Joyce P James

Heterocycle-substituted proline dipeptides as potent VLA-4 antagonists.

B. Muñoz, M. F. Gardner, Bowei Wang, 2010, Bioorganic & medicinal chemistry letters.

Discovery of N-{N-[(3-cyanobenzene) sulfonyl]-4(R)-(3,3-difluoropiperidin-1-yl)-(l)-prolyl}-4-[(3',5'-dichloro-isonicotinoyl) amino]-(l)-phenylalanine (MK-0617), a highly potent and orally active VLA-4 antagonist.

S. Venkatraman, B. Muñoz, Bowei Wang, 2009, Bioorganic & medicinal chemistry letters.