation of Chronic Graft-Versus-Host Disease.

T. Yi, James S. Young, Dongchang Zhao, 2009 .

Granulocyte colony-stimulating factor reduces the capacity of blood mononuclear cells to induce graft-versus-host disease: impact on blood progenitor cell transplantation.

S. Strober, D. Zeng, S. Dejbakhsh-Jones, 1997, Blood.

microRNA-142 guards against autoimmunity by controlling Treg cell homeostasis and function

M. Boldin, C. Ouyang, K. Cassady, 2022, PLoS biology.

The Investigation on Nosocomial Infection of Acinetobacter baumannii and the Clinical Analysis of Sequential Therapy of Cefoperazone/Sulbactam Sodium for Intracranial Infection

D. Zeng, Shilong Shen, Zezhong Xiong, 2022, Computational and mathematical methods in medicine.

Engineering CpG island DNA methylation in pluripotent cells through synthetic CpG-free ssDNA insertion

Jinhui Wang, Rama Natarajan, Xiwei Wu, 2023, Cell reports methods.

Clonable progenitors committed to the T lymphocyte lineage in the mouse bone marrow; use of an extrathymic pathway

S. Strober, D. Zeng, S. Dejbakhsh-Jones, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Blockade of trans PD-L1 interaction with CD80 augments antitumor immunity

Dustin E. Schones, A. Riggs, yang-xin fu, 2023, Proceedings of the National Academy of Sciences of the United States of America.

Th17 cell-derived amphiregulin promotes colitis-associated intestinal fibrosis through activation of mTOR and MEK in intestinal myofibroblasts.

W. Koltun, H. Yang, Y. Cong, 2022, Gastroenterology.

Different patterns of TCR transgene expression in single-positive and double-negative T cells. Evidence for separate pathways of T cell maturation.

R. Liblau, S. Strober, D. Zeng, 1996, Journal of immunology.

Allogeneic bone marrow cells that facilitate complete chimerism and eliminate tumor cells express both CD8 and T-cell antigen receptor-alphabeta.

P. Huie, S. Strober, D. Zeng, 2001, Blood.

Sirolimus Is Effective in Refractory Immune Thrombocytopenia: Results of an Open-Label Prospective Multicenter Trial in China

X. Peng, Hong Liu, Lei Gao, 2017 .

Trafficking between clonally related peripheral T helper cells and tissue-resident T helper cells in chronic GVHD.

Xiwei Wu, Ubaydah Nasri, A. Salhotra, 2022, Blood.

Chronic GvHD NIH Consensus Project Biology Task Force: evolving path to personalized treatment of chronic GvHD

J. Ritz, Stephanie J. Lee, S. Paczesny, 2022, Blood advances.

Donor PD-L1 is required for organ transplant tolerance in MHC-mismatched mixed chimeras while PD-L1 and MHCII are not required for inducing chimerism.

A. Riggs, Xiwei Wu, A. Chong, 2023, American Journal of Transplantation.

Donor T cell STAT3 deficiency enables tissue PD-L1–dependent prevention of graft-versus-host disease while preserving graft-versus-leukemia activity

D. Levy, Xiwei Wu, Ubaydah Nasri, 2023, The Journal of clinical investigation.

Administration Of Anti-CD20 mAb Is Highly Effective In Preventing But Ineffective In Treating Chronic GVHD While Preserving Strong GVL Effects

Tao Wu, S. Forman, Jeremy J. Racine, 2014 .

Newly found arsons ignite the fire of gut GVHD.

D. Zeng, 2018, The Journal of clinical investigation.

Depletion of host CCR7(+) dendritic cells prevented donor T cell tissue tropism in anti-CD3-conditioned recipients.

Wei He, S. Forman, Can Liu, 2014, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

This information is current as Persistence of Graft-Versus-Host Disease Infiltrating Donor CD8+ T Cells and Parenchymal Cells Leads to Expansion of Loss of B7-H1 Expression by Recipient

R. Deng, D. Zeng, Miao Wang, 2013 .

Interferon-alpha-inducible proteins are novel autoantigens in murine lupus.

P. Utz, W. Hueber, S. Strober, 2004, Arthritis and rheumatism.

Regulators help new immigrants settle down?

D. Zeng, 2014, Blood.