Hoda Metwally

Strategies toward Discovery of Potent and Orally Bioavailable Proteolysis Targeting Chimera Degraders of Androgen Receptor for the Treatment of Prostate Cancer.

Shaomeng Wang, D. McEachern, B. Miao, 2021, Journal of medicinal chemistry.

Discovery of ARD-2585 as an Exceptionally Potent and Orally Active PROTAC Degrader of Androgen Receptor for the Treatment of Advanced Prostate Cancer.

Shaomeng Wang, D. McEachern, B. Miao, 2021, Journal of medicinal chemistry.

A selective small-molecule STAT5 PROTAC degrader capable of achieving tumor regression in vivo

Wei Jiang, J. Stuckey, D. McEachern, 2023, Nature Chemical Biology.

Discovery of ARD-2051 as a Potent and Orally Efficacious Proteolysis Targeting Chimera (PROTAC) Degrader of Androgen Receptor for the Treatment of Advanced Prostate Cancer.

D. McEachern, B. Miao, Mi Wang, 2023, Journal of medicinal chemistry.