M. Cherney

发表

The crystal and molecular structures of a cathepsin K:chondroitin sulfate complex.

M. James, D. Brömme, Zhenqiang Li, 2008, Journal of molecular biology.

Crystal Structures of the Main Peptidase from the SARS Coronavirus Inhibited by a Substrate-like Aza-peptide Epoxide

M. James, L. Eltis, Jie Liu, 2005, Journal of Molecular Biology.

The structures of Thermoplasma volcanium phosphoribosyl pyrophosphate synthetase bound to ribose-5-phosphate and ATP analogs.

M. James, Maia M Cherney, Leonid T Cherney, 2011, Journal of molecular biology.

Quaternary structure of WzzB and WzzE polysaccharide copolymerases

M. Cygler, I. Rouiller, M. Bostina, 2015, Protein science : a publication of the Protein Society.

Expression, purification, crystallization and preliminary X-ray analysis of two arginine-biosynthetic enzymes from Mycobacterium tuberculosis.

M. James, L. Cherney, C. Garen, 2006, Acta crystallographica. Section F, Structural biology and crystallization communications.

Expression, purification, crystallization and preliminary X-ray analysis of Rv3117, a probable thiosulfate sulfurtransferase (CysA3) from Mycobacterium tuberculosis.

M. James, R. Sankaranarayanan, L. Cherney, 2008, Acta crystallographica. Section F, Structural biology and crystallization communications.

The molecular structure of Rv2074, a probable pyridoxine 5'-phosphate oxidase from Mycobacterium tuberculosis, at 1.6 angstroms resolution.

M. James, C. Garen, M. Cherney, 2006, Acta crystallographica. Section F, Structural biology and crystallization communications.

Crystal Structure of Human β-Hexosaminidase B: Understanding the Molecular Basis of Sandhoff and Tay–Sachs Disease

M. James, B. Mark, S. Knapp, 2018 .

The structure of the arginine repressor from Mycobacterium tuberculosis bound with its DNA operator and Co-repressor, L-arginine.

M. James, L. Cherney, C. Garen, 2009, Journal of molecular biology.

An Episulfide Cation (Thiiranium Ring) Trapped in the Active Site of HAV 3C Proteinase Inactivated by Peptide-based Ketone Inhibitors

J. Vederas, M. James, L. Eltis, 2006, Journal of Molecular Biology.

Preliminary X-ray crystallographic analysis of sulfide:quinone oxidoreductase from Acidithiobacillus ferrooxidans.

M. James, Jianshe Liu, M. Solomonson, 2009, Acta crystallographica. Section F, Structural biology and crystallization communications.

High throughput crystallography of TB drug targets.

D. Eisenberg, J. Berger, M. James, 2007, Infectious disorders drug targets.

Shiga toxin type 2

M. James, M. Fujinaga, M. Fraser, 2004 .

Preliminary X-ray crystallographic analysis of ornithine acetyltransferase (Rv1653) from Mycobacterium tuberculosis.

M. James, R. Sankaranarayanan, C. Garen, 2009, Acta crystallographica. Section F, Structural biology and crystallization communications.

Crystal Structure of the Tumor-promoter Okadaic Acid Bound to Protein Phosphatase-1*

M. James, K. Bateman, C. Holmes, 2001, The Journal of Biological Chemistry.

Crystal Structures of Active and Inactive Conformations of a Caliciviral RNA-dependent RNA Polymerase*

M. James, K. Ng, F. Parra, 2002, The Journal of Biological Chemistry.

Crystal structure of human beta-hexosaminidase B: understanding the molecular basis of Sandhoff and Tay-Sachs disease.

M. James, B. Mark, S. Knapp, 2003, Journal of molecular biology.

Structural study of the complex between human pepsin and a phosphorus-containing peptidic -transition-state analog.

M. James, M. Fujinaga, N. Tarasova, 2000, Acta crystallographica. Section D, Biological crystallography.

Structural details of a calcium-induced molecular switch: X-ray crystallographic analysis of the calcium-saturated N-terminal domain of troponin C at 1.75 A resolution.

M. James, N. Strynadka, L. Smillie, 1997, Journal of molecular biology.

Crystal structure of LL-diaminopimelate aminotransferase from Arabidopsis thaliana: a recently discovered enzyme in the biosynthesis of L-lysine by plants and Chlamydia.

