A. Rivkin

发表

On the remarkable antitumor properties of fludelone: how we got there.

T. Chou, S. Danishefsky, A. Rivkin, 2005 .

Targeting IRAK3 for Degradation to Enhance IL-12 Pro-inflammatory Cytokine Production.

Ryan A McClure, R. Mathew, T. Kinoshita, 2022, ACS chemical biology.

Discovery and Optimization of DNA Gyrase and Topoisomerase IV Inhibitors with Potent Activity against Fluoroquinolone-Resistant Gram-Positive Bacteria.

Sarah L. Williams, D. Bussiere, X. Ling, 2021, Journal of medicinal chemistry.

Samarium(II) iodide mediated radical/polar crossover reactions of cyclobutenes. An efficient approach to the BCD ring system of the penitrems.

D. Curran, A. Rivkin, T. Nagashima, 2003, Organic letters.

Radical and palladium-catalyzed cyclizations to cyclobutenes: an entry to the BCD ring system of penitrem D.

D. Curran, A. Rivkin, Felix Gonzalez-Lopez de Turiso, 2004, The Journal of organic chemistry.

Evaluation of JAK3 Biology in Autoimmune Disease Using a Highly Selective, Irreversible JAK3 Inhibitor

Irena Ivanovska, C. Chiu, I. Kariv, 2017, The Journal of Pharmacology and Experimental Therapeutics.

Potent benzoazepinone γ-secretase modulators with improved bioavailability.

C. Kenific, A. Szewczak, C. Moxham, 2015, Bioorganic & medicinal chemistry letters.

Design and total synthesis of a superior family of epothilone analogues, which eliminate xenograft tumors to a nonrelapsable state.

T. Chou, S. Danishefsky, Y. Cho, 2003, Angewandte Chemie.

Solvent-free microwave synthesis of novel 6-hydroxypyrimidin-4(1H)-one derivatives using arylmalonates

Stephanie M. Chichetti, Sean P. Ahearn, A. Rivkin, 2007 .

Solvent-free microwave synthesis of 4-hydroxy-3-phenylquinolin-2(1H)-ones and variants using activated arylmalonates

A. Rivkin, B. Adams, 2006 .

Use of allylic triflones for allylation of C-H bonds

P. Fuchs, J. Xiang, D. Curran, 1998 .

On the remarkable antitumor properties of fludelone: how we got there.

Alexey Rivkin, T. Chou, S. Danishefsky, 2005, Angewandte Chemie.

Purine derivatives as potent gamma-secretase modulators.

C. Kenific, A. Szewczak, J. Crispino, 2010, Bioorganic & medicinal chemistry letters.

On the introduction of a trifluoromethyl substituent in the epothilone setting: chemical issues related to ring forming olefin metathesis and earliest biological findings.

T. Chou, S. Danishefsky, Kaustav Biswas, 2002, Organic letters.

Quasiracemic synthesis: concepts and implementation with a fluorous tagging strategy to make both enantiomers of pyridovericin and mappicine.

D. Curran, Qisheng Zhang, A. Rivkin, 2002, Journal of the American Chemical Society.

Application of ring-closing metathesis reactions in the synthesis of epothilones.

S. Danishefsky, Y. Cho, A. Rivkin, 2004, Journal of natural products.

Discovery of (E)-9,10-dehydroepothilones through chemical synthesis: on the emergence of 26-trifluoro-(E)-9,10-dehydro-12,13-desoxyepothilone B as a promising anticancer drug candidate.

T. Chou, S. Danishefsky, Y. Cho, 2004, Journal of the American Chemical Society.

Topoisomerase Inhibitors Addressing Fluoroquinolone Resistance in Gram-Negative Bacteria.

Sarah L. Williams, D. Bussiere, Sylvia Ma, 2020, Journal of medicinal chemistry.

Complex target-oriented total synthesis in the drug discovery process: the discovery of a highly promising family of second generation epothilones.

Alexey Rivkin, T. Chou, S. Danishefsky, 2003, Journal of the American Chemical Society.

A novel strategy for the synthesis of uracil derivatives using bis(pentafluorophenyl)imidodicarbonate

Stephanie M. Chichetti, Sean P. Ahearn, A. Rivkin, 2008 .

3-Aryl-4-hydroxyquinolin-2(1H)-one derivatives as type I fatty acid synthase inhibitors.

M. Tota, S. Krauss, I. Kariv, 2006, Bioorganic & medicinal chemistry letters.

Development of a cyclosporin A derivative with excellent anti-hepatitis C virus potency.

Li Cao, R. L. Simmons, Aregahegn Yifru, 2017, Bioorganic & medicinal chemistry.

Potent nonimmunosuppressive cyclophilin inhibitors with improved pharmaceutical properties and decreased transporter inhibition.

D. Bednarczyk, Imad Hanna, K. Leung, 2014, Journal of medicinal chemistry.

Structural basis for therapeutic inhibition of influenza A polymerase PB2 subunit

Charles A. Wartchow, W. Zhong, D. Bussiere, 2017, Scientific Reports.

In Vitro and In Vivo Properties of CUO246, a Novel Bacterial DNA Gyrase/Topoisomerase IV Inhibitor

Sylvia Ma, J. Leeds, C. Dean, 2022, Antimicrobial agents and chemotherapy.

Piperazinyl pyrimidine derivatives as potent gamma-secretase modulators.

Alexey Rivkin, Chaomin Li, A. Szewczak, 2010, Bioorganic & Medicinal Chemistry Letters.

Synthesis and conformational analysis of (E)-9,10-dehydroepothilone B: a suggestive link between the chemistry and biology of epothilones.

T. Chou, S. Danishefsky, G. Sukenick, 2003, Angewandte Chemie.