M. Osabe

发表

Phosphorylated Nuclear Receptor CAR Forms a Homodimer To Repress Its Constitutive Activity for Ligand Activation

L. Perera, T. Sueyoshi, M. Negishi, 2017, Molecular and Cellular Biology.

Allopurinol suppresses expression of the regulatory T‐cell migration factors TARC/CCL17 and MDC/CCL22 in HaCaT keratinocytes via restriction of nuclear factor‐κB activation

M. Tohkin, M. Osabe, Toshiyuki Tajika, 2018, Journal of applied toxicology : JAT.

Effect of metal cations on misincorporation by E. coli DNA polymerases.

M. Miyaki, I. Murata, T. Ono, 1977, Biochemical and biophysical research communications.

Comparison of enzymatically synthesized inulin, resistant maltodextrin and clofibrate effects on biomarkers of metabolic disease in rats fed a high-fat and high-sucrose (cafeteria) diet

A. Ikari, Y. Yamazaki, J. Sugatani, 2008, European journal of nutrition.

Expression of CAR in SW480 and HepG2 cells during G1 is associated with cell proliferation.

A. Ikari, Y. Yamazaki, J. Sugatani, 2008, Biochemical and biophysical research communications.

Dietary Inulin Alleviates Hepatic Steatosis and Xenobiotics-Induced Liver Injury in Rats Fed a High-Fat and High-Sucrose Diet: Association with the Suppression of Hepatic Cytochrome P450 and Hepatocyte Nuclear Factor 4α Expression

J. Sugatani, K. Yoshinari, M. Miwa, 2006, Drug Metabolism and Disposition.

Dietary inulin alleviates hepatic steatosis and xenobiotics-induced liver injury in rats fed a high-fat and high-sucrose diet: Association with the suppression of hepatic cytochrome P450 and HNF4 α expression

J. Sugatani, K. Yoshinari, M. Miwa, 2006 .

Dephosphorylation of Threonine 38 Is Required for Nuclear Translocation and Activation of Human Xenobiotic Receptor CAR (NR1I3)*

L. Perera, T. Sueyoshi, M. Negishi, 2009, The Journal of Biological Chemistry.

Up‐regulation of CAR expression through Elk‐1 in HepG2 and SW480 cells by serum starvation stress

A. Ikari, Y. Yamazaki, J. Sugatani, 2009, FEBS letters.

Mutagenicity of α-hydroxy N-nitrosamines in V79 Chinese hamster cells

M. Mochizuki, M. Okada, M. Osabe, 1984, Journal of Cancer Research and Clinical Oncology.

Urinary metabolites of N-nitrosodibutylamine and N-nitrodibutylamine in the rat: identification of N-acetyl-S-alkyl-L-cysteines.

T. Ishizaka, M. Okada, M. Osabe, 1987, Japanese journal of cancer research : Gann.

In vitro metabolism of N-nitrodialkylamines.

M. Mochizuki, M. Okada, M. Osabe, 1985, Japanese journal of cancer research : Gann.

Expression of Hepatic UDP-Glucuronosyltransferase 1A1 and 1A6 Correlated with Increased Expression of the Nuclear Constitutive Androstane Receptor and Peroxisome Proliferator-Activated Receptor α in Male Rats Fed a High-Fat and High-Sucrose Diets⃞

A. Ikari, J. Sugatani, S. Ikushiro, 2008, Drug Metabolism and Disposition.

Active ERK1/2 Protein Interacts with the Phosphorylated Nuclear Constitutive Active/Androstane Receptor (CAR; NR1I3), Repressing Dephosphorylation and Sequestering CAR in the Cytoplasm*

M. Negishi, M. Osabe, 2011, The Journal of Biological Chemistry.

Transcriptional regulation of human UGT1A1 gene expression through distal and proximal promoter motifs: implication of defects in the UGT1A1 gene promoter

M. Mori, A. Ikari, J. Sugatani, 2008, Naunyn-Schmiedeberg's Archives of Pharmacology.

Contribution of alpha 1-acid glycoprotein to species difference in lincosamides-plasma protein binding kinetics.

M. Shimoda, E. Kokue, M. Osabe, 1998, Journal of veterinary pharmacology and therapeutics.

Clinical study designs and patient selection methods based on genomic biomarkers: Points-to-consider documents.

S. Iida, Yoshiro Saito, M. Tohkin, 2020, Drug metabolism and pharmacokinetics.

Induction of UGT1A1 and CYP2B6 by an Antimitogenic Factor in HepG2 Cells Is Mediated through Suppression of Cyclin-Dependent Kinase 2 Activity: Cell Cycle-Dependent Expression

A. Ikari, J. Sugatani, N. Kitamura, 2010, Drug Metabolism and Disposition.