J. Vederas, M. James, M. Flegel, 2007, Journal of molecular biology.

Structural characterization of activation ‘intermediate 2’ on the pathway to human gastricsin

M. James, N. Tarasova, Amir R. Khan, 1997, Nature Structural Biology.

Crystal Structure of LexA A Conformational Switch for Regulation of Self-Cleavage

Richard A. Pfuetzner, John W. Little, R. Pfuetzner, 2001, Cell.

Structure-Activity Analysis of Cathepsin K/Chondroitin 4-Sulfate Interactions*

M. James, D. Brömme, F. Lecaille, 2010, The Journal of Biological Chemistry.

Non-nucleoside Analogue Inhibitors Bind to an Allosteric Site on HCV NS5B Polymerase

Meitian Wang, M. James, K. Ng, 2003, The Journal of Biological Chemistry.

An Episulfide Cation (Thiiranium Ring) Trapped in the Active Site of HAV 3C Proteinase Inactivated by Peptide-based Ketone Inhibitors

J. Vederas, M. James, L. Eltis, 2006, Journal of Molecular Biology.

Crystal Structure of the Vitamin B12 Biosynthetic Cobaltochelatase, CbiXS, from Archaeoglobus Fulgidus

M. James, A. Savchenko, J. Walker, 2006, Journal of Structural and Functional Genomics.

Crystal structure of scytalidoglutamic peptidase with its first potent inhibitor provides insights into substrate specificity and catalysis.

M. James, K. Hiraga, K. Oda, 2007, Journal of molecular biology.

Dual Modes of Modification of Hepatitis A Virus 3C Protease by a Serine-derived β-Lactone: Selective Crystallization and Formation of a Functional Catalytic Triad in the Active Site

J. Vederas, M. James, Jiang Yin, 2005, Journal of Molecular Biology.

Refined X-ray crystallographic structure of the poliovirus 3C gene product.

M. James, S. Sia, S. Mosimann, 1997, Journal of molecular biology.

Structure determination of Ascaris pepsin inhibitor-3 by MAD phasing

M. James, B. Dunn, K. Ng, 2000 .

Structure of Arterivirus nsp4

M. James, A. Gorbalenya, K. Ng, 2002, The Journal of Biological Chemistry.

NleH defines a new family of bacterial effector kinases.

S. Phanse, M. Babu, M. Cygler, 2014, Structure.

The molecular structure of ornithine acetyltransferase from Mycobacterium tuberculosis bound to ornithine, a competitive inhibitor.

M. James, R. Sankaranarayanan, Chunying Niu, 2010, Journal of molecular biology.

Crystal structure of an inhibitor complex of the 3C proteinase from hepatitis A virus (HAV) and implications for the polyprotein processing in HAV.

J. Vederas, M. James, B. Malcolm, 1999, Virology.

Crystallographic structure of human beta-hexosaminidase A: interpretation of Tay-Sachs mutations and loss of GM2 ganglioside hydrolysis.

S. Withers, M. James, M. J. Lemieux, 2006, Journal of molecular biology.

Non-nucleoside inhibitors binding to hepatitis C virus NS5B polymerase reveal a novel mechanism of inhibition.

Meitian Wang, Darius Bilimoria, M. James, 2006, Journal of molecular biology.

Crystal Structures of the RNA-dependent RNA Polymerase Genotype 2a of Hepatitis C Virus Reveal Two Conformations and Suggest Mechanisms of Inhibition by Non-nucleoside Inhibitors*

Meitian Wang, Darius Bilimoria, M. James, 2005, Journal of Biological Chemistry.

Crystal structure of sulfide:quinone oxidoreductase from Acidithiobacillus ferrooxidans: insights into sulfidotrophic respiration and detoxification.

M. James, M. Solomonson, J. Weiner, 2010, Journal of molecular biology.

Dynamics of catalysis revealed from the crystal structures of mutants of diaminopimelate epimerase.

J. Vederas, M. James, J. Blanchard, 2007, Biochemical and biophysical research communications.

Structure-activity characterization of sulfide:quinone oxidoreductase variants.

