B. Lippa

发表

Synthesis of the First Members of a New Class of Biologically Active Bryostatin Analogues

Makoto Shiozaki, P. Wender, M. Koehler, 1998 .

Identification of novel series of pyrazole and indole-urea based DFG-out PYK2 inhibitors.

Jacquelyn L. Klug-McLeod, Daniel P. Walker, David A. Price, 2012, Bioorganic & medicinal chemistry letters.

The practical synthesis of a novel and highly potent analogue of bryostatin.

P. Wender, J. Baryza, S. E. Brenner, 2002, Journal of the American Chemical Society.

Synthesis and biological evaluation of fully synthetic bryostatin analogues

K. Hinkle, P. Wender, P. Harran, 1998 .

The rational design of potential chemotherapeutic agents: Synthesis of bryostatin analogues

K. Hinkle, P. Wender, M. Koehler, 1999, Medicinal research reviews.

Inhibitors of Akt Activity

B. Lippa, 2007 .

Discovery of Indazole Derivatives as a Novel Class of Bacterial Gyrase B Inhibitors.

R. Dolle, Qingyi Yang, T. Moy, 2015, ACS medicinal chemistry letters.

Fragment-based discovery of DNA gyrase inhibitors targeting the ATPase subunit of GyrB.

R. Cheng, C. Scheich, M. Mesleh, 2016, Bioorganic & medicinal chemistry letters.

A novel photo-assisted annulation reaction for the synthesis of 6,7-dichloroimidazo[4,5-b]quinolin-2-one

L. Townsend, Zhijian Zhu, B. Lippa, 1996 .

Design, synthesis, and biological evaluation of tricyclic nucleosides (dimensional probes) as analogues of certain antiviral polyhalogenated benzimidazole ribonucleosides.

L. Townsend, J. Drach, B. Lippa, 2000, Journal of medicinal chemistry.

Synthesis and Biological Evaluation of Bryostatin Analogues: The Role of the A-Ring.

P. Wender, B. Lippa, 2000 .

Selective binding of bryostatin analogues to the cysteine rich domains of protein kinase C isozymes.

H. Ohigashi, K. Irie, P. Wender, 1999, Bioorganic & medicinal chemistry letters.

Design of selective, ATP-competitive inhibitors of Akt.

Tracey Clark, Matthew Marx, Blaise Lippa, 2010, Journal of medicinal chemistry.

The design, computer modeling, solution structure, and biological evaluation of synthetic analogs of bryostatin 1.

P. Wender, M. Koehler, P. Harran, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Synthesis and structure based optimization of novel Akt inhibitors.

Tracey Clark, Blaise Lippa, J. Pandit, 2008, Bioorganic & medicinal chemistry letters.

Discovery of novel isothiazole inhibitors of the TrkA kinase: structure-activity relationship, computer modeling, optimization, and identification of highly potent antagonists.

Matthew D. Wessel, Joel Morris, M. Wessel, 2006, Bioorganic & medicinal chemistry letters.

Discovery of Pyrazolopyridones as a Novel Class of Gyrase B Inhibitors Using Structure Guided Design.

M. Mesleh, J. Barker, R. Dolle, 2016, ACS medicinal chemistry letters.

Discovery of Novel Isothiazole Inhibitors of the TrkA Kinase: Structure—Activity Relationship, Computer Modeling, Optimization, and Identification of Highly Potent Antagonists.

B. Lippa, 2006 .

Biarylsulfonamide CCR9 inhibitors for inflammatory bowel disease.

Jing Zhang, Jan Romero, Sabrina Stucka, 2015, Bioorganic & medicinal chemistry letters.

In-silico guided discovery of novel CCR9 antagonists

Jing Zhang, Katie Hall, Yuchuan Wu, 2018, Journal of Computer-Aided Molecular Design.

The Hedgehog signaling pathway as a target for anticancer drug discovery.

Blaise Lippa, Gary V Borzillo, G. Borzillo, 2005, Current topics in medicinal chemistry.

595 Inhibition of integrin αvβ8 in combination with low dose radiation induces antitumor effect in advanced immune checkpoint blockade refractory tumor model

A. Ray, D. Troast, S. Krueger, 2021, Journal for ImmunoTherapy of Cancer.

Biarylsulfonamide CCR9 inhibitors for inflammatory bowel disease.

J. Cross, M. Varoglu, B. Lippa, 2015, Bioorganic & medicinal chemistry letters.

Discovery of indole inhibitors of chemokine receptor 9 (CCR9).

Bhaumik A. Pandya, M. Varoglu, B. Lippa, 2016, Bioorganic & medicinal chemistry letters.

The discovery of highly selective erbB2 (Her2) inhibitors for the treatment of cancer.

L. Pustilnik, S. Bhattacharya, J. Chen, 2007, Bioorganic & medicinal chemistry letters.