R. Schnur

发表

Depletion of the erbB-2 gene product p185 by benzoquinoid ansamycins.

P. Miller, A. Bruskin, C. Diorio, 1994, Cancer research.

Depletion of p185erbB2, Raf-1 and mutant p53 proteins by geldanamycin derivatives correlates with antiproliferative activity

L. Neckers, M. Blagosklonny, W. An, 1997, Cancer Chemotherapy and Pharmacology.

p185erbB2 binds to GRP94 in vivo. Dissociation of the p185erbB2/GRP94 heterocomplex by benzoquinone ansamycins precedes depletion of p185erbB2.

L. Neckers, J. Trepel, E. Mimnaugh, 1996, The Journal of biological chemistry.

Preparation of 17-amino-22-(4′-azido-3′-125iodophenacyl)-17-demethoxygeldanamycin (1): An ansamycin for photoaffinity labeling

R. Schnur, M. Corman, 1994 .

p185 Binds to GRP94 in Vivo

L. Neckers, J. Trepel, E. Mimnaugh, 1996, The Journal of Biological Chemistry.

Binding of benzoquinoid ansamycins to p100 correlates with their ability to deplete the erbB2 gene product p185.

P. Miller, M. Moyer, J. Moyer, 1994, Biochemical and biophysical research communications.

erbB-2 oncogene inhibition by geldanamycin derivatives: synthesis, mechanism of action, and structure-activity relationships.

P. Miller, C. Diorio, M. Dee, 1995, Journal of medicinal chemistry.

Inhibition of the oncogene product p185erbB-2 in vitro and in vivo by geldanamycin and dihydrogeldanamycin derivatives.

C. Diorio, M. Dee, J. Moyer, 1995, Journal of medicinal chemistry.

Tandem [3,3]-sigmatropic rearrangements in an ansamycin : stereospecific conversion of an (S)-allylic alcohol to an (S)-allylic amine derivative

R. Schnur, M. Corman, 1994 .

Spiro hydantoin aldose reductase inhibitors.

M. Peterson, J. Belletire, R. Sarges, 1988, Journal of medicinal chemistry.

A generalized and proton-catalyzed synthesis of amidines from thioimidates

R. Schnur, 1979 .

N-(5-fluorobenzothiazol-2-yl)-2-guanidinothiazole-4-carboxamide. A novel, systemically active antitumor agent effective against 3LL Lewis lung carcinoma.

A. Fliri, S. Kajiji, R. Schnur, 1991, Journal of medicinal chemistry.

Dehydrations with N-methyl-N,N'-di-tert-butylcarbodiimidium ion

R. Schnur, E. E. Tamelen, 1975 .

Selective N-dealkylation of tertiary amines with vinyl chloroformate: An improved synthesis of naloxone

R. Schnur, R. A. Olofson, J. P. Pepe, 1977 .

Synthesis of 1 - deuterioaldehydes from methylene - BIS - pyridinium cations

D. Zimmerman, R. Schnur, R. A. Olofson, 1972 .

Synthesis of novel 1,3-oxazino[6,5-b]indole-2,4-(3H,9H)-dione and 2H-1,3,5-oxadiazino[3,2-a]indole-2,4-(3H)-dione from oxindoles

R. Schnur, Randall J. Gallaschun and, 1992 .

Value of the vinyloxycarbonyl unit in hydroxyl protection: application to the synthesis of nalorphine

R. Schnur, R. A. Olofson, 1977 .

In vitro microbiological characterization of novel cyclic homopentapeptides, CP-101,680 and CP-163,234, for animal health use.

J. Dirlam, R. Schnur, J. Retsema, 1999, The Journal of antibiotics.

SELECTIVE N-DEALKYLATION OF TERTIARY AMINES WITH VINYL CHLOROFORMATE- AN IMPROVED SYNTHESIS OF NALOXONE

R. Schnur, R. A. Olofson, J. P. Pepe, 1977 .

Spiro oxazolidinedione aldose reductase inhibitors.

M. Peterson, R. Sarges, R. Schnur, 1982, Journal of medicinal chemistry.

Rotationally restricted mimics of rigid molecules: nonspirocyclic hydantoin aldose reductase inhibitors.

P. Kelbaugh, K. Kraus, R. Schnur, 1989, Journal of medicinal chemistry.