M. James, J. Weiner, Yanfei Zhang, 2012, Journal of structural biology.

The Crystal Structure of 1-D-myo-Inosityl 2-Acetamido-2-deoxy-α-D-glucopyranoside Deacetylase (MshB) from Mycobacterium tuberculosis Reveals a Zinc Hydrolase with a Lactate Dehydrogenase Fold*

D. Arad, M. James, G. Newton, 2003, Journal of Biological Chemistry.

The molecular structure of Rv1873, a conserved hypothetical protein from Mycobacterium tuberculosis, at 1.38 A resolution.

M. James, C. Garen, E. Bergmann, 2006, Acta crystallographica. Section F, Structural biology and crystallization communications.

Structural insights into the activation of P. vivax plasmepsin.

J. Dame, M. James, C. Yowell, 2003, Journal of molecular biology.

The crystal structure of the rhomboid peptidase from Haemophilus influenzae provides insight into intramembrane proteolysis

M. James, M. J. Lemieux, K. Bateman, 2007, Proceedings of the National Academy of Sciences.

Crystal structure of N-acetyl-gamma-glutamyl-phosphate reductase from Mycobacterium tuberculosis in complex with NADP(+).

M. James, L. Cherney, Chunying Niu, 2006, Journal of molecular biology.

Structure of the subtilisin Carlsberg-OMTKY3 complex reveals two different ovomucoid conformations.

M. Qasim, M. James, M. Laskowski, 2005, Acta crystallographica. Section D, Biological crystallography.

The molecular structure and catalytic mechanism of a novel carboxyl peptidase from Scytalidium lignicolum.

M. James, M. Fujinaga, K. Oda, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Unbound Form of Tomato Inhibitor-II Reveals Interdomain Flexibility and Conformational Variability in the Reactive Site Loops*

M. James, K. Ng, G. Pearce, 2003, Journal of Biological Chemistry.

Structural Basis of Inhibition Revealed by a 1:2 Complex of the Two-headed Tomato Inhibitor-II and Subtilisin Carlsberg*

M. James, K. Ng, G. Pearce, 2003, Journal of Biological Chemistry.

Structural basis for the inhibition of porcine pepsin by Ascaris pepsin inhibitor-3

M. James, B. Dunn, K. Ng, 2000, Nature Structural Biology.

Crystal structure of diaminopimelate epimerase from Arabidopsis thaliana, an amino acid racemase critical for L-lysine biosynthesis.

J. Vederas, M. James, S. Marcus, 2009, Journal of molecular biology.

Structural insights into stereochemical inversion by diaminopimelate epimerase: an antibacterial drug target.

J. Vederas, M. James, J. Blanchard, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Crystal structures of protein phosphatase-1 bound to motuporin and dihydromicrocystin-LA: elucidation of the mechanism of enzyme inhibition by cyanobacterial toxins.

M. James, David E. Williams, R. Andersen, 2006, Journal of molecular biology.

Mechanism of substrate recognition and PLP-induced conformational changes in LL-diaminopimelate aminotransferase from Arabidopsis thaliana.

J. Vederas, M. James, N. Watanabe, 2008, Journal of molecular biology.

The molecular structure of epoxide hydrolase B from Mycobacterium tuberculosis and its complex with a urea-based inhibitor.

M. James, B. Hammock, C. Morisseau, 2008, Journal of molecular biology.

The crystal structure of Rv0793, a hypothetical monooxygenase from M.␣tuberculosis

M. James, M. J. Lemieux, C. Garen, 2006, Journal of Structural and Functional Genomics.

Conformational flexibility of PL12 family heparinases: structure and substrate specificity of heparinase III from Bacteroides thetaiotaomicron (BT4657)

D. Tieleman, R. Linhardt, R. Shi, 2017, Glycobiology.

Structural Biology Conformational fl exibility of PL 12 family heparinases : structure and substrate speci fi city of heparinase III from Bacteroides thetaiotaomicron ( BT 4657 )

D. Tieleman, R. Linhardt, R. Shi, 2017 .

X-ray crystal structure of Mycobacterium tuberculosis haloalkane dehalogenase Rv2579.

M. James, C. Garen, M. Cherney, 2008, Biochimica et biophysica acta.

Cloning, expression, purification, crystallization and preliminary X-ray studies of epoxide hydrolases A and B from Mycobacterium tuberculosis.

M. James, C. Garen, M. Cherney, 2006, Acta crystallographica. Section F, Structural biology and crystallization communications.

