Wenqing Chen

发表

Biosynthesis of C-nucleoside antibiotics in actinobacteria: recent advances and future developments

Z. Deng, S. Donadio, M. Sosio, 2022, Microbial Cell Factories.

Identification of Mur34 as the Novel Negative Regulator Responsible for the Biosynthesis of Muraymycin in Streptomyces sp. NRRL30471

Z. Deng, Dongmei Xu, Xinhua Lu, 2013, PloS one.

Microbiological assay for quantitative determination of polyoxin B

Z. Deng, J. Zhong, Wenqing Chen, 2009 .

Activation of Natural Products Biosynthetic Pathways via a Protein Modification Level Regulation.

Xudong Qu, Zixin Deng, Gregory K Pierens, 2017, ACS chemical biology.

Genetic dissection of the polyoxin building block-carbamoylpolyoxamic acid biosynthesis revealing the “pathway redundancy” in metabolic networks

Z. Deng, Daofeng Dai, Tingting Huang, 2013, Microbial Cell Factories.

Enhancement of the Diversity of Polyoxins by a Thymine-7-Hydroxylase Homolog outside the Polyoxin Biosynthesis Gene Cluster

Z. Deng, Tingting Huang, Wenqing Chen, 2010, Applied and Environmental Microbiology.

polR, a pathway-specific transcriptional regulatory gene, positively controls polyoxin biosynthesis in Streptomyces cacaoi subsp. asoensis.

Z. Deng, Delin You, Yuqing Tian, 2009, Microbiology.

Deciphering Carbamoylpolyoxamic Acid Biosynthesis Reveals Unusual Acetylation Cycle Associated with Tandem Reduction and Sequential Hydroxylation.

Z. Deng, Yuhui Sun, X. Qu, 2016, Cell chemical biology.

Efficient biosynthesis of nucleoside cytokinin angustmycin A containing an unusual sugar system

Z. Deng, M. Jiang, N. Price, 2021, Nature Communications.

Harnessing synthetic biology-based strategies for engineered biosynthesis of nucleoside natural products in actinobacteria.

Z. Deng, N. Price, Le Yu, 2020, Biotechnology advances.

Comparative Investigation into Formycin A and Pyrazofurin A Biosynthesis Reveals Branch Pathways for the Construction of C-Nucleoside Scaffolds

Z. Deng, H. Cong, Wen-ting Zhou, 2019, Applied and Environmental Microbiology.

Natural and engineered biosynthesis of nucleoside antibiotics in Actinomycetes

Z. Deng, Jin Liu, Xuan Feng, 2016, Journal of Industrial Microbiology & Biotechnology.

Metabolic engineering of an industrial polyoxin producer for the targeted overproduction of designer nucleoside antibiotics

Z. Deng, Xuan Feng, G. Qiu, 2015, Biotechnology and bioengineering.

Characterization of the tunicamycin gene cluster unveiling unique steps involved in its biosynthesis

Z. Deng, Yemin Wang, Shuangjun Lin, 2010, Protein & Cell.

Characterization of the Polyoxin Biosynthetic Gene Cluster from Streptomyces cacaoi and Engineered Production of Polyoxin H*

Z. Deng, L. Bai, Delin You, 2009, Journal of Biological Chemistry.

Biosynthesis of 2′-Chloropentostatin and 2′-Amino-2′-Deoxyadenosine Highlights a Single Gene Cluster Responsible for Two Independent Pathways in Actinomadura sp. Strain ATCC 39365

Z. Deng, Wenqing Chen, You-sheng Cai, 2017, Applied and Environmental Microbiology.

Biosynthesis of 2 ’-chloropentostatin and 2 ’-amino-2 ’-deoxyadenosine 1 highlights a single gene cluster performing two independent pathways 2 in Actinomadura sp . ATCC 39365 3

Z. Deng, Wenqing Chen, You-sheng Cai, 2017 .

Structural Insight into the Catalytic Mechanism of Non-Heme Iron Halogenase AdaV in 2′-Chloropentostatin Biosynthesis

Zhengyu Zhang, Guoqing Zhai, Zixin Deng, 2022, ACS Catalysis.

Characterization of the aurantimycin biosynthetic gene cluster and enhancing its production by manipulating two pathway-specific activators in Streptomyces aurantiacus JA 4570

Z. Deng, Liang Wang, Jianzhao Qi, 2016, Microbial Cell Factories.

Biosynthesis of 4-aminoheptose 2-epimers, core structural components of the septacidins and spicamycins

N. Price, Jianzhao Qi, D. Crich, 2014, The Journal of Antibiotics.

Divergent Biosynthesis of C-Nucleoside Minimycin and Indigoidine in Bacteria

W. Tao, Z. Deng, Yu Zheng, 2019, iScience.

PolY, a transcriptional regulator with ATPase activity, directly activates transcription of polR in polyoxin biosynthesis in Streptomyces cacaoi

Z. Deng, Gang Liu, H. Tan, 2010, Molecular microbiology.

Coordinated Biosynthesis of the Purine Nucleoside Antibiotics Aristeromycin and Coformycin in Actinomycetes

Z. Deng, K. Hong, M. Jiang, 2018, Applied and Environmental Microbiology.

An Unusual Protector-Protégé Strategy for the Biosynthesis of Purine Nucleoside Antibiotics.

Z. Deng, Yong-Quan Li, Xiao-Xia Chen, 2017, Cell chemical biology.

Identification of the gene cluster involved in muraymycin biosynthesis from Streptomyces sp. NRRL 30471.

Z. Deng, Dongmei Xu, Shuangjun Lin, 2011, Molecular bioSystems.

EEG characteristics of children with attention-deficit/hyperactivity disorder

Li Sun, He Chen, Xiaoli Li, 2019, Neuroscience.

Identification and characterization of the pyridomycin biosynthetic gene cluster of Streptomyces pyridomyceticus NRRL B-2517.

Z. Deng, Jun Yin, Yemin Wang, 2011, The Journal of biological chemistry.

An ATP-Dependent Ligase with Substrate Flexibility Involved in Assembly of the Peptidyl Nucleoside Antibiotic Polyoxin

M. Wang, Z. Deng, N. Price, 2018, Applied and Environmental Microbiology.

An unusual UMP C-5 methylase in nucleoside antibiotic polyoxin biosynthesis

Z. Deng, Renxiao Wang, Jiahai Zhou, 2016, Protein & Cell.

Discovery and characterization of the tubercidin biosynthetic pathway from Streptomyces tubercidicus NBRC 13090

Z. Deng, Jianguo Wu, Qi Zhang, 2018, Microbial Cell Factories.

Engineering of an industrial polyoxin producer for the rational production of hybrid peptidyl nucleoside antibiotics.

Z. Deng, Shuangjun Lin, Xuechuan Hong, 2012, Metabolic Engineering.

An unusual UMP C-5 methylase in nucleoside antibiotic polyoxin biosynthesis

Z. Deng, Renxiao Wang, Jiahai Zhou, 2016, Protein & Cell.

Construction of an octosyl acid backbone catalyzed by a radical S-adenosylmethionine enzyme and a phosphatase in the biosynthesis of high-carbon sugar nucleoside antibiotics

Baofu Xu, Youli Xiao, Jianzhao Qi, 2016, Chemical science.

Identification of the gene cluster involved in muraymycin biosynthesis from Streptomyces sp. NRRL 30471.

Z. Deng, Shuangjun Lin, Xiu-fen Zhou, 2011, Molecular bioSystems.