Hua Lin

发表

Assessment of NR4A Ligands That Directly Bind and Modulate the Orphan Nuclear Receptor Nurr1.

Ian Mitchelle S. de Vera, D. Kojetin, T. Kamenecka, 2020, Journal of medicinal chemistry.

TNP [N2-(m-Trifluorobenzyl), N6-(p-nitrobenzyl)purine] ameliorates diet induced obesity and insulin resistance via inhibition of the IP6K1 pathway

J. Barrow, Haifei Xu, Baoji Xu, 2016, Molecular metabolism.

Structure-Activity Relationship and Biological Investigation of SR18292 (16), a Suppressor of Glucagon-Induced Glucose Production.

P. Puigserver, P. Griffin, K. Sharabi, 2021, Journal of medicinal chemistry.

Discovery of Hydrolysis-Resistant Isoindoline N-Acyl Amino Acid Analogues that Stimulate Mitochondrial Respiration.

B. Spiegelman, P. Griffin, D. Nomura, 2018, Journal of medicinal chemistry.

Native Directed Site-Selective δ-C(sp3)–H and δ-C(sp2)–H Arylation of Primary Amines

T. Bannister, T. Kamenecka, Hua Lin, 2019, ACS Catalysis.

Synthesis of novel steroidal agonists, partial agonists, and antagonists for the glucocorticoid receptor.

J. Nwachukwu, S. Srinivasan, N. Bruno, 2017, Bioorganic & medicinal chemistry letters.

Cooperative cobinding of synthetic and natural ligands to the nuclear receptor PPARγ

T. Hughes, D. Kojetin, S. Mosure, 2018, bioRxiv.

1 Cooperative Cobinding of Synthetic and Natural 2 Ligands to the Nuclear Receptor PPARγ 3

T. Hughes, D. Kojetin, S. Mosure, 2022 .

The Secreted Enzyme PM20D1 Regulates Lipidated Amino Acid Uncouplers of Mitochondria

B. Spiegelman, S. Gygi, J. Paulo, 2016, Cell.

Selective Chemical Inhibition of PGC-1α Gluconeogenic Activity Ameliorates Type 2 Diabetes

Joshua A. Bittker, P. Puigserver, S. Schreiber, 2017, Cell.

Site-Selective γ-C(sp3 )-H and γ-C(sp2 )-H Arylation of Free Amino Esters Promoted by a Catalytic Transient Directing Group.

T. Bannister, T. Kamenecka, Chao Wang, 2018, Chemistry.

Ablation of PM20D1 reveals N-acyl amino acid control of metabolism and nociception

Amir I. Mina, Alexander S. Banks, B. Spiegelman, 2018, Proceedings of the National Academy of Sciences.

Modification of the Orthosteric PPARγ Covalent Antagonist Scaffold Yields an Improved Dual-Site Allosteric Inhibitor.

D. Kojetin, J. Fuhrmann, T. Kamenecka, 2017, ACS chemical biology.

Design, synthesis, and evaluation of simple phenol amides as ERRγ agonists.

Ruben D. Garcia-Ordonez, P. Griffin, M. Cameron, 2018, Bioorganic & Medicinal Chemistry Letters.

Assessment of NR4A Ligands that Directly Bind and Modulate the Orphan Nuclear Receptor Nurr1

Ian Mitchelle S. de Vera, D. Kojetin, T. Kamenecka, 2020, bioRxiv.

Methamphetamine Learning Induces Persistent and Selective Nonmuscle Myosin II-Dependent Spine Motility in the Basolateral Amygdala

G. Rumbaugh, Courtney A. Miller, T. Kamenecka, 2020, The Journal of Neuroscience.

Methamphetamine learning induces persistent nonmuscle myosin II-dependent spine motility in the basolateral amygdala

G. Rumbaugh, Courtney A. Miller, T. Kamenecka, 2019, bioRxiv.

Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with Rosiglitazone and Oleic acid

T. Hughes, D. Kojetin, S. Mosure, 2018 .