Crystal structure of the novel aspartic proteinase zymogen proplasmepsin II from Plasmodium falciparum

Robert G. Ridley, M. James, H. Loetscher, 1999, Nature Structural Biology.

The structure of the 2A proteinase from a common cold virus: a proteinase responsible for the shut‐off of host‐cell protein synthesis

M. James, E. Kuechler, T. Skern, 1999, The EMBO journal.

Structure of Shiga Toxin Type 2 (Stx2) from Escherichia coli O157:H7*

M. James, M. Fujinaga, M. Fraser, 2004, Journal of Biological Chemistry.

Expression, purification and preliminary crystallographic analysis of Rv2247, the β subunit of acyl-CoA carboxylase (ACCD6) from Mycobacterium tuberculosis.

M. James, Jiang Yin, Chunying Niu, 2011, Acta crystallographica. Section F, Structural biology and crystallization communications.

Binding of adenine to Stx2, the protein toxin from Escherichia coli O157:H7.

M. James, P. Marcato, G. Armstrong, 2006, Acta crystallographica. Section F, Structural biology and crystallization communications.

A Mechanistic View of Enzyme Inhibition and Peptide Hydrolysis in the Active Site of the SARS-CoV 3C-like Peptidase

J. Vederas, M. James, L. Eltis, 2007, Journal of Molecular Biology.

Structure of arterivirus nsp4-The smallest chymotrypsin- like protease with an / -C-terminal extension and alternate conformations of the oxyanion hole

M. James, A. Gorbalenya, K. Ng, 2008 .

Crystal Structure and Mutagenesis of a Protein Phosphatase-1:Calcineurin Hybrid Elucidate the Role of the β12-β13 Loop in Inhibitor Binding*

M. James, C. Holmes, J. Maynes, 2004, Journal of Biological Chemistry.

Crystal structure of β-hexosaminidase B in complex with pyrimethamine, a potential pharmacological chaperone.

M. James, K. Bateman, D. Mahuran, 2011, Journal of medicinal chemistry.

Structure of the N-terminal domain of the effector protein LegC3 from Legionella pneumophila.

M. Cygler, D. Yao, M. Cherney, 2014, Acta crystallographica. Section D, Biological crystallography.

A case study on the treatment of protein SIRAS data.

M. Cygler, Pu Han, H. Fan, 2014, Acta crystallographica. Section D, Biological crystallography.

Crystal structure of the intermediate complex of the arginine repressor from Mycobacterium tuberculosis bound with its DNA operator reveals detailed mechanism of arginine repression.

M. James, L. Cherney, C. Garen, 2010, Journal of molecular biology.

Crystal structure of the arginine repressor protein in complex with the DNA operator from Mycobacterium tuberculosis.

M. James, George J. Lu, L. Cherney, 2008, Journal of molecular biology.

Structure of the C-terminal domain of the arginine repressor protein from Mycobacterium tuberculosis.

M. James, George J. Lu, L. Cherney, 2008, Acta crystallographica. Section D, Biological crystallography.

Expression, purification and preliminary X-ray analysis of the C-terminal domain of an arginine repressor protein from Mycobacterium tuberculosis.

M. James, George J. Lu, L. Cherney, 2007, Acta Crystallographica. Section F : Structural Biology and Crystallization Communications.

Expression, purification and preliminary crystallographic analysis of N-acetylglucosamine-1-phosphate uridylyltransferase from Mycobacterium tuberculosis.

M. James, Jiang Yin, L. Cherney, 2008, Acta crystallographica. Section F, Structural biology and crystallization communications.

Crystal Structures Reveal an Induced-fit Binding of a Substrate-like Aza-peptide Epoxide to SARS Coronavirus Main Peptidase

M. James, L. Eltis, Jie Liu, 2006, Journal of Molecular Biology.

Crystallographic Structure of Human b -Hexosaminidase A: Interpretation of Tay-Sachs Mutations and Loss of G M2 Ganglioside Hydrolysis

D. Mahuran, M. Cherney, B. Mark, 2022 .

Crystal structure of Mycobacterium tuberculosis Rv0760c at 1.50 A resolution, a structural homolog of Delta(5)-3-ketosteroid isomerase.

M. James, C. Garen, M. Cherney, 2008, Biochimica et biophysica acta.

Crystallography of biological macromolecules

Eddy Arnold, Michael G. Rossmann, D. M. Himmel, 2001 .